Bilirubin inhibits the up-regulation of inducible nitric oxide synthase by scavenging reactive oxygen species generated by the toll-like receptor 4-dependent activation of NADPH oxidase

Redox Biology

Volumn 5, Issue , 2015, Pages 398-408

  Idelman, Gila ^a   Smith, Darcey L H ^a   Zucker, Stephen D ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

Aryl hydrocarbon receptor (AhR); Bilirubin; Hypoxia inducible factor (HIF); NADPH oxidase; Nitric oxide synthase; Superoxide; Toll like receptor 4 (TLR4)

Indexed keywords

MURINAE;

AROMATIC HYDROCARBON RECEPTOR; BILIRUBIN; CYTOKINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC ACID DERIVATIVE; POLYCHLORINATED DIBENZODIOXIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TOLL LIKE RECEPTOR 4;

AGONISTS; ANIMAL; CELL LINE; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; MOUSE; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; BILIRUBIN; CELL LINE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIPOPOLYSACCHARIDES; MICE; NADPH OXIDASE; NITRATES; NITRIC OXIDE SYNTHASE TYPE II; POLYCHLORINATED DIBENZODIOXINS; REACTIVE OXYGEN SPECIES; RECEPTORS, ARYL HYDROCARBON; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 84936768984     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2015.06.008     Document Type: Article

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