메뉴 건너뛰기




Volumn 5, Issue , 2015, Pages

Increased neurokinin-1 receptor availability in the amygdala in social anxiety disorder: A positron emission tomography study with [11C]GR205171

Author keywords

[No Author keywords available]

Indexed keywords

NEUROKININ 1 RECEPTOR; TRACER; NEUROKININ 1 RECEPTOR ANTAGONIST; PIPERIDINE DERIVATIVE; TETRAZOLE DERIVATIVE; VOFOPITANT;

EID: 84936875113     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2015.92     Document Type: Article
Times cited : (20)

References (66)
  • 1
    • 72049085534 scopus 로고    scopus 로고
    • The neurocircuitry of fear, stress, and anxiety disorders
    • Shin LM, Liberzon I. The neurocircuitry of fear, stress, and anxiety disorders. Neuropsychopharmacology 2010; 35: 169-191.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 169-191
    • Shin, L.M.1    Liberzon, I.2
  • 2
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication
    • Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication. Arch Gen Psychiatry 2005; 62: 593-602.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Merikangas, K.R.5    Walters, E.E.6
  • 3
    • 0026405544 scopus 로고
    • Molecular characterization of the three tachykinin receptors
    • Ohkubo H, Nakanishi S. Molecular characterization of the three tachykinin receptors. Ann N Y Acad Sci 1991; 632: 53-62.
    • (1991) Ann N Y Acad Sci , vol.632 , pp. 53-62
    • Ohkubo, H.1    Nakanishi, S.2
  • 4
    • 84944496221 scopus 로고
    • An unidentified depressor substance in certain tissue extracts
    • Von Euler US, Gaddum JH. An unidentified depressor substance in certain tissue extracts. J Physiol 1931; 72: 74-87.
    • (1931) J Physiol , vol.72 , pp. 74-87
    • Von Euler, U.S.1    Gaddum, J.H.2
  • 5
    • 0033745545 scopus 로고    scopus 로고
    • Neuroanatomical localisation of substance P in the CNS and sensory neurons
    • Ribeiro-da-Silva A, Hökfelt T. Neuroanatomical localisation of substance P in the CNS and sensory neurons. Neuropeptides 2000; 34: 256-271.
    • (2000) Neuropeptides , vol.34 , pp. 256-271
    • Ribeiro-da-Silva, A.1    Hökfelt, T.2
  • 6
    • 33749556143 scopus 로고    scopus 로고
    • The role of substance P in stress and anxiety responses
    • Ebner K, Singewald N. The role of substance P in stress and anxiety responses. Amino Acids 2006; 31: 251-272.
    • (2006) Amino Acids , vol.31 , pp. 251-272
    • Ebner, K.1    Singewald, N.2
  • 7
    • 43949121774 scopus 로고    scopus 로고
    • Recent advances in the neurobiology of anxiety disorders: Implications for novel therapeutics
    • Mathew SJ, Price RB, Charney DS. Recent advances in the neurobiology of anxiety disorders: implications for novel therapeutics. Am J Med Genet 2008; 148C:89-98.
    • (2008) Am J Med Genet , vol.148 C , pp. 89-98
    • Mathew, S.J.1    Price, R.B.2    Charney, D.S.3
  • 9
    • 1642488331 scopus 로고    scopus 로고
    • Substance P in the medial amygdala: Emotional stress-sensitive release and modulation of anxiety-related behavior in rats
    • Ebner K, Rupniak NM, Saria A, Singewald N. Substance P in the medial amygdala: emotional stress-sensitive release and modulation of anxiety-related behavior in rats. Proc Natl Acad Sci USA 2004; 101: 4280-4285.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4280-4285
    • Ebner, K.1    Rupniak, N.M.2    Saria, A.3    Singewald, N.4
  • 10
    • 85047696280 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid substance P concentrations in posttraumatic stress disorder and major depression
    • Geracioti TD Jr, Carpenter LL, Owens MJ, Baker DG, Ekhator NN, Horn PS et al. Elevated cerebrospinal fluid substance P concentrations in posttraumatic stress disorder and major depression. Am J Psychiatry 2006; 163: 637-643.
    • (2006) Am J Psychiatry , vol.163 , pp. 637-643
    • Geracioti, T.D.1    Carpenter, L.L.2    Owens, M.J.3    Baker, D.G.4    Ekhator, N.N.5    Horn, P.S.6
  • 11
    • 33947590288 scopus 로고    scopus 로고
    • Symptom provocation in specific phobia affects the substance P neurokinin-1 receptor system
    • Michelgård Å, Appel L, Pissiota A, Frans O¨, Långström B, Bergström et al. Symptom provocation in specific phobia affects the substance P neurokinin-1 receptor system. Biol Psychiatry 2007; 61: 1002-1006.
    • (2007) Biol Psychiatry , vol.61 , pp. 1002-1006
    • Michelgård, Å.1    Appel, L.2    Pissiota, A.3    Frans, O¨.4    Långström, B.5    Bergström6
  • 12
    • 84898997826 scopus 로고    scopus 로고
    • Effects of substance P and Sar-Met-SP, a NK1 agonist, in distinct amygdaloid nuclei on anxiety-like behavior in rats
    • Bassi GS, de Carvalho MC, Brandão ML. Effects of substance P and Sar-Met-SP, a NK1 agonist, in distinct amygdaloid nuclei on anxiety-like behavior in rats. Neurosci Lett 2014; 569: 121-125.
    • (2014) Neurosci Lett , vol.569 , pp. 121-125
    • Bassi, G.S.1    De Carvalho, M.C.2    Brandão, M.L.3
  • 14
    • 22444442937 scopus 로고    scopus 로고
    • Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram, or placebo
    • Furmark T, Appel L, Michelgård Å, Wahlstedt K, Åhs F, Zancan S et al. Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram, or placebo. Biol Psychiatry 2005; 58: 132-142.
    • (2005) Biol Psychiatry , vol.58 , pp. 132-142
    • Furmark, T.1    Appel, L.2    Michelgård, Å.3    Wahlstedt, K.4    Åhs, F.5    Zancan, S.6
  • 15
    • 0032508514 scopus 로고    scopus 로고
    • Distinct mechanism for antidepressant activity by blockade of central substance P receptors
    • Kramer MS, Cutler N, Feighner J, Shrivastava R, Carman J, Sramek JJ et al. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 1998; 281: 1640-1645.
    • (1998) Science , vol.281 , pp. 1640-1645
    • Kramer, M.S.1    Cutler, N.2    Feighner, J.3    Shrivastava, R.4    Carman, J.5    Sramek, J.J.6
  • 16
    • 32144442187 scopus 로고    scopus 로고
    • Lack of efficacy of the substance P (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder
    • Keller M, Montgomery S, Ball W, Morrison M, Snavely D, Liu G et al. Lack of efficacy of the substance P (neurokinin1 receptor) antagonist aprepitant in the treatment of major depressive disorder. Biol Psychiatry 2006; 59: 216-223.
    • (2006) Biol Psychiatry , vol.59 , pp. 216-223
    • Keller, M.1    Montgomery, S.2    Ball, W.3    Morrison, M.4    Snavely, D.5    Liu, G.6
  • 18
    • 84871485341 scopus 로고    scopus 로고
    • Lack of efficacy of L-759274, a novel neurokinin 1 (substance P) receptor antagonist, for the treatment of generalized anxiety disorder
    • Michelson D, Hargreaves R, Alexander R, Ceesay P, Hietala J, Lines C et al. Lack of efficacy of L-759274, a novel neurokinin 1 (substance P) receptor antagonist, for the treatment of generalized anxiety disorder. Int J Neuropsychopharmacol 2013; 16: 1-11.
    • (2013) Int J Neuropsychopharmacol , vol.16 , pp. 1-11
    • Michelson, D.1    Hargreaves, R.2    Alexander, R.3    Ceesay, P.4    Hietala, J.5    Lines, C.6
  • 19
    • 79251640951 scopus 로고    scopus 로고
    • A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trial
    • Mathew SJ, Vythilingam M, Murrough JW, Zarate CA Jr., Feder A, Luckenbaugh DA et al. A selective neurokinin-1 receptor antagonist in chronic PTSD: a randomized, double-blind, placebo-controlled, proof-of-concept trial. Eur Neuropsychopharmacol 2011; 21: 221-229.
    • (2011) Eur Neuropsychopharmacol , vol.21 , pp. 221-229
    • Mathew, S.J.1    Vythilingam, M.2    Murrough, J.W.3    Zarate, C.A.4    Feder, A.5    Luckenbaugh, D.A.6
  • 20
    • 10744227469 scopus 로고    scopus 로고
    • Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression
    • Kramer MS, Winokur A, Kelsey J, Preskorn SH, Rothschild AJ, Snavely D et al. Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression. Neuropsychopharmacology 2004; 29: 385-392.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 385-392
    • Kramer, M.S.1    Winokur, A.2    Kelsey, J.3    Preskorn, S.H.4    Rothschild, A.J.5    Snavely, D.6
  • 21
    • 67349222818 scopus 로고    scopus 로고
    • Decreased neurokinin-1 (substance P) receptor binding in patients with panic disorder: Positron emission tomographic study with [18F]SPA-RQ
    • Fujimura Y, Yasuno F, Farris A, Liow J-S, Geraci M, Drevets W et al. Decreased neurokinin-1 (substance P) receptor binding in patients with panic disorder: positron emission tomographic study with [18F]SPA-RQ. Biol Psychiatry 2009; 66: 94-97.
    • (2009) Biol Psychiatry , vol.66 , pp. 94-97
    • Fujimura, Y.1    Yasuno, F.2    Farris, A.3    Liow, J.-S.4    Geraci, M.5    Drevets, W.6
  • 23
    • 84907707155 scopus 로고    scopus 로고
    • Neuroimaging in social anxiety disorder - A meta-analytic review resulting in a new neurofunctional model
    • Brühl AB, Delsignore A, Komossa K, Weidt S. Neuroimaging in social anxiety disorder - A meta-analytic review resulting in a new neurofunctional model. Neurosci Biobehav Rev 2014; 47: 260-280.
    • (2014) Neurosci Biobehav Rev , vol.47 , pp. 260-280
    • Brühl, A.B.1    Delsignore, A.2    Komossa, K.3    Weidt, S.4
  • 24
    • 0033983766 scopus 로고    scopus 로고
    • Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171 - PET studies in rhesus monkey
    • Bergström M, Fasth K-J, Kilpatrick G, Ward P, Cable KM, Wipperman MD et al. Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171 - PET studies in rhesus monkey. Neuropharmacology 2000; 39: 664-670.
    • (2000) Neuropharmacology , vol.39 , pp. 664-670
    • Bergström, M.1    Fasth, K.-J.2    Kilpatrick, G.3    Ward, P.4    Cable, K.M.5    Wipperman, M.D.6
  • 26
    • 0032421570 scopus 로고    scopus 로고
    • The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
    • Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998; 59: 22-33.
    • (1998) J Clin Psychiatry , vol.59 , pp. 22-33
    • Sheehan, D.V.1    Lecrubier, Y.2    Sheehan, K.H.3    Amorim, P.4    Janavs, J.5    Weiller, E.6
  • 28
    • 0034910886 scopus 로고    scopus 로고
    • The Liebowitz social anxiety scale: A comparison of the psychometric properties of self-report and clinician-administered formats
    • Fresco DM, Coles ME, Heimberg RG, Liebowitz MR, Hami S, Stein MB et al. The Liebowitz social anxiety scale: a comparison of the psychometric properties of self-report and clinician-administered formats. Psychol Med 2001; 31: 1025-1035.
    • (2001) Psychol Med , vol.31 , pp. 1025-1035
    • Fresco, D.M.1    Coles, M.E.2    Heimberg, R.G.3    Liebowitz, M.R.4    Hami, S.5    Stein, M.B.6
  • 29
    • 33646399434 scopus 로고    scopus 로고
    • [3H]GR205171 displays similar NK1 receptor binding profile in gerbil and human brain
    • Griffante C, Carletti R, Andreetta F, Corsi M. [3H]GR205171 displays similar NK1 receptor binding profile in gerbil and human brain. Br J Pharmacol 2006; 148: 39-45.
    • (2006) Br J Pharmacol , vol.148 , pp. 39-45
    • Griffante, C.1    Carletti, R.2    Andreetta, F.3    Corsi, M.4
  • 30
    • 0030603866 scopus 로고    scopus 로고
    • GR205171: A novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity
    • Gardner CJ, Armour DR, Beattie DT, Gale JD, Hawcock AB, Kilpatrick GJ et al. GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity. Regul Pept 1996; 65: 45-53.
    • (1996) Regul Pept , vol.65 , pp. 45-53
    • Gardner, C.J.1    Armour, D.R.2    Beattie, D.T.3    Gale, J.D.4    Hawcock, A.B.5    Kilpatrick, G.J.6
  • 32
    • 0020956774 scopus 로고
    • Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data
    • Patlak CS, Blasberg RG, Fenstermacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 1983; 3: 1-7.
    • (1983) J Cereb Blood Flow Metab , vol.3 , pp. 1-7
    • Patlak, C.S.1    Blasberg, R.G.2    Fenstermacher, J.D.3
  • 34
    • 12844261790 scopus 로고    scopus 로고
    • MR-based automatic delineation of volumes of interest in human brain PET images using probability maps
    • Svarer C, Madsen K, Hasselbalch SG, Pinborg LH, Haugbøl S, Frøkjaer VG et al. MR-based automatic delineation of volumes of interest in human brain PET images using probability maps. Neuroimage 2005; 24: 969-979.
    • (2005) Neuroimage , vol.24 , pp. 969-979
    • Svarer, C.1    Madsen, K.2    Hasselbalch, S.G.3    Pinborg, L.H.4    Haugbøl, S.5    Frøkjaer, V.G.6
  • 35
    • 0041669248 scopus 로고    scopus 로고
    • An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets
    • Maldjian JA, Laurienti PJ, Kraft RA, Burdette JH. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 2003; 19: 1233-1239.
    • (2003) Neuroimage , vol.19 , pp. 1233-1239
    • Maldjian, J.A.1    Laurienti, P.J.2    Kraft, R.A.3    Burdette, J.H.4
  • 36
    • 84864152271 scopus 로고    scopus 로고
    • Age, sex and NK1 receptors in the human brain - A positron emission tomography study with [11C] GR205171
    • Engman J, Åhs F, Furmark T, Linnman C, Pissiota A, Appel L et al. Age, sex and NK1 receptors in the human brain - A positron emission tomography study with [11C] GR205171. Eur Neuropsychopharmacol 2012; 22: 562-568.
    • (2012) Eur Neuropsychopharmacol , vol.22 , pp. 562-568
    • Engman, J.1    Åhs, F.2    Furmark, T.3    Linnman, C.4    Pissiota, A.5    Appel, L.6
  • 37
    • 33847033376 scopus 로고    scopus 로고
    • Gender and age affect NK1 receptors in the human brain - A positron emission tomography study with [18F]SPA-RQ
    • Nyman MJ, Eskola O, Kajander J, Vahlberg T, Sanabria S, Burns D et al. Gender and age affect NK1 receptors in the human brain - a positron emission tomography study with [18F]SPA-RQ. Int J Neuropsychopharmacol 2007; 10: 219-229.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 219-229
    • Nyman, M.J.1    Eskola, O.2    Kajander, J.3    Vahlberg, T.4    Sanabria, S.5    Burns, D.6
  • 38
    • 50849110478 scopus 로고    scopus 로고
    • Modulation of basal and stress-induced amygdaloid substance P release by the potent and selective NK1 receptor antagonist L-822429
    • Singewald N, Chicchi GG, Thurner CC, Tsao K-L, Spetea M, Schmidhammer H et al. Modulation of basal and stress-induced amygdaloid substance P release by the potent and selective NK1 receptor antagonist L-822429. J Neurochem 2008; 106: 2476-2488.
    • (2008) J Neurochem , vol.106 , pp. 2476-2488
    • Singewald, N.1    Chicchi, G.G.2    Thurner, C.C.3    Tsao, K.-L.4    Spetea, M.5    Schmidhammer, H.6
  • 39
    • 84875464917 scopus 로고    scopus 로고
    • In search of the trauma memory: A meta-analysis of functional neuroimaging studies of symptom provocation in posttraumatic stress disorder (PTSD)
    • Sartory G, Cwik J, Knuppertz H, Schürholt B, Lebens M, Seitz RJ et al. In search of the trauma memory: a meta-analysis of functional neuroimaging studies of symptom provocation in posttraumatic stress disorder (PTSD). PLoS One 2013; 8: e58150.
    • (2013) PLoS One , vol.8
    • Sartory, G.1    Cwik, J.2    Knuppertz, H.3    Schürholt, B.4    Lebens, M.5    Seitz, R.J.6
  • 40
    • 84880278239 scopus 로고    scopus 로고
    • Meta-analysis of functional brain imaging in specific phobia
    • Ipser JC, Singh L, Stein DJ. Meta-analysis of functional brain imaging in specific phobia. Psychiatry Clin Neurosci 2013; 67: 311-322.
    • (2013) Psychiatry Clin Neurosci , vol.67 , pp. 311-322
    • Ipser, J.C.1    Singh, L.2    Stein, D.J.3
  • 41
    • 84934768193 scopus 로고    scopus 로고
    • The neurokinin-1 receptor antagonist aprepitant in co-morbid alcohol dependence and posttraumatic stress disorder: A human experimental study
    • Kwako LE, George DT, Schwandt ML, Spagnolo PA, Momenan R, Hommer DW et al. The neurokinin-1 receptor antagonist aprepitant in co-morbid alcohol dependence and posttraumatic stress disorder: a human experimental study. Psychopharmacology 2015; 232: 295-304.
    • (2015) Psychopharmacology , vol.232 , pp. 295-304
    • Kwako, L.E.1    George, D.T.2    Schwandt, M.L.3    Spagnolo, P.A.4    Momenan, R.5    Hommer, D.W.6
  • 42
    • 78851471555 scopus 로고    scopus 로고
    • Emotional processing in anterior cingulate and medial prefrontal cortex
    • Etkin A, Egner T, Kalisch R. Emotional processing in anterior cingulate and medial prefrontal cortex. Trends Cogn Sci 2011; 15: 85-93.
    • (2011) Trends Cogn Sci , vol.15 , pp. 85-93
    • Etkin, A.1    Egner, T.2    Kalisch, R.3
  • 43
    • 84920930228 scopus 로고    scopus 로고
    • Ventromedial prefrontal cortex is critical for the regulation of amygdala activity in humans
    • Motzkin JC, Philippi CL, Wolf RC, Baskaya MK, Koenigs M. Ventromedial prefrontal cortex is critical for the regulation of amygdala activity in humans. Biol Psychiatry 2015; 77: 276-284.
    • (2015) Biol Psychiatry , vol.77 , pp. 276-284
    • Motzkin, J.C.1    Philippi, C.L.2    Wolf, R.C.3    Baskaya, M.K.4    Koenigs, M.5
  • 44
    • 35748963237 scopus 로고    scopus 로고
    • Functional neuroimaging of anxiety: A meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia
    • Etkin A, Wager TD. Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Am J Psychiatry 2007; 164: 1476-1488.
    • (2007) Am J Psychiatry , vol.164 , pp. 1476-1488
    • Etkin, A.1    Wager, T.D.2
  • 45
    • 79958078919 scopus 로고    scopus 로고
    • NK1 receptor antagonism and the neural processing of emotional information in healthy volunteers
    • McCabe C, Cowen PJ, Harmer CJ. NK1 receptor antagonism and the neural processing of emotional information in healthy volunteers. Int J Neuropsychopharmacol 2009; 12: 1261-1274.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 1261-1274
    • McCabe, C.1    Cowen, P.J.2    Harmer, C.J.3
  • 46
    • 44149106395 scopus 로고    scopus 로고
    • Increased serotonin and dopamine transporter binding in psychotropic medication-naive patients with generalized social anxiety disorder shown by 123I-beta-(4-iodophenyl)-tropane SPECT
    • Van der Wee NJ, van Veen JF, Stevens H, van Vliet IM, van Rijk PP, Westenberg HG. Increased serotonin and dopamine transporter binding in psychotropic medication-naive patients with generalized social anxiety disorder shown by 123I-beta-(4-iodophenyl)-tropane SPECT. J Nucl Med 2008; 49: 757-763.
    • (2008) J Nucl Med , vol.49 , pp. 757-763
    • Van Der Wee, N.J.1    Van Veen, J.F.2    Stevens, H.3    Van Vliet, I.M.4    Van Rijk, P.P.5    Westenberg, H.G.6
  • 47
    • 79955698188 scopus 로고    scopus 로고
    • Gender differences in brain serotonin transporter availability in panic disorder
    • Maron E, Tõru I, Hirvonen J, Tuominen L, Lumme V, Vasar V et al. Gender differences in brain serotonin transporter availability in panic disorder. J Psychopharmacol 2011; 25: 952-959.
    • (2011) J Psychopharmacol , vol.25 , pp. 952-959
    • Maron, E.1    Tõru, I.2    Hirvonen, J.3    Tuominen, L.4    Lumme, V.5    Vasar, V.6
  • 50
    • 80755175887 scopus 로고    scopus 로고
    • Results from 2 randomized, double-blind, placebo-controlled studies of the novel NK1 receptor antagonist casopitant in patients with major depressive disorder
    • Ratti E, Bellew K, Bettica P, Bryson H, Zamuner S, Archer G et al. Results from 2 randomized, double-blind, placebo-controlled studies of the novel NK1 receptor antagonist casopitant in patients with major depressive disorder. J Clin Psychopharmacol 2011; 31: 727-733.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 727-733
    • Ratti, E.1    Bellew, K.2    Bettica, P.3    Bryson, H.4    Zamuner, S.5    Archer, G.6
  • 51
    • 84907164744 scopus 로고    scopus 로고
    • The neurokinin-1 receptor in addictive processes
    • Schank JR. The neurokinin-1 receptor in addictive processes. J Pharmacol Exp Ther 2014; 351: 2-8.
    • (2014) J Pharmacol Exp Ther , vol.351 , pp. 2-8
    • Schank, J.R.1
  • 52
    • 40849106521 scopus 로고    scopus 로고
    • Neurokinin 1 receptor antagonism as a possible therapy for alcoholism
    • George DT, Gilman J, Hersh J, Thorsell A, Herion D, Geyer C et al. Neurokinin 1 receptor antagonism as a possible therapy for alcoholism. Science 2008; 319: 1536-1539.
    • (2008) Science , vol.319 , pp. 1536-1539
    • George, D.T.1    Gilman, J.2    Hersh, J.3    Thorsell, A.4    Herion, D.5    Geyer, C.6
  • 53
    • 33644823142 scopus 로고    scopus 로고
    • Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: Results from the national epidemiologic survey on alcohol and related conditions
    • Conway KP, Compton W, Stinson FS, Grant BF. Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the national epidemiologic survey on alcohol and related conditions. J Clin Psychiatry 2006; 67: 247-258.
    • (2006) J Clin Psychiatry , vol.67 , pp. 247-258
    • Conway, K.P.1    Compton, W.2    Stinson, F.S.3    Grant, B.F.4
  • 54
    • 3543055314 scopus 로고    scopus 로고
    • Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: Results from the National Epidemiologic Survey on Alcohol and Related Conditions
    • Grant BF, Stinson FS, Dawson DA, Chou SP, Dufour MC, Compton W et al. Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry 2004; 61: 807-816.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 807-816
    • Grant, B.F.1    Stinson, F.S.2    Dawson, D.A.3    Chou, S.P.4    Dufour, M.C.5    Compton, W.6
  • 56
    • 57849090969 scopus 로고    scopus 로고
    • Effects of substance P in the amygdala, ventromedial hypothalamus, and periaqueductal gray on fear-potentiated startle
    • Zhao Z, Yang Y, Walker DL, Davis M. Effects of substance P in the amygdala, ventromedial hypothalamus, and periaqueductal gray on fear-potentiated startle. Neuropsychopharmacology 2008; 34: 331-340.
    • (2008) Neuropsychopharmacology , vol.34 , pp. 331-340
    • Zhao, Z.1    Yang, Y.2    Walker, D.L.3    Davis, M.4
  • 57
    • 84920569100 scopus 로고    scopus 로고
    • Alterations in HPA-axis and autonomic nervous system functioning in childhood anxiety disorders point to a chronic stress hypothesis
    • Dieleman GC, Huizink AC, Tulen JHM, Utens EMWJ, Creemers HE, van der Ende J et al. Alterations in HPA-axis and autonomic nervous system functioning in childhood anxiety disorders point to a chronic stress hypothesis. Psychoneuroendocrinology 2015; 51: 135-150.
    • (2015) Psychoneuroendocrinology , vol.51 , pp. 135-150
    • Dieleman, G.C.1    Huizink, A.C.2    Tulen, J.H.M.3    Utens, E.M.W.J.4    Creemers, H.E.5    Van Der Ende, J.6
  • 58
    • 22244443079 scopus 로고    scopus 로고
    • Corticotropin-releasing factor mRNA and substance P receptor binding in the paraventricular hypothalamic nucleus, central nucleus of the amygdala, and locus coeruleus of sprague-dawley rats following restraint-induced stress
    • Hwang BH, Katner J, Iyengar S. Corticotropin-releasing factor mRNA and substance P receptor binding in the paraventricular hypothalamic nucleus, central nucleus of the amygdala, and locus coeruleus of sprague-dawley rats following restraint-induced stress. J Mol Neurosci 2005; 25: 239-250.
    • (2005) J Mol Neurosci , vol.25 , pp. 239-250
    • Hwang, B.H.1    Katner, J.2    Iyengar, S.3
  • 59
    • 0035852719 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function
    • Santarelli L, Gobbi G, Debs PC, Sibille EL, Blier P, Hen R et al. Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function. Proc Natl Acad Sci USA 2001; 98: 1912-1917.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1912-1917
    • Santarelli, L.1    Gobbi, G.2    Debs, P.C.3    Sibille, E.L.4    Blier, P.5    Hen, R.6
  • 60
    • 84870157664 scopus 로고    scopus 로고
    • Neuroimaging of serotonin system in anxiety disorders
    • Maron E, Nutt D, Shlik J. Neuroimaging of serotonin system in anxiety disorders. Curr Pharm Des 2012; 18: 5699-5708.
    • (2012) Curr Pharm Des , vol.18 , pp. 5699-5708
    • Maron, E.1    Nutt, D.2    Shlik, J.3
  • 61
    • 22544472682 scopus 로고    scopus 로고
    • Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: Comparison with antidepressant drugs
    • Gobbi G, Blier P. Effect of neurokinin-1 receptor antagonists on serotoninergic, noradrenergic and hippocampal neurons: comparison with antidepressant drugs. Peptides 2005; 26: 1383-1393.
    • (2005) Peptides , vol.26 , pp. 1383-1393
    • Gobbi, G.1    Blier, P.2
  • 62
    • 0030580383 scopus 로고    scopus 로고
    • Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat
    • Shirayama Y, Mitsushio H, Takashima M, Ichikawa H, Takahashi K. Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat. Brain Res 1996; 739: 70-78.
    • (1996) Brain Res , vol.739 , pp. 70-78
    • Shirayama, Y.1    Mitsushio, H.2    Takashima, M.3    Ichikawa, H.4    Takahashi, K.5
  • 63
    • 53649104789 scopus 로고    scopus 로고
    • Oxytocin release from the rat neurohypophysis into the blood: Effects of tachykinin NK-1 and NK-2 receptors agonists and antagonists
    • Juszczak M, Boczek-Leszczyk E. Oxytocin release from the rat neurohypophysis into the blood: effects of tachykinin NK-1 and NK-2 receptors agonists and antagonists. J Physiol Pharmacol 2008; 59: 553-562.
    • (2008) J Physiol Pharmacol , vol.59 , pp. 553-562
    • Juszczak, M.1    Boczek-Leszczyk, E.2
  • 64
    • 84872856673 scopus 로고    scopus 로고
    • Corticolimbic brain reactivity to social signals of threat before and after sertraline treatment in generalized social phobia
    • Phan KL, Coccaro EF, Angstadt M, Kreger KJ, Mayberg HS, Liberzon I et al. Corticolimbic brain reactivity to social signals of threat before and after sertraline treatment in generalized social phobia. Biol Psychiatry 2013; 73: 329-336.
    • (2013) Biol Psychiatry , vol.73 , pp. 329-336
    • Phan, K.L.1    Coccaro, E.F.2    Angstadt, M.3    Kreger, K.J.4    Mayberg, H.S.5    Liberzon, I.6
  • 65
  • 66
    • 84875742716 scopus 로고    scopus 로고
    • Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats
    • Schank JR, Tapocik JD, Barbier E, Damadzic R, Eskay RL, Sun H et al. Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats. Biol Psychiatry 2013; 73: 774-781.
    • (2013) Biol Psychiatry , vol.73 , pp. 774-781
    • Schank, J.R.1    Tapocik, J.D.2    Barbier, E.3    Damadzic, R.4    Eskay, R.L.5    Sun, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.