Mice lacking the immediate early gene Egr3 respond to the anti-aggressive effects of clozapine yet are relatively resistant to its sedating effects

Neuropsychopharmacology

Volumn 33, Issue 6, 2008, Pages 1266-1275

  Gallitano Mendel, Amelia ^a,b   Wozniak, David F ^a   Pehek, Elizabeth A ^c   Milbrandt, Jeffrey ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Behavior; Clozapine; Egr3; Immediate early gene; Schizophrenia; Stress

Indexed keywords

CLOZAPINE; EARLY GROWTH RESPONSE FACTOR 3;

AGGRESSION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMEDIATE EARLY GENE; IMPULSIVENESS; LATENT PERIOD; MALE; MOUSE; NEUROBIOLOGY; NONHUMAN; PRIORITY JOURNAL; SEDATION; SOCIAL STRESS; TREATMENT RESPONSE;

AGGRESSION; ANALYSIS OF VARIANCE; ANIMALS; ANTIPSYCHOTIC AGENTS; BEHAVIOR, ANIMAL; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLOZAPINE; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EARLY GROWTH RESPONSE PROTEIN 3; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; REACTION TIME; SEROTONIN;

EID: 42049118043     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301505     Document Type: Article

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