Rb and FZR1/Cdh1 determine CDK4/6-cyclin D requirement in C. elegans and human cancer cells

Nature Communications

Volumn 6, Issue , 2015, Pages

  The, Inge ^a   Ruijtenberg, Suzan ^a   Bouchet, Benjamin P ^a   Cristobal, Alba ^b   Prinsen, Martine B W ^a   Van Mourik, Tim ^a   Koreth, John ^c   Xu, Huihong ^d   Heck, Albert J R ^b   Akhmanova, Anna ^a   Cuppen, Edwin ^e   Boxem, Mike ^a   Muñoz, Javier ^b,f   Van Den Heuvel, Sander ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e HUBRECHT INSTITUTE   (Netherlands)

^f INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; CYCLIN D; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; FIZZY RELATED PROTEIN; GLUTATHIONE TRANSFERASE ALPHA; LIN 35 PROTEIN; PALBOCICLIB; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; FZR1 PROTEIN, HUMAN; LIN-35 PROTEIN, C ELEGANS; MULTIPROTEIN COMPLEX; REPRESSOR PROTEIN;

CANCER; ENZYME ACTIVITY; INHIBITOR; NEMATODE; PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BREAST CANCER CELL LINE; CAENORHABDITIS ELEGANS; CANCER CELL LINE; CELL CYCLE ARREST; CELL DIVISION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; GENE SILENCING; HUMAN; HUMAN CELL; NONHUMAN; TRANSLATION REGULATION; ANIMAL; CELL CYCLE; DNA SEQUENCE; FLUORESCENCE MICROSCOPY; GENETICS; HEK293 CELL LINE; IMMUNOPRECIPITATION; MASS SPECTROMETRY; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TUMOR CELL LINE;

CAENORHABDITIS ELEGANS;

ANIMALS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CDH1 PROTEINS; CELL CYCLE; CELL LINE, TUMOR; CYCLIN D; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; SEQUENCE ANALYSIS, DNA;

EID: 84937256380     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6906     Document Type: Article

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