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Volumn 6, Issue 7, 2015, Pages 1137-1142

Htr2a Expression Responds Rapidly to Environmental Stimuli in an Egr3 -Dependent Manner

Author keywords

5 HT2AR; early growth response 3; Egr3; Htr2a; immediate early gene; Schizophrenia; serotonin 2A receptor; sleep deprivation

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 3; MESSENGER RNA; SEROTONIN 2A RECEPTOR; EGR3 PROTEIN, MOUSE; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN;

EID: 84937032640     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/acschemneuro.5b00031     Document Type: Article
Times cited : (21)

References (44)
  • 1
    • 0026084805 scopus 로고
    • The genetic epidemiology of schizophrenia and the design of linkage studies
    • McGue, M. and Gottesman, I. I. (1991) The genetic epidemiology of schizophrenia and the design of linkage studies Eur. Arch. Psychiatry Clin. Neurosci. 240, 174-181
    • (1991) Eur. Arch. Psychiatry Clin. Neurosci. , vol.240 , pp. 174-181
    • McGue, M.1    Gottesman, I.I.2
  • 4
    • 17844377615 scopus 로고    scopus 로고
    • HTR2A: Association and expression studies in neuropsychiatric genetics
    • Norton, N. and Owen, M. J. (2005) HTR2A: association and expression studies in neuropsychiatric genetics Ann. Med. 37, 121-129
    • (2005) Ann. Med. , vol.37 , pp. 121-129
    • Norton, N.1    Owen, M.J.2
  • 6
    • 0030592323 scopus 로고    scopus 로고
    • Decreased frontal cortical serotonin2A receptors in schizophrenia
    • Dean, B. and Hayes, W. (1996) Decreased frontal cortical serotonin2A receptors in schizophrenia Schizophr. Res. 21, 133-139
    • (1996) Schizophr. Res. , vol.21 , pp. 133-139
    • Dean, B.1    Hayes, W.2
  • 10
    • 78249256348 scopus 로고    scopus 로고
    • The environment and susceptibility to schizophrenia
    • Brown, A. S. (2011) The environment and susceptibility to schizophrenia Prog. Neurobiol. 93, 23-58
    • (2011) Prog. Neurobiol. , vol.93 , pp. 23-58
    • Brown, A.S.1
  • 11
    • 0003128501 scopus 로고    scopus 로고
    • The neurobiology of the stress cascade and its potential relevance for schizophrenia
    • Corcoran, C., Gallitano, A., Leitman, D., and Malaspina, D. (2001) The neurobiology of the stress cascade and its potential relevance for schizophrenia J. Psychiatr. Pract. 7, 3-14
    • (2001) J. Psychiatr. Pract. , vol.7 , pp. 3-14
    • Corcoran, C.1    Gallitano, A.2    Leitman, D.3    Malaspina, D.4
  • 13
    • 54249162304 scopus 로고    scopus 로고
    • Gene-environment interaction and covariation in schizophrenia: The role of obstetric complications
    • Mittal, V. A., Ellman, L. M., and Cannon, T. D. (2008) Gene-environment interaction and covariation in schizophrenia: the role of obstetric complications Schizophr. Bull. 34, 1083-1094
    • (2008) Schizophr. Bull. , vol.34 , pp. 1083-1094
    • Mittal, V.A.1    Ellman, L.M.2    Cannon, T.D.3
  • 14
    • 54249120358 scopus 로고    scopus 로고
    • Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction
    • van Winkel, R., Stefanis, N. C., and Myin-Germeys, I. (2008) Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction Schizophr. Bull. 34, 1095-1105
    • (2008) Schizophr. Bull. , vol.34 , pp. 1095-1105
    • Van Winkel, R.1    Stefanis, N.C.2    Myin-Germeys, I.3
  • 15
    • 84870573114 scopus 로고    scopus 로고
    • Sleep deprivation increases cerebral serotonin 2A receptor binding in humans
    • Elmenhorst, D., Kroll, T., Matusch, A., and Bauer, A. (2012) Sleep deprivation increases cerebral serotonin 2A receptor binding in humans Sleep 35, 1615-1623
    • (2012) Sleep , vol.35 , pp. 1615-1623
    • Elmenhorst, D.1    Kroll, T.2    Matusch, A.3    Bauer, A.4
  • 16
    • 42049118043 scopus 로고    scopus 로고
    • Mice lacking the immediate early gene Egr3 respond to the anti-aggressive effects of clozapine yet are relatively resistant to its sedating effects
    • Gallitano-Mendel, A., Wozniak, D. F., Pehek, E. A., and Milbrandt, J. (2008) Mice lacking the immediate early gene Egr3 respond to the anti-aggressive effects of clozapine yet are relatively resistant to its sedating effects Neuropsychopharmacology 33, 1266-1275
    • (2008) Neuropsychopharmacology , vol.33 , pp. 1266-1275
    • Gallitano-Mendel, A.1    Wozniak, D.F.2    Pehek, E.A.3    Milbrandt, J.4
  • 19
    • 33847337446 scopus 로고    scopus 로고
    • Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia
    • Yamada, K., Gerber, D. J., Iwayama, Y., Ohnishi, T., Ohba, H., Toyota, T., Aruga, J., Minabe, Y., Tonegawa, S., and Yoshikawa, T. (2007) Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia Proc. Natl. Acad. Sci. U. S. A. 104, 2815-2820
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 2815-2820
    • Yamada, K.1    Gerber, D.J.2    Iwayama, Y.3    Ohnishi, T.4    Ohba, H.5    Toyota, T.6    Aruga, J.7    Minabe, Y.8    Tonegawa, S.9    Yoshikawa, T.10
  • 20
    • 84856061141 scopus 로고    scopus 로고
    • Genetic evidence for the association between the early growth response 3 (EGR3) gene and schizophrenia
    • Zhang, R., Lu, S., Meng, L., Min, Z., Tian, J., Valenzuela, R. K., Guo, T., Tian, L., Zhao, W., and Ma, J. (2012) Genetic evidence for the association between the early growth response 3 (EGR3) gene and schizophrenia PloS One 7, e30237
    • (2012) PloS One , vol.7 , pp. 30237
    • Zhang, R.1    Lu, S.2    Meng, L.3    Min, Z.4    Tian, J.5    Valenzuela, R.K.6    Guo, T.7    Tian, L.8    Zhao, W.9    Ma, J.10
  • 22
    • 77956571618 scopus 로고    scopus 로고
    • Htr2a Gene and 5-HT(2A) Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice
    • Weber, E. T. and Andrade, R. (2010) Htr2a Gene and 5-HT(2A) Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice Front. Neurosci. 10.3389/fnins.2010.00036
    • (2010) Front. Neurosci.
    • Weber, E.T.1    Andrade, R.2
  • 24
    • 0141753077 scopus 로고    scopus 로고
    • Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex
    • Gonzalez-Maeso, J., Yuen, T., Ebersole, B. J., Wurmbach, E., Lira, A., Zhou, M., Weisstaub, N., Hen, R., Gingrich, J. A., and Sealfon, S. C. (2003) Transcriptome fingerprints distinguish hallucinogenic and nonhallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in mouse somatosensory cortex J. Neurosci. 23, 8836-8843
    • (2003) J. Neurosci. , vol.23 , pp. 8836-8843
    • Gonzalez-Maeso, J.1    Yuen, T.2    Ebersole, B.J.3    Wurmbach, E.4    Lira, A.5    Zhou, M.6    Weisstaub, N.7    Hen, R.8    Gingrich, J.A.9    Sealfon, S.C.10
  • 25
    • 84874801830 scopus 로고    scopus 로고
    • HTR2A-1438A/G polymorphism influences the risk of schizophrenia but not bipolar disorder or major depressive disorder: A meta-analysis
    • Gu, L., Long, J., Yan, Y., Chen, Q., Pan, R., Xie, X., Mao, X., Hu, X., Wei, B., and Su, L. (2013) HTR2A-1438A/G polymorphism influences the risk of schizophrenia but not bipolar disorder or major depressive disorder: a meta-analysis J. Neurosci. Res. 91, 623-633
    • (2013) J. Neurosci. Res. , vol.91 , pp. 623-633
    • Gu, L.1    Long, J.2    Yan, Y.3    Chen, Q.4    Pan, R.5    Xie, X.6    Mao, X.7    Hu, X.8    Wei, B.9    Su, L.10
  • 27
    • 33947645942 scopus 로고    scopus 로고
    • The effects of sleep deprivation on symptoms of psychopathology in healthy adults
    • Kahn-Greene, E. T., Killgore, D. B., Kamimori, G. H., Balkin, T. J., and Killgore, W. D. (2007) The effects of sleep deprivation on symptoms of psychopathology in healthy adults Sleep Med. 8, 215-221
    • (2007) Sleep Med. , vol.8 , pp. 215-221
    • Kahn-Greene, E.T.1    Killgore, D.B.2    Kamimori, G.H.3    Balkin, T.J.4    Killgore, W.D.5
  • 28
    • 13444311818 scopus 로고    scopus 로고
    • Differential regulation of serotonin (5HT)2A receptor mRNA and protein levels after single and repeated stress in rat brain: Role in learned helplessness behavior
    • Dwivedi, Y., Mondal, A. C., Payappagoudar, G. V., and Rizavi, H. S. (2005) Differential regulation of serotonin (5HT)2A receptor mRNA and protein levels after single and repeated stress in rat brain: role in learned helplessness behavior Neuropharmacology 48, 204-214
    • (2005) Neuropharmacology , vol.48 , pp. 204-214
    • Dwivedi, Y.1    Mondal, A.C.2    Payappagoudar, G.V.3    Rizavi, H.S.4
  • 29
    • 27944436465 scopus 로고    scopus 로고
    • The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors
    • Li, L., Carter, J., Gao, X., Whitehead, J., and Tourtellotte, W. G. (2005) The neuroplasticity-associated arc gene is a direct transcriptional target of early growth response (Egr) transcription factors Mol. Cell. Biol. 25, 10286-10300
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 10286-10300
    • Li, L.1    Carter, J.2    Gao, X.3    Whitehead, J.4    Tourtellotte, W.G.5
  • 31
    • 77949426688 scopus 로고    scopus 로고
    • A novel microRNA and transcription factor mediated regulatory network in schizophrenia
    • Guo, A. Y., Sun, J., Jia, P., and Zhao, Z. (2010) A novel microRNA and transcription factor mediated regulatory network in schizophrenia BMC Syst. Biol. 4, 10
    • (2010) BMC Syst. Biol. , vol.4 , pp. 10
    • Guo, A.Y.1    Sun, J.2    Jia, P.3    Zhao, Z.4
  • 32
    • 24944483155 scopus 로고    scopus 로고
    • Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers
    • Mexal, S., Frank, M., Berger, R., Adams, C. E., Ross, R. G., Freedman, R., and Leonard, S. (2005) Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers Brain Res. Mol. Brain Res. 139, 317-332
    • (2005) Brain Res. Mol. Brain Res. , vol.139 , pp. 317-332
    • Mexal, S.1    Frank, M.2    Berger, R.3    Adams, C.E.4    Ross, R.G.5    Freedman, R.6    Leonard, S.7
  • 34
    • 50349096587 scopus 로고    scopus 로고
    • In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems
    • Meltzer, H. Y. and Huang, M. (2008) In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems Prog. Brain Res. 172, 177-197
    • (2008) Prog. Brain Res. , vol.172 , pp. 177-197
    • Meltzer, H.Y.1    Huang, M.2
  • 35
    • 0025921604 scopus 로고
    • Serotonin2 (5-HT2) receptor binding in the frontal cortex of schizophrenic patients
    • Arora, R. C. and Meltzer, H. Y. (1991) Serotonin2 (5-HT2) receptor binding in the frontal cortex of schizophrenic patients J. Neural Transm.: Gen. Sect. 85, 19-29
    • (1991) J. Neural Transm.: Gen. Sect. , vol.85 , pp. 19-29
    • Arora, R.C.1    Meltzer, H.Y.2
  • 37
    • 0034051207 scopus 로고    scopus 로고
    • Decreased serotonin 2A receptor densities in neuroleptic-naive patients with schizophrenia: A PET study using [(18)F]setoperone
    • Ngan, E. T., Yatham, L. N., Ruth, T. J., and Liddle, P. F. (2000) Decreased serotonin 2A receptor densities in neuroleptic-naive patients with schizophrenia: A PET study using [(18)F]setoperone Am. J. Psychiatry 157, 1016-1018
    • (2000) Am. J. Psychiatry , vol.157 , pp. 1016-1018
    • Ngan, E.T.1    Yatham, L.N.2    Ruth, T.J.3    Liddle, P.F.4
  • 38
    • 0029891621 scopus 로고    scopus 로고
    • The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain
    • Burnet, P. W., Chen, C. P., McGowan, S., Franklin, M., and Harrison, P. J. (1996) The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain Neuroscience 73, 531-540
    • (1996) Neuroscience , vol.73 , pp. 531-540
    • Burnet, P.W.1    Chen, C.P.2    McGowan, S.3    Franklin, M.4    Harrison, P.J.5
  • 39
    • 0030273870 scopus 로고    scopus 로고
    • 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia
    • Burnet, P. W., Eastwood, S. L., and Harrison, P. J. (1996) 5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia Neuropsychopharmacology 15, 442-455
    • (1996) Neuropsychopharmacology , vol.15 , pp. 442-455
    • Burnet, P.W.1    Eastwood, S.L.2    Harrison, P.J.3
  • 40
    • 0034650980 scopus 로고    scopus 로고
    • Abnormalities in 5-HT2A receptor mRNA expression in frontal cortex of chronic elderly schizophrenics with varying histories of neuroleptic treatment
    • Hernandez, I. and Sokolov, B. P. (2000) Abnormalities in 5-HT2A receptor mRNA expression in frontal cortex of chronic elderly schizophrenics with varying histories of neuroleptic treatment J. Neurosci. Res. 59, 218-225
    • (2000) J. Neurosci. Res. , vol.59 , pp. 218-225
    • Hernandez, I.1    Sokolov, B.P.2
  • 41
    • 0031710559 scopus 로고    scopus 로고
    • Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3
    • Tourtellotte, W. G. and Milbrandt, J. (1998) Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3 Nat. Genet. 20, 87-91
    • (1998) Nat. Genet. , vol.20 , pp. 87-91
    • Tourtellotte, W.G.1    Milbrandt, J.2
  • 42
    • 49049110545 scopus 로고    scopus 로고
    • Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains
    • Wisor, J. P., Pasumarthi, R. K., Gerashchenko, D., Thompson, C. L., Pathak, S., Sancar, A., Franken, P., Lein, E. S., and Kilduff, T. S. (2008) Sleep deprivation effects on circadian clock gene expression in the cerebral cortex parallel electroencephalographic differences among mouse strains J. Neurosci. 28, 7193-7201
    • (2008) J. Neurosci. , vol.28 , pp. 7193-7201
    • Wisor, J.P.1    Pasumarthi, R.K.2    Gerashchenko, D.3    Thompson, C.L.4    Pathak, S.5    Sancar, A.6    Franken, P.7    Lein, E.S.8    Kilduff, T.S.9
  • 43
    • 0021745136 scopus 로고
    • Effect of sleep deprivation on sleep and EEG power spectra in the rat
    • Borbely, A. A., Tobler, I., and Hanagasioglu, M. (1984) Effect of sleep deprivation on sleep and EEG power spectra in the rat Behav. Brain Res. 14, 171-182
    • (1984) Behav. Brain Res. , vol.14 , pp. 171-182
    • Borbely, A.A.1    Tobler, I.2    Hanagasioglu, M.3


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