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Volumn 14, Issue 3, 2015, Pages 324-333

Protease-antiprotease imbalances differ between Cystic Fibrosis patients' upper and lower airway secretions

Author keywords

Cathepsin; Lung; Nasal lavage; Neutrophil elastase; Protease; Sinonasal; SLPI

Indexed keywords

CATHEPSIN S; GELATINASE B; LEUKOCYTE ELASTASE; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

EID: 84937515226     PISSN: 15691993     EISSN: 18735010     Source Type: Journal    
DOI: 10.1016/j.jcf.2014.09.003     Document Type: Article
Times cited : (18)

References (51)
  • 1
    • 79952184063 scopus 로고    scopus 로고
    • Cystic Fibrosis Foundation, Bethesda, Maryland
    • Cystic Fibrosis Foundation Patient Registry Annual data report 2010, Cystic Fibrosis Foundation, Bethesda, Maryland.
    • (2010) Annual data report
  • 2
    • 0026831341 scopus 로고
    • Mucoid Pseudomonas aeruginosa is a marker of poor survival in cystic fibrosis
    • Henry R.L., Mellis C.M., Petrovic L. Mucoid Pseudomonas aeruginosa is a marker of poor survival in cystic fibrosis. Pediatr Pulmonol Mar 1992, 12(3):158-161.
    • (1992) Pediatr Pulmonol , vol.12 , Issue.3 , pp. 158-161
    • Henry, R.L.1    Mellis, C.M.2    Petrovic, L.3
  • 3
    • 67249139656 scopus 로고    scopus 로고
    • Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis
    • Mainz J., Naehrlich L., Schien M., Kading M., Schiller I., Mayr S., et al. Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis. Thorax 2009, 64(6):535-540.
    • (2009) Thorax , vol.64 , Issue.6 , pp. 535-540
    • Mainz, J.1    Naehrlich, L.2    Schien, M.3    Kading, M.4    Schiller, I.5    Mayr, S.6
  • 4
    • 84858280044 scopus 로고    scopus 로고
    • Sinonasal persistence of Pseudomonas aeruginosa after lung transplantation
    • Mar
    • Mainz J.G., Hentschel J., Schien C., Cramer N., Pfister W., Beck J.F., et al. Sinonasal persistence of Pseudomonas aeruginosa after lung transplantation. J Cyst Fibros Mar 2012, 11(2):158-161.
    • (2012) J Cyst Fibros , vol.11 , Issue.2 , pp. 158-161
    • Mainz, J.G.1    Hentschel, J.2    Schien, C.3    Cramer, N.4    Pfister, W.5    Beck, J.F.6
  • 7
    • 0036010034 scopus 로고    scopus 로고
    • Nasal lavage as a tool for the assessment of upper-airway inflammation in adults and children
    • Mar
    • Nikasinovic-Fournier L., Just J., Seta N., Callais F., Sahraoui F., Grimfeld A., et al. Nasal lavage as a tool for the assessment of upper-airway inflammation in adults and children. J Lab Clin Med Mar 2002, 139(3):173-180.
    • (2002) J Lab Clin Med , vol.139 , Issue.3 , pp. 173-180
    • Nikasinovic-Fournier, L.1    Just, J.2    Seta, N.3    Callais, F.4    Sahraoui, F.5    Grimfeld, A.6
  • 9
    • 76249114693 scopus 로고    scopus 로고
    • Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation
    • Weldon S., McNally P., McElvaney N.G., Elborn J.S., McAuley D.F., Wartelle J., et al. Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation. J Immunol Dec 15 2009, 183(12):8148-8156.
    • (2009) J Immunol , vol.183 , Issue.12 , pp. 8148-8156
    • Weldon, S.1    McNally, P.2    McElvaney, N.G.3    Elborn, J.S.4    McAuley, D.F.5    Wartelle, J.6
  • 10
    • 58149394958 scopus 로고    scopus 로고
    • Inhibition of airway proteases in cystic fibrosis lung disease
    • Griese M., Kappler M., Gaggar A., Hartl D. Inhibition of airway proteases in cystic fibrosis lung disease. Eur Respir J September 1 2008, 32(3):783-795.
    • (2008) Eur Respir J , vol.32 , Issue.3 , pp. 783-795
    • Griese, M.1    Kappler, M.2    Gaggar, A.3    Hartl, D.4
  • 11
    • 0028962836 scopus 로고
    • Proteases and antiproteases in cystic fibrosis: pathogenetic considerations and therapeutic strategies
    • Birrer P. Proteases and antiproteases in cystic fibrosis: pathogenetic considerations and therapeutic strategies. Respiration 1995, 62(Suppl. 1):25-28.
    • (1995) Respiration , vol.62 , pp. 25-28
    • Birrer, P.1
  • 12
    • 0030448955 scopus 로고    scopus 로고
    • Use of secretory leukoprotease inhibitor to augment lung antineutrophil elastase activity
    • Vogelmeier C., Gillissen A., Buhl R. Use of secretory leukoprotease inhibitor to augment lung antineutrophil elastase activity. Chest Dec 1996, 110(6 Suppl.):261S-266S.
    • (1996) Chest , vol.110 , Issue.6 , pp. 261S-266S
    • Vogelmeier, C.1    Gillissen, A.2    Buhl, R.3
  • 13
    • 84884830109 scopus 로고    scopus 로고
    • Specific cleavage of the lung surfactant protein A by human cathepsin S may impair its antibacterial properties
    • Lecaille F., Naudin C., Sage J., Joulin-Giet A., Courty A., Andrault P.M., et al. Specific cleavage of the lung surfactant protein A by human cathepsin S may impair its antibacterial properties. Int J Biochem Cell Biol Aug 2013, 45(8):1701-1709.
    • (2013) Int J Biochem Cell Biol , vol.45 , Issue.8 , pp. 1701-1709
    • Lecaille, F.1    Naudin, C.2    Sage, J.3    Joulin-Giet, A.4    Courty, A.5    Andrault, P.M.6
  • 14
    • 0035823570 scopus 로고    scopus 로고
    • Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor
    • Taggart C.C., Lowe G.J., Greene C.M., Mulgrew A.T., O'Neill S.J., Levine R.L., et al. Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor. J Biol Chem September 7 2001, 276(36):33345-33352.
    • (2001) J Biol Chem , vol.276 , Issue.36 , pp. 33345-33352
    • Taggart, C.C.1    Lowe, G.J.2    Greene, C.M.3    Mulgrew, A.T.4    O'Neill, S.J.5    Levine, R.L.6
  • 15
    • 82755167524 scopus 로고    scopus 로고
    • Cathepsins and their involvement in immune responses
    • Conus S., Simon H.U. Cathepsins and their involvement in immune responses. Swiss Med Wkly 2010, 140:w13042.
    • (2010) Swiss Med Wkly , vol.140 , pp. w13042
    • Conus, S.1    Simon, H.U.2
  • 17
    • 16244368754 scopus 로고    scopus 로고
    • Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis
    • Sagel S., Kapsner R., Osberg I. Induced sputum matrix metalloproteinase-9 correlates with lung function and airway inflammation in children with cystic fibrosis. Pediatr Pulmonol 2005, 39(3):224-232.
    • (2005) Pediatr Pulmonol , vol.39 , Issue.3 , pp. 224-232
    • Sagel, S.1    Kapsner, R.2    Osberg, I.3
  • 18
    • 69549105799 scopus 로고    scopus 로고
    • Serum matrix metalloproteinases in adult CF patients: relation to pulmonary exacerbation
    • Roderfeld M., Rath T., Schulz R., Seeger W., Tschuschner A., Graf J., et al. Serum matrix metalloproteinases in adult CF patients: relation to pulmonary exacerbation. J Cyst Fibros Sep 2009, 8(5):338-347.
    • (2009) J Cyst Fibros , vol.8 , Issue.5 , pp. 338-347
    • Roderfeld, M.1    Rath, T.2    Schulz, R.3    Seeger, W.4    Tschuschner, A.5    Graf, J.6
  • 19
    • 34447522038 scopus 로고    scopus 로고
    • Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients
    • Gaggar A., Li Y., Weathington N., Winkler M., Kong M., Jackson P., et al. Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients. Am J Physiol Lung Cell Mol Physiol Jul 2007, 293(1):L96-L104.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293 , Issue.1 , pp. L96-L104
    • Gaggar, A.1    Li, Y.2    Weathington, N.3    Winkler, M.4    Kong, M.5    Jackson, P.6
  • 20
    • 77951951482 scopus 로고    scopus 로고
    • Human neutrophil elastase-mediated cleavage sites of MMP-9 and TIMP-1: implications to cystic fibrosis proteolytic dysfunction
    • [Research Support, N.I.H., Extramural]
    • Jackson P.L., Xu X., Wilson L., Weathington N.M., Clancy J.P., Blalock J.E., et al. Human neutrophil elastase-mediated cleavage sites of MMP-9 and TIMP-1: implications to cystic fibrosis proteolytic dysfunction. Mol Med May-Jun 2010, 16(5-6):159-166. [Research Support, N.I.H., Extramural].
    • (2010) Mol Med , vol.16 , Issue.5-6 , pp. 159-166
    • Jackson, P.L.1    Xu, X.2    Wilson, L.3    Weathington, N.M.4    Clancy, J.P.5    Blalock, J.E.6
  • 21
    • 84884764818 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their impact on sinusal extension in chronic rhinosinusitis with nasal polyps
    • Malinsky R.R., Valera F.C., Cavallari F.E., Kupper D.S., Milaneze C., Silva J.S., et al. Matrix metalloproteinases and their impact on sinusal extension in chronic rhinosinusitis with nasal polyps. Eur Arch Otorhinolaryngol Mar 2013, 270(4):1345-1348.
    • (2013) Eur Arch Otorhinolaryngol , vol.270 , Issue.4 , pp. 1345-1348
    • Malinsky, R.R.1    Valera, F.C.2    Cavallari, F.E.3    Kupper, D.S.4    Milaneze, C.5    Silva, J.S.6
  • 22
    • 33847616086 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in the respiratory tracts of human infants following paramyxovirus infection
    • Elliott M.B., Welliver R.C., Laughlin T.S., Pryharski K.S., LaPierre N.A., Chen T., et al. Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in the respiratory tracts of human infants following paramyxovirus infection. J Med Virol 2007, 79(4):447-456.
    • (2007) J Med Virol , vol.79 , Issue.4 , pp. 447-456
    • Elliott, M.B.1    Welliver, R.C.2    Laughlin, T.S.3    Pryharski, K.S.4    LaPierre, N.A.5    Chen, T.6
  • 24
    • 0028129568 scopus 로고
    • Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis
    • Fuchs H.J., Borowitz D.S., Christiansen D.H., Morris E.M., Nash M.L., Ramsey B.W., et al. Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. N Engl J Med 1994, 331(10):637-642.
    • (1994) N Engl J Med , vol.331 , Issue.10 , pp. 637-642
    • Fuchs, H.J.1    Borowitz, D.S.2    Christiansen, D.H.3    Morris, E.M.4    Nash, M.L.5    Ramsey, B.W.6
  • 25
    • 85006410596 scopus 로고    scopus 로고
    • Non-invasive assessment of upper and lower airway infection and inflammation in CF patients
    • [Epub ahead of print]
    • Fischer N., Hentschel J., Markert U.R., Keller P.M., Pletz M.W., Mainz J.G. Non-invasive assessment of upper and lower airway infection and inflammation in CF patients. Pediatr Pulmonol Jan 25 2014, [Epub ahead of print]. 10.1002/ppul.22982.
    • (2014) Pediatr Pulmonol
    • Fischer, N.1    Hentschel, J.2    Markert, U.R.3    Keller, P.M.4    Pletz, M.W.5    Mainz, J.G.6
  • 26
    • 84896714488 scopus 로고    scopus 로고
    • Influences of nasal lavage collection-, processing- and storage methods on inflammatory markers - evaluation of a method for non-invasive sampling of epithelial lining fluid in cystic fibrosis and other respiratory diseases
    • Hentschel J., Muller U., Doht F., Fischer N., Boer K., Sonnemann J., et al. Influences of nasal lavage collection-, processing- and storage methods on inflammatory markers - evaluation of a method for non-invasive sampling of epithelial lining fluid in cystic fibrosis and other respiratory diseases. J Immunol Methods Feb 2014, 404:41-51.
    • (2014) J Immunol Methods , vol.404 , pp. 41-51
    • Hentschel, J.1    Muller, U.2    Doht, F.3    Fischer, N.4    Boer, K.5    Sonnemann, J.6
  • 27
    • 77958025778 scopus 로고    scopus 로고
    • Novel method to process cystic fibrosis sputum for determination of oxidative state
    • Hector A., Jonas F., Kappler M., Feilcke M., Hartl D., Griese M. Novel method to process cystic fibrosis sputum for determination of oxidative state. Respiration 2010, 80(5):393-400.
    • (2010) Respiration , vol.80 , Issue.5 , pp. 393-400
    • Hector, A.1    Jonas, F.2    Kappler, M.3    Feilcke, M.4    Hartl, D.5    Griese, M.6
  • 29
    • 84876991913 scopus 로고    scopus 로고
    • Soluble inflammation markers in nasal lavage from CF patients and healthy controls
    • Beiersdorf N., Schien M., Hentschel J., Pfister W., Markert U.R., Mainz J.G. Soluble inflammation markers in nasal lavage from CF patients and healthy controls. J Cyst Fibros May 2013, 12(3):249-257.
    • (2013) J Cyst Fibros , vol.12 , Issue.3 , pp. 249-257
    • Beiersdorf, N.1    Schien, M.2    Hentschel, J.3    Pfister, W.4    Markert, U.R.5    Mainz, J.G.6
  • 31
    • 67650712233 scopus 로고    scopus 로고
    • Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening
    • Sly P.D., Brennan S., Gangell C., de Klerk N., Murray C., Mott L., et al. Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening. Am J Respir Crit Care Med Jul 15 2009, 180(2):146-152.
    • (2009) Am J Respir Crit Care Med , vol.180 , Issue.2 , pp. 146-152
    • Sly, P.D.1    Brennan, S.2    Gangell, C.3    de Klerk, N.4    Murray, C.5    Mott, L.6
  • 32
    • 81055139582 scopus 로고    scopus 로고
    • Cystic fibrosis upper airways primary colonization with Pseudomonas aeruginosa: eradicated by sinonasal antibiotic inhalation
    • [Letter]
    • Mainz J.G., Michl R., Pfister W., Beck J.F. Cystic fibrosis upper airways primary colonization with Pseudomonas aeruginosa: eradicated by sinonasal antibiotic inhalation. Am J Respir Crit Care Med Nov 1 2011, 184(9):1089-1090. [Letter].
    • (2011) Am J Respir Crit Care Med , vol.184 , Issue.9 , pp. 1089-1090
    • Mainz, J.G.1    Michl, R.2    Pfister, W.3    Beck, J.F.4
  • 33
    • 34548282581 scopus 로고    scopus 로고
    • Sputum biomarkers of inflammation in cystic fibrosis lung disease
    • Sagel S.D., Chmiel J.F., Konstan M.W. Sputum biomarkers of inflammation in cystic fibrosis lung disease. Proc Am Thorac Soc Aug 1 2007, 4(4):406-417.
    • (2007) Proc Am Thorac Soc , vol.4 , Issue.4 , pp. 406-417
    • Sagel, S.D.1    Chmiel, J.F.2    Konstan, M.W.3
  • 34
    • 84870745042 scopus 로고    scopus 로고
    • Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization
    • Aanaes K., Johansen H., Poulsen S., Pressler T., Buchwald C., Hoiby N. Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization. J Cyst Fibros 2013, 12(1):81-87.
    • (2013) J Cyst Fibros , vol.12 , Issue.1 , pp. 81-87
    • Aanaes, K.1    Johansen, H.2    Poulsen, S.3    Pressler, T.4    Buchwald, C.5    Hoiby, N.6
  • 35
    • 84874223141 scopus 로고    scopus 로고
    • NET balancing: a problem in inflammatory lung diseases
    • Cheng O.Z., Palaniyar N. NET balancing: a problem in inflammatory lung diseases. Front Immunol 2013, 4:1.
    • (2013) Front Immunol , vol.4 , pp. 1
    • Cheng, O.Z.1    Palaniyar, N.2
  • 36
    • 84900866624 scopus 로고    scopus 로고
    • Dynamics of soluble and cellular inflammatory markers in nasal lavage obtained from Cystic Fibrosis patients during intravenous antibiotic treatment
    • Hentschel J., Jager M., Beiersdorf N., Fischer N., Doht F., Michl R., et al. Dynamics of soluble and cellular inflammatory markers in nasal lavage obtained from Cystic Fibrosis patients during intravenous antibiotic treatment. BMC Pulm Med 2014, 14(1):82.
    • (2014) BMC Pulm Med , vol.14 , Issue.1 , pp. 82
    • Hentschel, J.1    Jager, M.2    Beiersdorf, N.3    Fischer, N.4    Doht, F.5    Michl, R.6
  • 37
    • 0344624839 scopus 로고    scopus 로고
    • Long-term azithromycin may improve lung function in children with cystic fibrosis
    • [Letter]
    • Jaffe A., Francis J., Rosenthal M., Bush A. Long-term azithromycin may improve lung function in children with cystic fibrosis. Lancet Feb 7 1998, 351(9100):420. [Letter].
    • (1998) Lancet , vol.351 , Issue.9100 , pp. 420
    • Jaffe, A.1    Francis, J.2    Rosenthal, M.3    Bush, A.4
  • 38
    • 84860202479 scopus 로고    scopus 로고
    • Protection of lung epithelial cells from protease-mediated injury by trappin-2 A62L, an engineered inhibitor of neutrophil serine proteases
    • Tanga A., Saidi A., Jourdan M.L., Dallet-Choisy S., Zani M.L., Moreau T. Protection of lung epithelial cells from protease-mediated injury by trappin-2 A62L, an engineered inhibitor of neutrophil serine proteases. Biochem Pharmacol Jun 15 2012, 83(12):1663-1673.
    • (2012) Biochem Pharmacol , vol.83 , Issue.12 , pp. 1663-1673
    • Tanga, A.1    Saidi, A.2    Jourdan, M.L.3    Dallet-Choisy, S.4    Zani, M.L.5    Moreau, T.6
  • 39
    • 34249779564 scopus 로고    scopus 로고
    • Deposition of aerosolized particles in the maxillary sinuses before and after endoscopic sinus surgery
    • St Martin M.B., Hitzman C.J., Wiedmann T.S., Rimell F.L. Deposition of aerosolized particles in the maxillary sinuses before and after endoscopic sinus surgery. Am J Rhinol Mar-Apr 2007, 21(2):196-197.
    • (2007) Am J Rhinol , vol.21 , Issue.2 , pp. 196-197
    • St Martin, M.B.1    Hitzman, C.J.2    Wiedmann, T.S.3    Rimell, F.L.4
  • 40
    • 80051734134 scopus 로고    scopus 로고
    • Nasally inhaled pulsating aerosols: lung, sinus and nose deposition
    • [Research Support, Non-U.S. Gov't]
    • Moller W., Saba G.K., Haussinger K., Becker S., Keller M., Schuschnig U. Nasally inhaled pulsating aerosols: lung, sinus and nose deposition. Rhinology Aug 2011, 49(3):286-291. [Research Support, Non-U.S. Gov't].
    • (2011) Rhinology , vol.49 , Issue.3 , pp. 286-291
    • Moller, W.1    Saba, G.K.2    Haussinger, K.3    Becker, S.4    Keller, M.5    Schuschnig, U.6
  • 41
    • 84902328031 scopus 로고    scopus 로고
    • Sinonasal inhalation of dornase alfa administered by vibrating aerosol to cystic fibrosis patients: a double-blind placebo-controlled cross-over trial
    • Mainz J.G., Schien C., Schiller I., Schadlich K., Koitschev A., Koitschev C., et al. Sinonasal inhalation of dornase alfa administered by vibrating aerosol to cystic fibrosis patients: a double-blind placebo-controlled cross-over trial. J Cyst Fibros 2014, 13(4):461-470.
    • (2014) J Cyst Fibros , vol.13 , Issue.4 , pp. 461-470
    • Mainz, J.G.1    Schien, C.2    Schiller, I.3    Schadlich, K.4    Koitschev, A.5    Koitschev, C.6
  • 42
    • 84894697777 scopus 로고    scopus 로고
    • Sinonasal inhalation of tobramycin vibrating aerosol in cystic fibrosis patients with upper airway Pseudomonas aeruginosa colonization: results of a randomized, double-blind, placebo-controlled pilot study
    • Mainz J.G., Schadlich K., Schien C., Michl R., Schelhorn-Neise P., Koitschev A., et al. Sinonasal inhalation of tobramycin vibrating aerosol in cystic fibrosis patients with upper airway Pseudomonas aeruginosa colonization: results of a randomized, double-blind, placebo-controlled pilot study. Drug Des Devel Ther 2014, 8:209-217.
    • (2014) Drug Des Devel Ther , vol.8 , pp. 209-217
    • Mainz, J.G.1    Schadlich, K.2    Schien, C.3    Michl, R.4    Schelhorn-Neise, P.5    Koitschev, A.6
  • 43
    • 80053351926 scopus 로고    scopus 로고
    • SLPI and trappin-2 as therapeutic agents to target airway serine proteases in inflammatory lung diseases: current and future directions
    • Zani M.L., Tanga A., Saidi A., Serrano H., Dallet-Choisy S., Baranger K., et al. SLPI and trappin-2 as therapeutic agents to target airway serine proteases in inflammatory lung diseases: current and future directions. Biochem Soc Trans Oct 2011, 39(5):1441-1446.
    • (2011) Biochem Soc Trans , vol.39 , Issue.5 , pp. 1441-1446
    • Zani, M.L.1    Tanga, A.2    Saidi, A.3    Serrano, H.4    Dallet-Choisy, S.5    Baranger, K.6
  • 44
    • 77951988740 scopus 로고    scopus 로고
    • Hypertonic saline improves the LCI in paediatric patients with CF with normal lung function
    • Amin R., Subbarao P., Jabar A., Balkovec S., Jensen R., Kerrigan S., et al. Hypertonic saline improves the LCI in paediatric patients with CF with normal lung function. Thorax May 2010, 65(5):379-383.
    • (2010) Thorax , vol.65 , Issue.5 , pp. 379-383
    • Amin, R.1    Subbarao, P.2    Jabar, A.3    Balkovec, S.4    Jensen, R.5    Kerrigan, S.6
  • 45
    • 84873146970 scopus 로고    scopus 로고
    • Airway inflammatory markers in individuals with cystic fibrosis and non-cystic fibrosis bronchiectasis
    • Bergin D.A., Hurley K., Mehta A., Cox S., Ryan D., O'Neill S.J., et al. Airway inflammatory markers in individuals with cystic fibrosis and non-cystic fibrosis bronchiectasis. J Inflamm Res 2013, 6:1-11.
    • (2013) J Inflamm Res , vol.6 , pp. 1-11
    • Bergin, D.A.1    Hurley, K.2    Mehta, A.3    Cox, S.4    Ryan, D.5    O'Neill, S.J.6
  • 46
    • 84855413331 scopus 로고    scopus 로고
    • Metalloproteases/anti-metalloproteases imbalance in chronic obstructive pulmonary disease: genetic factors and treatment implications
    • [Review]
    • Mocchegiani E., Giacconi R., Costarelli L. Metalloproteases/anti-metalloproteases imbalance in chronic obstructive pulmonary disease: genetic factors and treatment implications. Curr Opin Pulm Med Dec 2011, 17(Suppl. 1):S11-S19. [Review].
    • (2011) Curr Opin Pulm Med , vol.17 , pp. S11-S19
    • Mocchegiani, E.1    Giacconi, R.2    Costarelli, L.3
  • 47
    • 80052831009 scopus 로고    scopus 로고
    • Regression of allograft airway fibrosis: the role of MMP-dependent tissue remodeling in obliterative bronchiolitis after lung transplantation
    • Sato M., Hwang D.M., Guan Z., Yeung J.C., Anraku M., Wagnetz D., et al. Regression of allograft airway fibrosis: the role of MMP-dependent tissue remodeling in obliterative bronchiolitis after lung transplantation. Am J Pathol Sep 2011, 179(3):1287-1300.
    • (2011) Am J Pathol , vol.179 , Issue.3 , pp. 1287-1300
    • Sato, M.1    Hwang, D.M.2    Guan, Z.3    Yeung, J.C.4    Anraku, M.5    Wagnetz, D.6
  • 48
    • 84890553047 scopus 로고    scopus 로고
    • The role of neutrophils in cystic fibrosis
    • Gifford A.M., Chalmers J.D. The role of neutrophils in cystic fibrosis. Curr Opin Hematol Jan 2014, 21(1):16-22.
    • (2014) Curr Opin Hematol , vol.21 , Issue.1 , pp. 16-22
    • Gifford, A.M.1    Chalmers, J.D.2
  • 49
    • 84861913437 scopus 로고    scopus 로고
    • Effect of Mediterranean diet versus prudent diet combined with physical activity on OSAS: a randomised trial
    • Papandreou C., Schiza S.E., Bouloukaki I., Hatzis C.M., Kafatos A.G., Siafakas N.M., et al. Effect of Mediterranean diet versus prudent diet combined with physical activity on OSAS: a randomised trial. Eur Respir J Jun 2012, 39(6):1398-1404.
    • (2012) Eur Respir J , vol.39 , Issue.6 , pp. 1398-1404
    • Papandreou, C.1    Schiza, S.E.2    Bouloukaki, I.3    Hatzis, C.M.4    Kafatos, A.G.5    Siafakas, N.M.6
  • 50
    • 84864135737 scopus 로고    scopus 로고
    • Use of MMP-8 and MMP-9 to assess disease severity in children with viral lower respiratory tract infections
    • Brand K.H., Ahout I.M., de Groot R., Warris A., Ferwerda G., Hermans P.W. Use of MMP-8 and MMP-9 to assess disease severity in children with viral lower respiratory tract infections. J Med Virol Sep 2012, 84(9):1471-1480.
    • (2012) J Med Virol , vol.84 , Issue.9 , pp. 1471-1480
    • Brand, K.H.1    Ahout, I.M.2    de Groot, R.3    Warris, A.4    Ferwerda, G.5    Hermans, P.W.6
  • 51
    • 33646375158 scopus 로고    scopus 로고
    • Are lower airway or throat cultures predictive of sinus bacteriology in cystic fibrosis?
    • Muhlebach M., Miller M., Moore C., Wedd J., Drake A., Leigh M. Are lower airway or throat cultures predictive of sinus bacteriology in cystic fibrosis?. Pediatr Pulmonol 2006, 41(5):445-451.
    • (2006) Pediatr Pulmonol , vol.41 , Issue.5 , pp. 445-451
    • Muhlebach, M.1    Miller, M.2    Moore, C.3    Wedd, J.4    Drake, A.5    Leigh, M.6


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