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Volumn 36, Issue 4, 2015, Pages 3093-3100

Upregulated expression of miR-106a by DNA hypomethylation plays an oncogenic role in hepatocellular carcinoma

Author keywords

Hepatocellular carcinoma; Hypomethylation; miR 106a; Oncogene

Indexed keywords

MICRORNA; MIRN106 MICRORNA, HUMAN; TUMOR MARKER;

EID: 84936765265     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-2945-2     Document Type: Article
Times cited : (33)

References (38)
  • 2
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • COI: 1:CAS:528:DC%2BC3cXhtlWhs7fO, PID: 21351269
    • Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127(12):2893–917. doi:10.1002/ijc.25516.
    • (2010) Int J Cancer , vol.127 , Issue.12 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3    Forman, D.4    Mathers, C.5    Parkin, D.M.6
  • 4
    • 80053088189 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC3MXht1WqtrnL, PID: 21992124
    • El-Serag HB. Hepatocellular carcinoma. N Engl J Med. 2011;365(12):1118–27. doi:10.1056/NEJMra1001683.
    • (2011) N Engl J Med , vol.365 , Issue.12 , pp. 1118-1127
    • El-Serag, H.B.1
  • 5
    • 80052348326 scopus 로고    scopus 로고
    • Surveillance for hepatocellular carcinoma: in whom and how?
    • El-Serag HB, Davila JA. Surveillance for hepatocellular carcinoma: in whom and how? Ther Adv Gastroenterol. 2011;4(1):5–10. doi:10.1177/1756283X10385964.
    • (2011) Ther Adv Gastroenterol , vol.4 , Issue.1 , pp. 5-10
    • El-Serag, H.B.1    Davila, J.A.2
  • 6
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • PID: 22353262
    • Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet. 2012;379(9822):1245–55. doi:10.1016/S0140-6736(11)61347-0.
    • (2012) Lancet , vol.379 , Issue.9822 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 7
    • 79955631558 scopus 로고    scopus 로고
    • Genetics of hepatobiliary carcinogenesis
    • COI: 1:CAS:528:DC%2BC3MXotFWntrk%3D, PID: 21538283
    • Nault JC, Zucman-Rossi J. Genetics of hepatobiliary carcinogenesis. Semin Liver Dis. 2011;31(2):173–87. doi:10.1055/s-0031-1276646.
    • (2011) Semin Liver Dis , vol.31 , Issue.2 , pp. 173-187
    • Nault, J.C.1    Zucman-Rossi, J.2
  • 8
    • 79955599940 scopus 로고    scopus 로고
    • Genetic and epigenetic signatures in human hepatocellular carcinoma: a systematic review
    • COI: 1:CAS:528:DC%2BC3MXnt1CjsLk%3D, PID: 21966251
    • Nishida N, Goel A. Genetic and epigenetic signatures in human hepatocellular carcinoma: a systematic review. Curr Genomics. 2011;12(2):130–7. doi:10.2174/138920211795564359.
    • (2011) Curr Genomics , vol.12 , Issue.2 , pp. 130-137
    • Nishida, N.1    Goel, A.2
  • 9
    • 84872527492 scopus 로고    scopus 로고
    • Genome-wide epigenetic regulation of miRNAs in cancer
    • COI: 1:CAS:528:DC%2BC3sXptlamtw%3D%3D, PID: 23316035
    • Baer C, Claus R, Plass C. Genome-wide epigenetic regulation of miRNAs in cancer. Cancer Res. 2013;73(2):473–7. doi:10.1158/0008-5472.CAN-12-3731.
    • (2013) Cancer Res , vol.73 , Issue.2 , pp. 473-477
    • Baer, C.1    Claus, R.2    Plass, C.3
  • 10
    • 79551712007 scopus 로고    scopus 로고
    • The role of epigenetic transcription repression and DNA methyltransferases in cancer
    • COI: 1:CAS:528:DC%2BC3MXislegu7o%3D, PID: 20945317
    • Daniel FI, Cherubini K, Yurgel LS, de Figueiredo MA, Salum FG. The role of epigenetic transcription repression and DNA methyltransferases in cancer. Cancer. 2011;117(4):677–87. doi:10.1002/cncr.25482.
    • (2011) Cancer , vol.117 , Issue.4 , pp. 677-687
    • Daniel, F.I.1    Cherubini, K.2    Yurgel, L.S.3    de Figueiredo, M.A.4    Salum, F.G.5
  • 11
    • 77957355926 scopus 로고    scopus 로고
    • Epigenetics and miRNAs in human cancer
    • COI: 1:CAS:528:DC%2BC3cXhs1SisrfL, PID: 20920746
    • Fabbri M, Calin GA. Epigenetics and miRNAs in human cancer. Adv Genet. 2010;70:87–99. doi:10.1016/B978-0-12-380866-0.60004-6.
    • (2010) Adv Genet , vol.70 , pp. 87-99
    • Fabbri, M.1    Calin, G.A.2
  • 12
    • 79955581917 scopus 로고    scopus 로고
    • MicroRNAs and epigenetics
    • COI: 1:CAS:528:DC%2BC3MXmsVKktbk%3D, PID: 21395977
    • Sato F, Tsuchiya S, Meltzer SJ, Shimizu K. MicroRNAs and epigenetics. FEBS J. 2011;278(10):1598–609. doi:10.1111/j.1742-4658.2011.08089.x.
    • (2011) FEBS J , vol.278 , Issue.10 , pp. 1598-1609
    • Sato, F.1    Tsuchiya, S.2    Meltzer, S.J.3    Shimizu, K.4
  • 13
    • 84883514750 scopus 로고    scopus 로고
    • Epigenetics of hepatocellular carcinoma: role of microRNA
    • PID: 24023486
    • Khare S, Zhang Q, Ibdah JA. Epigenetics of hepatocellular carcinoma: role of microRNA. World J Gastroenterol. 2013;19(33):5439–45. doi:10.3748/wjg.v19.i33.5439.
    • (2013) World J Gastroenterol , vol.19 , Issue.33 , pp. 5439-5445
    • Khare, S.1    Zhang, Q.2    Ibdah, J.A.3
  • 14
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • COI: 1:CAS:528:DC%2BD2cXhtVals7o%3D, PID: 14744438
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116(2):281–97.
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 15
    • 33847727035 scopus 로고    scopus 로고
    • Jackson RJ, Standart N. How do microRNAs regulate gene expression? Sci STKE. 2007;2007(367):re1
    • Jackson RJ, Standart N. How do microRNAs regulate gene expression? Sci STKE. 2007;2007(367):re1. doi:10.1126/stke.3672007re1.
  • 16
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • COI: 1:CAS:528:DC%2BD2sXntlOnuw%3D%3D, PID: 16989803
    • Zhang B, Pan X, Cobb GP, Anderson TA. MicroRNAs as oncogenes and tumor suppressors. Dev Biol. 2007;302(1):1–12. doi:10.1016/j.ydbio.2006.08.028.
    • (2007) Dev Biol , vol.302 , Issue.1 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 17
    • 77957366305 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • PID: 20920744
    • Kulis M, Esteller M. DNA methylation and cancer. Adv Genet. 2010;70:27–56. doi:10.1016/B978-0-12-380866-0.60002-2.
    • (2010) Adv Genet , vol.70 , pp. 27-56
    • Kulis, M.1    Esteller, M.2
  • 18
    • 84873701727 scopus 로고    scopus 로고
    • Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in HCC
    • COI: 1:CAS:528:DC%2BC3sXltV2qs74%3D, PID: 23402613
    • Chen X, Zhang L, Zhang T, Hao M, Zhang X, Zhang J, et al. Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in HCC. Liver Int. 2013;33(3):476–86. doi:10.1111/liv.12097.
    • (2013) Liver Int , vol.33 , Issue.3 , pp. 476-486
    • Chen, X.1    Zhang, L.2    Zhang, T.3    Hao, M.4    Zhang, X.5    Zhang, J.6
  • 19
    • 84873686697 scopus 로고    scopus 로고
    • Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC3sXisV2kurg%3D, PID: 23229728
    • Dohi O, Yasui K, Gen Y, Takada H, Endo M, Tsuji K, et al. Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma. Int J Oncol. 2013;42(2):411–8. doi:10.3892/ijo.2012.1724.
    • (2013) Int J Oncol , vol.42 , Issue.2 , pp. 411-418
    • Dohi, O.1    Yasui, K.2    Gen, Y.3    Takada, H.4    Endo, M.5    Tsuji, K.6
  • 20
    • 84899522812 scopus 로고    scopus 로고
    • MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in hepatocellular carcinogenesis
    • COI: 1:CAS:528:DC%2BC2cXhtlait73L, PID: 24714841
    • Long XR, He Y, Huang C, Li J. MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in hepatocellular carcinogenesis. Int J Oncol. 2014;44(6):1915–22. doi:10.3892/ijo.2014.2373.
    • (2014) Int J Oncol , vol.44 , Issue.6 , pp. 1915-1922
    • Long, X.R.1    He, Y.2    Huang, C.3    Li, J.4
  • 21
    • 84899646114 scopus 로고    scopus 로고
    • Methylation-associated silencing of microRNA-34b in hepatocellular carcinoma cancer
    • COI: 1:CAS:528:DC%2BC2cXmtVSit7o%3D, PID: 24704024
    • Xie K, Liu J, Chen J, Dong J, Ma H, Liu Y, et al. Methylation-associated silencing of microRNA-34b in hepatocellular carcinoma cancer. Gene. 2014;543(1):101–7. doi:10.1016/j.gene.2014.03.059.
    • (2014) Gene , vol.543 , Issue.1 , pp. 101-107
    • Xie, K.1    Liu, J.2    Chen, J.3    Dong, J.4    Ma, H.5    Liu, Y.6
  • 22
    • 84906871291 scopus 로고    scopus 로고
    • DNA methylation-mediated repression of miR-941 enhances lysine (K)-specific demethylase 6B expression in hepatoma cells
    • COI: 1:CAS:528:DC%2BC2cXhsVGjtL7N, PID: 25049231
    • Zhang PP, Wang XL, Zhao W, Qi B, Yang Q, Wan HY, et al. DNA methylation-mediated repression of miR-941 enhances lysine (K)-specific demethylase 6B expression in hepatoma cells. J Biol Chem. 2014;289(35):24724–35. doi:10.1074/jbc.M114.567818.
    • (2014) J Biol Chem , vol.289 , Issue.35 , pp. 24724-24735
    • Zhang, P.P.1    Wang, X.L.2    Zhao, W.3    Qi, B.4    Yang, Q.5    Wan, H.Y.6
  • 23
    • 77955517749 scopus 로고    scopus 로고
    • hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations
    • COI: 1:CAS:528:DC%2BC3cXhtVSmtb%2FF, PID: 20628378
    • Wang F, Xue X, Wei J, An Y, Yao J, Cai H, et al. hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion, and side populations. Br J Cancer. 2010;103(4):567–74. doi:10.1038/sj.bjc.6605724.
    • (2010) Br J Cancer , vol.103 , Issue.4 , pp. 567-574
    • Wang, F.1    Xue, X.2    Wei, J.3    An, Y.4    Yao, J.5    Cai, H.6
  • 24
    • 84896535861 scopus 로고    scopus 로고
    • Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes
    • COI: 1:CAS:528:DC%2BC2cXktF2rtr8%3D, PID: 24390737
    • Ma L, Liu J, Liu L, Duan G, Wang Q, Xu Y, et al. Overexpression of the transcription factor MEF2D in hepatocellular carcinoma sustains malignant character by suppressing G2-M transition genes. Cancer Res. 2014;74(5):1452–62. doi:10.1158/0008-5472.CAN-13-2171.
    • (2014) Cancer Res , vol.74 , Issue.5 , pp. 1452-1462
    • Ma, L.1    Liu, J.2    Liu, L.3    Duan, G.4    Wang, Q.5    Xu, Y.6
  • 25
    • 84896716202 scopus 로고    scopus 로고
    • MicroRNA-106a targets TIMP2 to regulate invasion and metastasis of gastric cancer
    • COI: 1:CAS:528:DC%2BC2cXhsVykt70%3D, PID: 24440352
    • Zhu M, Zhang N, He S, Lui Y, Lu G, Zhao L. MicroRNA-106a targets TIMP2 to regulate invasion and metastasis of gastric cancer. FEBS Lett. 2014;588(4):600–7. doi:10.1016/j.febslet.2013.12.028.
    • (2014) FEBS Lett , vol.588 , Issue.4 , pp. 600-607
    • Zhu, M.1    Zhang, N.2    He, S.3    Lui, Y.4    Lu, G.5    Zhao, L.6
  • 26
    • 84896730351 scopus 로고    scopus 로고
    • Upregulated miR-106a plays an oncogenic role in pancreatic cancer
    • COI: 1:CAS:528:DC%2BC2cXhs1Grsbc%3D, PID: 24444603
    • Li P, Xu Q, Zhang D, Li X, Han L, Lei J, et al. Upregulated miR-106a plays an oncogenic role in pancreatic cancer. FEBS Lett. 2014;588(5):705–12. doi:10.1016/j.febslet.2014.01.007.
    • (2014) FEBS Lett , vol.588 , Issue.5 , pp. 705-712
    • Li, P.1    Xu, Q.2    Zhang, D.3    Li, X.4    Han, L.5    Lei, J.6
  • 27
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • COI: 1:CAS:528:DyaK2cXhtVShsLk%3D, PID: 8242751
    • Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 1993;75(4):805–16.
    • (1993) Cell , vol.75 , Issue.4 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 28
    • 84876859512 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p20 controls circadian cell-cycle timing
    • COI: 1:CAS:528:DC%2BC3sXot1Ghsbc%3D, PID: 23569261
    • Laranjeiro R, Tamai TK, Peyric E, Krusche P, Ott S, Whitmore D. Cyclin-dependent kinase inhibitor p20 controls circadian cell-cycle timing. Proc Natl Acad Sci U S A. 2013;110(17):6835–40. doi:10.1073/pnas.1217912110.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.17 , pp. 6835-6840
    • Laranjeiro, R.1    Tamai, T.K.2    Peyric, E.3    Krusche, P.4    Ott, S.5    Whitmore, D.6
  • 29
    • 77349103260 scopus 로고    scopus 로고
    • Pathology of early hepatocellular carcinoma: conventional and molecular diagnosis
    • PID: 20175030
    • Roskams T, Kojiro M. Pathology of early hepatocellular carcinoma: conventional and molecular diagnosis. Semin Liver Dis. 2010;30(1):17–25. doi:10.1055/s-0030-1247129.
    • (2010) Semin Liver Dis , vol.30 , Issue.1 , pp. 17-25
    • Roskams, T.1    Kojiro, M.2
  • 30
    • 84873726893 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of hepatocellular carcinoma: an update
    • COI: 1:CAS:528:DC%2BC38Xhtl2gu7zI, PID: 23007558
    • Aravalli RN, Cressman EN, Steer CJ. Cellular and molecular mechanisms of hepatocellular carcinoma: an update. Arch Toxicol. 2013;87(2):227–47. doi:10.1007/s00204-012-0931-2.
    • (2013) Arch Toxicol , vol.87 , Issue.2 , pp. 227-247
    • Aravalli, R.N.1    Cressman, E.N.2    Steer, C.J.3
  • 31
    • 84916631830 scopus 로고    scopus 로고
    • Hepatocellular carcinoma tumour markers: current role and expectations
    • COI: 1:CAS:528:DC%2BC2cXhsFSiur7J, PID: 25260312
    • Rich N, Singal AG. Hepatocellular carcinoma tumour markers: current role and expectations. Best Pract Res Clin Gastroenterol. 2014;28(5):843–53. doi:10.1016/j.bpg.2014.07.018.
    • (2014) Best Pract Res Clin Gastroenterol , vol.28 , Issue.5 , pp. 843-853
    • Rich, N.1    Singal, A.G.2
  • 32
    • 84903199903 scopus 로고    scopus 로고
    • DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma
    • PID: 24976726
    • Anwar SL, Lehmann U. DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma. World J Gastroenterol. 2014;20(24):7894–913. doi:10.3748/wjg.v20.i24.7894.
    • (2014) World J Gastroenterol , vol.20 , Issue.24 , pp. 7894-7913
    • Anwar, S.L.1    Lehmann, U.2
  • 33
    • 84880325375 scopus 로고    scopus 로고
    • miR-106a is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS
    • COI: 1:CAS:528:DC%2BC38XjvVWltb8%3D, PID: 22431000
    • Wang Z, Liu M, Zhu H, Zhang W, He S, Hu C, et al. miR-106a is frequently upregulated in gastric cancer and inhibits the extrinsic apoptotic pathway by targeting FAS. Mol Carcinog. 2013;52(8):634–46. doi:10.1002/mc.21899.
    • (2013) Mol Carcinog , vol.52 , Issue.8 , pp. 634-646
    • Wang, Z.1    Liu, M.2    Zhu, H.3    Zhang, W.4    He, S.5    Hu, C.6
  • 34
    • 84870868566 scopus 로고    scopus 로고
    • miR-106a overexpression and pRB downregulation in sporadic colorectal cancer
    • COI: 1:CAS:528:DC%2BC3sXhs1Ciu70%3D, PID: 23178825
    • Catela Ivkovic T, Aralica G, Cacev T, Loncar B, Kapitanovic S. miR-106a overexpression and pRB downregulation in sporadic colorectal cancer. Exp Mol Pathol. 2013;94(1):148–54. doi:10.1016/j.yexmp.2012.11.002.
    • (2013) Exp Mol Pathol , vol.94 , Issue.1 , pp. 148-154
    • Catela Ivkovic, T.1    Aralica, G.2    Cacev, T.3    Loncar, B.4    Kapitanovic, S.5
  • 35
    • 84881098636 scopus 로고    scopus 로고
    • Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer
    • COI: 1:CAS:528:DC%2BC3sXhtFOit7jP, PID: 23807165
    • Huh JH, Kim TH, Kim K, Song JA, Jung YJ, Jeong JY, et al. Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer. Br J Cancer. 2013;109(2):452–61. doi:10.1038/bjc.2013.305.
    • (2013) Br J Cancer , vol.109 , Issue.2 , pp. 452-461
    • Huh, J.H.1    Kim, T.H.2    Kim, K.3    Song, J.A.4    Jung, Y.J.5    Jeong, J.Y.6
  • 36
    • 84885351203 scopus 로고    scopus 로고
    • Decreased miR-106a inhibits glioma cell glucose uptake and proliferation by targeting SLC2A3 in GBM
    • PID: 24124917
    • Dai DW, Lu Q, Wang LX, Zhao WY, Cao YQ, Li YN, et al. Decreased miR-106a inhibits glioma cell glucose uptake and proliferation by targeting SLC2A3 in GBM. BMC Cancer. 2013;13:478. doi:10.1186/1471-2407-13-478.
    • (2013) BMC Cancer , vol.13 , pp. 478
    • Dai, D.W.1    Lu, Q.2    Wang, L.X.3    Zhao, W.Y.4    Cao, Y.Q.5    Li, Y.N.6
  • 37
    • 83255162659 scopus 로고    scopus 로고
    • An HNF4alpha-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis
    • COI: 1:CAS:528:DC%2BC3MXhs1SgtrzP, PID: 22153071
    • Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, et al. An HNF4alpha-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell. 2011;147(6):1233–47. doi:10.1016/j.cell.2011.10.043.
    • (2011) Cell , vol.147 , Issue.6 , pp. 1233-1247
    • Hatziapostolou, M.1    Polytarchou, C.2    Aggelidou, E.3    Drakaki, A.4    Poultsides, G.A.5    Jaeger, S.A.6
  • 38
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • COI: 1:CAS:528:DC%2BD1MXps1eiurg%3D, PID: 19524505
    • Kota J, Chivukula RR, O’Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell. 2009;137(6):1005–17. doi:10.1016/j.cell.2009.04.021.
    • (2009) Cell , vol.137 , Issue.6 , pp. 1005-1017
    • Kota, J.1    Chivukula, R.R.2    O’Donnell, K.A.3    Wentzel, E.A.4    Montgomery, C.L.5    Hwang, H.W.6


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