Anti-HIV-1 and cytotoxicity studies of piperidyl-thienyl chalcones and their 2-pyrazoline derivatives

Medicinal Chemistry Research

Volumn 21, Issue 11, 2012, Pages 3741-3749

  Rizvi, Syed Umar Farooq ^a   Siddiqui, Hamid Latif ^a   Johns, Melissa ^a   Detorio, Mervi ^b   Schinazi, Raymond F ^b  

^a UNIVERSITY OF THE PUNJAB   (Pakistan)

^b EMORY UNIVERSITY   (United States)

Author keywords

Acetylthiophenes; Anti HIV 1 activity; Chalcones; Cytotoxic activity; Pyrazolines

Indexed keywords

1 (3 BROMOTHIOPHEN 2 YL) 3 (4 PIPERIDIN 1 YLPHENYL)PROP 2 EN 1 ONE; 1 (3 CHLOROTHIOPHEN 2 YL) 3 (4 PIPERIDIN 1YLPHENYL)PROP 2 EN 1 ONE; 1 (3 METHYLTHIOPHEN 2 YL) 3 (4 PIPERIDIN 1 YLPHENYL)PROP 2 EN 1 ONE; 1 [4 (3 THIOPHEN 2 YL 4,5 DIHYDRO 1H PYRAZOL 5YL)PHENYL]PIPERIDINE; 1 [4 (3 THIOPHEN 3 YL 4,5 DIHYDRO 1H PYRAZOL 5YL)PHENYL]PIPERIDINE; 1 [4 [3 (2,5 DICHLOROTHIOPHEN 3 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; 1 [4 [3 (2,5 DIMETHYLTHIOPHEN 3 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; 1 [4 [3 (3 BROMOTHIOPHEN 2 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; 1 [4 [3 (3 CHLOROTHIOPHEN 2 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; 1 [4 [3 (3 METHYLTHIOPHEN 2 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; 1 [4 [3 (4 METHYLTHIOPHEN 2 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; 1 [4 [3 (5 BROMOTHIOPHEN 2 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; 1 [4 [3 (5 CHLOROTHIOPHEN 2 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; 1 [4 [3 (5 IODOTHIOPHEN 2 YL) 4,5 DIHYDRO 1H PYRAZOL 5YL]PHENYL]PIPERIDINE; 1 [4 [3 (5 METHYLTHIOPHEN 2 YL) 4,5 DIHYDRO 1H PYRAZOL 5 YL]PHENYL]PIPERIDINE; ANTIVIRUS AGENT; CHALCONE DERIVATIVE; PYRAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BIOASSAY; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; VERO CELL;

EID: 84871431072     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9912-x     Document Type: Article

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