The position of DNA cleavage by TALENs and cell synchronization influences the frequency of gene editing directed by single-stranded oligonucleotides

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Rivera Torres, Natalia ^a   Strouse, Bryan ^a   Bialk, Pawel ^a   Niamat, Rohina A ^a   Kmiec, Eric B ^a  

^a DELAWARE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENDONUCLEASE; ENHANCED GREEN FLUORESCENT PROTEIN; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE; OLIGONUCLEOTIDE; SINGLE STRANDED DNA;

ARTICLE; CELL SYNCHRONIZATION; CONTROLLED STUDY; DNA CLEAVAGE; EGFP GENE; ENZYME ACTIVITY; GENE; GENE EDITING; GENE FREQUENCY; GENOMICS; HUMAN; HUMAN CELL; MISSENSE MUTATION; NONHUMAN; SINGLE STRANDED DNA BREAK; SITE DIRECTED MUTAGENESIS; CHEMISTRY; CULTURE TECHNIQUE; GENE TARGETING; HCT116 CELL LINE; METABOLISM; PROCEDURES;

CELL CULTURE TECHNIQUES; DEOXYRIBONUCLEASES; DNA CLEAVAGE; DNA, SINGLE-STRANDED; GENE TARGETING; HCT116 CELLS; HUMANS; OLIGONUCLEOTIDES;

EID: 84900330263     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096483     Document Type: Article

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