-
1
-
-
80054937214
-
Executive summary: Calcific aortic valve disease-2011 update
-
Calcific aortic valve disease: not simply a degenerative process: a review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group
-
Rajamannan NM, Evans FJ, Aikawa E, et al. Calcific aortic valve disease: not simply a degenerative process: a review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: calcific aortic valve disease-2011 update. Circulation. 2011;124:1783-1791.
-
(2011)
Circulation
, vol.124
, pp. 1783-1791
-
-
Rajamannan, N.M.1
Evans, F.J.2
Aikawa, E.3
-
2
-
-
79958147911
-
Calcific aortic valve stenosis: Methods, models, and mechanisms
-
Miller JD, Weiss RM, Heistad DD. Calcific aortic valve stenosis: methods, models, and mechanisms. Circ Res. 2011;108:1392-1412.
-
(2011)
Circ Res
, vol.108
, pp. 1392-1412
-
-
Miller, J.D.1
Weiss, R.M.2
Heistad, D.D.3
-
3
-
-
84868628871
-
Cellular mechanisms of aortic valve calcification
-
Leopold JA. Cellular mechanisms of aortic valve calcification. Circ Cardiovasc Interv. 2012;5:605-614.
-
(2012)
Circ Cardiovasc Interv
, vol.5
, pp. 605-614
-
-
Leopold, J.A.1
-
4
-
-
80052174320
-
The regulation of valvular and vascular sclerosis by osteogenic morphogens
-
Bostrom KI, Rajamannan NM, Towler DA. The regulation of valvular and vascular sclerosis by osteogenic morphogens. Circ Res. 2011;109:564-577.
-
(2011)
Circ Res
, vol.109
, pp. 564-577
-
-
Bostrom, K.I.1
Rajamannan, N.M.2
Towler, D.A.3
-
5
-
-
34948907257
-
Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries: Role of bone morphogenic protein antagonists in inflammation and atherosclerosis
-
Chang K, Weiss D, Suo J, et al. Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries: role of bone morphogenic protein antagonists in inflammation and atherosclerosis. Circulation. 2007;116:1258-1266.
-
(2007)
Circulation
, vol.116
, pp. 1258-1266
-
-
Chang, K.1
Weiss, D.2
Suo, J.3
-
6
-
-
79952397401
-
Contribution of bone morphogenetic protein-2 to aortic valve calcification in aged rat
-
Seya K, Yu Z, Kanemaru K, et al. Contribution of bone morphogenetic protein-2 to aortic valve calcification in aged rat. J Pharmacol Sci. 2011; 115:8-14.
-
(2011)
J Pharmacol Sci
, vol.115
, pp. 8-14
-
-
Seya, K.1
Yu, Z.2
Kanemaru, K.3
-
7
-
-
84865206803
-
MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-beta1 pathway
-
Pan Z, Sun X, Shan H, et al. MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-beta1 pathway. Circulation. 2012;126:840-850.
-
(2012)
Circulation
, vol.126
, pp. 840-850
-
-
Pan, Z.1
Sun, X.2
Shan, H.3
-
8
-
-
79961095592
-
Biogenesis and regulation of cardiovascular microRNAs
-
Bauersachs J, Thum T. Biogenesis and regulation of cardiovascular microRNAs. Circ Res. 2011;109:334-347.
-
(2011)
Circ Res
, vol.109
, pp. 334-347
-
-
Bauersachs, J.1
Thum, T.2
-
9
-
-
84930271043
-
MicroRNA signature and cardiovascular dysfunction
-
Nov 10 [Epub ahead of print]
-
Arunachalam G, Upadhyay R, Ding H, et al. MicroRNA signature and cardiovascular dysfunction. J Cardiovasc Pharmacol. 2014 Nov 10 [Epub ahead of print].
-
(2014)
J Cardiovasc Pharmacol
-
-
Arunachalam, G.1
Upadhyay, R.2
Ding, H.3
-
10
-
-
84892396920
-
Methyl jasmonate sensitizes human bladder cancer cells to gambogic acid-induced apoptosis through downregulation of EZH2 expression by MIR-101
-
Wang Y, Xiang W, Wang M, et al. Methyl jasmonate sensitizes human bladder cancer cells to gambogic acid-induced apoptosis through downregulation of EZH2 expression by MIR-101. Br J Pharmacol. 2014;171: 618-635.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 618-635
-
-
Wang, Y.1
Xiang, W.2
Wang, M.3
-
11
-
-
84924424616
-
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment
-
Cheng CJ, Bahal R, Babar IA, et al. MicroRNA silencing for cancer therapy targeted to the tumour microenvironment. Nature. 2015;518: 107-110.
-
(2015)
Nature
, vol.518
, pp. 107-110
-
-
Cheng, C.J.1
Bahal, R.2
Babar, I.A.3
-
12
-
-
84876392367
-
MicroRNA in cardiovascular calcification: Focus on targets and extracellular vesicle delivery mechanisms
-
Goettsch C, Hutcheson JD, Aikawa E. MicroRNA in cardiovascular calcification: focus on targets and extracellular vesicle delivery mechanisms. Circ Res. 2013;112:1073-1084.
-
(2013)
Circ Res
, vol.112
, pp. 1073-1084
-
-
Goettsch, C.1
Hutcheson, J.D.2
Aikawa, E.3
-
13
-
-
84928650382
-
MicroRNAs regulate vascular medial calcification
-
Leopold JA. MicroRNAs regulate vascular medial calcification. Cells. 2014;3:963-980.
-
(2014)
Cells
, vol.3
, pp. 963-980
-
-
Leopold, J.A.1
-
14
-
-
84871872493
-
Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by MIR-29 repression mediates vascular smooth muscle calcification
-
Du Y, Gao C, Liu Z, et al. Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by MIR-29 repression mediates vascular smooth muscle calcification. Arterioscler Thromb Vasc Biol. 2012;32:2580-2588.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 2580-2588
-
-
Du, Y.1
Gao, C.2
Liu, Z.3
-
15
-
-
84867739025
-
MicroRNA-204 regulates vascular smooth muscle cell calcification in vitro and in vivo
-
Cui RR, Li SJ, Liu LJ, et al. MicroRNA-204 regulates vascular smooth muscle cell calcification in vitro and in vivo. Cardiovasc Res. 2012;96: 320-329.
-
(2012)
Cardiovasc Res
, vol.96
, pp. 320-329
-
-
Cui, R.R.1
Li, S.J.2
Liu, L.J.3
-
16
-
-
84857497016
-
Human myxomatous mitral valve prolapse: Role of bone morphogenetic protein 4 in valvular interstitial cell activation
-
Sainger R, Grau JB, Branchetti E, et al. Human myxomatous mitral valve prolapse: role of bone morphogenetic protein 4 in valvular interstitial cell activation. J Cell Physiol. 2012;227:2595-2604.
-
(2012)
J Cell Physiol
, vol.227
, pp. 2595-2604
-
-
Sainger, R.1
Grau, J.B.2
Branchetti, E.3
-
17
-
-
70349135494
-
Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: Role of Smad1 and extracellular signal-regulated kinase 1/2
-
Yang X, Meng X, Su X, et al. Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: role of Smad1 and extracellular signal-regulated kinase 1/2. J Thorac Cardiovasc Surg. 2009;138:1008-1015.
-
(2009)
J Thorac Cardiovasc Surg
, vol.138
, pp. 1008-1015
-
-
Yang, X.1
Meng, X.2
Su, X.3
-
18
-
-
79551611520
-
Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves
-
Wirrig EE, Hinton RB, Yutzey KE. Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves. J Mol Cell Cardiol. 2011;50:561-569.
-
(2011)
J Mol Cell Cardiol
, vol.50
, pp. 561-569
-
-
Wirrig, E.E.1
Hinton, R.B.2
Yutzey, K.E.3
-
19
-
-
84921793648
-
MicroRNA-103a functions as a mechnosensitive microRNA to inhibit bone formation through targeting Runx2
-
Zuo B, Zhu JF, Li J, et al. microRNA-103a functions as a mechnosensitive microRNA to inhibit bone formation through targeting Runx2. J Bone Miner Res. 2015;30:330-345.
-
(2015)
J Bone Miner Res
, vol.30
, pp. 330-345
-
-
Zuo, B.1
Zhu, J.F.2
Li, J.3
-
20
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V. The functions of animal microRNAs. Nature. 2004;431:350-355.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
21
-
-
68449097267
-
MIR-145 and MIR-143 regulate smooth muscle cell fate and plasticity
-
Cordes KR, Sheehy NT, White MP, et al. MIR-145 and MIR-143 regulate smooth muscle cell fate and plasticity. Nature. 2009;460:705-710.
-
(2009)
Nature
, vol.460
, pp. 705-710
-
-
Cordes, K.R.1
Sheehy, N.T.2
White, M.P.3
-
22
-
-
68049083397
-
MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation
-
Cheng Y, Liu X, Yang J, et al. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ Res. 2009;105:158-166.
-
(2009)
Circ Res
, vol.105
, pp. 158-166
-
-
Cheng, Y.1
Liu, X.2
Yang, J.3
-
23
-
-
84884671476
-
MicroRNA-26 was decreased in rat cardiac hypertrophy model and may be a promising therapeutic target
-
Zhang ZH, Li J, Liu BR, et al. MicroRNA-26 was decreased in rat cardiac hypertrophy model and may be a promising therapeutic target. J Cardiovasc Pharmacol. 2013;62:312-319.
-
(2013)
J Cardiovasc Pharmacol
, vol.62
, pp. 312-319
-
-
Zh, Z.1
Li, J.2
Liu, B.R.3
-
24
-
-
84855393451
-
Look more closely at the valve: Imaging calcific aortic valve disease
-
Aikawa E, Otto CM. Look more closely at the valve: imaging calcific aortic valve disease. Circulation. 2012;125:9-11.
-
(2012)
Circulation
, vol.125
, pp. 9-11
-
-
Aikawa, E.1
Otto, C.M.2
-
25
-
-
84877975598
-
Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis
-
Poggio P, Sainger R, Branchetti E, et al. Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis. Cardiovasc Res. 2013;98:402-410.
-
(2013)
Cardiovasc Res
, vol.98
, pp. 402-410
-
-
Poggio, P.1
Sainger, R.2
Branchetti, E.3
-
26
-
-
84899957532
-
The mammalian target of rapamycin signalling pathway is involved in osteoblastic differentiation of vascular smooth muscle cells
-
Zhan JK, Wang YJ, Wang Y, et al. The mammalian target of rapamycin signalling pathway is involved in osteoblastic differentiation of vascular smooth muscle cells. Can J Cardiol. 2014;30:568-575.
-
(2014)
Can J Cardiol
, vol.30
, pp. 568-575
-
-
Zhan, J.K.1
Wang, Y.J.2
Wang, Y.3
-
27
-
-
84897499323
-
Adiponectin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the AMPK/mTOR pathway
-
Zhan JK, Wang YJ, Wang Y, et al. Adiponectin attenuates the osteoblastic differentiation of vascular smooth muscle cells through the AMPK/mTOR pathway. Exp Cell Res. 2014;323:352-358.
-
(2014)
Exp Cell Res
, vol.323
, pp. 352-358
-
-
Zhan, J.K.1
Wang, Y.J.2
Wang, Y.3
-
28
-
-
79960015376
-
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2
-
Zhang Y, Xie RL, Croce CM, et al. A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2. Proc Natl Acad Sci USA. 2011;108:9863-9868.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9863-9868
-
-
Zhang, Y.1
Xie, R.L.2
Croce, C.M.3
-
29
-
-
77149136767
-
MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation
-
Huang J, Zhao L, Xing L, et al. MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells. 2010;28:357-364.
-
(2010)
Stem Cells
, vol.28
, pp. 357-364
-
-
Huang, J.1
Zhao, L.2
Xing, L.3
-
30
-
-
84885072423
-
Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals
-
Cai Z, Li F, Gong W, et al. Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals. Arterioscler Thromb Vasc Biol. 2013;33:2345-2354.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 2345-2354
-
-
Cai, Z.1
Li, F.2
Gong, W.3
-
31
-
-
84887497888
-
Aortic valvular interstitial cells apoptosis and calcification are mediated by TNF-related apoptosis-inducing ligand
-
Galeone A, Brunetti G, Oranger A, et al. Aortic valvular interstitial cells apoptosis and calcification are mediated by TNF-related apoptosis-inducing ligand. Int J Cardiol. 2013;169:296-304.
-
(2013)
Int J Cardiol
, vol.169
, pp. 296-304
-
-
Galeone, A.1
Brunetti, G.2
Oranger, A.3
-
32
-
-
84872953219
-
Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis
-
Branchetti E, Sainger R, Poggio P, et al. Antioxidant enzymes reduce DNA damage and early activation of valvular interstitial cells in aortic valve sclerosis. Arterioscler Thromb Vasc Biol. 2013;33:66-74.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. 66-74
-
-
Branchetti, E.1
Sainger, R.2
Poggio, P.3
-
33
-
-
84908248105
-
Twist-related protein 1 negatively regulated osteoblastic transdifferentiation of human aortic valve interstitial cells by directly inhibiting runt-related transcription factor 2
-
Zhang XW, Zhang BY, Wang SW, et al. Twist-related protein 1 negatively regulated osteoblastic transdifferentiation of human aortic valve interstitial cells by directly inhibiting runt-related transcription factor 2. J Thorac Cardiovasc Surg. 2014;148:1700-1708.
-
(2014)
J Thorac Cardiovasc Surg
, vol.148
, pp. 1700-1708
-
-
Zhang, X.W.1
Zhang, B.Y.2
Wang, S.W.3
-
34
-
-
28944439309
-
Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution
-
Stark A, Brennecke J, Bushati N, et al. Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell. 2005;123:1133-1146.
-
(2005)
Cell
, vol.123
, pp. 1133-1146
-
-
Stark, A.1
Brennecke, J.2
Bushati, N.3
-
35
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120:15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
36
-
-
70349213385
-
Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster
-
Boettger T, Beetz N, Kostin S, et al. Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest. 2009;119:2634-2647.
-
(2009)
J Clin Invest
, vol.119
, pp. 2634-2647
-
-
Boettger, T.1
Beetz, N.2
Kostin, S.3
-
37
-
-
77952307133
-
MicroRNA-204/211 alters epithelial physiology
-
Wang FE, Zhang C, Maminishkis A, et al. MicroRNA-204/211 alters epithelial physiology. FASEB J. 2010;24:1552-1571.
-
(2010)
FASEB J
, vol.24
, pp. 1552-1571
-
-
Wang, F.E.1
Zhang, C.2
Maminishkis, A.3
-
38
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005;433:769-773.
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
-
39
-
-
33745248430
-
Micro RNA target predictions in animals
-
Rajewsky N. Micro RNA target predictions in animals. Nat Genet. 2006; 38(suppl):S8-S13.
-
(2006)
Nat Genet
, vol.38
, pp. S8-S13
-
-
Rajewsky, N.1
-
40
-
-
84880558743
-
Current management of calcific aortic stenosis
-
Lindman BR, Bonow RO, Otto CM. Current management of calcific aortic stenosis. Circ Res. 2013;113:223-237.
-
(2013)
Circ Res
, vol.113
, pp. 223-237
-
-
Lindman, B.R.1
Bonow, R.O.2
Otto, C.M.3
-
41
-
-
84896505147
-
Transcatheter versus surgical aortic valve replacement in patients with diabetes and severe aortic stenosis at high risk for surgery: An analysis of the PARTNER Trial (Placement of Aortic Transcatheter Valve)
-
Lindman BR, Pibarot P, Arnold SV, et al. Transcatheter versus surgical aortic valve replacement in patients with diabetes and severe aortic stenosis at high risk for surgery: an analysis of the PARTNER Trial (Placement of Aortic Transcatheter Valve). J Am Coll Cardiol. 2014;63:1090-1099.
-
(2014)
J Am Coll Cardiol
, vol.63
, pp. 1090-1099
-
-
Lindman, B.R.1
Pibarot, P.2
Arnold, S.V.3
-
42
-
-
84906318824
-
Basic mechanisms of calcific aortic valve disease
-
Mathieu P, Boulanger MC. Basic mechanisms of calcific aortic valve disease. Can J Cardiol. 2014;30:982-993.
-
(2014)
Can J Cardiol
, vol.30
, pp. 982-993
-
-
Mathieu, P.1
Boulanger, M.C.2
-
43
-
-
84879236109
-
Bone morphogenetic protein-2 decreases microRNA-30b and microRNA-30c to promote vascular smooth muscle cell calcification
-
Balderman JA, Lee HY, Mahoney CE, et al. Bone morphogenetic protein-2 decreases microRNA-30b and microRNA-30c to promote vascular smooth muscle cell calcification. J Am Heart Assoc. 2012;1:1-11.
-
(2012)
J Am Heart Assoc
, vol.1
, pp. 1-11
-
-
Balderman, J.A.1
Lee, H.Y.2
Mahoney, C.E.3
-
44
-
-
77956116784
-
Altered microRNAs in bicuspid aortic valve: A comparison between stenotic and insufficient valves
-
Nigam V, Sievers HH, Jensen BC, et al. Altered microRNAs in bicuspid aortic valve: a comparison between stenotic and insufficient valves. J Heart Valve Dis. 2010;19:459-465.
-
(2010)
J Heart Valve Dis
, vol.19
, pp. 459-465
-
-
Nigam, V.1
Sievers, H.H.2
Jensen, B.C.3
-
45
-
-
84862629212
-
MIRNA-141 is a novel regulator of BMP-2-mediated calcification in aortic stenosis
-
Yanagawa B, Lovren F, Pan Y, et al. miRNA-141 is a novel regulator of BMP-2-mediated calcification in aortic stenosis. J Thorac Cardiovasc Surg. 2012;144:256-262.
-
(2012)
J Thorac Cardiovasc Surg
, vol.144
, pp. 256-262
-
-
Yanagawa, B.1
Lovren, F.2
Pan, Y.3
|