Design of Cationic Multiwalled Carbon Nanotubes as Efficient siRNA Vectors for Lung Cancer Xenograft Eradication

Bioconjugate Chemistry

Volumn 26, Issue 7, 2015, Pages 1370-1379

  Guo, Chang ^a   Al Jamal, Wafa T ^a   Toma, Francesca M ^b   Bianco, Alberto ^c   Prato, Maurizio ^b   Al Jamal, Khuloud T ^a,d   Kostarelos, Kostas ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF TRIESTE   (Italy)

^c INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; DISEASES; GENE THERAPY; LIPOSOMES; MEDICAL APPLICATIONS; MULTIWALLED CARBON NANOTUBES (MWCN); YARN;

BIOMEDICAL APPLICATIONS; CANCER GENE THERAPY; CANCER THERAPY; CATIONICS; CHEMICALLY FUNCTIONALIZED CARBON NANOTUBE; LUNG CANCER; MULTI-WALLED-CARBON-NANOTUBES; POLO-LIKE KINASE; POTENTIAL TARGETS; THERAPEUTIC EFFICACY;

TUMORS;

AMMONIA; FLUORESCENT DYE; MULTI WALLED NANOTUBE; POLO LIKE KINASE 1; SMALL INTERFERING RNA; CARBON NANOTUBE; CATION; CELL CYCLE PROTEIN; ONCOPROTEIN; POLO-LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE;

ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GENE THERAPY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG EFFICACY; ERADICATION THERAPY; FEMALE; GENE SILENCING; GENE TARGETING; GENE VECTOR; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG CARCINOMA; MOUSE; NANOTECHNOLOGY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL RATE; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT; TUNEL ASSAY; WESTERN BLOTTING; ADMINISTRATION AND DOSAGE; ANIMAL; CHEMISTRY; GENETICS; LUNG; LUNG NEOPLASMS; METABOLISM; NUDE MOUSE; PATHOLOGY; RNA INTERFERENCE; RNAI THERAPEUTICS; TUMOR CELL LINE;

ANIMALIA;

ANIMALS; APOPTOSIS; CATIONS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; FEMALE; GENETIC VECTORS; HUMANS; LUNG; LUNG NEOPLASMS; MICE, NUDE; NANOTUBES, CARBON; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; RNAI THERAPEUTICS;

EID: 84937030517     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.5b00249     Document Type: Article

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