Synthesis of chalcone analogues with increased antileishmanial activity

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 5, 2006, Pages 1538-1545

  Boeck, Paula ^a   Bandeira Falcão, Camila Alves ^c   Leal, Paulo César ^a   Yunes, Rosendo Augusto ^a   Filho, Valdir Cechinel ^b   Torres Santos, Eduardo Caio ^c   Rossi Bergmann, Bartira ^c  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSIDADE DO VALE DO ITAJAÍ   (Brazil)

^c FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Chalcone; Cutaneous leishmaniasis; Leishmania; Xanthoxyline

Indexed keywords

1 (2' HYDROXY 4',6' DIMETHOXYPHENYL) 3 (2 NAPHTHYL)PROP 2 EN 1 ONE; 2 [ 3 (2' HYDROXY 4',6' DIMETHOXYPHENYL) 3 OXOPROP 1 ENYL]BENZOIC ACID; 2 CHLORO 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 2 CHLORO 3' BROMO 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 2' HYDROXY 4'6' DIMETHOXYCHALCONE; 3 (2 FURYL) 1 (2' HYDROXY 4',6' DIMETHOXYPHENYL)PROP 2 EN 1 ONE; 3 NITRO 2' HYDROXY 4'6' DIMETHOXYCHALCONE; 3 NITRO 3' BROMO 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 3' BROMO 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 3,4 DICHLORO 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 3,4 METHYLENEDIOXY 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 4 BROMO 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 4 CHLORO 2' HYDROXY 4'6' DIMETHOXYCHALCONE; 4 FLUORO 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 4 METHOXY 2' HYDROXY 4'6'DIMETHOXYCHALCONE; 4 METHYL 2' HYDROXY 4',6' DIMETHOXYCHALCONE; 4 NITRO 2' HYDROXY 4'6' DIMETHOXYCHALCONE; CHALCONE DERIVATIVE; PENTAMIDINE; STIBOGLUCONATE SODIUM; UNCLASSIFIED DRUG;

AMASTIGOTE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG MEGADOSE; DRUG SELECTIVITY; DRUG SYNTHESIS; LEISHMANIASIS; NITROSYLATION; NONHUMAN; PROMASTIGOTE;

ACETOPHENONES; ANIMALS; ANTIPROTOZOAL AGENTS; CHALCONE; LEISHMANIA; LEISHMANIASIS; MICE; MICE, INBRED BALB C; MOLECULAR STRUCTURE; TIME FACTORS;

LEISHMANIA AMAZONENSIS;

EID: 31044435347     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.10.005     Document Type: Article

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