Transplantation of NSC-derived cholinergic neuron-like cells improves cognitive function in APP/PS1 transgenic mice

Neuroscience

Volumn 291, Issue , 2015, Pages 81-92

  Gu, G ^a   Zhang, W ^a   Li, M ^a   Ni, J ^a   Wang, P ^a  

^a TONGJI UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Cholinergic neuron like cells; Nerve growth factor; Neural stem cells; Retinoic acid; Transplantation

Indexed keywords

ACETYLCHOLINE; CHOLINE ACETYLTRANSFERASE; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; NERVE GROWTH FACTOR; RETINOIC ACID; 5' NUCLEOTIDASE; AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; GLYCOPROTEIN; NT5C3 PROTEIN, HUMAN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CELL CULTURE; CELL DIFFERENTIATION; CHOLINERGIC NERVE CELL; COGNITION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; HIPPOCAMPUS; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; LEARNING; MALE; MEMORY; MORRIS WATER MAZE TEST; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ALZHEIMER DISEASE; ANIMAL; C57BL MOUSE; COGNITION DISORDERS; GENETICS; MAZE TEST; METABOLISM; NERVOUS SYSTEM DEVELOPMENT; PATHOPHYSIOLOGY; PHYSIOLOGY; PLAQUE, AMYLOID; PROCEDURES; RANDOMIZATION; SPATIAL MEMORY; STEM CELL TRANSPLANTATION; TRANSGENIC MOUSE; TRANSPLANTATION;

5'-NUCLEOTIDASE; ACETYLCHOLINE; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC NEURONS; COGNITION DISORDERS; GLYCOPROTEINS; GREEN FLUORESCENT PROTEINS; HIPPOCAMPUS; MALE; MAZE LEARNING; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL STEM CELLS; NEUROGENESIS; PLAQUE, AMYLOID; RANDOM ALLOCATION; RNA, MESSENGER; SPATIAL MEMORY; STEM CELL TRANSPLANTATION;

EID: 84936998488     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.01.073     Document Type: Article

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