Loss of the mono-ADP-ribosyltransferase, tiparp, increases sensitivity to dioxin-induced steatohepatitis and lethality

Journal of Biological Chemistry

Volumn 290, Issue 27, 2015, Pages 16824-16840

  Ahmed, Shaimaa ^a   Bott, Debbie ^a   Gomez, Alvin ^a   Tamblyn, Laura ^a   Rasheed, Adil ^a   Cho, Tiffany ^a   MacPherson, Laura ^a   Sugamori, Kim S ^a   Yang, Yang ^a   Grant, Denis M ^a   Cummins, Carolyn L ^a   Matthews, Jason ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

TOXICITY;

ADP-RIBOSYLATION; ADP-RIBOSYLTRANSFERASE; ARYL HYDROCARBON RECEPTOR;

ORGANIC POLLUTANTS;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN INDUCIBLE POLY(ADENOSINE DIPHOSPHATE RIBOSE)POLYMERASE; AROMATIC HYDROCARBON RECEPTOR; CXCL2 CHEMOKINE; GLYCOSYLTRANSFERASE; INTERLEUKIN 1BETA; MACROD1 PROTEIN; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; UNCLASSIFIED DRUG; 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN POLY(ADP-RIBOSE) POLYMERASE, MOUSE; AHR PROTEIN, MOUSE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DIOXIN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DRUG SENSITIVITY; FEMALE; GENE; GENE DELETION; GENE EXPRESSION; INTRACELLULAR SIGNALING; LETHALITY; LIVER TOXICITY; MALE; MOLECULAR PATHOLOGY; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SURVIVAL TIME; TIPARP GENE; WEIGHT REDUCTION; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; ENZYMOLOGY; FATTY LIVER; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MORTALITY;

MUS;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DIOXINS; FATTY LIVER; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLY(ADP-RIBOSE) POLYMERASES; RECEPTORS, ARYL HYDROCARBON;

EID: 84936816934     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.660100     Document Type: Article

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