Regulation of gene editing activity directed by single-stranded oligonucleotides and CRISPR/Cas9 systems

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Bialk, Pawel ^a,b   Rivera Torres, Natalia ^a   Strouse, Bryan ^a,c   Kmiec, Eric B ^a  

^a DELAWARE STATE UNIVERSITY   (United States)

^b HELEN F GRAHAM CANCER CENTER   (United States)

^c ProNAi Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRISPR ASSOCIATED PROTEIN; DOUBLE STRANDED DNA; PROTEIN CAS9; REGULATOR PROTEIN; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE I; GUIDE RNA; OLIGONUCLEOTIDE; PROTEIN BINDING;

ARTICLE; CELL SYNCHRONIZATION; CELL VIABILITY; COMPLEX FORMATION; DNA CLEAVAGE; DNA REPAIR; DNA STRAND BREAKAGE; GENE ACTIVITY; GENE CONTROL; GENE SEQUENCE; GENE TARGETING; GENETIC TRANSFECTION; PHENOTYPE; RNA SEQUENCE; BINDING SITE; CATALYSIS; CELL LINE; CRISPR CAS SYSTEM; GENE EXPRESSION; GENE VECTOR; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; REPORTER GENE; RNA EDITING;

BASE SEQUENCE; BINDING SITES; CATALYSIS; CELL LINE; CRISPR-CAS SYSTEMS; DEOXYRIBONUCLEASE I; DNA, SINGLE-STRANDED; GENE EXPRESSION; GENE TARGETING; GENES, REPORTER; GENETIC VECTORS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDES; PROTEIN BINDING; RNA EDITING; RNA, GUIDE; TRANSFECTION;

EID: 84936806634     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0129308     Document Type: Article

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