Cost-effective alternative to nano-encapsulation: Amorphous curcumin-chitosan nanoparticle complex exhibiting high payload and supersaturation generation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 96, Issue , 2015, Pages 1-10

  Nguyen, Minh Hiep ^a   Yu, Hong ^a   Kiew, Tie Yi ^a   Hadinoto, Kunn ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

Amorphous drug; Curcumin solubility; Drug polysaccharide complex; Nanomedicine

Indexed keywords

CHITOSAN NANOPARTICLE; CURCUMIN; HYDROXYPROPYLMETHYLCELLULOSE; NANOCARRIER; POLYSACCHARIDE; CHITOSAN; DRUG CARRIER; MICROCAPSULE; NANOPARTICLE;

A549 CELL LINE; ARTICLE; COLLOID; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CYTOTOXICITY; DRUG SOLUBILITY; IN VITRO STUDY; MOLECULAR STABILITY; NANOPHARMACEUTICS; PARTICLE SIZE; PH; PHYSICAL PARAMETERS; SUPERSATURATION; SURFACE CHARGE; BIOAVAILABILITY; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; EPITHELIUM CELL; HUMAN; MICROCAPSULE; PHARMACEUTICS; PROCEDURES; SCANNING ELECTRON MICROSCOPY; SOLUBILITY; SURFACE PROPERTY; TUMOR CELL LINE;

BIOLOGICAL AVAILABILITY; BIOPHARMACEUTICS; CAPSULES; CELL LINE, TUMOR; CELL SURVIVAL; CHITOSAN; CURCUMIN; DRUG CARRIERS; DRUG COMPOUNDING; DRUG LIBERATION; DRUG STABILITY; EPITHELIAL CELLS; HUMANS; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; PARTICLE SIZE; SOLUBILITY; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 84937216397     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.07.007     Document Type: Article

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