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Volumn 23, Issue 15, 2015, Pages 4277-4285

Stereoselective synthesis and pharmacological evaluation of [4.3.3]propellan-8-amines as analogs of adamantanamines

(7) Torres Gómez, Héctor a Lehmkuhl, Kirstin a Frehland, Bastian a Daniliuc, Constantin a Schepmann, Dirk a Ehrhardt, Christina a Wünsch, Bernhard a

a UNIVERSITY OF MÜNSTER (Germany)

Author keywords

Amantadine; Antiviral activity; NMDA receptor; PCP binding site; Propellanamines; Stereoselective synthesis

Indexed keywords

AMANTADINE; AMANTADINE DERIVATIVE; ANTIVIRUS AGENT; ANTI[4.3.3]PROPELLAN 8 AMINE; DIZOCILPINE; MEMANTINE; SYN[4.3.3]PROPELLAN 8 AMINE; UNCLASSIFIED DRUG; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHENCYCLIDINE;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INFLUENZA VIRUS A H7N7; NONHUMAN; RECEPTOR BLOCKING; STRUCTURE ANALYSIS; ANALOGS AND DERIVATIVES; ANIMAL; BINDING SITE; CELL LINE; CHEMISTRY; DOG; DRUG EFFECTS; INFLUENZA A VIRUS; MDCK CELL LINE; METABOLISM; PRECLINICAL STUDY; PROCEDURES; STATIC ELECTRICITY; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

INFLUENZA A VIRUS;

AMANTADINE; ANIMALS; ANTIVIRAL AGENTS; BINDING SITES; CELL LINE; CHEMISTRY TECHNIQUES, SYNTHETIC; CRYSTALLOGRAPHY, X-RAY; DOGS; DRUG EVALUATION, PRECLINICAL; HUMANS; INFLUENZA A VIRUS; MADIN DARBY CANINE KIDNEY CELLS; MEMANTINE; PHENCYCLIDINE; RECEPTORS, N-METHYL-D-ASPARTATE; STATIC ELECTRICITY; STEREOISOMERISM;

EID: 84937519640 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2015.06.030 Document Type: Article

Times cited : (6)

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