A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure

Human Genetics

Volumn 134, Issue 6, 2015, Pages 627-636

  Turpeinen, Hannu ^a   Seppälä, Ilkka ^a   Lyytikäinen, Leo Pekka ^a   Raitoharju, Emma ^a   Hutri Kähönen, Nina ^a   Levula, Mari ^a   Oksala, Niku ^b   Waldenberger, Melanie ^c   Klopp, Norman ^c,d   Illig, Thomas ^c,d   Mononen, Nina ^a   Laaksonen, Reijo ^a   Raitakari, Olli ^e,f   Kähönen, Mika ^a   Lehtimäki, Terho ^a   Pesu, Marko ^a,b,g  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e TURKU UNIVERSITY HOSPITAL   (Finland)

^f UNIVERSITY OF TURKU   (Finland)

^g PIRKANMAA HOSPITAL DISTRICT   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

FURIN; FURIN PROTEIN, HUMAN; MEMBRANE-BOUND TRANSCRIPTION FACTOR PEPTIDASE, SITE 1; PCSK7 PROTEIN, HUMAN; SERINE PROTEINASE; SUBTILISIN;

BIOSYNTHESIS; BLOOD PRESSURE; CLINICAL TRIAL; FEMALE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETICS; HUMAN; MALE; MULTICENTER STUDY; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; VASCULAR RESISTANCE;

BLOOD PRESSURE; FEMALE; FURIN; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPROTEIN CONVERTASES; QUANTITATIVE TRAIT LOCI; SERINE ENDOPEPTIDASES; SUBTILISINS; VASCULAR RESISTANCE;

EID: 84936752765     PISSN: 03406717     EISSN: 14321203     Source Type: Journal    
DOI: 10.1007/s00439-015-1546-5     Document Type: Article

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