Arsenic exposure disrupts the normal function of the FA/BRCA repair pathway

Toxicological Sciences

Volumn 142, Issue 1, 2014, Pages 93-104

  Peremartí, Jana ^a   Ramos, Facundo ^a   Marcos, Ricard ^a,b   Hernández, Alba ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

Author keywords

DNA repair; FANCD2 deficient; Fanconi anemia FA BRCA pathway; Genomic instability; Interstrand crosslinks; Trivalent arsenic compounds

Indexed keywords

ARSENIC DERIVATIVE; ARSENIC TRIOXIDE; BUTADIENE DIEPOXIDE; FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA PROTEIN; HYDROXYUREA; METHYLARSONOUS ACID; MITOMYCIN; UNCLASSIFIED DRUG; FANCD2 PROTEIN, HUMAN; METHANEARSONIC ACID; ORGANOARSENIC DERIVATIVE; OXIDE;

ACUTE TOXICITY; ARTICLE; CARCINOGENICITY; CELL COMPARTMENTALIZATION; CELL SURVIVAL; CELL VIABILITY; CYTOTOXICITY; ENVIRONMENTAL EXPOSURE; FIBROBLAST; G2 PHASE CELL CYCLE CHECKPOINT; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; HYPERSENSITIVITY; MICRONUCLEUS TEST; PHENOTYPE; PROTEIN FUNCTION; CELL CYCLE; CELL LINE; CELL PROLIFERATION; DNA REPAIR; DRUG EFFECTS; FANCONI ANEMIA; FLOW CYTOMETRY; GENETICS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TOXICITY TESTING;

ARSENICALS; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; DNA REPAIR; FANCONI ANEMIA; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; FIBROBLASTS; FLOW CYTOMETRY; GENOMIC INSTABILITY; HUMANS; MICRONUCLEUS TESTS; OXIDES; SIGNAL TRANSDUCTION; TOXICITY TESTS, ACUTE;

EID: 84937557824     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu159     Document Type: Article

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