IL-6 trans-signaling increases expression of airways disease genes in airway smooth muscle

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 309, Issue 2, 2015, Pages L129-L138

  Robinson, Mac B ^a   Deshpande, Deepak A ^b   Chou, Jeffery ^a   Cui, Wei ^a   Smith, Shelly ^a   Langefeld, Carl ^a   Hastie, Annette T ^a   Bleecker, Eugene R ^a   Hawkins, Gregory A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Airway disease; Gene expression; Human airway smooth muscle; IL 6; IL 6 trans signaling

Indexed keywords

GLUCOSE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; TRANSCRIPTION FACTOR; BIOLOGICAL MARKER; MESSENGER RNA;

AIRWAY SMOOTH MUSCLE CELL; ARTICLE; ASTHMA; CCL11 GENE; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; DAB2 GENE; DOWN REGULATION; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLUCOSE METABOLISM; HILPDA GENE; HUMAN; HUMAN CELL; HYPOXIA; IL13RA1 GENE; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; LUCIFERASE ASSAY; MUC1 GENE; NNMT GENE; PATHOGENESIS; PLA2G2A GENE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RESPIRATORY TRACT DISEASE; RESPIRATORY TRACT INFLAMMATION; RNA SEQUENCE; SOD2 GENE; UPREGULATION; VEGFA GENE; WESTERN BLOTTING; WWC1 GENE; CYTOLOGY; DNA MICROARRAY; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYSTEM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; TRACHEA;

ASTHMA; BIOMARKERS; BLOTTING, WESTERN; CELL PROLIFERATION; GENE EXPRESSION PROFILING; HUMANS; INTERLEUKIN-6; MUSCLE, SMOOTH; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYSTEM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRACHEA;

EID: 84937421626     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00288.2014     Document Type: Article

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