The apelinergic system in the developing lung: Expression and signaling

Peptides

Volumn 32, Issue 12, 2011, Pages 2474-2483

  Piairo, Paulina ^a,b   Moura, Rute S ^a,b   Nogueira Silva, Cristina ^a,b,c   Correia Pinto, Jorge ^a,b,c  

^a UNIVERSITY OF MINHO   (Portugal)

^b UNIVERSITY OF MINHO   (Portugal)

^c HOSPITAL DE BRAGA   (Portugal)

Author keywords

Apelin; APJ; Lung development; MAP kinases

Indexed keywords

APELIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; FETUS; GESTATIONAL AGE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; LUNG PARENCHYMA; MORPHOGENESIS; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AGE FACTORS; ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; EPITHELIAL CELLS; FEMALE; GESTATIONAL AGE; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG; MAP KINASE SIGNALING SYSTEM; MORPHOGENESIS; PHOSPHORYLATION; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; TISSUE CULTURE TECHNIQUES;

RATTUS;

EID: 82655168817     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2011.10.010     Document Type: Article

References (49)

1. B. Bai, J. Tang, H. Liu, J. Chen, Y. Li, and W. Song Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway Acta Biochim Biophys Sin 40 4 2008 311 318 (Pubitemid 351572112)
2. G. Barnes, A.G. Japp, and D.E. Newby Translational promise of apelin-APJ system Heart 96 2010 1011 1016
3. M.M. Bradford Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 1976 248 254
4. I. Castan-Laurell, C. Dray, C. Attané, T. Duparc, C. Knauf, and P. Valet Apelin, diabetes, and obesity Endocrine 40 1 2011 1 9
5. F. Ciruela, J.P. Vilardaga, and V. Fernández-Dueñas Lighting up multiprotein complexes: lessons from GPCR oligomerization Trends Biotechnol 28 8 2010 407 415
6. X. Cheng, X.S. Cheng, and C.C. Pang Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats Eur J Pharmacol 470 2003 171 175 (Pubitemid 36694473)
7. H.J. Chun, Z.A. Ali, Y. Kojima, R.K. Kundu, A.Y. Sheikh, and R. Agrawal Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis J Clin Invest 118 10 2008 3343 3354
8. M.H. Cobb MAP kinase pathways Prog Biophys Mol Biol 71 3-4 1999 479 500 (Pubitemid 29156313)
9. C.M. Cox, S.L. D'Agostino, M.K. Miller, R.L. Heimark, and P.A. Krieg Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo Dev Biol 296 1 2006 177 189 (Pubitemid 44061763)
10. M. De Falco, L. De Luca, N. Onori, I. Cavallotti, F. Artigiano, and V. Esposito Apelin expression in normal human tissues In Vivo 16 5 2002 333 336 (Pubitemid 35469035)
11. J. Drews Drug discovery: a historical perspective Science 287 2000 1960 1964 (Pubitemid 30158662)
12. I. Falcão-Pires, R. Ladeiras-Lopes, and A.F. Leite-Moreira The apelinergic system: a promising therapeutic target Expert Opin Ther Targets 14 5 2010 1 13
13. G. Földes, F. Horkay, I. Szokodi, O. Vuolteenaho, M. Ilves, and K.A. Lindstedt Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure Biochem Biophys Res Commun 308 3 2003 480 485 (Pubitemid 36945517)
14. L.R. Gao, N.K. Zhang, J. Bai, Q.A. Ding, Z.G. Wang, and Z.M. Zhu The apelin-APJ pathway exists in cardiomyogenic cells derived from mesenchymal stem cells in vitro and in vivo Cell Transplant 19 2010 949 958
15. F. Gobeil, A. Fortier, T. Zhu, M. Bossolasco, M. Leduc, and M. Grandbois G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigm Can J Physiol Pharmacol 84 3-4 2006 287 297 (Pubitemid 44481092)
16. J.P. Goetze, J.F. Rehfeld, J. Carlsen, R. Videbaek, C.B. Andersen, and S. Boesgaard Apelin: a new plasma marker of cardiopulmonary disease Regul Pept 133 1-3 2006 134 138 (Pubitemid 41820346)
17. Y. Habata, R. Fujii, M. Hosoya, S. Fukusumi, Y. Kawamata, and S. Hinuma Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum Biochim Biophys Acta 1452 1999 25 35 (Pubitemid 29486739)
18. M. Hosoya, Y. Kawamata, S. Fukusumi, R. Fujii, Y. Habata, and S. Hinuma Molecular and functional characteristics of APJ: tissue distribution of mRNA and interaction with the endogenous ligand apelin J Biol Chem 275 2000 21061 21067 (Pubitemid 30481796)
19. R.E. Kälin, M.P. Kretz, A.M. Meyer, A. Kispert, F.L. Heppner, and A.W. Brändli Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis Dev Biol 305 2007 599 614 (Pubitemid 46686624)
20. A. Kasai, N. Shintani, H. Kato, S. Matsuda, F. Gomi, and R. Haba Retardation of retinal vascular development in apelin-deficient mice Arterioscler Thromb Vasc Biol 28 2008 1717 1722
21. Y. Kawamata, Y. Habata, S. Fukusumi, M. Hosoya, R. Fujii, and S. Hinuma Molecular properties of apelin: tissue distribution and receptor binding Biochim Biophys Acta 1538 2001 162 171 (Pubitemid 32402239)
22. M.J. Kleinz, and A.P. Davenport Emerging roles of apelin in biology and medicine Pharmacol Ther 107 2 2005 198 211 (Pubitemid 40916219)
23. M.J. Kleinz, J.N. Skepper, and A.P. Davenport Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells Regul Pept 126 3 2005 233 240 (Pubitemid 40128188)
24. D.E. Kling, H.K. Lorenzo, A.M. Trbovich, T.B. Kinane, P.K. Donahoe, and J.J. Schnitzer Pre- and postnatal lung development, maturation, and plasticity: MEK-1/2 inhibition reduces branching morphogenesis and causes mesenchymal cell apoptosis in fetal rat lungs Am J Physiol Lung Cell Mol Physiol 282 2002 L370 L378
25. D.K. Lee, R. Cheng, T. Nguyen, T. Fan, A.P. Kariyawasam, and Y. Liu Characterization of apelin, the ligand for the APJ receptor J Neurochem 74 2000 34 41 (Pubitemid 30012752)
26. D.K. Lee, S.R. George, and B.F. O'Dowd Unravelling the roles of the apelin system: prospective therapeutic applications in heart failure and obesity Trends Pharmacol Sci 27 4 2006 190 194
27. D.K. Lee, A.J. Lanca, R. Cheng, T. Nguyen, X.D. Ji, and F. Gobeil Jr. Agonist-independent nuclear localization of the Apelin, angiotensin AT1, and bradykinin B2 receptors J Biol Chem 279 9 2004 7901 7908 (Pubitemid 38294677)
28. D.K. Lee, V.R. Saldivia, T. Nguyen, R. Cheng, S.R. George, and B.F. O'Dowd Modification of the terminal residue of apelin-13 antagonizes its hypotensive action Endocrinology 146 1 2005 231 236 (Pubitemid 40051744)
29. C. Liu, T. Su, F. Li, L. Li, X. Qin, and W. Pan PI3K/Akt signaling transduction pathway is involved in rat vascular smooth muscle cell proliferation induced by apelin-13 Acta Biochim Biophys Sin 42 6 2010 396 402
30. B. Masri, H. Lahlou, H. Mazarguil, B. Knibiehler, and Y. Audigier Apelin (65-77) activates extracellular signal-regulated kinases via a PTX-sensitive G protein Biochem Biophys Res Commun 290 1 2002 539 545 (Pubitemid 34694535)
31. B. Masri, N. Morin, M. Cornu, B. Knibiehler, and Y. Audigier Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells FASEB J 18 15 2004 1909 1911 (Pubitemid 39602280)
32. A.D. Medhurst, C.A. Jennings, M.J. Robbins, R.P. Davis, C. Ellis, and K.Y. Winborn Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin J Neurochem 84 5 2003 1162 1172 (Pubitemid 36330668)
33. G. Milligan G protein-coupled receptor dimerization: function and ligand pharmacology Mol Pharmacol 66 1 2004 1 7 (Pubitemid 38822080)
34. E.E. Morrisey, and B.L. Hogan Preparing for the first breath: genetic and cellular mechanisms in lung development Dev Cell 18 2010 8 23
35. S.R. Neves, P.T. Ram, and R. Iyengar G protein pathways Science 296 5573 2002 1636 1639 (Pubitemid 34579147)
36. Nogueira-Silva C, Carvalho-Dias E, Piairo P, Nunes S, Baptista MJ, Moura RS, et al. Local Fetal lung renin-angiotensin system as a target to treat congenital diaphragmatic hernia. Personal communication.
37. C. Nogueira-Silva, M. Santos, M.J. Baptista, R.S. Moura, and J. Correia-Pinto IL-6 is constitutively expressed during lung morphogenesis and enhances fetal lung explant branching Pediatr Res 60 2006 530 536 (Pubitemid 44627397)
38. B.F. O'Dowd, M. Heiber, A. Chan, H.H.Q. Heng, L.C. Tsui, and J.L. Kennedy A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11 Gene 136 1993 355 360 (Pubitemid 24049270)
39. R. Quazi, C. Palaniswamy, and W.H. Frishman The emerging role of apelin in cardiovascular disease and health Cardiol Ver 17 2009 283 286
40. A. Reaux, N. De Mota, I. Skultetyova, Z. Lenkei, S. El Messari, and K. Gallatz Physiological role of a novel neuropeptide, apelin, and its receptor in the rat brain J Neurochem 77 2001 1085 1096 (Pubitemid 32467063)
41. X. Rovira, J.P. Pin, and J. Giraldo The asymmetric/symmetric activation of GPCR dimers as a possible mechanistic rationale for multiple signalling pathways Trends Pharmacol Sci 31 1 2010 15 21
42. I.C. Scott, B. Masri, L.A. D'Amico, S.W. Jin, B. Jungblut, and A.M. Wehman The G protein-coupled receptor agtrl1b regulates early development of myocardial progenitors Dev Cell 12 3 2007 403 413
43. S.C. Sorli, S. Le Gonidec, B. Knibiehler, and Y. Audigier Apelin is a potent activator of tumour neoangiogenesis Oncogene 26 55 2007 7692 7699 (Pubitemid 350224216)
44. X. Sun, S. Iida, A. Yoshikawa, R. Senbonmatsu, K. Imanaka, and K. Maruyama Non-activated APJ suppresses the angiotensin II type 1 receptor, whereas apelin-activated APJ acts conversely Hypertens Res 34 6 2011 701 706
45. K. Tatemoto, M. Hosoya, Y. Habata, R. Fujii, T. Kakegawa, and M.X. Zou Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor Biochem Biophys Res Commun 251 1998 471 476 (Pubitemid 28505047)
46. K. Tatemoto, K. Takayama, M.X. Zou, I. Kumaki, W. Zhang, and K. Kumano The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism Regul Pept 99 2-3 2001 87 92 (Pubitemid 32522535)
47. Y.P. Visser, F.J. Walther, H. Laghmani el, A. Laarse, and G.T. Wagenaar Apelin attenuates hyperoxic lung and heart injury in neonatal rats Am J Respir Crit Care Med 182 10 2010 1239 1250
48. D. Warburton, M. Schwarz, D. Tefft, G. Flores-Delgado, K.D. Anderson, and W.V. Cardoso The molecular basis of lung morphogenesis Mech Dev 92 1 2000 55 81 (Pubitemid 30125962)
49. X.X. Zeng, T.P. Wilm, D.S. Sepich, and L. Solnica-Krezel Apelin and its receptor control heart field formation during zebrafish gastrulation Dev Cell 12 3 2007 391 402