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Volumn 11, Issue 2, 2015, Pages 98-105

Role of fibroblast growth factor 21 (fgf21) in the regulation of statural growth

Author keywords

Bone growth; Catch up growth; FGF21; Growth; Nutrition; Short stature

Indexed keywords

BONE MORPHOGENETIC PROTEIN; COLLAGEN TYPE 10; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 18; FIBROBLAST GROWTH FACTOR 19; FIBROBLAST GROWTH FACTOR 21; FIBROBLAST GROWTH FACTOR 23; FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTOR 9; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 3; GLUCOCORTICOID; GROWTH HORMONE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; PARATHYROID HORMONE RELATED PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN TYROSINE KINASE; SEX HORMONE; SMALL INTERFERING RNA; SOMATOMEDIN; SOMATOMEDIN C; SONIC HEDGEHOG PROTEIN; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 2; THYROID HORMONE; TRANSFORMING GROWTH FACTOR BETA; TRIACYLGLYCEROL; UNINDEXED DRUG;

EID: 84937141169     PISSN: 15733963     EISSN: 18756336     Source Type: Journal    
DOI: 10.2174/1573396311666150702105152     Document Type: Article
Times cited : (8)

References (107)
  • 1
    • 77955814651 scopus 로고    scopus 로고
    • Hormone-like (endocrine) Fgfs: Their evolutionary history and roles in development, metabolism, and disease
    • Itoh N. Hormone-like (endocrine) Fgfs: their evolutionary history and roles in development, metabolism, and disease. Cell Tissue Res 2010; 342(1): 1-11.
    • (2010) Cell Tissue Res , vol.342 , Issue.1 , pp. 1-11
    • Itoh, N.1
  • 2
    • 34247565954 scopus 로고    scopus 로고
    • Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
    • Goetz R, Beenken A, Ibrahimi OA, et al. Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members. Mol Cell Biol 2007; 27(9): 3417-28.
    • (2007) Mol Cell Biol , vol.27 , Issue.9 , pp. 3417-3428
    • Goetz, R.1    Beenken, A.2    Ibrahimi, O.A.3
  • 3
    • 84857185764 scopus 로고    scopus 로고
    • Endocrine fibroblast growth factors 15/19 and 21: From feast to famine
    • Potthoff MJ, Kliewer SA, Mangelsdorf DJ. Endocrine fibroblast growth factors 15/19 and 21: from feast to famine. Genes Dev 2012; 26(4): 312-24.
    • (2012) Genes Dev , vol.26 , Issue.4 , pp. 312-324
    • Potthoff, M.J.1    Kliewer, S.A.2    Mangelsdorf, D.J.3
  • 4
    • 79953843347 scopus 로고    scopus 로고
    • The FGFR D3 domain determines receptor selectivity for fibroblast growth factor 21
    • Gupte J, Yang L, Wu X, et al. The FGFR D3 domain determines receptor selectivity for fibroblast growth factor 21. J Mol Biol 2011; 408(3): 491-502.
    • (2011) J Mol Biol , vol.408 , Issue.3 , pp. 491-502
    • Gupte, J.1    Yang, L.2    Wu, X.3
  • 5
    • 41649109108 scopus 로고    scopus 로고
    • BetaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c
    • Suzuki M, Uehara Y, Motomura-Matsuzaka K, et al. betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c. Mol Endocrinol 2008; 22(4): 1006-14.
    • (2008) Mol Endocrinol , vol.22 , Issue.4 , pp. 1006-1014
    • Suzuki, M.1    Uehara, Y.2    Motomura-Matsuzaka, K.3
  • 6
    • 34848869695 scopus 로고    scopus 로고
    • Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
    • Kurosu H, Choi M, Ogawa Y, et al. Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J Biol Chem 2007; 282(37): 26687-95.
    • (2007) J Biol Chem , vol.282 , Issue.37 , pp. 26687-26695
    • Kurosu, H.1    Choi, M.2    Ogawa, Y.3
  • 7
    • 57849155278 scopus 로고    scopus 로고
    • FGF21 N- and C-termini play different roles in receptor interaction and activation
    • Yie J, Hecht R, Patel J, et al. FGF21 N- and C-termini play different roles in receptor interaction and activation. FEBS Lett 2009; 583(1): 19-24.
    • (2009) FEBS Lett , vol.583 , Issue.1 , pp. 19-24
    • Yie, J.1    Hecht, R.2    Patel, J.3
  • 8
    • 0034333526 scopus 로고    scopus 로고
    • Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein
    • Ito S, Kinoshita S, Shiraishi N, et al. Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel Klotho family protein. Mech Dev 2000; 98(1-2): 115-9.
    • (2000) Mech Dev , vol.98 , Issue.1-2 , pp. 115-119
    • Ito, S.1    Kinoshita, S.2    Shiraishi, N.3
  • 9
    • 84864388774 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 (FGF21) inhibits chondrocyte function and growth hormone action directly at the growth plate
    • Wu S, Levenson A, Kharitonenkov A, De Luca F. Fibroblast growth factor 21 (FGF21) inhibits chondrocyte function and growth hormone action directly at the growth plate. J Biol Chem 2012; 287(31): 26060-7.
    • (2012) J Biol Chem , vol.287 , Issue.31 , pp. 26060-26067
    • Wu, S.1    Levenson, A.2    Kharitonenkov, A.3    De Luca, F.4
  • 10
    • 57349098220 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 corrects obesity in mice
    • Coskun T, Bina HA, Schneider MA, et al. Fibroblast growth factor 21 corrects obesity in mice. Endocrinology 2008; 149(12): 6018- 27.
    • (2008) Endocrinology , vol.149 , Issue.12
    • Coskun, T.1    Bina, H.A.2    Schneider, M.A.3
  • 12
    • 33846418834 scopus 로고    scopus 로고
    • The metabolic state of diabetic monkeys is regulated by fibroblast growth factor- 21
    • Kharitonenkov A, Wroblewski VJ, Koester A, et al. The metabolic state of diabetic monkeys is regulated by fibroblast growth factor- 21. Endocrinology 2007; 148(2): 774-81.
    • (2007) Endocrinology , vol.148 , Issue.2 , pp. 774-781
    • Kharitonenkov, A.1    Wroblewski, V.J.2    Koester, A.3
  • 13
    • 70350455732 scopus 로고    scopus 로고
    • Acute glucoselowering and insulin-sensitizing action of FGF21 in insulinresistant mouse models--association with liver and adipose tissue effects
    • Xu J, Stanislaus S, Chinookoswong N, et al. Acute glucoselowering and insulin-sensitizing action of FGF21 in insulinresistant mouse models--association with liver and adipose tissue effects. Am J Physiol Endocrinol Metab 2009; 297(5): E1105-14.
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , Issue.5 , pp. 1105-1114
    • Xu, J.1    Stanislaus, S.2    Chinookoswong, N.3
  • 14
    • 61649127208 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
    • Xu J, Lloyd DJ, Hale C, et al. Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice. Diabetes 2009; 58(1): 250-9.
    • (2009) Diabetes , vol.58 , Issue.1 , pp. 250-259
    • Xu, J.1    Lloyd, D.J.2    Hale, C.3
  • 15
    • 34249711964 scopus 로고    scopus 로고
    • Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states
    • Badman MK, Pissios P, Kennedy AR, Koukos G, Flier JS, Maratos-Flier E. Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states. Cell Metab 2007; 5(6): 426-37.
    • (2007) Cell Metab , vol.5 , Issue.6 , pp. 426-437
    • Badman, M.K.1    Pissios, P.2    Kennedy, A.R.3    Koukos, G.4    Flier, J.S.5    Maratos-Flier, E.6
  • 16
    • 34249686631 scopus 로고    scopus 로고
    • Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21
    • Inagaki T, Dutchak P, Zhao G, et al. Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21. Cell Metab 2007; 5(6): 415-25.
    • (2007) Cell Metab , vol.5 , Issue.6 , pp. 415-425
    • Inagaki, T.1    Dutchak, P.2    Zhao, G.3
  • 18
    • 0034666132 scopus 로고    scopus 로고
    • Defect in peroxisome proliferator-activated receptor alphainducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting
    • Hashimoto T, Cook WS, Qi C, Yeldandi AV, Reddy JK, Rao MS. Defect in peroxisome proliferator-activated receptor alphainducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting J Biol Chem. 2000; 275(37): 28918- 28.
    • (2000) J Biol Chem , vol.275 , Issue.37 , pp. 28918-28928
    • Hashimoto, T.1    Cook, W.S.2    Qi, C.3    Yeldandi, A.V.4    Reddy, J.K.5    Rao, M.S.6
  • 19
    • 0032699670 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting
    • Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W. Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. J Clin Invest 1999; 103(11): 1489-98.
    • (1999) J Clin Invest , vol.103 , Issue.11 , pp. 1489-1498
    • Kersten, S.1    Seydoux, J.2    Peters, J.M.3    Gonzalez, F.J.4    Desvergne, B.5    Wahli, W.6
  • 20
    • 0033594980 scopus 로고    scopus 로고
    • A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: The PPARalpha-null mouse as a model of fatty acid oxidation disorders
    • Leone TC, Weinheimer CJ, Kelly DP. A critical role for the peroxisome proliferator-activated receptor alpha (PPARalpha) in the cellular fasting response: the PPARalpha-null mouse as a model of fatty acid oxidation disorders. Proc Natl Acad Sci U S A 1999; 96(13): 7473-8.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.13 , pp. 7473-7478
    • Leone, T.C.1    Weinheimer, C.J.2    Kelly, D.P.3
  • 21
    • 77955474305 scopus 로고    scopus 로고
    • Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease
    • Dushay J, Chui PC, Gopalakrishnan GS, et al. Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease. Gastroenterology 2010; 139(2): 456-63.
    • (2010) Gastroenterology , vol.139 , Issue.2 , pp. 456-463
    • Dushay, J.1    Chui, P.C.2    Gopalakrishnan, G.S.3
  • 22
    • 79960564639 scopus 로고    scopus 로고
    • Serum FGF21 levels are increased in newly diagnosed type 2 diabetes with nonalcoholic fatty liver disease and associated with hsCRP levels independently
    • Li X, Fan X, Ren F, et al. Serum FGF21 levels are increased in newly diagnosed type 2 diabetes with nonalcoholic fatty liver disease and associated with hsCRP levels independently. Diabetes Res Clin Pract. 2011; 93(1): 10-6.
    • (2011) Diabetes Res Clin Pract , vol.93 , Issue.1 , pp. 10-16
    • Li, X.1    Fan, X.2    Ren, F.3
  • 23
    • 77956519052 scopus 로고    scopus 로고
    • Increased serum FGF21 levels in patients with nonalcoholic fatty liver disease
    • Yilmaz Y, Eren F, Yonal O, et al. Increased serum FGF21 levels in patients with nonalcoholic fatty liver disease. Eur J Clin Invest 2010; 40(10): 887-92.
    • (2010) Eur J Clin Invest , vol.40 , Issue.10 , pp. 887-892
    • Yilmaz, Y.1    Eren, F.2    Yonal, O.3
  • 24
    • 54549118063 scopus 로고    scopus 로고
    • Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus
    • Chen WW, Li L, Yang GY, et al. Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes 2008; 116(1): 65- 8.
    • (2008) Exp Clin Endocrinol Diabetes , vol.116 , Issue.1
    • Chen, W.W.1    Li, L.2    Yang, G.Y.3
  • 25
    • 68149091653 scopus 로고    scopus 로고
    • Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance
    • Chavez AO, Molina-Carrion M, Abdul-Ghani MA, Folli F, Defronzo RA, Tripathy D. Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance. Diabetes Care 2009; 32(8): 1542-6.
    • (2009) Diabetes Care , vol.32 , Issue.8 , pp. 1542-1546
    • Chavez, A.O.1    Molina-Carrion, M.2    Abdul-Ghani, M.A.3    Folli, F.4    Defronzo, R.A.5    Tripathy, D.6
  • 26
    • 63849189712 scopus 로고    scopus 로고
    • Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity
    • Mraz M, Bartlova M, Lacinova Z, et al. Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity. Clin Endocrinol (Oxf) 2009; 71(3): 369-75.
    • (2009) Clin Endocrinol (Oxf) , vol.71 , Issue.3 , pp. 369-375
    • Mraz, M.1    Bartlova, M.2    Lacinova, Z.3
  • 27
    • 77956276954 scopus 로고    scopus 로고
    • Daily physical activity, fasting glucose, uric acid, and body mass index are independent factors associated with serum fibroblast growth factor 21 levels
    • Cuevas-Ramos D, Almeda-Valdes P, Gomez-Perez FJ, et al. Daily physical activity, fasting glucose, uric acid, and body mass index are independent factors associated with serum fibroblast growth factor 21 levels. Eur J Endocrinol 2010; 163(3): 469-77.
    • (2010) Eur J Endocrinol , vol.163 , Issue.3 , pp. 469-477
    • Cuevas-Ramos, D.1    Almeda-Valdes, P.2    Gomez-Perez, F.J.3
  • 28
    • 77950546742 scopus 로고    scopus 로고
    • Evaluation of concentrations of FGF-21 - a new adipocytokine in type 2 diabetes
    • Matuszek B, Lenart-Lipinska M, Duma D, Solski J, Nowakowski A. Evaluation of concentrations of FGF-21 - a new adipocytokine in type 2 diabetes. Endokrynol Pol 2010; 61(1): 50-4.
    • (2010) Endokrynol Pol , vol.61 , Issue.1 , pp. 50-54
    • Matuszek, B.1    Lenart-Lipinska, M.2    Duma, D.3    Solski, J.4    Nowakowski, A.5
  • 29
    • 77957359658 scopus 로고    scopus 로고
    • Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride
    • Li H, Fang Q, Gao F, et al. Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride. J Hepatol 2010; 53(5): 934-40.
    • (2010) J Hepatol , vol.53 , Issue.5 , pp. 934-940
    • Li, H.1    Fang, Q.2    Gao, F.3
  • 30
    • 48349146527 scopus 로고    scopus 로고
    • Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
    • Zhang X, Yeung DC, Karpisek M, et al. Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans. Diabetes 2008; 57(5): 1246-53.
    • (2008) Diabetes , vol.57 , Issue.5 , pp. 1246-1253
    • Zhang, X.1    Yeung, D.C.2    Karpisek, M.3
  • 31
    • 70350443243 scopus 로고    scopus 로고
    • A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss
    • Badman MK, Kennedy AR, Adams AC, Pissios P, Maratos-Flier E. A very low carbohydrate ketogenic diet improves glucose tolerance in ob/ob mice independently of weight loss. Am J Physiol Endocrinol Metab 2009; 297(5): E1197-204.
    • (2009) Am J Physiol Endocrinol Metab , vol.297 , Issue.5 , pp. 1197-1204
    • Badman, M.K.1    Kennedy, A.R.2    Adams, A.C.3    Pissios, P.4    Maratos-Flier, E.5
  • 32
    • 78049297991 scopus 로고    scopus 로고
    • Obesity is a fibroblast growth factor 21 (FGF21)-resistant state
    • Fisher FM, Chui PC, Antonellis PJ, et al. Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes 2010; 59(11): 2781-9.
    • (2010) Diabetes , vol.59 , Issue.11 , pp. 2781-2789
    • Fisher, F.M.1    Chui, P.C.2    Antonellis, P.J.3
  • 33
    • 47949111205 scopus 로고    scopus 로고
    • Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states
    • Muise ES, Azzolina B, Kuo DW, et al. Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor gamma and altered metabolic states. Mol Pharmacol 2008; 74(2): 403-12.
    • (2008) Mol Pharmacol , vol.74 , Issue.2 , pp. 403-412
    • Muise, E.S.1    Azzolina, B.2    Kuo, D.W.3
  • 34
    • 0015057014 scopus 로고
    • Cell population kinetics of bone growth: The first ten years of autoradiographic studies with tritiated thymidine
    • Kember NF. Cell population kinetics of bone growth: the first ten years of autoradiographic studies with tritiated thymidine. Clin Orthop Relat Res 1971; 76: 213-30.
    • (1971) Clin Orthop Relat Res , vol.76 , pp. 213-230
    • Kember, N.F.1
  • 35
    • 0028067659 scopus 로고
    • Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes
    • Hunziker EB. Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes. Microsc Res Tech 1994; 28(6): 505-19.
    • (1994) Microsc Res Tech , vol.28 , Issue.6 , pp. 505-519
    • Hunziker, E.B.1
  • 36
    • 0024361393 scopus 로고
    • Cellular turnover at the chondro-osseous junction of growth plate cartilage: Analysis by serial sections at the light microscopical level
    • Farnum CE, Wilsman NJ. Cellular turnover at the chondro-osseous junction of growth plate cartilage: analysis by serial sections at the light microscopical level. J Orthop Res 1989; 7(5): 654-66.
    • (1989) J Orthop Res , vol.7 , Issue.5 , pp. 654-666
    • Farnum, C.E.1    Wilsman, N.J.2
  • 37
    • 0029805072 scopus 로고    scopus 로고
    • Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene
    • Woods KA, Camacho-Hubner C, Savage MO, Clark AJ. Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene. N Engl J Med 1996; 335(18): 1363-7.
    • (1996) N Engl J Med , vol.335 , Issue.18 , pp. 1363-1367
    • Woods, K.A.1    Camacho-Hubner, C.2    Savage, M.O.3    Clark, A.J.4
  • 38
    • 0344874656 scopus 로고    scopus 로고
    • IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation
    • Abuzzahab MJ, Schneider A, Goddard A, et al. IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation. N Engl J Med 2003; 349(23): 2211-22.
    • (2003) N Engl J Med , vol.349 , Issue.23 , pp. 2211-2222
    • Abuzzahab, M.J.1    Schneider, A.2    Goddard, A.3
  • 39
    • 33644653308 scopus 로고    scopus 로고
    • Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature
    • Pantel J, Legendre M, Cabrol S, et al. Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature. J Clin Invest 2006; 116(3): 760-8.
    • (2006) J Clin Invest , vol.116 , Issue.3 , pp. 760-768
    • Pantel, J.1    Legendre, M.2    Cabrol, S.3
  • 40
    • 0028260333 scopus 로고
    • Growth hormone (GH) insensitivity due to primary GH receptor deficiency
    • Rosenfeld RG, Rosenbloom AL, Guevara-Aguirre J. Growth hormone (GH) insensitivity due to primary GH receptor deficiency. Endocr Rev 1994; 15(3): 369-90.
    • (1994) Endocr Rev , vol.15 , Issue.3 , pp. 369-390
    • Rosenfeld, R.G.1    Rosenbloom, A.L.2    Guevara-Aguirre, J.3
  • 41
    • 85047682715 scopus 로고    scopus 로고
    • Minireview: Tissue-specific versus generalized gene targeting of the igf1 and igf1r genes and their roles in insulin-like growth factor physiology
    • Butler AA, LeRoith D. Minireview: tissue-specific versus generalized gene targeting of the igf1 and igf1r genes and their roles in insulin-like growth factor physiology. Endocrinology 2001; 142(5): 1685-8.
    • (2001) Endocrinology , vol.142 , Issue.5 , pp. 1685-1688
    • Butler, A.A.1    LeRoith, D.2
  • 42
    • 0036740049 scopus 로고    scopus 로고
    • Circulating levels of IGF-1 directly regulate bone growth and density
    • Yakar S, Rosen CJ, Beamer WG, et al. Circulating levels of IGF-1 directly regulate bone growth and density. J Clin Invest 2002; 110(6): 771-81.
    • (2002) J Clin Invest , vol.110 , Issue.6 , pp. 771-781
    • Yakar, S.1    Rosen, C.J.2    Beamer, W.G.3
  • 43
    • 0031015949 scopus 로고    scopus 로고
    • Two-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: Comparison of two dosage levels and to GH-treated GH deficiency
    • Guevara-Aguirre J, Rosenbloom AL, Vasconez O, et al. Two-year treatment of growth hormone (GH) receptor deficiency with recombinant insulin-like growth factor I in 22 children: comparison of two dosage levels and to GH-treated GH deficiency. J Clin Endocrinol Metab 1997; 82(2): 629-33.
    • (1997) J Clin Endocrinol Metab , vol.82 , Issue.2 , pp. 629-633
    • Guevara-Aguirre, J.1    Rosenbloom, A.L.2    Vasconez, O.3
  • 44
    • 0033756507 scopus 로고    scopus 로고
    • Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5
    • Sims NA, Clement-Lacroix P, Da Ponte F, et al. Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5. J Clin Invest 2000; 106(9): 1095-103.
    • (2000) J Clin Invest , vol.106 , Issue.9 , pp. 1095-1103
    • Sims, N.A.1    Clement-Lacroix, P.2    Da Ponte, F.3
  • 45
    • 0023878410 scopus 로고
    • Regulation of insulin-like growth factor messenger ribonucleic acid in rat growth plate by growth hormone
    • Isgaard J, Moller C, Isaksson OG, Nilsson A, Mathews LS, Norstedt G. Regulation of insulin-like growth factor messenger ribonucleic acid in rat growth plate by growth hormone. Endocrinology 1988; 122(4): 1515-20.
    • (1988) Endocrinology , vol.122 , Issue.4 , pp. 1515-1520
    • Isgaard, J.1    Moller, C.2    Isaksson, O.G.3    Nilsson, A.4    Mathews, L.S.5    Norstedt, G.6
  • 46
    • 0023024908 scopus 로고
    • Evidence suggesting that the direct growth-promoting effect of growth hormone on cartilage in vivo is mediated by local production of somatomedin
    • Schlechter NL, Russell SM, Spencer EM, Nicoll CS. Evidence suggesting that the direct growth-promoting effect of growth hormone on cartilage in vivo is mediated by local production of somatomedin. Proc Natl Acad Sci U S A 1986; 83(20): 7932-4.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , Issue.20 , pp. 7932-7934
    • Schlechter, N.L.1    Russell, S.M.2    Spencer, E.M.3    Nicoll, C.S.4
  • 47
    • 0034770288 scopus 로고    scopus 로고
    • Catch-up growth is associated with delayed senescence of the growth plate in rabbits
    • Gafni RI, Weise M, Robrecht DT, et al. Catch-up growth is associated with delayed senescence of the growth plate in rabbits. Pediatr Res 2001; 50(5): 618-23.
    • (2001) Pediatr Res , vol.50 , Issue.5 , pp. 618-623
    • Gafni, R.I.1    Weise, M.2    Robrecht, D.T.3
  • 48
    • 0033990306 scopus 로고    scopus 로고
    • Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone
    • Silvestrini G, Ballanti P, Patacchioli FR, et al. Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone. Bone 2000; 26(1): 33-42.
    • (2000) Bone , vol.26 , Issue.1 , pp. 33-42
    • Silvestrini, G.1    Ballanti, P.2    Patacchioli, F.R.3
  • 49
    • 84995856149 scopus 로고
    • Suppressed spontaneous and stimulated growth hormone secretion in patients with Cushing's disease before and after surgical cure
    • Magiakou MA, Mastorakos G, Gomez MT, Rose SR, Chrousos GP. Suppressed spontaneous and stimulated growth hormone secretion in patients with Cushing's disease before and after surgical cure. J Clin Endocrinol Metab 1994; 78(1): 131-7.
    • (1994) J Clin Endocrinol Metab , vol.78 , Issue.1 , pp. 131-137
    • Magiakou, M.A.1    Mastorakos, G.2    Gomez, M.T.3    Rose, S.R.4    Chrousos, G.P.5
  • 50
    • 0028816712 scopus 로고
    • Growth and the growth hormone axis in prepubertal children with asthma
    • Crowley S, Hindmarsh PC, Matthews DR, Brook CG. Growth and the growth hormone axis in prepubertal children with asthma J Pediatr. 1995; 126(2): 297-303.
    • (1995) J Pediatr , vol.126 , Issue.2 , pp. 297-303
    • Crowley, S.1    Hindmarsh, P.C.2    Matthews, D.R.3    Brook, C.G.4
  • 52
    • 0024500683 scopus 로고
    • Congenital hypothyroidism: Decreased growth velocity in the first weeks of life
    • Leger J, Czernichow P. Congenital hypothyroidism: decreased growth velocity in the first weeks of life. Biol Neonate 1989; 55(4- 5): 218-23.
    • (1989) Biol Neonate , vol.55 , Issue.4-5 , pp. 218-223
    • Leger, J.1    Czernichow, P.2
  • 53
    • 0033752854 scopus 로고    scopus 로고
    • Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation
    • Robson H, Siebler T, Stevens DA, Shalet SM, Williams GR. Thyroid hormone acts directly on growth plate chondrocytes to promote hypertrophic differentiation and inhibit clonal expansion and cell proliferation. Endocrinology 2000; 141(10): 3887-97.
    • (2000) Endocrinology , vol.141 , Issue.10 , pp. 3887-3897
    • Robson, H.1    Siebler, T.2    Stevens, D.A.3    Shalet, S.M.4    Williams, G.R.5
  • 54
    • 0034768522 scopus 로고    scopus 로고
    • GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor alpha 1-/- beta-/- mice
    • Kindblom JM, Gothe S, Forrest D, Tornell J, Vennstrom B, Ohlsson C. GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor alpha 1-/- beta-/- mice. J Endocrinol 2001; 171(1): 15-22.
    • (2001) J Endocrinol , vol.171 , Issue.1 , pp. 15-22
    • Kindblom, J.M.1    Gothe, S.2    Forrest, D.3    Tornell, J.4    Vennstrom, B.5    Ohlsson, C.6
  • 55
    • 0022529328 scopus 로고
    • Pubertal growth in patients with androgen insensitivity: Indirect evidence for the importance of estrogens in pubertal growth of girls
    • Zachmann M, Prader A, Sobel EH, et al. Pubertal growth in patients with androgen insensitivity: indirect evidence for the importance of estrogens in pubertal growth of girls. J Pediatr 1986; 108(5 Pt 1): 694-7.
    • (1986) J Pediatr , vol.108 , Issue.5 , pp. 694-697
    • Zachmann, M.1    Prader, A.2    Sobel, E.H.3
  • 56
    • 0034504525 scopus 로고    scopus 로고
    • Estrogen, bone, growth and sex: A sea change in conventional wisdom
    • Grumbach MM. Estrogen, bone, growth and sex: a sea change in conventional wisdom. J Pediatr Endocrinol Metab 2000; 13 Suppl 6: 1439-55.
    • (2000) J Pediatr Endocrinol Metab , vol.13 , pp. 1439-1455
    • Grumbach, M.M.1
  • 57
    • 0028143234 scopus 로고
    • Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
    • Smith EP, Boyd J, Frank GR, et al. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 1994; 331(16): 1056-61.
    • (1994) N Engl J Med , vol.331 , Issue.16 , pp. 1056-1061
    • Smith, E.P.1    Boyd, J.2    Frank, G.R.3
  • 58
    • 0031120087 scopus 로고    scopus 로고
    • The role of estrogen in bone growth and maturation during childhood and adolescence
    • Cutler GB, Jr. The role of estrogen in bone growth and maturation during childhood and adolescence. J Steroid Biochem Mol Biol 1997; 61(3-6): 141-4.
    • (1997) J Steroid Biochem Mol Biol , vol.61 , Issue.3-6 , pp. 141-144
    • Cutler, G.B.1
  • 59
    • 0038476031 scopus 로고    scopus 로고
    • Localization of estrogen receptors-alpha and -beta and androgen receptor in the human growth plate at different pubertal stages
    • Nilsson O, Chrysis D, Pajulo O, et al. Localization of estrogen receptors-alpha and -beta and androgen receptor in the human growth plate at different pubertal stages. J Endocrinol 2003; 177(2): 319-26.
    • (2003) J Endocrinol , vol.177 , Issue.2 , pp. 319-326
    • Nilsson, O.1    Chrysis, D.2    Pajulo, O.3
  • 60
    • 0020713125 scopus 로고
    • Sites of action of testosterone and estradiol on longitudinal bone growth
    • Jansson JO, Eden S, Isaksson O. Sites of action of testosterone and estradiol on longitudinal bone growth. Am J Physiol 1983; 244(2): E135-40.
    • (1983) Am J Physiol , vol.244 , Issue.2 , pp. 135-140
    • Jansson, J.O.1    Eden, S.2    Isaksson, O.3
  • 63
    • 0027417528 scopus 로고
    • Androgen-stimulated pubertal growth: The effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty
    • Keenan BS, Richards GE, Ponder SW, Dallas JS, Nagamani M, Smith ER. Androgen-stimulated pubertal growth: the effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty. J Clin Endocrinol Metab 1993; 76(4): 996-1001.
    • (1993) J Clin Endocrinol Metab , vol.76 , Issue.4 , pp. 996-1001
    • Keenan, B.S.1    Richards, G.E.2    Ponder, S.W.3    Dallas, J.S.4    Nagamani, M.5    Smith, E.R.6
  • 64
    • 0242662055 scopus 로고    scopus 로고
    • 1,25(OH)2D3 and dihydrotestosterone interact to regulate proliferation and differentiation of epiphyseal chondrocytes
    • Krohn K, Haffner D, Hugel U, et al. 1,25(OH)2D3 and dihydrotestosterone interact to regulate proliferation and differentiation of epiphyseal chondrocytes. Calcif Tissue Int 2003; 73(4): 400-10.
    • (2003) Calcif Tissue Int , vol.73 , Issue.4 , pp. 400-410
    • Krohn, K.1    Haffner, D.2    Hugel, U.3
  • 65
    • 0032586720 scopus 로고    scopus 로고
    • Testosterone stimulates insulin-like growth factor-I and insulin-like growth factor-I-receptor gene expression in the mandibular condyle--a model of endochondral ossification
    • Maor G, Segev Y, Phillip M. Testosterone stimulates insulin-like growth factor-I and insulin-like growth factor-I-receptor gene expression in the mandibular condyle--a model of endochondral ossification. Endocrinology 1999; 140(4): 1901-10.
    • (1999) Endocrinology , vol.140 , Issue.4 , pp. 1901-1910
    • Maor, G.1    Segev, Y.2    Phillip, M.3
  • 68
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • Kronenberg HM. Developmental regulation of the growth plate. Nature 2003; 423(6937): 332-6.
    • (2003) Nature , vol.423 , Issue.6937 , pp. 332-336
    • Kronenberg, H.M.1
  • 69
    • 0028943780 scopus 로고
    • A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia
    • Schipani E, Kruse K, Juppner H. A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science 1995; 268(5207): 98-100.
    • (1995) Science , vol.268 , Issue.5207 , pp. 98-100
    • Schipani, E.1    Kruse, K.2    Juppner, H.3
  • 70
    • 0029849784 scopus 로고    scopus 로고
    • Constitutively activated receptors for parathyroid hormone and parathyroid hormone-related peptide in Jansen's metaphyseal chondrodysplasia
    • Schipani E, Langman CB, Parfitt AM, et al. Constitutively activated receptors for parathyroid hormone and parathyroid hormone-related peptide in Jansen's metaphyseal chondrodysplasia. N Engl J Med 1996; 335(10): 708-14.
    • (1996) N Engl J Med , vol.335 , Issue.10 , pp. 708-714
    • Schipani, E.1    Langman, C.B.2    Parfitt, A.M.3
  • 71
    • 0032128253 scopus 로고    scopus 로고
    • Absence of functional receptors for parathyroid hormone and parathyroid hormone-related peptide in Blomstrand chondrodysplasia
    • Jobert AS, Zhang P, Couvineau A, et al. Absence of functional receptors for parathyroid hormone and parathyroid hormone-related peptide in Blomstrand chondrodysplasia. J Clin Invest 1998; 102(1): 34-40.
    • (1998) J Clin Invest , vol.102 , Issue.1 , pp. 34-40
    • Jobert, A.S.1    Zhang, P.2    Couvineau, A.3
  • 72
    • 0031769483 scopus 로고    scopus 로고
    • A homozygous inactivating mutation in the parathyroid hormone/parathyroid hormone-related peptide receptor causing Blomstrand chondrodysplasia
    • Zhang P, Jobert AS, Couvineau A, Silve C. A homozygous inactivating mutation in the parathyroid hormone/parathyroid hormone-related peptide receptor causing Blomstrand chondrodysplasia. J Clin Endocrinol Metab 1998; 83(9): 3365-8.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.9 , pp. 3365-3368
    • Zhang, P.1    Jobert, A.S.2    Couvineau, A.3    Silve, C.4
  • 73
    • 33846566729 scopus 로고    scopus 로고
    • Fibroblast growth factor expression in the postnatal growth plate
    • Lazarus JE, Hegde A, Andrade AC, Nilsson O, Baron J. Fibroblast growth factor expression in the postnatal growth plate. Bone 2007; 40(3): 577-86.
    • (2007) Bone , vol.40 , Issue.3 , pp. 577-586
    • Lazarus, J.E.1    Hegde, A.2    Andrade, A.C.3    Nilsson, O.4    Baron, J.5
  • 74
    • 33847225869 scopus 로고    scopus 로고
    • Fibroblast growth factors 1, 2, 17, and 19 are the predominant FGF ligands expressed in human fetal growth plate cartilage
    • Krejci P, Krakow D, Mekikian PB, Wilcox WR. Fibroblast growth factors 1, 2, 17, and 19 are the predominant FGF ligands expressed in human fetal growth plate cartilage. Pediatr Res 2007; 61(3): 267- 72.
    • (2007) Pediatr Res , vol.61 , Issue.3
    • Krejci, P.1    Krakow, D.2    Mekikian, P.B.3    Wilcox, W.R.4
  • 75
    • 18144391965 scopus 로고    scopus 로고
    • FGF signaling in the developing endochondral skeleton
    • Ornitz DM. FGF signaling in the developing endochondral skeleton. Cytokine Growth Factor Rev 2005; 16(2): 205-13.
    • (2005) Cytokine Growth Factor Rev , vol.16 , Issue.2 , pp. 205-213
    • Ornitz, D.M.1
  • 77
    • 26944493862 scopus 로고    scopus 로고
    • Model for growth hormone receptor activation based on subunit rotation within a receptor dimer
    • Brown RJ, Adams JJ, Pelekanos RA, et al. Model for growth hormone receptor activation based on subunit rotation within a receptor dimer. Nat Struct Mol Biol 2005; 12(9): 814-21.
    • (2005) Nat Struct Mol Biol , vol.12 , Issue.9 , pp. 814-821
    • Brown, R.J.1    Adams, J.J.2    Pelekanos, R.A.3
  • 78
    • 44649148404 scopus 로고    scopus 로고
    • An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway
    • Rowlinson SW, Yoshizato H, Barclay JL, et al. An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway. Nat Cell Biol 2008; 10(6): 740-7.
    • (2008) Nat Cell Biol , vol.10 , Issue.6 , pp. 740-747
    • Rowlinson, S.W.1    Yoshizato, H.2    Barclay, J.L.3
  • 79
    • 34948897971 scopus 로고    scopus 로고
    • A ligand-receptor fusion of growth hormone forms a dimer and is a potent longacting agonist
    • Wilkinson IR, Ferrandis E, Artymiuk PJ, et al. A ligand-receptor fusion of growth hormone forms a dimer and is a potent longacting agonist. Nat Med 2007; 13(9): 1108-13.
    • (2007) Nat Med , vol.13 , Issue.9 , pp. 1108-1113
    • Wilkinson, I.R.1    Ferrandis, E.2    Artymiuk, P.J.3
  • 81
    • 0027179365 scopus 로고
    • Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase
    • Argetsinger LS, Campbell GS, Yang X, et al. Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase. Cell 1993; 74(2): 237-44.
    • (1993) Cell , vol.74 , Issue.2 , pp. 237-244
    • Argetsinger, L.S.1    Campbell, G.S.2    Yang, X.3
  • 82
    • 0034864712 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway regulates lysosomal degradation of the growth hormone receptor and its ligand
    • Van Kerkhof P, Strous GJ. The ubiquitin-proteasome pathway regulates lysosomal degradation of the growth hormone receptor and its ligand. Biochem. Soc. Trans 2001; 29: 488-493.
    • (2001) Biochem. Soc. Trans , vol.29 , pp. 488-493
    • Van Kerkhof, P.1    Strous, G.J.2
  • 83
    • 2542445326 scopus 로고    scopus 로고
    • Suppressors of cytokine signaling and regulation of GH action
    • Greenhalgh CJ, Alexander WS. Suppressors of cytokine signaling and regulation of GH action. Growth Horm IGF Res 2004; 14: 200- 206.
    • (2004) Growth Horm IGF Res , vol.14 , pp. 200-206
    • Greenhalgh, C.J.1    Alexander, W.S.2
  • 84
    • 21244433166 scopus 로고    scopus 로고
    • The IGF system: New developments relevant to pediatric practice
    • Rosenfeld RG. The IGF system: new developments relevant to pediatric practice. Endocr Dev 2005; 9: 1-10.
    • (2005) Endocr Dev , vol.9 , pp. 1-10
    • Rosenfeld, R.G.1
  • 85
    • 41549083742 scopus 로고    scopus 로고
    • Clinical relevance of systemic and local IGF-I: Lessons from animal models
    • LeRoith D. Clinical relevance of systemic and local IGF-I: lessons from animal models. Pediatr Endocrinol Rev 2008; 5 Suppl 2: 739- 43.
    • (2008) Pediatr Endocrinol Rev , vol.5 , pp. 739-743
    • LeRoith, D.1
  • 86
    • 0020039281 scopus 로고
    • Later growth of malnourished infants and children. Comparison with 'healthy' siblings and parents
    • Graham GG, Adrianzen B, Rabold J, Mellits ED. Later growth of malnourished infants and children. Comparison with 'healthy' siblings and parents. Am J Dis Child 1982; 136(4): 348-52.
    • (1982) Am J Dis Child , vol.136 , Issue.4 , pp. 348-352
    • Graham, G.G.1    Adrianzen, B.2    Rabold, J.3    Mellits, E.D.4
  • 87
    • 0028127946 scopus 로고
    • Nutritional regulation of the insulin-like growth factors
    • Thissen JP, Ketelslegers JM, Underwood LE. Nutritional regulation of the insulin-like growth factors. Endocr Rev 1994; 15(1): 80-101.
    • (1994) Endocr Rev , vol.15 , Issue.1 , pp. 80-101
    • Thissen, J.P.1    Ketelslegers, J.M.2    Underwood, L.E.3
  • 88
    • 0014215229 scopus 로고
    • Growth hormone and protein-calorie malnutrition. Impaired suppression during induced hyperglycaemia
    • Pimstone B, Barbezat G, Hansen JD, Murray P. Growth hormone and protein-calorie malnutrition. Impaired suppression during induced hyperglycaemia. Lancet 1967; 2(7530): 1333-4.
    • (1967) Lancet , vol.2 , Issue.7530 , pp. 1333-1334
    • Pimstone, B.1    Barbezat, G.2    Hansen, J.D.3    Murray, P.4
  • 89
    • 0025881398 scopus 로고
    • Differential regulation of the insulin-like growth factors (IGF-I and -II) and IGF binding proteins during malnutrition in the neonatal rat
    • Donovan SM, Atilano LC, Hintz RL, Wilson DM, Rosenfeld RG. Differential regulation of the insulin-like growth factors (IGF-I and -II) and IGF binding proteins during malnutrition in the neonatal rat. Endocrinology 1991; 129(1): 149-57.
    • (1991) Endocrinology , vol.129 , Issue.1 , pp. 149-157
    • Donovan, S.M.1    Atilano, L.C.2    Hintz, R.L.3    Wilson, D.M.4    Rosenfeld, R.G.5
  • 90
    • 0031195814 scopus 로고    scopus 로고
    • Resistance to growth hormone in children with chronic liver disease
    • Bucuvalas JC, Horn JA, Chernausek SD. Resistance to growth hormone in children with chronic liver disease. Pediatr Transplant 1997; 1(1): 73-9.
    • (1997) Pediatr Transplant , vol.1 , Issue.1 , pp. 73-79
    • Bucuvalas, J.C.1    Horn, J.A.2    Chernausek, S.D.3
  • 91
    • 0032616146 scopus 로고    scopus 로고
    • Determinants of circulating insulinlike growth factor-I
    • Hall K, Hilding A, Thoren M. Determinants of circulating insulinlike growth factor-I. J Endocrinol Invest 1999; 22(5 Suppl): 48-57.
    • (1999) J Endocrinol Invest , vol.22 , Issue.5 , pp. 48-57
    • Hall, K.1    Hilding, A.2    Thoren, M.3
  • 93
    • 0020543020 scopus 로고
    • Fear of obesity. Impaired suppression during induced hyperglycaemia. A cause of short stature and delayed puberty
    • Pugliese MT, Lifshitz F, Grad G, Fort P, Marks-Katz M. Fear of obesity. A cause of short stature and delayed puberty. N Engl J Med 1983; 309(9): 513-8.
    • (1983) N Engl J Med , vol.309 , Issue.9 , pp. 513-518
    • Pugliese, M.T.1    Lifshitz, F.2    Grad, G.3    Fort, P.4    Marks-Katz, M.5
  • 94
    • 80555145067 scopus 로고    scopus 로고
    • Anorexia nervosa: A unified neurological perspective
    • Hasan TF, Hasan H. Anorexia nervosa: a unified neurological perspective. Int J Med Sci 2011; 8(8): 679-703.
    • (2011) Int J Med Sci , vol.8 , Issue.8 , pp. 679-703
    • Hasan, T.F.1    Hasan, H.2
  • 96
    • 0020415922 scopus 로고
    • Growth hormone receptors in rat liver membranes: Effects of fasting and refeeding, and correlation with plasma somatomedin activity
    • Postel-Vinay MC, Cohen-Tanugi E, Charrier J. Growth hormone receptors in rat liver membranes: effects of fasting and refeeding, and correlation with plasma somatomedin activity. Mol Cell Endocrinol 1982; 28: 657-669.
    • (1982) Mol Cell Endocrinol , vol.28 , pp. 657-669
    • Postel-Vinay, M.C.1    Cohen-Tanugi, E.2    Charrier, J.3
  • 97
    • 0018929433 scopus 로고
    • Somatogenic receptors of rat liver: Regulation by insulin
    • Baxter RC, Bryson JM, Turtle JR. Somatogenic receptors of rat liver: regulation by insulin. Endocrinology 1980; 107: 1176-1181.
    • (1980) Endocrinology , vol.107 , pp. 1176-1181
    • Baxter, R.C.1    Bryson, J.M.2    Turtle, J.R.3
  • 99
    • 84860341324 scopus 로고    scopus 로고
    • Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in mice
    • Kubicky RA, Wu S, Kharitonenkov A, De Luca F. Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in mice. Endocrinology 2012; 153(5): 2287- 95.
    • (2012) Endocrinology , vol.153 , Issue.5
    • Kubicky, R.A.1    Wu, S.2    Kharitonenkov, A.3    De Luca, F.4
  • 100
    • 72849130864 scopus 로고    scopus 로고
    • LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice
    • Touvier T, Conte-Auriol F, Briand O, et al. LEPROT and LEPROTL1 cooperatively decrease hepatic growth hormone action in mice. J Clin Invest 2009; 119(12): 3830-8.
    • (2009) J Clin Invest , vol.119 , Issue.12 , pp. 3830-3838
    • Touvier, T.1    Conte-Auriol, F.2    Briand, O.3
  • 101
    • 84884580553 scopus 로고    scopus 로고
    • Increased Expression of Fibroblast Growth Factor 21 (FGF21) during Chronic Undernutrition Causes Growth Hormone Insensitivity in Chondrocytes by Inducing Leptin Receptor Overlapping Transcript (LEPROT) and Leptin Receptor Overlapping Transcriptlike 1 (LEPROTL1) Expression
    • Wu S, Grunwald T, Khartinonenkov A, Dam J, Jockers R, De Luca F. Increased Expression of Fibroblast Growth Factor 21 (FGF21) during Chronic Undernutrition Causes Growth Hormone Insensitivity in Chondrocytes by Inducing Leptin Receptor Overlapping Transcript (LEPROT) and Leptin Receptor Overlapping Transcriptlike 1 (LEPROTL1) Expression. J Biol Chem 2013; 288: 27375- 27383.
    • (2013) J Biol Chem , vol.288 , pp. 27375-27383
    • Wu, S.1    Grunwald, T.2    Khartinonenkov, A.3    Dam, J.4    Jockers, R.5    De Luca, F.6
  • 102
    • 33846067098 scopus 로고    scopus 로고
    • BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways
    • Yoon BS, Pogue R, Ovchinnikov DA, et al. BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development 2006; 133: 4667-4678
    • (2006) Development , vol.133 , pp. 4667-4678
    • Yoon, B.S.1    Pogue, R.2    Ovchinnikov, D.A.3
  • 103
    • 0036744820 scopus 로고    scopus 로고
    • Interaction of FGF, Ihh/PTHrP, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation
    • Minina E, Kreschel C, Naski MC, et al. Interaction of FGF, Ihh/PTHrP, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation. Dev Cell 2002; 3: 439-449.
    • (2002) Dev Cell , vol.3 , pp. 439-449
    • Minina, E.1    Kreschel, C.2    Naski, M.C.3
  • 104
    • 75149195216 scopus 로고    scopus 로고
    • Fibroblast growth factor-21 may mediate growth hormone resistance in anorexia nervosa
    • Fazeli PK, Misra M, Goldstein M, Miller KK, Klibanski A. Fibroblast growth factor-21 may mediate growth hormone resistance in anorexia nervosa. J Clin Endocrinol Metab 2010; 95(1): 369-74.
    • (2010) J Clin Endocrinol Metab , vol.95 , Issue.1 , pp. 369-374
    • Fazeli, P.K.1    Misra, M.2    Goldstein, M.3    Miller, K.K.4    Klibanski, A.5
  • 105
    • 79958810325 scopus 로고    scopus 로고
    • Serum FGF21 in boys with idiopathic short stature: Relationship to lipid profile, onset of puberty and growth
    • Hero M, Dunkel L, Vaaralahti K, Raivio T. Serum FGF21 in boys with idiopathic short stature: relationship to lipid profile, onset of puberty and growth. Clin Endocrinol (Oxf) 2011; 75(1): 141-2.
    • (2011) Clin Endocrinol (Oxf) , vol.75 , Issue.1 , pp. 141-142
    • Hero, M.1    Dunkel, L.2    Vaaralahti, K.3    Raivio, T.4
  • 106
    • 84912109442 scopus 로고    scopus 로고
    • Serum Fibroblast Growth Factor 21 Levels Are Inversely Associated with Growth Rates in Infancy
    • Mericq V, De Luca F, Hernandez MI, et al. Serum Fibroblast Growth Factor 21 Levels Are Inversely Associated with Growth Rates in Infancy. Horm Res Paediatr 2014; 82(5): 324-31.
    • (2014) Horm Res Paediatr , vol.82 , Issue.5 , pp. 324-331
    • Mericq, V.1    De Luca, F.2    Hernandez, M.I.3
  • 107
    • 84909993520 scopus 로고    scopus 로고
    • Elevated FGF21 Leads to Attenuated Postnatal Linear Growth in Preterm Infants Through GH Resistance in Chondrocytes
    • Guasti L, Silvennoinen S, Bulstrode NW, Ferretti P, Sankilampi U, Dunkel L. Elevated FGF21 Leads to Attenuated Postnatal Linear Growth in Preterm Infants Through GH Resistance in Chondrocytes. J Clin Endocrinol Metab 2014; 99(11): E2198-206.
    • (2014) J Clin Endocrinol Metab , vol.99 , Issue.11 , pp. 2198-2206
    • Guasti, L.1    Silvennoinen, S.2    Bulstrode, N.W.3    Ferretti, P.4    Sankilampi, U.5    Dunkel, L.6


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