-
1
-
-
77952566949
-
Mechanisms, regulation and consequences of protein SUMOylation
-
K. A. Wilkinson, J. M. Henley, Mechanisms, regulation and consequences of protein SUMOylation. Biochem. J. 428, 133-145 (2010).
-
(2010)
Biochem. J.
, vol.428
, pp. 133-145
-
-
Wilkinson, K.A.1
Henley, J.M.2
-
2
-
-
34548483908
-
SUMO-specific proteases: A twist in the tail
-
R. T. Hay, SUMO-specific proteases: A twist in the tail. Trends Cell Biol. 17, 370-376 (2007).
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 370-376
-
-
Hay, R.T.1
-
3
-
-
84897139297
-
Identification and analysis of endogenous SUMO1 and SUMO2/3 targets in mammalian cells and tissues using monoclonal antibodies
-
S. V. Barysch, C. Dittner, A. Flotho, J. Becker, F. Melchior, Identification and analysis of endogenous SUMO1 and SUMO2/3 targets in mammalian cells and tissues using monoclonal antibodies. Nat. Protoc. 9, 896-909 (2014).
-
(2014)
Nat. Protoc.
, vol.9
, pp. 896-909
-
-
Barysch, S.V.1
Dittner, C.2
Flotho, A.3
Becker, J.4
Melchior, F.5
-
4
-
-
0035929557
-
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
-
M. H. Tatham, E. Jaffray, O. A. Vaughan, J. M. Desterro, C. H. Botting, J. H. Naismith, R. T. Hay, Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9. J. Biol. Chem. 276, 35368-35374 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35368-35374
-
-
Tatham, M.H.1
Jaffray, E.2
Vaughan, O.A.3
Desterro, J.M.4
Botting, C.H.5
Naismith, J.H.6
Hay, R.T.7
-
5
-
-
39049093685
-
In vivo identification of human small ubiquitinlike modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy
-
I. Matic, M. van Hagen, J. Schimmel, B. Macek, S. C. Ogg, M. H. Tatham, R. T. Hay, A. I. Lamond, M. Mann, A. C. Vertegaal, In vivo identification of human small ubiquitinlike modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy. Mol. Cell. Proteomics 7, 132-144 (2008).
-
(2008)
Mol. Cell. Proteomics
, vol.7
, pp. 132-144
-
-
Matic, I.1
Van Hagen, M.2
Schimmel, J.3
Macek, B.4
Ogg, S.C.5
Tatham, M.H.6
Hay, R.T.7
Lamond, A.I.8
Mann, M.9
Vertegaal, A.C.10
-
6
-
-
43049093756
-
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
-
M. H. Tatham, M. C. Geoffroy, L. Shen, A. Plechanovova, N. Hattersley, E. G. Jaffray, J. J. Palvimo, R. T. Hay, RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. Nat. Cell Biol. 10, 538-546 (2008).
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 538-546
-
-
Tatham, M.H.1
Geoffroy, M.C.2
Shen, L.3
Plechanovova, A.4
Hattersley, N.5
Jaffray, E.G.6
Palvimo, J.J.7
Hay, R.T.8
-
7
-
-
34547683267
-
SUMO junction - What's your function? New insights through SUMO-interacting motifs
-
O. Kerscher, SUMO junction - What's your function? New insights through SUMO-interacting motifs. EMBO Rep. 8, 550-555 (2007).
-
(2007)
EMBO Rep.
, vol.8
, pp. 550-555
-
-
Kerscher, O.1
-
8
-
-
0030794729
-
The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer
-
E. S. Johnson, I. Schwienhorst, R. J. Dohmen, G. Blobel, The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J. 16, 5509-5519 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 5509-5519
-
-
Johnson, E.S.1
Schwienhorst, I.2
Dohmen, R.J.3
Blobel, G.4
-
9
-
-
0034676457
-
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
-
A. G. Fraser, R. S. Kamath, P. Zipperlen, M. Martinez-Campos, M. Sohrmann, J. Ahringer, Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 408, 325-330 (2000).
-
(2000)
Nature
, vol.408
, pp. 325-330
-
-
Fraser, A.G.1
Kamath, R.S.2
Zipperlen, P.3
Martinez-Campos, M.4
Sohrmann, M.5
Ahringer, J.6
-
10
-
-
0033508431
-
Characterization of a fission yeast SUMO-1 homologue, pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation
-
K. Tanaka, J. Nishide, K. Okazaki, H. Kato, O. Niwa, T. Nakagawa, H. Matsuda, M. Kawamukai, Y. Murakami, Characterization of a fission yeast SUMO-1 homologue, pmt3p, required for multiple nuclear events, including the control of telomere length and chromosome segregation. Mol. Cell. Biol. 19, 8660-8672 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 8660-8672
-
-
Tanaka, K.1
Nishide, J.2
Okazaki, K.3
Kato, H.4
Niwa, O.5
Nakagawa, T.6
Matsuda, H.7
Kawamukai, M.8
Murakami, Y.9
-
11
-
-
34548691835
-
Genetic analysis of SUMOylation in Arabidopsis: Conjugation of SUMO1 and SUMO2 to nuclear proteins is essential
-
S. A. Saracco, M. J. Miller, J. Kurepa, R. D. Vierstra, Genetic analysis of SUMOylation in Arabidopsis: Conjugation of SUMO1 and SUMO2 to nuclear proteins is essential. Plant Physiol. 145, 119-134 (2007).
-
(2007)
Plant Physiol.
, vol.145
, pp. 119-134
-
-
Saracco, S.A.1
Miller, M.J.2
Kurepa, J.3
Vierstra, R.D.4
-
12
-
-
28444448039
-
The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice
-
K. Nacerddine, F. Lehembre, M. Bhaumik, J. Artus, M. Cohen-Tannoudji, C. Babinet, P. P. Pandolfi, A. Dejean, The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice. Dev. Cell 9, 769-779 (2005).
-
(2005)
Dev. Cell
, vol.9
, pp. 769-779
-
-
Nacerddine, K.1
Lehembre, F.2
Bhaumik, M.3
Artus, J.4
Cohen-Tannoudji, M.5
Babinet, C.6
Pandolfi, P.P.7
Dejean, A.8
-
13
-
-
59349108844
-
Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3
-
E. Evdokimov, P. Sharma, S. J. Lockett, M. Lualdi, M. R. Kuehn, Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3. J. Cell Sci. 121, 4106-4113 (2008).
-
(2008)
J. Cell Sci.
, vol.121
, pp. 4106-4113
-
-
Evdokimov, E.1
Sharma, P.2
Lockett, S.J.3
Lualdi, M.4
Kuehn, M.R.5
-
14
-
-
50249096810
-
Sumo-1 function is dispensable in normal mouse development
-
F. P. Zhang, L. Mikkonen, J. Toppari, J. J. Palvimo, I. Thesleff, O. A. Ja¨nne, Sumo-1 function is dispensable in normal mouse development. Mol. Cell. Biol. 28, 5381-5390 (2008).
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 5381-5390
-
-
Zhang, F.P.1
Mikkonen, L.2
Toppari, J.3
Palvimo, J.J.4
Thesleff, I.5
Ja¨nne, O.A.6
-
15
-
-
0034054669
-
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3
-
H. Saitoh, J. Hinchey, Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3. J. Biol. Chem. 275, 6252-6258 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 6252-6258
-
-
Saitoh, H.1
Hinchey, J.2
-
16
-
-
79959381925
-
Comparative proteomic analysis identifies a role for SUMO in protein quality control
-
M. H. Tatham, I. Matic, M. Mann, R. T. Hay, Comparative proteomic analysis identifies a role for SUMO in protein quality control. Sci. Signal. 4, rs4 (2011).
-
(2011)
Sci. Signal.
, vol.4
, pp. rs4
-
-
Tatham, M.H.1
Matic, I.2
Mann, M.3
Hay, R.T.4
-
17
-
-
67649173012
-
System-wide changes to SUMO modifications in response to heat shock
-
F.Golebiowski, I. Matic, M. H. Tatham, C. Cole, Y. Yin, A. Nakamura, J. Cox, G. J. Barton, M. Mann, R. T. Hay, System-wide changes to SUMO modifications in response to heat shock. Sci. Signal. 2, ra24 (2009).
-
(2009)
Sci. Signal.
, vol.2
, pp. ra24
-
-
Golebiowski, F.1
Matic, I.2
Tatham, M.H.3
Cole, C.4
Yin, Y.5
Nakamura, A.6
Cox, J.7
Barton, G.J.8
Mann, M.9
Hay, R.T.10
-
18
-
-
84874050141
-
Quantitative proteomics reveals factors regulating RNA biology as dynamic targets of stress-induced SUMOylation in Arabidopsis
-
M. J. Miller, M. Scalf, T. C. Rytz, S. L. Hubler, L. M. Smith, R. D. Vierstra, Quantitative proteomics reveals factors regulating RNA biology as dynamic targets of stress-induced SUMOylation in Arabidopsis. Mol. Cell. Proteomics 12, 449-463 (2013).
-
(2013)
Mol. Cell. Proteomics
, vol.12
, pp. 449-463
-
-
Miller, M.J.1
Scalf, M.2
Rytz, T.C.3
Hubler, S.L.4
Smith, L.M.5
Vierstra, R.D.6
-
19
-
-
33845630288
-
SIZ1 small ubiquitin-like modifier E3 ligase facilitates basal thermotolerance in Arabidopsis independent of salicylic acid
-
C. Y. Yoo, K. Miura, J. B. Jin, J. Lee, H. C. Park, D. E. Salt, D. J. Yun, R. A. Bressan, P. M. Hasegawa, SIZ1 small ubiquitin-like modifier E3 ligase facilitates basal thermotolerance in Arabidopsis independent of salicylic acid. Plant Physiol. 142, 1548-1558 (2006).
-
(2006)
Plant Physiol.
, vol.142
, pp. 1548-1558
-
-
Yoo, C.Y.1
Miura, K.2
Jin, J.B.3
Lee, J.4
Park, H.C.5
Salt, D.E.6
Yun, D.J.7
Bressan, R.A.8
Hasegawa, P.M.9
-
20
-
-
0037470238
-
The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress
-
J. Kurepa, J. M. Walker, J. Smalle, M. M. Gosink, S. J. Davis, T. L. Durham, D. Y. Sung, R. D. Vierstra, The small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis. Accumulation of SUMO1 and -2 conjugates is increased by stress. J. Biol. Chem. 278, 6862-6872 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6862-6872
-
-
Kurepa, J.1
Walker, J.M.2
Smalle, J.3
Gosink, M.M.4
Davis, S.J.5
Durham, T.L.6
Sung, D.Y.7
Vierstra, R.D.8
-
21
-
-
79551604903
-
Purification and identification of endogenous polySUMO conjugates
-
R. Bruderer, M. H. Tatham, A. Plechanovova, I. Matic, A. K. Garg, R. T. Hay, Purification and identification of endogenous polySUMO conjugates. EMBO Rep. 12, 142-148 (2011).
-
(2011)
EMBO Rep.
, vol.12
, pp. 142-148
-
-
Bruderer, R.1
Tatham, M.H.2
Plechanovova, A.3
Matic, I.4
Garg, A.K.5
Hay, R.T.6
-
22
-
-
84940001123
-
cerevisiae SUMO stress response is a conjugation-deconjugation cycle that targets the transcription machinery
-
M. C. Lewicki, T. Srikumar, E. Johnson, B. Raught, The S. cerevisiae SUMO stress response is a conjugation-deconjugation cycle that targets the transcription machinery. J. Proteomics 118, 39-48 (2015).
-
(2015)
J. Proteomics
, vol.118
, pp. 39-48
-
-
Lewicki, M.C.1
Srikumar, T.2
Johnson, E.3
Raught, B.4
The, S.5
-
23
-
-
44849094781
-
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
-
R. I. Morimoto, Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging. Genes Dev. 22, 1427-1438 (2008).
-
(2008)
Genes Dev.
, vol.22
, pp. 1427-1438
-
-
Morimoto, R.I.1
-
24
-
-
84861784690
-
SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage
-
Y. Yin, A. Seifert, J. S. Chua, J. F. Maure, F. Golebiowski, R. T. Hay, SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage. Genes Dev. 26, 1196-1208 (2012).
-
(2012)
Genes Dev.
, vol.26
, pp. 1196-1208
-
-
Yin, Y.1
Seifert, A.2
Chua, J.S.3
Maure, J.F.4
Golebiowski, F.5
Hay, R.T.6
-
25
-
-
53849146020
-
Model-based analysis of ChIP-Seq (MACS)
-
Y. Zhang, T. Liu, C. A. Meyer, J. Eeckhoute, D. S. Johnson, B. E. Bernstein, C. Nusbaum, R. M. Myers, M. Brown, W. Li, X. S. Liu, Model-based analysis of ChIP-Seq (MACS). Genome Biol. 9, R137 (2008).
-
(2008)
Genome Biol.
, vol.9
, pp. R137
-
-
Zhang, Y.1
Liu, T.2
Meyer, C.A.3
Eeckhoute, J.4
Johnson, D.S.5
Bernstein, B.E.6
Nusbaum, C.7
Myers, R.M.8
Brown, M.9
Li, W.10
Liu, X.S.11
-
26
-
-
84866127830
-
Identifying ChIP-seq enrichment using MACS
-
J. Feng, T. Liu, B. Qin, Y. Zhang, X. S. Liu, Identifying ChIP-seq enrichment using MACS. Nat. Protoc. 7, 1728-1740 (2012).
-
(2012)
Nat. Protoc.
, vol.7
, pp. 1728-1740
-
-
Feng, J.1
Liu, T.2
Qin, B.3
Zhang, Y.4
Liu, X.S.5
-
27
-
-
70450255284
-
PARP-1 transcriptional activity is regulated by sumoylation upon heat shock
-
N. Martin, K. Schwamborn, V. Schreiber, A. Werner, C. Guillier, X. D. Zhang, O. Bischof, J. S. Seeler, A. Dejean, PARP-1 transcriptional activity is regulated by sumoylation upon heat shock. EMBO J. 28, 3534-3548 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 3534-3548
-
-
Martin, N.1
Schwamborn, K.2
Schreiber, V.3
Werner, A.4
Guillier, C.5
Zhang, X.D.6
Bischof, O.7
Seeler, J.S.8
Dejean, A.9
-
28
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
R. E. Thurman, E. Rynes, R. Humbert, J. Vierstra, M. T. Maurano, E. Haugen, N. C. Sheffield, A. B. Stergachis, H. Wang, B. Vernot, K. Garg, S. John, R. Sandstrom, D. Bates, L. Boatman, T. K. Canfield, M. Diegel, D. Dunn, A. K. Ebersol, T. Frum, E. Giste, A. K. Johnson, E. M. Johnson, T. Kutyavin, B. Lajoie, B. K. Lee, K. Lee, D. London, D. Lotakis, S. Neph, F. Neri, E. D. Nguyen, H. Qu, A. P. Reynolds, V. Roach, A. Safi, M. E. Sanchez, A. Sanyal, A. Shafer, J. M. Simon, L. Song, S. Vong, M. Weaver, Y. Yan, Z. Zhang, B. Lenhard, M. Tewari, M. O. Dorschner, R. S. Hansen, P. A. Navas, G. Stamatoyannopoulos, V. R. Iyer, J. D. Lieb, S. R. Sunyaev, J. M. Akey, P. J. Sabo, R. Kaul, T. S. Furey, J. Dekker, G. E. Crawford, J. A. Stamatoyannopoulos, The accessible chromatin landscape of the human genome. Nature 489, 75-82 (2012).
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
Rynes, E.2
Humbert, R.3
Vierstra, J.4
Maurano, M.T.5
Haugen, E.6
Sheffield, N.C.7
Stergachis, A.B.8
Wang, H.9
Vernot, B.10
Garg, K.11
John, S.12
Sandstrom, R.13
Bates, D.14
Boatman, L.15
Canfield, T.K.16
Diegel, M.17
Dunn, D.18
Ebersol, A.K.19
Frum, T.20
Giste, E.21
Johnson, A.K.22
Johnson, E.M.23
Kutyavin, T.24
Lajoie, B.25
Lee, B.K.26
Lee, K.27
London, D.28
Lotakis, D.29
Neph, S.30
Neri, F.31
Nguyen, E.D.32
Qu, H.33
Reynolds, A.P.34
Roach, V.35
Safi, A.36
Sanchez, M.E.37
Sanyal, A.38
Shafer, A.39
Simon, J.M.40
Song, L.41
Vong, S.42
Weaver, M.43
Yan, Y.44
Zhang, Z.45
Lenhard, B.46
Tewari, M.47
Dorschner, M.O.48
Hansen, R.S.49
Navas, P.A.50
Stamatoyannopoulos, G.51
Iyer, V.R.52
Lieb, J.D.53
Sunyaev, S.R.54
Akey, J.M.55
Sabo, P.J.56
Kaul, R.57
Furey, T.S.58
Dekker, J.59
Crawford, G.E.60
Stamatoyannopoulos, J.A.61
more..
-
29
-
-
84857822152
-
An effective statistical evaluation of ChIPseq dataset similarity
-
M. D. Chikina, O. G. Troyanskaya, An effective statistical evaluation of ChIPseq dataset similarity. Bioinformatics 28, 607-613 (2012).
-
(2012)
Bioinformatics
, vol.28
, pp. 607-613
-
-
Chikina, M.D.1
Troyanskaya, O.G.2
-
30
-
-
30044449116
-
Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS)
-
G. E. Crawford, I. E. Holt, J. Whittle, B. D. Webb, D. Tai, S. Davis, E. H. Margulies, Y. Chen, J. A. Bernat, D. Ginsburg, D. Zhou, S. Luo, T. J. Vasicek, M. J. Daly, T. G. Wolfsberg, F. S. Collins, Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). Genome Res. 16, 123-131 (2006).
-
(2006)
Genome Res.
, vol.16
, pp. 123-131
-
-
Crawford, G.E.1
Holt, I.E.2
Whittle, J.3
Webb, B.D.4
Tai, D.5
Davis, S.6
Margulies, E.H.7
Chen, Y.8
Bernat, J.A.9
Ginsburg, D.10
Zhou, D.11
Luo, S.12
Vasicek, T.J.13
Daly, M.J.14
Wolfsberg, T.G.15
Collins, F.S.16
-
31
-
-
80053539409
-
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
-
L. Song, Z. Zhang, L. L. Grasfeder, A. P. Boyle, P. G. Giresi, B. K. Lee, N. C. Sheffield, S. Graf, M. Huss, D. Keefe, Z. Liu, D. London, R. M. McDaniell, Y. Shibata, K. A. Showers, J. M. Simon, T. Vales, T. Wang, D. Winter, Z. Zhang, N. D. Clarke, E. Birney, V. R. Iyer, G. E. Crawford, J. D. Lieb, T. S. Furey, Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. Genome Res. 21, 1757-1767 (2011).
-
(2011)
Genome Res.
, vol.21
, pp. 1757-1767
-
-
Song, L.1
Zhang, Z.2
Grasfeder, L.L.3
Boyle, A.P.4
Giresi, P.G.5
Lee, B.K.6
Sheffield, N.C.7
Graf, S.8
Huss, M.9
Keefe, D.10
Liu, Z.11
London, D.12
McDaniell, R.M.13
Shibata, Y.14
Showers, K.A.15
Simon, J.M.16
Vales, T.17
Wang, T.18
Winter, D.19
Zhang, Z.20
Clarke, N.D.21
Birney, E.22
Iyer, V.R.23
Crawford, G.E.24
Lieb, J.D.25
Furey, T.S.26
more..
-
32
-
-
84871750894
-
mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis
-
S. D. Chou, T. Prince, J. Gong, S. K. Calderwood, mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis. PLOS One 7, e39679 (2012).
-
(2012)
PLOS One
, vol.7
-
-
Chou, S.D.1
Prince, T.2
Gong, J.3
Calderwood, S.K.4
-
33
-
-
30444440554
-
PDSM, a motif for phosphorylation-dependent SUMO modification
-
V. Hietakangas, J. Anckar, H. A. Blomster, M. Fujimoto, J. J. Palvimo, A. Nakai, L. Sistonen, PDSM, a motif for phosphorylation-dependent SUMO modification. Proc. Natl. Acad. Sci. U.S.A. 103, 45-50 (2006).
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 45-50
-
-
Hietakangas, V.1
Anckar, J.2
Blomster, H.A.3
Fujimoto, M.4
Palvimo, J.J.5
Nakai, A.6
Sistonen, L.7
-
34
-
-
78649346692
-
The heat shock response: Life on the verge of death
-
K. Richter, M. Haslbeck, J. Buchner, The heat shock response: Life on the verge of death. Mol. Cell 40, 253-266 (2010).
-
(2010)
Mol. Cell
, vol.40
, pp. 253-266
-
-
Richter, K.1
Haslbeck, M.2
Buchner, J.3
-
35
-
-
0032535245
-
Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
-
R. I. Morimoto, Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev. 12, 3788-3796 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 3788-3796
-
-
Morimoto, R.I.1
-
36
-
-
20644448390
-
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors
-
K. M. Cheung, T. P. Matthews, K. James, M. G. Rowlands, K. J. Boxall, S. Y. Sharp, A. Maloney, S. M. Roe, C. Prodromou, L. H. Pearl, G. W. Aherne, E. McDonald, P. Workman, The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors. Bioorg. Med. Chem. Lett. 15, 3338-3343 (2005).
-
(2005)
Bioorg. Med. Chem. Lett.
, vol.15
, pp. 3338-3343
-
-
Cheung, K.M.1
Matthews, T.P.2
James, K.3
Rowlands, M.G.4
Boxall, K.J.5
Sharp, S.Y.6
Maloney, A.7
Roe, S.M.8
Prodromou, C.9
Pearl, L.H.10
Aherne, G.W.11
McDonald, E.12
Workman, P.13
-
37
-
-
0031875042
-
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin
-
T. W. Schulte, L. M. Neckers, The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin. Cancer Chemother. Pharmacol. 42, 273-279 (1998).
-
(1998)
Cancer Chemother. Pharmacol.
, vol.42
, pp. 273-279
-
-
Schulte, T.W.1
Neckers, L.M.2
-
38
-
-
61849170193
-
Genome-wide profiling of salt fractions maps physical properties of chromatin
-
S. Henikoff, J. G. Henikoff, A. Sakai, G. B. Loeb, K. Ahmad, Genome-wide profiling of salt fractions maps physical properties of chromatin. Genome Res. 19, 460-469 (2009).
-
(2009)
Genome Res.
, vol.19
, pp. 460-469
-
-
Henikoff, S.1
Henikoff, J.G.2
Sakai, A.3
Loeb, G.B.4
Ahmad, K.5
-
39
-
-
84885066285
-
Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation
-
H. Neyret-Kahn, M. Benhamed, T. Ye, S. Le Gras, J. C. Cossec, P. Lapaquette, O. Bischof, M. Ouspenskaia, M. Dasso, J. Seeler, I. Davidson, A. Dejean, Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation. Genome Res. 23, 1563-1579 (2013).
-
(2013)
Genome Res.
, vol.23
, pp. 1563-1579
-
-
Neyret-Kahn, H.1
Benhamed, M.2
Ye, T.3
Le Gras, S.4
Cossec, J.C.5
Lapaquette, P.6
Bischof, O.7
Ouspenskaia, M.8
Dasso, M.9
Seeler, J.10
Davidson, I.11
Dejean, A.12
-
40
-
-
77954955686
-
Heat shock factors: Integrators of cell stress, development and lifespan
-
M. Akerfelt, R. I. Morimoto, L. Sistonen, Heat shock factors: Integrators of cell stress, development and lifespan. Nat. Rev. Mol. Cell Biol. 11, 545-555 (2010).
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 545-555
-
-
Akerfelt, M.1
Morimoto, R.I.2
Sistonen, L.3
-
41
-
-
0034069656
-
Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway
-
L. Pirkkala, T. P. Alastalo, X. Zuo, I. J. Benjamin, L. Sistonen, Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway. Mol. Cell. Biol. 20, 2670-2675 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2670-2675
-
-
Pirkkala, L.1
Alastalo, T.P.2
Zuo, X.3
Benjamin, I.J.4
Sistonen, L.5
-
42
-
-
84934440933
-
Chaperone regulation of the heat shock protein response
-
R. Voellmy, F. Boellmann, Chaperone regulation of the heat shock protein response. Adv. Exp. Med. Biol. 594, 89-99 (2007).
-
(2007)
Adv. Exp. Med. Biol.
, vol.594
, pp. 89-99
-
-
Voellmy, R.1
Boellmann, F.2
-
43
-
-
4744360999
-
A proteome-wide approach identifies sumoylated substrate proteins in yeast
-
V. G. Panse, U. Hardeland, T. Werner, B. Kuster, E. Hurt, A proteome-wide approach identifies sumoylated substrate proteins in yeast. J. Biol. Chem. 279, 41346-41351 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41346-41351
-
-
Panse, V.G.1
Hardeland, U.2
Werner, T.3
Kuster, B.4
Hurt, E.5
-
44
-
-
8544273758
-
Global analysis of protein sumoylation in Saccharomyces cerevisiae
-
J. A. Wohlschlegel, E. S. Johnson, S. I. Reed, J. R. Yates III, Global analysis of protein sumoylation in Saccharomyces cerevisiae. J. Biol. Chem. 279, 45662-45668 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 45662-45668
-
-
Wohlschlegel, J.A.1
Johnson, E.S.2
Reed, S.I.3
Yates, J.R.4
-
45
-
-
84869091913
-
Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair
-
I. Psakhye, S. Jentsch, Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair. Cell 151, 807-820 (2012).
-
(2012)
Cell
, vol.151
, pp. 807-820
-
-
Psakhye, I.1
Jentsch, S.2
-
46
-
-
84899759007
-
Proteome-wide identification of SUMO2 modification sites
-
T. Tammsalu, I. Matic, E. G. Jaffray, A. F. Ibrahim, M. H. Tatham, R. T. Hay, Proteome-wide identification of SUMO2 modification sites. Sci. Signal. 7, rs2 (2014).
-
(2014)
Sci. Signal.
, vol.7
, pp. rs2
-
-
Tammsalu, T.1
Matic, I.2
Jaffray, E.G.3
Ibrahim, A.F.4
Tatham, M.H.5
Hay, R.T.6
-
47
-
-
33748574525
-
Formation and nuclear export of preribosomes are functionally linked to the smallubiquitin-related modifier pathway
-
V. G. Panse, D. Kressler, A. Pauli, E. Petfalski, M. Gnadig, D. Tollervey, E. Hurt, Formation and nuclear export of preribosomes are functionally linked to the smallubiquitin-related modifier pathway. Traffic 7, 1311-1321 (2006).
-
(2006)
Traffic
, vol.7
, pp. 1311-1321
-
-
Panse, V.G.1
Kressler, D.2
Pauli, A.3
Petfalski, E.4
Gnadig, M.5
Tollervey, D.6
Hurt, E.7
-
48
-
-
79952756302
-
The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex
-
E. Finkbeiner, M. Haindl, S. Muller, The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. EMBO J. 30, 1067-1078 (2011).
-
(2011)
EMBO J.
, vol.30
, pp. 1067-1078
-
-
Finkbeiner, E.1
Haindl, M.2
Muller, S.3
-
49
-
-
84884966441
-
SUMOylation is essential for sex-specific assembly and function of the Caenorhabditis elegans dosage compensation complex on X chromosomes
-
R. R. Pferdehirt, B. J. Meyer, SUMOylation is essential for sex-specific assembly and function of the Caenorhabditis elegans dosage compensation complex on X chromosomes. Proc. Natl. Acad. Sci. U.S.A. 110, E3810-E3819 (2013).
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. E3810-E3819
-
-
Pferdehirt, R.R.1
Meyer, B.J.2
-
50
-
-
84882738244
-
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites
-
J. Yan, M. Enge, T. Whitington, K. Dave, J. Liu, I. Sur, B. Schmierer, A. Jolma, T. Kivioja, M. Taipale, J. Taipale, Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites. Cell 154, 801-813 (2013).
-
(2013)
Cell
, vol.154
, pp. 801-813
-
-
Yan, J.1
Enge, M.2
Whitington, T.3
Dave, K.4
Liu, J.5
Sur, I.6
Schmierer, B.7
Jolma, A.8
Kivioja, T.9
Taipale, M.10
Taipale, J.11
-
51
-
-
84872051865
-
Histone chaperones in nucleosome assembly and human disease
-
R. J. Burgess, Z. Zhang, Histone chaperones in nucleosome assembly and human disease. Nat. Struct. Mol. Biol. 20, 14-22 (2013).
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 14-22
-
-
Burgess, R.J.1
Zhang, Z.2
-
53
-
-
78650250161
-
Recruitment timing and dynamics of transcription factors at the Hsp70 loci in living cells
-
K. L. Zobeck, M. S. Buckley, W. R. Zipfel, J. T. Lis, Recruitment timing and dynamics of transcription factors at the Hsp70 loci in living cells. Mol. Cell 40, 965-975 (2010).
-
(2010)
Mol. Cell
, vol.40
, pp. 965-975
-
-
Zobeck, K.L.1
Buckley, M.S.2
Zipfel, W.R.3
Lis, J.T.4
-
54
-
-
84896719951
-
Polyphosphate is a primordial chaperone
-
M. J. Gray, W. Y. Wholey, N. O. Wagner, C. M. Cremers, A. Mueller-Schickert, N. T. Hock, A. G. Krieger, E. M. Smith, R. A. Bender, J. C. Bardwell, U. Jakob, Polyphosphate is a primordial chaperone. Mol. Cell 53, 689-699 (2014).
-
(2014)
Mol. Cell
, vol.53
, pp. 689-699
-
-
Gray, M.J.1
Wholey, W.Y.2
Wagner, N.O.3
Cremers, C.M.4
Mueller-Schickert, A.5
Hock, N.T.6
Krieger, A.G.7
Smith, E.M.8
Bender, R.A.9
Bardwell, J.C.10
Jakob, U.11
-
55
-
-
84898605418
-
N-terminal protein tails act as aggregation protective entropic bristles: The SUMO case
-
R. Graña-Montes, P. Marinelli, D. Reverter, S. Ventura, N-terminal protein tails act as aggregation protective entropic bristles: The SUMO case. Biomacromolecules 15, 1194-1203 (2014).
-
(2014)
Biomacromolecules
, vol.15
, pp. 1194-1203
-
-
Graña-Montes, R.1
Marinelli, P.2
Reverter, D.3
Ventura, S.4
-
56
-
-
50649118115
-
High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay
-
L. Dölken, Z. Ruzsics, B. Radle, C. C. Friedel, R. Zimmer, J. Mages, R. Hoffmann, P. Dickinson, T. Forster, P. Ghazal, U. H. Koszinowski, High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay. RNA 14, 1959-1972 (2008).
-
(2008)
RNA
, vol.14
, pp. 1959-1972
-
-
Dölken, L.1
Ruzsics, Z.2
Radle, B.3
Friedel, C.C.4
Zimmer, R.5
Mages, J.6
Hoffmann, R.7
Dickinson, P.8
Forster, T.9
Ghazal, P.10
Koszinowski, U.H.11
-
57
-
-
78651084831
-
The SUMO protease SENP6 is a direct regulator of PML nuclear bodies
-
N. Hattersley, L. Shen, E. G. Jaffray, R. T. Hay, The SUMO protease SENP6 is a direct regulator of PML nuclear bodies. Mol. Biol. Cell 22, 78-90 (2011).
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 78-90
-
-
Hattersley, N.1
Shen, L.2
Jaffray, E.G.3
Hay, R.T.4
-
58
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
R. C. Gentleman, V. J. Carey, D. M. Bates, B. Bolstad, M. Dettling, S. Dudoit, B. Ellis, L. Gautier, Y. Ge, J. Gentry, K. Hornik, T. Hothorn, W. Huber, S. Iacus, R. Irizarry, F. Leisch, C. Li, M. Maechler, A. J. Rossini, G. Sawitzki, C. Smith, G. Smyth, L. Tierney, J. Y. Yang, J. Zhang, Bioconductor: Open software development for computational biology and bioinformatics. Genome Biol. 5, R80 (2004).
-
(2004)
Genome Biol.
, vol.5
, pp. R80
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
Bolstad, B.4
Dettling, M.5
Dudoit, S.6
Ellis, B.7
Gautier, L.8
Ge, Y.9
Gentry, J.10
Hornik, K.11
Hothorn, T.12
Huber, W.13
Iacus, S.14
Irizarry, R.15
Leisch, F.16
Li, C.17
Maechler, M.18
Rossini, A.J.19
Sawitzki, G.20
Smith, C.21
Smyth, G.22
Tierney, L.23
Yang, J.Y.24
Zhang, J.25
more..
-
59
-
-
84878580738
-
The Subread aligner: Fast, accurate and scalable read mapping by seed-and-vote
-
Y. Liao, G. K. Smyth, W. Shi, The Subread aligner: Fast, accurate and scalable read mapping by seed-and-vote. Nucleic Acids Res. 41, e108 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. e108
-
-
Liao, Y.1
Smyth, G.K.2
Shi, W.3
-
60
-
-
77951947707
-
ChIPpeakAnno: A Bioconductor package to annotate ChIP-seq and ChIP-chip data
-
L. J. Zhu, C. Gazin, N. D. Lawson, H. Pagès, S. M. Lin, D. S. Lapointe, M. R. Green, ChIPpeakAnno: A Bioconductor package to annotate ChIP-seq and ChIP-chip data. BMC Bioinformatics 11, 237 (2010).
-
(2010)
BMC Bioinformatics
, vol.11
, pp. 237
-
-
Zhu, L.J.1
Gazin, C.2
Lawson, N.D.3
Pagès, H.4
Lin, S.M.5
Lapointe, D.S.6
Green, M.R.7
-
61
-
-
84875945705
-
ENCODE data in the UCSC Genome Browser: Year 5 update
-
K. R. Rosenbloom, C. A. Sloan, V. S. Malladi, T. R. Dreszer, K. Learned, V. M. Kirkup, M. C. Wong, M. Maddren, R. Fang, S. G. Heitner, B. T. Lee, G. P. Barber, R. A. Harte, M. Diekhans, J. C. Long, S. P. Wilder, A. S. Zweig, D. Karolchik, R. M. Kuhn, D. Haussler, W. J. Kent, ENCODE data in the UCSC Genome Browser: Year 5 update. Nucleic Acids Res. 41, D56-D63 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D56-D63
-
-
Rosenbloom, K.R.1
Sloan, C.A.2
Malladi, V.S.3
Dreszer, T.R.4
Learned, K.5
Kirkup, V.M.6
Wong, M.C.7
Maddren, M.8
Fang, R.9
Heitner, S.G.10
Lee, B.T.11
Barber, G.P.12
Harte, R.A.13
Diekhans, M.14
Long, J.C.15
Wilder, S.P.16
Zweig, A.S.17
Karolchik, D.18
Kuhn, R.M.19
Haussler, D.20
Kent, W.J.21
more..
-
62
-
-
84876996918
-
TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
-
D. Kim, G. Pertea, C. Trapnell, H. Pimentel, R. Kelley, S. L. Salzberg, TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol. 14, R36 (2013).
-
(2013)
Genome Biol.
, vol.14
, pp. R36
-
-
Kim, D.1
Pertea, G.2
Trapnell, C.3
Pimentel, H.4
Kelley, R.5
Salzberg, S.L.6
-
63
-
-
77958471357
-
Differential expression analysis for sequence count data
-
S. Anders, W. Huber, Differential expression analysis for sequence count data. Genome Biol. 11, R106 (2010).
-
(2010)
Genome Biol.
, vol.11
, pp. R106
-
-
Anders, S.1
Huber, W.2
|