Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter

FASEB Journal

Volumn 29, Issue 2, 2015, Pages 623-635

  Parr, Callum ^a   Mirzaei, Nazanin ^a   Christian, Mark ^b   Sastre, Magdalena ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Alzheimer's disease; DKK 1; GSK3; SFRP 1

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA ACTIN; BETA CATENIN; BETA SECRETASE 1; DICKKOPF 1 PROTEIN; FRIZZLED PROTEIN; FRIZZLED RECEPTOR PROTEIN 1; GLYCOGEN SYNTHASE KINASE 3; SYNAPSIN I; T CELL FACTOR 4 PROTEIN; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT3A PROTEIN; AMYLOID PROTEIN; ASPARTIC PROTEINASE; BACE1 PROTEIN, MOUSE; BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; DKK1 PROTEIN, MOUSE; MEMBRANE PROTEIN; SECRETASE; SFRP1 PROTEIN, MOUSE; SIGNAL PEPTIDE; TCF4 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYMATIC ASSAY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROCESSING; REPRESSOR GENE; TRANSCRIPTION INITIATION SITE; WNT SIGNALING PATHWAY; ANIMAL; AUTOPHAGY; BINDING SITE; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; GENETICS; LYSOSOME; METABOLISM; PROTEIN TERTIARY STRUCTURE; REPORTER GENE; TUMOR CELL LINE;

AMYLOID PRECURSOR PROTEIN SECRETASES; AMYLOIDOGENIC PROTEINS; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; AUTOPHAGY; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BETA CATENIN; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; GENES, REPORTER; GLYCOGEN SYNTHASE KINASE 3; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYSOSOMES; MEMBRANE PROTEINS; MICE; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY; WNT SIGNALING PATHWAY;

EID: 84937428246     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.14-253211     Document Type: Article

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