-
1
-
-
47949096781
-
Cancer-related inflammation
-
10.1038/nature07205, 18650914
-
Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature 2008, 454:436-444. 10.1038/nature07205, 18650914.
-
(2008)
Nature
, vol.454
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
2
-
-
77953485565
-
Molecular pathways linking inflammation and cancer
-
10.2174/156652410791316968, 20455855
-
Mantovani A. Molecular pathways linking inflammation and cancer. Curr Mol Med 2010, 10:369-373. 10.2174/156652410791316968, 20455855.
-
(2010)
Curr Mol Med
, vol.10
, pp. 369-373
-
-
Mantovani, A.1
-
3
-
-
0031897632
-
NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses
-
10.1146/annurev.immunol.16.1.225, 9597130
-
Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998, 16:225-260. 10.1146/annurev.immunol.16.1.225, 9597130.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
4
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
10.1146/annurev.immunol.021908.132641, 19302050
-
Vallabhapurapu S, Karin M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol 2009, 27:693-733. 10.1146/annurev.immunol.021908.132641, 19302050.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
5
-
-
0023724778
-
I kappa B: a specific inhibitor of the NF-kappa B transcription factor
-
10.1126/science.3140380, 3140380
-
Baeuerle PA, Baltimore D. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 1988, 242:540-546. 10.1126/science.3140380, 3140380.
-
(1988)
Science
, vol.242
, pp. 540-546
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
6
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
10.1016/j.cell.2008.01.020, 18267068
-
Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008, 132:344-362. 10.1016/j.cell.2008.01.020, 18267068.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
7
-
-
0029874138
-
The NF-kappa B and I kappa B proteins: new discoveries and insights
-
10.1146/annurev.immunol.14.1.649, 8717528
-
Baldwin AS. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol 1996, 14:649-683. 10.1146/annurev.immunol.14.1.649, 8717528.
-
(1996)
Annu Rev Immunol
, vol.14
, pp. 649-683
-
-
Baldwin, A.S.1
-
8
-
-
34248217545
-
Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway
-
Cheng DS, Han W, Chen SM, Sherrill TP, Chont M, Park GY, Sheller JR, Polosukhin VV, Christman JW, Yull FE, Blackwell TS. Airway epithelium controls lung inflammation and injury through the NF-kappa B pathway. J Immunol 2007, 178:6504-6513.
-
(2007)
J Immunol
, vol.178
, pp. 6504-6513
-
-
Cheng, D.S.1
Han, W.2
Chen, S.M.3
Sherrill, T.P.4
Chont, M.5
Park, G.Y.6
Sheller, J.R.7
Polosukhin, V.V.8
Christman, J.W.9
Yull, F.E.10
Blackwell, T.S.11
-
9
-
-
79953064635
-
Inhibition of NF-kappaB activity in mammary epithelium increases tumor latency and decreases tumor burden
-
10.1038/onc.2010.521, 21076466
-
Connelly L, Barham W, Onishko HM, Sherrill T, Chodosh LA, Blackwell TS, Yull FE. Inhibition of NF-kappaB activity in mammary epithelium increases tumor latency and decreases tumor burden. Oncogene 2011, 30:1402-1412. 10.1038/onc.2010.521, 21076466.
-
(2011)
Oncogene
, vol.30
, pp. 1402-1412
-
-
Connelly, L.1
Barham, W.2
Onishko, H.M.3
Sherrill, T.4
Chodosh, L.A.5
Blackwell, T.S.6
Yull, F.E.7
-
10
-
-
73949129285
-
Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection
-
10.1002/jcp.21922, 2783968, 19746431
-
Connelly L, Barham W, Pigg R, Saint-Jean L, Sherrill T, Cheng DS, Chodosh LA, Blackwell TS, Yull FE. Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection. J Cell Physiol 2010, 222:73-81. 10.1002/jcp.21922, 2783968, 19746431.
-
(2010)
J Cell Physiol
, vol.222
, pp. 73-81
-
-
Connelly, L.1
Barham, W.2
Pigg, R.3
Saint-Jean, L.4
Sherrill, T.5
Cheng, D.S.6
Chodosh, L.A.7
Blackwell, T.S.8
Yull, F.E.9
-
11
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
10.1038/nrc1256, 14708027
-
Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004, 4:71-78. 10.1038/nrc1256, 14708027.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
12
-
-
68949114117
-
Tumor-associated macrophages: effectors of angiogenesis and tumor progression
-
Coffelt SB, Hughes R, Lewis CE. Tumor-associated macrophages: effectors of angiogenesis and tumor progression. Biochim Biophys Acta 2009, 1796:11-18.
-
(2009)
Biochim Biophys Acta
, vol.1796
, pp. 11-18
-
-
Coffelt, S.B.1
Hughes, R.2
Lewis, C.E.3
-
13
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
10.1158/0008-5472.CAN-05-4005, 16423985
-
Lewis CE, Pollard JW. Distinct role of macrophages in different tumor microenvironments. Cancer Res 2006, 66:605-612. 10.1158/0008-5472.CAN-05-4005, 16423985.
-
(2006)
Cancer Res
, vol.66
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
14
-
-
42149099408
-
Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms
-
Biswas SK, Sica A, Lewis CE. Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J Immunol 2008, 180:2011-2017.
-
(2008)
J Immunol
, vol.180
, pp. 2011-2017
-
-
Biswas, S.K.1
Sica, A.2
Lewis, C.E.3
-
15
-
-
40049088602
-
The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages
-
10.1016/j.critrevonc.2007.07.004, 17913510
-
Allavena P, Sica A, Solinas G, Porta C, Mantovani A. The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit Rev Oncol Hematol 2008, 66:1-9. 10.1016/j.critrevonc.2007.07.004, 17913510.
-
(2008)
Crit Rev Oncol Hematol
, vol.66
, pp. 1-9
-
-
Allavena, P.1
Sica, A.2
Solinas, G.3
Porta, C.4
Mantovani, A.5
-
16
-
-
33344460032
-
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation)
-
10.1182/blood-2005-01-0428, 16269622
-
Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A, Vincenzo B, Pasqualini F, Vago L, Nebuloni M, Mantovani A, Sica A. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation). Blood 2006, 107:2112-2122. 10.1182/blood-2005-01-0428, 16269622.
-
(2006)
Blood
, vol.107
, pp. 2112-2122
-
-
Biswas, S.K.1
Gangi, L.2
Paul, S.3
Schioppa, T.4
Saccani, A.5
Sironi, M.6
Bottazzi, B.7
Doni, A.8
Vincenzo, B.9
Pasqualini, F.10
Vago, L.11
Nebuloni, M.12
Mantovani, A.13
Sica, A.14
-
17
-
-
4043088499
-
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
10.1016/j.cell.2004.07.013, 15294155
-
Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, Egan LJ, Kagnoff MF, Karin M. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004, 118:285-296. 10.1016/j.cell.2004.07.013, 15294155.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
Park, J.M.4
Li, Z.W.5
Egan, L.J.6
Kagnoff, M.F.7
Karin, M.8
-
18
-
-
21244472975
-
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
-
10.1016/j.cell.2005.04.014, 15989949
-
Maeda S, Kamata H, Luo JL, Leffert H, Karin M. IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 2005, 121:977-990. 10.1016/j.cell.2005.04.014, 15989949.
-
(2005)
Cell
, vol.121
, pp. 977-990
-
-
Maeda, S.1
Kamata, H.2
Luo, J.L.3
Leffert, H.4
Karin, M.5
-
19
-
-
33645760428
-
Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype
-
Hagemann T, Wilson J, Burke F, Kulbe H, Li NF, Pluddemann A, Charles K, Gordon S, Balkwill FR. Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype. J Immunol 2006, 176:5023-5032.
-
(2006)
J Immunol
, vol.176
, pp. 5023-5032
-
-
Hagemann, T.1
Wilson, J.2
Burke, F.3
Kulbe, H.4
Li, N.F.5
Pluddemann, A.6
Charles, K.7
Gordon, S.8
Balkwill, F.R.9
-
20
-
-
23244451640
-
Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK
-
Hagemann T, Wilson J, Kulbe H, Li NF, Leinster DA, Charles K, Klemm F, Pukrop T, Binder C, Balkwill FR. Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK. J Immunol 2005, 175:1197-1205.
-
(2005)
J Immunol
, vol.175
, pp. 1197-1205
-
-
Hagemann, T.1
Wilson, J.2
Kulbe, H.3
Li, N.F.4
Leinster, D.A.5
Charles, K.6
Klemm, F.7
Pukrop, T.8
Binder, C.9
Balkwill, F.R.10
-
21
-
-
45149134605
-
"Re-educating" tumor-associated macrophages by targeting NF-kappaB
-
10.1084/jem.20080108, 2413024, 18490490
-
Hagemann T, Lawrence T, McNeish I, Charles KA, Kulbe H, Thompson RG, Robinson SC, Balkwill FR. "Re-educating" tumor-associated macrophages by targeting NF-kappaB. J Exp Med 2008, 205:1261-1268. 10.1084/jem.20080108, 2413024, 18490490.
-
(2008)
J Exp Med
, vol.205
, pp. 1261-1268
-
-
Hagemann, T.1
Lawrence, T.2
McNeish, I.3
Charles, K.A.4
Kulbe, H.5
Thompson, R.G.6
Robinson, S.C.7
Balkwill, F.R.8
-
22
-
-
57049187266
-
Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth
-
10.1007/s10585-008-9206-y, 2588650, 18787962
-
Martin MD, Fingleton B, Lynch CC, Wells S, McIntyre JO, Piston DW, Matrisian LM. Establishment and quantitative imaging of a 3D lung organotypic model of mammary tumor outgrowth. Clin Exp Metastasis 2008, 25:877-885. 10.1007/s10585-008-9206-y, 2588650, 18787962.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 877-885
-
-
Martin, M.D.1
Fingleton, B.2
Lynch, C.C.3
Wells, S.4
McIntyre, J.O.5
Piston, D.W.6
Matrisian, L.M.7
-
23
-
-
0037307026
-
A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse
-
10.1182/blood-2002-02-0569, 12393599
-
Sasmono RT, Oceandy D, Pollard JW, Tong W, Pavli P, Wainwright BJ, Ostrowski MC, Himes SR, Hume DA. A macrophage colony-stimulating factor receptor-green fluorescent protein transgene is expressed throughout the mononuclear phagocyte system of the mouse. Blood 2003, 101:1155-1163. 10.1182/blood-2002-02-0569, 12393599.
-
(2003)
Blood
, vol.101
, pp. 1155-1163
-
-
Sasmono, R.T.1
Oceandy, D.2
Pollard, J.W.3
Tong, W.4
Pavli, P.5
Wainwright, B.J.6
Ostrowski, M.C.7
Himes, S.R.8
Hume, D.A.9
-
24
-
-
0032923739
-
Generalized lacZ expression with the ROSA26 Cre reporter strain
-
10.1038/5007, 9916792
-
Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet 1999, 21:70-71. 10.1038/5007, 9916792.
-
(1999)
Nat Genet
, vol.21
, pp. 70-71
-
-
Soriano, P.1
-
25
-
-
35548932872
-
A global double-fluorescent Cre reporter mouse
-
10.1002/dvg.20335, 17868096
-
Muzumdar MD, Tasic B, Miyamichi K, Li L, Luo L. A global double-fluorescent Cre reporter mouse. Genesis 2007, 45:593-605. 10.1002/dvg.20335, 17868096.
-
(2007)
Genesis
, vol.45
, pp. 593-605
-
-
Muzumdar, M.D.1
Tasic, B.2
Miyamichi, K.3
Li, L.4
Luo, L.5
-
26
-
-
0036677403
-
Early restriction of peripheral and proximal cell lineages during formation of the lung
-
10.1073/pnas.152238499, 124949, 12145322
-
Perl AK, Wert SE, Nagy A, Lobe CG, Whitsett JA. Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc Natl Acad Sci USA 2002, 99:10482-10487. 10.1073/pnas.152238499, 124949, 12145322.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10482-10487
-
-
Perl, A.K.1
Wert, S.E.2
Nagy, A.3
Lobe, C.G.4
Whitsett, J.A.5
-
27
-
-
58849135842
-
The effect of thrombospondin-1 on breast cancer metastasis
-
10.1007/s10549-008-9992-6, 2631620, 18409060
-
Yee KO, Connolly CM, Duquette M, Kazerounian S, Washington R, Lawler J. The effect of thrombospondin-1 on breast cancer metastasis. Breast Cancer Res Treat 2009, 114:85-96. 10.1007/s10549-008-9992-6, 2631620, 18409060.
-
(2009)
Breast Cancer Res Treat
, vol.114
, pp. 85-96
-
-
Yee, K.O.1
Connolly, C.M.2
Duquette, M.3
Kazerounian, S.4
Washington, R.5
Lawler, J.6
-
28
-
-
0037698263
-
Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression
-
10.1074/jbc.M302238200, 12740377
-
Connelly L, Jacobs AT, Palacios-Callender M, Moncada S, Hobbs AJ. Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression. J Biol Chem 2003, 278:26480-26487. 10.1074/jbc.M302238200, 12740377.
-
(2003)
J Biol Chem
, vol.278
, pp. 26480-26487
-
-
Connelly, L.1
Jacobs, A.T.2
Palacios-Callender, M.3
Moncada, S.4
Hobbs, A.J.5
-
29
-
-
33845534522
-
Effect of tumor-derived cytokines and growth factors on differentiation and immune suppressive features of myeloid cells in cancer
-
10.1007/s10555-006-9002-6, 1693571, 16983515
-
Kusmartsev S, Gabrilovich DI. Effect of tumor-derived cytokines and growth factors on differentiation and immune suppressive features of myeloid cells in cancer. Cancer Metastasis Rev 2006, 25:323-331. 10.1007/s10555-006-9002-6, 1693571, 16983515.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 323-331
-
-
Kusmartsev, S.1
Gabrilovich, D.I.2
-
30
-
-
65249138393
-
Myeloid-derived suppressor cells: linking inflammation and cancer
-
10.4049/jimmunol.0802740, 2810498, 19342621
-
Ostrand-Rosenberg S, Sinha P. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 2009, 182:4499-4506. 10.4049/jimmunol.0802740, 2810498, 19342621.
-
(2009)
J Immunol
, vol.182
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
31
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
10.1038/nri2448, 2724991, 19029990
-
Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008, 8:958-969. 10.1038/nri2448, 2724991, 19029990.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
32
-
-
0041832322
-
Dynamics of macrophage cell populations during murine pulmonary tuberculosis
-
Gonzalez-Juarrero M, Shim TS, Kipnis A, Junqueira-Kipnis AP, Orme IM. Dynamics of macrophage cell populations during murine pulmonary tuberculosis. J Immunol 2003, 171:3128-3135.
-
(2003)
J Immunol
, vol.171
, pp. 3128-3135
-
-
Gonzalez-Juarrero, M.1
Shim, T.S.2
Kipnis, A.3
Junqueira-Kipnis, A.P.4
Orme, I.M.5
-
33
-
-
56149103896
-
Macrophage polarization in bacterial infections
-
Benoit M, Desnues B, Mege JL. Macrophage polarization in bacterial infections. J Immunol 2008, 181:3733-3739.
-
(2008)
J Immunol
, vol.181
, pp. 3733-3739
-
-
Benoit, M.1
Desnues, B.2
Mege, J.L.3
-
34
-
-
34247489551
-
Immune-mediated modulation of breast cancer growth and metastasis by the chemokine Mig (CXCL9) in a murine model
-
10.1097/CJI.0b013e318031b551, 17589289
-
Walser TC, Ma X, Kundu N, Dorsey R, Goloubeva O, Fulton AM. Immune-mediated modulation of breast cancer growth and metastasis by the chemokine Mig (CXCL9) in a murine model. J Immunother 2007, 30:490-498. 10.1097/CJI.0b013e318031b551, 17589289.
-
(2007)
J Immunother
, vol.30
, pp. 490-498
-
-
Walser, T.C.1
Ma, X.2
Kundu, N.3
Dorsey, R.4
Goloubeva, O.5
Fulton, A.M.6
-
35
-
-
33845752914
-
P50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
-
10.1158/0008-5472.CAN-06-1867, 17145890
-
Saccani A, Schioppa T, Porta C, Biswas SK, Nebuloni M, Vago L, Bottazzi B, Colombo MP, Mantovani A, Sica A. p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res 2006, 66:11432-11440. 10.1158/0008-5472.CAN-06-1867, 17145890.
-
(2006)
Cancer Res
, vol.66
, pp. 11432-11440
-
-
Saccani, A.1
Schioppa, T.2
Porta, C.3
Biswas, S.K.4
Nebuloni, M.5
Vago, L.6
Bottazzi, B.7
Colombo, M.P.8
Mantovani, A.9
Sica, A.10
-
36
-
-
63149160727
-
Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB
-
10.1182/blood-2008-12-172825, 2869029, 19171876
-
Hagemann T, Biswas SK, Lawrence T, Sica A, Lewis CE. Regulation of macrophage function in tumors: the multifaceted role of NF-kappaB. Blood 2009, 113:3139-3146. 10.1182/blood-2008-12-172825, 2869029, 19171876.
-
(2009)
Blood
, vol.113
, pp. 3139-3146
-
-
Hagemann, T.1
Biswas, S.K.2
Lawrence, T.3
Sica, A.4
Lewis, C.E.5
-
37
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
10.1016/j.cell.2010.03.014, 20371344
-
Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell 2010, 141:39-51. 10.1016/j.cell.2010.03.014, 20371344.
-
(2010)
Cell
, vol.141
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
38
-
-
1842784436
-
Identification of the molecular mechanism by which TLR ligation and IFN-gamma synergize to induce MIG
-
10.1080/10446670410001670535, 2275409, 15154616
-
Powell JD, Boodoo S, Horton MR. Identification of the molecular mechanism by which TLR ligation and IFN-gamma synergize to induce MIG. Clin Dev Immunol 2004, 11:77-85. 10.1080/10446670410001670535, 2275409, 15154616.
-
(2004)
Clin Dev Immunol
, vol.11
, pp. 77-85
-
-
Powell, J.D.1
Boodoo, S.2
Horton, M.R.3
-
39
-
-
72549111131
-
The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy
-
10.1517/14728220903431069, 3043547, 20001209
-
Lin Y, Bai L, Chen W, Xu S. The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy. Expert Opin Ther Targets 2010, 14:45-55. 10.1517/14728220903431069, 3043547, 20001209.
-
(2010)
Expert Opin Ther Targets
, vol.14
, pp. 45-55
-
-
Lin, Y.1
Bai, L.2
Chen, W.3
Xu, S.4
|