Diabetes primes neutrophils to undergo NETosis, which impairs wound healing

Nature Medicine

Volumn 21, Issue 7, 2015, Pages 815-819

  Wong, Siu Ling ^a,b   Demers, Melanie ^a,b   Martinod, Kimberly ^a,b   Gallant, Maureen ^a   Wang, Yanming ^c   Goldfine, Allison B ^b   Kahn, C Ronald ^b   Wagner, Denisa D ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE I; GLUCOSE; HISTONE H3; PROTEIN ARGININE DEIMINASE; PROTEIN ARGININE DEIMINASE 4; UNCLASSIFIED DRUG; GLUCOSE BLOOD LEVEL; HISTONE; HYDROLASE; IONOMYCIN; PEPTIDYLARGININE DEIMINASE 4, MOUSE;

ANIMAL CELL; ARTICLE; CELL DISRUPTION; CELL ISOLATION; CHROMATIN CONDENSATION; CONTROLLED STUDY; DIABETES MELLITUS; EXCISION; EXTRACELLULAR TRAP; FEMALE; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOUSE; NEUTROPHIL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INJURY; WILD TYPE; WOUND HEALING; WOUND HEALING IMPAIRMENT; ADULT; ANIMAL; C57BL MOUSE; DEFICIENCY; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; METABOLISM; MIDDLE AGED; PATHOLOGY; TIME; WESTERN BLOTTING; YOUNG ADULT;

MUS;

ADULT; ANIMALS; BLOOD GLUCOSE; BLOTTING, WESTERN; DEOXYRIBONUCLEASE I; DIABETES MELLITUS, EXPERIMENTAL; EXTRACELLULAR TRAPS; FEMALE; HISTONES; HUMANS; HYDROLASES; IONOMYCIN; MALE; MICE, INBRED C57BL; MIDDLE AGED; NEUTROPHILS; TIME FACTORS; WOUND HEALING; YOUNG ADULT;

EID: 84936752526     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3887     Document Type: Article

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