Proprotein Convertase Subtilisin/Kexin Type 3 Promotes Adipose Tissue-Driven Macrophage Chemotaxis and Is Increased in Obesity

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Kappert, Kai ^a,b   Meyborg, Heike ^a   Fritzsche, Jan ^a   Urban, Daniel ^a   Krüger, Janine ^b   Wellnhofer, Ernst ^a   Kintscher, Ulrich ^b   Fleck, Eckart ^a   Stawowy, Philipp ^a  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FURIN; GELATINASE B; MATRIX METALLOPROTEINASE; MEMBRANE TETHERED 1 MATRIX METALLOPROTEINASE; PROTEIN SERPINB8; RESISTIN; SERINE PROTEINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY MASS; CELL DIFFERENTIATION; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CHEMOTAXIS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; MACROPHAGE; MACROPHAGE MIGRATION; MALE; MONOCYTE; MONONUCLEAR CELL; MOUSE; NONHUMAN; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; UPREGULATION; WHITE ADIPOSE TISSUE;

ADIPOSE TISSUE; ANIMALS; CELL LINE; CHEMOTAXIS; ENZYME ACTIVATION; ENZYME PRECURSORS; FEMALE; FURIN; HUMANS; HYPERTENSION; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 14; MICE; MIDDLE AGED; MONOCYTES; OBESITY; RESISTIN; SERPINS;

EID: 84881226961     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070542     Document Type: Article

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