Use of secretory leukoprotease inhibitor to augment lung antineutrophil elastase activity

Chest

Volumn 110, Issue 6 SUPPL., 1996, Pages 261S-266S

  Vogelmeier, Claus ^a   Gillissen, Adrian ^b   Buhl, Roland ^c  

^a UNIVERSITY OF MUNICH   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

antiproteases; secretory leukoprotease inhibitor; therapy

Indexed keywords

LEUKOCYTE ELASTASE; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR;

CYSTIC FIBROSIS; DRUG EFFECT; DRUG SCREENING; ENZYME INHIBITION; INHALATIONAL DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; REVIEW;

EID: 0030448955     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.110.6_Supplement.261S     Document Type: Article

References (58)

1. Haendle H, Fritz H, Trautschold I, et al. Über einen hormonabhängigen inhibitor für proteolytische Enzyme in männlichen accessorischen Geschlechtsdrüsen und im Sperma. Hoppe Seyler Z Physiol Chem 1965; 343:185-88
2. Hochstrasser K, Reichert R, Schwarz S, et al. Isolierung und Charakterisierung eines Proteaseninhibitors aus menschlichem Bronchialsekret. Hoppe Seyler Z Physiol Chem 1972; 353:221-26
3. Wallner O, Fritz H. Characterization of an acid-stable proteinase inhibitor in human cervical mucus. Hoppe Seyler Z Physiol Chem 1974; 355:709-15
4. Casslen B. Inhibitors of trypsin, chymotrypsin and elastase in human uterine fluid. Acta Obstet Gynecol Scand 1986; 65:121-24
5. Franken C, Meijer CJLM, Dijkman JH. Tissue distribution of antileukoprotease and lysozyme in humans. J Histochem Cytochem 1989; 37:493-98
6. Böhm B, Deutzmann R, Burkhardt H. Purification of a serine-proteinase inhibitor from human articular cartilage. Biochem J 1991; 274:269-73
7. Fritz H. Human mucus proteinase inhibitor (human MPI). Biol Chem Hoppe-Seyler 1988; 369:79-82
8. Eisenberg SP, Hale KK, Heimdal P, et al. Location of the protease-inhibitory region of secretory leukocyte protease inhibitor. J Biol Chem 1990; 265:7976-81
9. Kramps JA, van Twisk Ch, Appelhans H, et al. Proteinase inhibitory activities of antileukoprotease are represented by its second COOH-terminal domain. Biochim Biophys Acta 1990; 1038: 178-85
10. Van-Seuningen I, Davril M. Separation of the two domains of human mucus proteinase inhibitor: inhibitory activity is only located in the carboxy-terminal domain. Biochem Biophys Res Commun 1991; 179:1587-92
11. Seemüller U, Arnhold M, Fritz H, et al. The acid-stable proteinase inhibitor of human mucous secretions (HUSI-I, antileukoprotease). FEBS Lett 1986; 199:43-8
12. Thompson RC, Ohlsson K. Isolation, properties, and complete amino acid sequence of human secretory leukocyte protease inhibitor, a potent inhibitor of leukocyte elastase. Proc Natl Acad Sci USA 1986; 83:6692-96
13. Boudier C, Carvallo D, Roitsch C, et al. Purification and characterization of human bronchial proteinase inhibitor. Arch Biochem Biophys 1987; 253:439-45
14. Grütter MG, Fendrich G, Huber R, et al. The 2.5 Å x-ray crystal structure of the acid-stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha-chymotrypsin. EMBO J 1988; 7:345-51
15. Hubbard RC, Crystal RG. Antiproteases. In: Crystal RG, West JB, Barnes PJ, et al, eds. The lung - scientific foundations. New York: Raven Press, 1991; 1775-87
16. Stetler G, Brewer MT, Thompson RC. Isolation and sequence of a human gene encoding a potent inhibitor of leukocyte proteases. Nucleic Acids Res 1986; 14:7883-96
17. Gauthier F, Fryksmark U, Ohlsson K, et al. Kinetics of the inhibition of leukocyte elastase by the bronchial inhibitor. Biochem Biophys Acta 1982; 700:178-83
18. Smith CE, Johnson DA. Human bronchial leucocyte proteinase inhibitor. Biochem J 1985; 225:463-72
19. Fink E, Nettelbeck R, Fritz H. Inhibition of mast cell chymase by eglin c and antileukoprotease (HUSI-I). Biol Chem Hoppe Seyler 1986; 367:567-71
20. Travis J, Fritz H. Potential problems in designing elastase inhibitors for therapy. Am Rev Respir Dis 1991; 143:1412-15
21. Junger WG, Hallström S, Redl H, et al. Inhibition of human, ovine, and baboon neutrophil elastase with eglin c and secretory leukocyte proteinase inhibitor. Biol Chem Hoppe Seyler 1992; 373:119-22
22. Fryksmark U, Ohlsson K, Polling A, et al. Distribution of antileukoprotease in upper respiratory mucosa. Ann Otol Rhinol Laryngol 1982; 91:268-71
23. Mooren HWD, Kramps JA, Franken C, et al. Localisation of a low-molecular-weight bronchial protease inhibitor in the peripheral human lung. Thorax 1983; 38:180-83
24. De Water R, Willems LNA, Van Muijen GNP, et al. Ultrastructural localization of bronchial antileukoprotease in central and peripheral human airways by a gold-labeling technique using monoclonal antibodies. Am Rev Respir Dis 1986; 133:882-90
25. Willems LNA, Otto-Verberne CJM, Kramps JA, et al. Detection of antileukoprotease in connective tissue of lung. Histochemistry 1986; 86:165-68
26. Abe T, Kobayashi N, Yoshimura K, et al. Expression of the secretory leukoprotease inhibitor gene in epithelial cells. J Clin Invest 1991; 87:2207-15
27. 1-proteinase inhibitor in peripheral airspaces of the human lung. Clin Sci 1988; 75:351-53
28. Morrison HM, Kramps JA, Dijkman JH, et al. Comparison of concentrations of two proteinase inhibitors, porcine pancreatic elastase inhibitory capacity, and cell profiles in sequential bronchoalveolar lavage samples. Thorax 1986; 41:435-41
29. Vogelmeier C, Hubbard RC, Fells GA, et al. Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor. J Clin Invest 1991; 87:482-88
30. 1-antitrypsin deficiency associated with emphysema. N Engl J Med 1987; 316:1055-62
31. Schmidt EW, Rasche B, Ulmer WT, et al. Replacement therapy for alpha-1-protease inhibitor deficiency in PiZ subjects with chronic obstructive lung disease. Am J Med 1988; 84:63S-9S
32. 1-antitrypsin deficiency. Am J Med 1988; 84:52S-62S
33. 1-antitrypsin. Ann Intern Med 1989; 111:206-12
34. 1-antitrypsin treatment for cystic fibrosis. Lancet 1991; 337:392-94
35. Reilly CF, Travis J. The degradation of human lung elastin by neutrophil proteinases. Biochim Biophys Acta 1980; 621:147-57
36. Hornebeck W, Schnebli HP. Effect of different elastase inhibitors on leukocyte elastase pre-adsorbed to elastin. Hoppe Seyler Z Physiol Chem 1982; 363:455-58
37. 1-proteinase inhibitor and bronchial inhibitor. Biochem J 1986; 238:269-73
38. Miller KW, Evans RJ, Eisenberg SP, et al. Secretory leukocyte protease inhibitor binding to mRNA and DNA as a possible cause of toxicity to Escherichia coli. J Bacteriol 1989; 171:2166-72
39. Kohno T, Carmichael DF, Sommer A, et al. Refolding of recombinant proteins. Methods Enzymol 1990; 185:187-95
40. Casolaro MA, Fells G, Wewers M, et al. Augmentation of lung antineutrophil elastase capacity with recombinant human alpha-1-antitrypsin. J Appl Physiol 1987; 63:2015-23
41. 1-antitrypsin as an inhibitor of neutrophil elastase. J Clin Invest 1987; 80:1366-74
42. Vogelmeier C, Buhl R, Hoyt RF, et al. Aerosolization of recombinant SLPI to augment antineutrophil elastase protection of pulmonary epithelium. J Appl Physiol 1990; 69:1843-48
43. Beatty K, Bieth J, Travis J. Kinetics of association of serine proteinases with native and oxidized alpha-1-proteinase inhibitor and alpha-1-antichymotrypsin. J Biol Chem 1980; 255:3931-34
44. 1-antitrypsin deficiency. Biochem Biophys Res Commun 1985; 130:1177-84
45. Rennard SI, Basset G, Lecossier D, et al. Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution. J Appl Physiol 1986; 60:532-38
46. Staub NC, Bland RD, Brigham KL, et al. Preparation of chronic lung lymph fistulas in sheep. J Surg Res 1975; 19:315-20
47. Snider GL. Chronic obstructive pulmonary disease: risk factors, pathophysiology and pathogenesis. Annu Rev Med 1989; 40: 411-29
48. Lucey EC, Stone PJ, Ciccolella DE, et al. Recombinant human secretory leukocyte-protease inhibitor: in vitro properties, and amelioration of human neutrophil elastase-induced emphysema and secretory cell metaplasia in the hamster. J Lab Clin Med 1990; 115:224-32
49. Rudolphus A, Stolk J, Dijkman JH, et al. Inhibition of lipopolysaccharide-induced pulmonary emphysema by intratracheally instilled recombinant secretory leukocyte proteinase inhibitor. Am Rev Respir Dis 1993; 147:442-47
50. Gast A, Anderson W, Probst A, et al. Pharmacokinetics and distribution of recombinant secretory leukocyte proteinase inhibitor in rats. Am Rev Respir Dis 1990; 141:889-94
51. Birrer P, McElvaney NG, Gillissen A, et al. Intravenous recombinant secretory leukoprotease inhibitor augments antineutrophil elastase defense. J Appl Physiol 1992; 73:317-23
52. Baggiolini M, Walz A, Kunkel SL. Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils. J Clin Invest 1989; 84:1045-49
53. Nakamura H, Yoshimura K, McElvaney NG, et al. Neutrophil elastase in respiratory epithelial lining fluid of individuals with cystic fibrosis induces interleukin-8 gene expression in a human bronchial epithelial cell line. J Clin Invest 1992; 89:1478-84
54. McElvaney NG, Nakamura H, Birrer P, et al. Modulation of airway inflammation in cystic fibrosis. J Clin Invest 1992; 90:1296-1301
55. Gillissen A, Birrer P, Buhl R, et al. Recombinant secretory leukoprotease inhibitor augments glutathione levels in respiratory epithelial lining fluid. J Appl Phjsiol 1993; 75:825-32
56. Buhl R, Vogelmeier C, Critenden M, et al. Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol. Proc Natl Acad Sci USA 1990; 87:4063-67
57. Griffith OW, Meister A. Glutathione: interorgan translocation, turnover, and metabolism. Proc Natl Acad Sci USA 1979; 76:5606-10
58. Meyer A, Buhl R, Magnussen H. The effect of oral N-acetylcysteine on lung glutathione levels in idiopathic pulmonary fibrosis. Eur Respir J 1994; 7:431-36