Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs

Blood

Volumn 125, Issue 20, 2015, Pages 3202-3212

  Njock, Makon Sébastien ^a,b,c   Cheng, Henry S ^a,b,c   Dang, Lan T ^a,b,c   Nazari Jahantigh, Maliheh ^d   Lau, Andrew C ^a,b,c   Boudreau, Emilie ^a,b,c   Roufaiel, Mark ^a,b,c   Cybulsky, Myron I ^a,b,c   Schober, Andreas ^d,e   Fish, Jason E ^a,b,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HEART AND STROKE FOUNDATION OF CANADA   (Canada)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^e DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MICRORNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR; IRF5 PROTEIN, HUMAN; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELLULAR SECRETION; COCULTURE; CONTROLLED STUDY; EXOSOME; GENE TRANSFER; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; LEUKOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULITIS; CELL COMMUNICATION; CELL LINE; ENDOTHELIUM CELL; EXTRACELLULAR SPACE; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; MONOCYTE; SECRETORY VESICLE; SIGNAL TRANSDUCTION;

CELL COMMUNICATION; CELL LINE; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; EXTRACELLULAR SPACE; HUMANS; INFLAMMATION; INTERFERON REGULATORY FACTORS; LIPOPOLYSACCHARIDES; MICRORNAS; MONOCYTES; NF-KAPPA B; SECRETORY VESICLES; SIGNAL TRANSDUCTION;

EID: 84937129028     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-11-611046     Document Type: Article

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