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Volumn 31, Issue 12, 2014, Pages 3404-3414

Oral delivery of Glucagon like peptide-1 by a recombinant Lactococcus lactis

Author keywords

GLP 1; L. lactis; normal flora; oral protein delivery; type 2 diabetes

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCOSE BLOOD LEVEL; INSULIN;

EID: 84936102267     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1430-3     Document Type: Article
Times cited : (52)

References (47)
  • 1
    • 0033188410 scopus 로고    scopus 로고
    • Control of glucose homeostasis by incretin hormones
    • 1:CAS:528:DyaK1MXns1alt7w%3D 11475276
    • Perfetti R, Brown TA, Velikina R, Busselen S. Control of glucose homeostasis by incretin hormones. Diabetes Technol Ther. 1999;1(3):297-305.
    • (1999) Diabetes Technol Ther , vol.1 , Issue.3 , pp. 297-305
    • Perfetti, R.1    Brown, T.A.2    Velikina, R.3    Busselen, S.4
  • 2
    • 58149090676 scopus 로고    scopus 로고
    • The role of incretins in glucose homeostasis and diabetes treatment
    • 1:CAS:528:DC%2BD1MXhsFGls7o%3D 2696340 19074620
    • Kim W, Egan JM. The role of incretins in glucose homeostasis and diabetes treatment. Pharmacol Rev. 2008;60(4):470-512.
    • (2008) Pharmacol Rev , vol.60 , Issue.4 , pp. 470-512
    • Kim, W.1    Egan, J.M.2
  • 3
    • 27244447025 scopus 로고    scopus 로고
    • On the role of the incretin hormones GIP and GLP-1 in the pathogenesis of Type 2 diabetes mellitus
    • 1:CAS:528:DC%2BD2MXmtVWisw%3D%3D 16009062
    • Vilsboll T. On the role of the incretin hormones GIP and GLP-1 in the pathogenesis of Type 2 diabetes mellitus. Dan Med Bull. 2004;51(4):364-70.
    • (2004) Dan Med Bull , vol.51 , Issue.4 , pp. 364-370
    • Vilsboll, T.1
  • 4
    • 0027227370 scopus 로고
    • Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: Acute post-prandial and 24-h secretion patterns
    • 1:CAS:528:DyaK3sXmt1Gjs7w%3D 7852887
    • Elliott RM, Morgan LM, Tredger JA, Deacon S, Wright J, Marks V. Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns. J Endocrinol. 1993;138(1):159-66.
    • (1993) J Endocrinol , vol.138 , Issue.1 , pp. 159-166
    • Elliott, R.M.1    Morgan, L.M.2    Tredger, J.A.3    Deacon, S.4    Wright, J.5    Marks, V.6
  • 5
    • 0037312821 scopus 로고    scopus 로고
    • The influence of GLP-1 on glucose-stimulated insulin secretion: Effects on beta-cell sensitivity in type 2 and nondiabetic subjects
    • 1:CAS:528:DC%2BD3sXhtFans7w%3D 12540611
    • Kjems LL, Holst JJ, Volund A, Madsbad S. The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects. Diabetes. 2003;52(2):380-6.
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 380-386
    • Kjems, L.L.1    Holst, J.J.2    Volund, A.3    Madsbad, S.4
  • 6
    • 0041733259 scopus 로고    scopus 로고
    • The glucagon-like peptides: A double-edged therapeutic sword?
    • 1:CAS:528:DC%2BD3sXltl2gtLw%3D 12871671
    • Perry T, Greig NH. The glucagon-like peptides: a double-edged therapeutic sword? Trends Pharmacol Sci. 2003;24(7):377-83.
    • (2003) Trends Pharmacol Sci , vol.24 , Issue.7 , pp. 377-383
    • Perry, T.1    Greig, N.H.2
  • 7
    • 17844362518 scopus 로고    scopus 로고
    • Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes
    • 1:CAS:528:DC%2BD2MXjtlGhsL0%3D 15770466
    • Mest HJ, Mentlein R. Dipeptidyl peptidase inhibitors as new drugs for the treatment of type 2 diabetes. Diabetologia. 2005;48(4):616-20.
    • (2005) Diabetologia , vol.48 , Issue.4 , pp. 616-620
    • Mest, H.J.1    Mentlein, R.2
  • 8
    • 0033619675 scopus 로고    scopus 로고
    • Dipeptidyl-peptidase IV, (CD26)-role in the inactivation of regulatory peptides
    • 1:CAS:528:DyaK1MXntVCitLs%3D 10588446
    • Mentlein R. Dipeptidyl-peptidase IV, (CD26)-role in the inactivation of regulatory peptides. Regul Pept. 1999;85(1):9-24.
    • (1999) Regul Pept , vol.85 , Issue.1 , pp. 9-24
    • Mentlein, R.1
  • 9
    • 79959559653 scopus 로고    scopus 로고
    • Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
    • 1:CAS:528:DC%2BC3MXosVGnsrY%3D 21334333
    • Elashoff M, Matveyenko AV, Gier B, Elashoff R, Butler PC. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology. 2011;141(1):150-6.
    • (2011) Gastroenterology , vol.141 , Issue.1 , pp. 150-156
    • Elashoff, M.1    Matveyenko, A.V.2    Gier, B.3    Elashoff, R.4    Butler, P.C.5
  • 10
    • 84876063836 scopus 로고    scopus 로고
    • Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: A population-based matched case-control study
    • 1:CAS:528:DC%2BC3sXmt1ektr0%3D 23440284
    • Singh S, Chang HY, Richards TM, Weiner JP, Clark JM, Segal JB. Glucagonlike peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study. JAMA Intern Med. 2013;173(7):534-9.
    • (2013) JAMA Intern Med , vol.173 , Issue.7 , pp. 534-539
    • Singh, S.1    Chang, H.Y.2    Richards, T.M.3    Weiner, J.P.4    Clark, J.M.5    Segal, J.B.6
  • 11
    • 84939902678 scopus 로고    scopus 로고
    • [01/10/2014]
    • [01/10/2014]; Available from: http://www.fda.gov/Drugs/DrugSafety/ucm343187.htm.
  • 12
    • 38349058997 scopus 로고    scopus 로고
    • Exenatide (Byetta) as a novel treatment option for type 2 diabetes mellitus
    • Bond A. Exenatide (Byetta) as a novel treatment option for type 2 diabetes mellitus. Proc (Bayl Univ Med Cent). 2006;19(3):281-4.
    • (2006) Proc (Bayl Univ Med Cent) , vol.19 , Issue.3 , pp. 281-284
    • Bond, A.1
  • 13
    • 0014149135 scopus 로고
    • Studies on the passage of alpha-chymotrypsin across the intestine
    • 1:CAS:528:DyaF1cXns1egtg%3D%3D
    • Moriya H, Moriwaki C, Akimoto S, Yamaguchi K, Iwadare M. Studies on the passage of alpha-chymotrypsin across the intestine. Chem Pharm Bull (Tokyo). 1967;15(11):1662-8.
    • (1967) Chem Pharm Bull (Tokyo) , vol.15 , Issue.11 , pp. 1662-1668
    • Moriya, H.1    Moriwaki, C.2    Akimoto, S.3    Yamaguchi, K.4    Iwadare, M.5
  • 14
    • 6944243070 scopus 로고    scopus 로고
    • Normal flora: Living vehicles for non-invasive protein drug delivery
    • 1:CAS:528:DC%2BD2cXovVSktrw%3D 15501008
    • Shao J, Kaushal G. Normal flora: living vehicles for non-invasive protein drug delivery. Int J Pharm. 2004;286(1-2):117-24.
    • (2004) Int J Pharm , vol.286 , Issue.1-2 , pp. 117-124
    • Shao, J.1    Kaushal, G.2
  • 15
  • 16
    • 0034714256 scopus 로고    scopus 로고
    • Immunology. Therapeutic manipulation of gut flora
    • 1:CAS:528:DC%2BD3cXmt1Wlsbs%3D 10979858
    • Shanahan F. Immunology. Therapeutic manipulation of gut flora. Science. 2000;289(5483):1311-2.
    • (2000) Science , vol.289 , Issue.5483 , pp. 1311-1312
    • Shanahan, F.1
  • 18
    • 33645277792 scopus 로고    scopus 로고
    • Delivery of TEM beta-lactamase by gene-transformed Lactococcus lactis subsp. Lactis through cervical cell monolayer
    • 1:CAS:528:DC%2BD28XjtVGqur0%3D 16488095
    • Kaushal G, Trombetta L, Ochs RS, Shao J. Delivery of TEM beta-lactamase by gene-transformed Lactococcus lactis subsp. lactis through cervical cell monolayer. Int J Pharm. 2006;313(1-2):29-35.
    • (2006) Int J Pharm , vol.313 , Issue.1-2 , pp. 29-35
    • Kaushal, G.1    Trombetta, L.2    Ochs, R.S.3    Shao, J.4
  • 19
    • 0030956641 scopus 로고    scopus 로고
    • Cell wall anchoring of the Streptococcus pyogenes M6 protein in various lactic acid bacteria
    • 1:CAS:528:DyaK2sXjtVCrtL8%3D 179078 9139932
    • Piard JC, Hautefort I, Fischetti VA, Ehrlich SD, Fons M, Gruss A. Cell wall anchoring of the Streptococcus pyogenes M6 protein in various lactic acid bacteria. J Bacteriol. 1997;179(9):3068-72.
    • (1997) J Bacteriol , vol.179 , Issue.9 , pp. 3068-3072
    • Piard, J.C.1    Hautefort, I.2    Fischetti, V.A.3    Ehrlich, S.D.4    Fons, M.5    Gruss, A.6
  • 20
    • 0031035974 scopus 로고    scopus 로고
    • High level heterologous protein production in Lactococcus and Lactobacillus using a new secretion system based on the Lactobacillus brevis S-layer signals
    • 1:CAS:528:DyaK2sXns1Sksw%3D%3D 9074504
    • Savijoki K, Kahala M, Palva A. High level heterologous protein production in Lactococcus and Lactobacillus using a new secretion system based on the Lactobacillus brevis S-layer signals. Gene. 1997;186(2):255-62.
    • (1997) Gene , vol.186 , Issue.2 , pp. 255-262
    • Savijoki, K.1    Kahala, M.2    Palva, A.3
  • 21
    • 0035464768 scopus 로고    scopus 로고
    • Signal peptide and propeptide optimization for heterologous protein secretion in Lactococcus lactis
    • 93138 11526014 10.1128/AEM.67.9.4119-4127.2001
    • Le Loir Y, Nouaille S, Commissaire J, Bretigny L, Gruss A, Langella P. Signal peptide and propeptide optimization for heterologous protein secretion in Lactococcus lactis. Appl Environ Microbiol. 2001;67(9):4119-27.
    • (2001) Appl Environ Microbiol , vol.67 , Issue.9 , pp. 4119-4127
    • Le Loir, Y.1    Nouaille, S.2    Commissaire, J.3    Bretigny, L.4    Gruss, A.5    Langella, P.6
  • 22
    • 0038404937 scopus 로고    scopus 로고
    • Prevalence of Escherichia coli O157:H7 and performance by beef feedlot cattle given Lactobacillus direct-fed microbials
    • 1:STN:280:DC%2BD3s3isFOmuw%3D%3D 12747680
    • Brashears MM, Galyean ML, Loneragan GH, Mann JE, Killinger-Mann K. Prevalence of Escherichia coli O157:H7 and performance by beef feedlot cattle given Lactobacillus direct-fed microbials. J Food Prot. 2003;66(5):748-54.
    • (2003) J Food Prot , vol.66 , Issue.5 , pp. 748-754
    • Brashears, M.M.1    Galyean, M.L.2    Loneragan, G.H.3    Mann, J.E.4    Killinger-Mann, K.5
  • 23
    • 0037339621 scopus 로고    scopus 로고
    • Isolation, selection, and characterization of lactic acid bacteria for a competitive exclusion product to reduce shedding of Escherichia coli O157:H7 in cattle
    • 1:CAS:528:DC%2BD3sXisVCksrY%3D 12636285
    • Brashears MM, Jaroni D, Trimble J. Isolation, selection, and characterization of lactic acid bacteria for a competitive exclusion product to reduce shedding of Escherichia coli O157:H7 in cattle. J Food Prot. 2003;66(3):355-63.
    • (2003) J Food Prot , vol.66 , Issue.3 , pp. 355-363
    • Brashears, M.M.1    Jaroni, D.2    Trimble, J.3
  • 24
    • 0031193607 scopus 로고    scopus 로고
    • Probiotic properties of lactic-acid bacteria: Plenty of scope for fundamental R & D
    • 1:CAS:528:DyaK2sXksFCgsbw%3D 9237406
    • Tannock GW. Probiotic properties of lactic-acid bacteria: plenty of scope for fundamental R & D. Trends Biotechnol. 1997;15(7):270-4.
    • (1997) Trends Biotechnol , vol.15 , Issue.7 , pp. 270-274
    • Tannock, G.W.1
  • 25
    • 0029941580 scopus 로고    scopus 로고
    • A new cell surface proteinase: Sequencing and analysis of the prtB gene from Lactobacillus delbruekii subsp. Bulgaricus
    • 1:CAS:528:DyaK28Xjt1Kmtro%3D 178052 8655480
    • Gilbert C, Atlan D, Blanc B, Portailer R, Germond JE, Lapierre L, et al. A new cell surface proteinase: sequencing and analysis of the prtB gene from Lactobacillus delbruekii subsp. bulgaricus. J Bacteriol. 1996;178(11):3059-65.
    • (1996) J Bacteriol , vol.178 , Issue.11 , pp. 3059-3065
    • Gilbert, C.1    Atlan, D.2    Blanc, B.3    Portailer, R.4    Germond, J.E.5    Lapierre, L.6
  • 26
    • 0035118294 scopus 로고    scopus 로고
    • Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum
    • 1:CAS:528:DC%2BD3MXitFGrtLc%3D 98054 11179325
    • Grangette C, Muller-Alouf H, Goudercourt D, Geoffroy MC, Turneer M, Mercenier A. Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum. Infect Immun. 2001;69(3):1547-53.
    • (2001) Infect Immun , vol.69 , Issue.3 , pp. 1547-1553
    • Grangette, C.1    Muller-Alouf, H.2    Goudercourt, D.3    Geoffroy, M.C.4    Turneer, M.5    Mercenier, A.6
  • 27
    • 11144231085 scopus 로고    scopus 로고
    • Intranasal immunisation using recombinant Lactobacillus johnsonii as a new strategy to prevent allergic disease
    • 1:CAS:528:DC%2BD2MXktVag 15629355
    • Scheppler L, Vogel M, Marti P, Muller L, Miescher SM, Stadler BM. Intranasal immunisation using recombinant Lactobacillus johnsonii as a new strategy to prevent allergic disease. Vaccine. 2005;23(9):1126-34.
    • (2005) Vaccine , vol.23 , Issue.9 , pp. 1126-1134
    • Scheppler, L.1    Vogel, M.2    Marti, P.3    Muller, L.4    Miescher, S.M.5    Stadler, B.M.6
  • 28
    • 0037178302 scopus 로고    scopus 로고
    • Recombinant Lactobacillus johnsonii as a mucosal vaccine delivery vehicle
    • 1:CAS:528:DC%2BD38XlsVOmtr4%3D 12126902
    • Scheppler L, Vogel M, Zuercher AW, Zuercher M, Germond JE, Miescher SM, et al. Recombinant Lactobacillus johnsonii as a mucosal vaccine delivery vehicle. Vaccine. 2002;20(23-24):2913-20.
    • (2002) Vaccine , vol.20 , Issue.23-24 , pp. 2913-2920
    • Scheppler, L.1    Vogel, M.2    Zuercher, A.W.3    Zuercher, M.4    Germond, J.E.5    Miescher, S.M.6
  • 29
    • 0033858446 scopus 로고    scopus 로고
    • Engineering the microflora to vaccinate the mucosa: Serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C-expressing lactobacilli
    • 1:CAS:528:DC%2BD3cXmtlejtrw%3D 2327037 10929079
    • Shaw DM, Gaerthe B, Leer RJ, Van Der Stap JG, Smittenaar C, Heijne Den Bak-Glashouwer M, et al. Engineering the microflora to vaccinate the mucosa: serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C-expressing lactobacilli. Immunology. 2000;100(4):510-8.
    • (2000) Immunology , vol.100 , Issue.4 , pp. 510-518
    • Shaw, D.M.1    Gaerthe, B.2    Leer, R.J.3    Van Der Stap, J.G.4    Smittenaar, C.5    Heijne Den Bak-Glashouwer, M.6
  • 30
    • 0032820970 scopus 로고    scopus 로고
    • Expression of the protective antigen of Bacillus anthracis by Lactobacillus casei: Towards the development of an oral vaccine against anthrax
    • 1:CAS:528:DyaK1MXmsFeqsrc%3D 10475978
    • Zegers ND, Kluter E, van Der Stap H, van Dura E, van Dalen P, Shaw M, et al. Expression of the protective antigen of Bacillus anthracis by Lactobacillus casei: towards the development of an oral vaccine against anthrax. J Appl Microbiol. 1999;87(2):309-14.
    • (1999) J Appl Microbiol , vol.87 , Issue.2 , pp. 309-314
    • Zegers, N.D.1    Kluter, E.2    Van Der Stap, H.3    Van Dura, E.4    Van Dalen, P.5    Shaw, M.6
  • 31
    • 0037820426 scopus 로고    scopus 로고
    • Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10
    • 1:CAS:528:DC%2BD3sXkvFertbk%3D 12808464
    • Steidler L, Neirynck S, Huyghebaert N, Snoeck V, Vermeire A, Goddeeris B, et al. Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10. Nat Biotechnol. 2003;21(7):785-9.
    • (2003) Nat Biotechnol , vol.21 , Issue.7 , pp. 785-789
    • Steidler, L.1    Neirynck, S.2    Huyghebaert, N.3    Snoeck, V.4    Vermeire, A.5    Goddeeris, B.6
  • 32
    • 0034714188 scopus 로고    scopus 로고
    • Treatment of murine colitis by Lactococcus lactis secreting interleukin-10
    • 1:CAS:528:DC%2BD3cXmt1amsLw%3D 10958782
    • Steidler L, Hans W, Schotte L, Neirynck S, Obermeier F, Falk W, et al. Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science. 2000;289(5483):1352-5.
    • (2000) Science , vol.289 , Issue.5483 , pp. 1352-1355
    • Steidler, L.1    Hans, W.2    Schotte, L.3    Neirynck, S.4    Obermeier, F.5    Falk, W.6
  • 33
    • 0031815046 scopus 로고    scopus 로고
    • Mucosal delivery of murine interleukin-2 (IL-2) and IL-6 by recombinant strains of Lactococcus lactis coexpressing antigen and cytokine
    • 1:CAS:528:DyaK1cXktFequ7w%3D 108331 9632584
    • Steidler L, Robinson K, Chamberlain L, Schofield KM, Remaut E, Le Page RW, et al. Mucosal delivery of murine interleukin-2 (IL-2) and IL-6 by recombinant strains of Lactococcus lactis coexpressing antigen and cytokine. Infect Immun. 1998;66(7):3183-9.
    • (1998) Infect Immun , vol.66 , Issue.7 , pp. 3183-3189
    • Steidler, L.1    Robinson, K.2    Chamberlain, L.3    Schofield, K.M.4    Remaut, E.5    Le Page, R.W.6
  • 34
    • 0028965668 scopus 로고
    • Secretion of biologically active murine interleukin-2 by Lactococcus lactis subsp. Lactis
    • 1:CAS:528:DyaK2MXksl2lt70%3D 167420 7747977
    • Steidler L, Wells JM, Raeymaekers A, Vandekerckhove J, Fiers W, Remaut E. Secretion of biologically active murine interleukin-2 by Lactococcus lactis subsp. lactis. Appl Environ Microbiol. 1995;61(4):1627-9.
    • (1995) Appl Environ Microbiol , vol.61 , Issue.4 , pp. 1627-1629
    • Steidler, L.1    Wells, J.M.2    Raeymaekers, A.3    Vandekerckhove, J.4    Fiers, W.5    Remaut, E.6
  • 35
    • 33646786067 scopus 로고    scopus 로고
    • Secretion of biologically active porcine interleukin-2 by Lactococcus lactis
    • 16549279
    • Avall-Jaaskelainen S, Palva A. Secretion of biologically active porcine interleukin-2 by Lactococcus lactis. Vet Microbiol. 2006;115(1-3):278-83.
    • (2006) Vet Microbiol , vol.115 , Issue.1-3 , pp. 278-283
    • Avall-Jaaskelainen, S.1    Palva, A.2
  • 36
    • 59649125330 scopus 로고    scopus 로고
    • Enhanced secretion of biologically active murine interleukin-12 by Lactococcus lactis
    • 1:CAS:528:DC%2BD1MXhvVWlsr8%3D 2632150 19060166
    • Fernandez A, Horn N, Wegmann U, Nicoletti C, Gasson MJ, Narbad A. Enhanced secretion of biologically active murine interleukin-12 by Lactococcus lactis. Appl Environ Microbiol. 2009;75(3):869-71.
    • (2009) Appl Environ Microbiol , vol.75 , Issue.3 , pp. 869-871
    • Fernandez, A.1    Horn, N.2    Wegmann, U.3    Nicoletti, C.4    Gasson, M.J.5    Narbad, A.6
  • 37
    • 0029063557 scopus 로고
    • Genetic marking of Lactococcus lactis shows its survival in the human gastrointestinal tract
    • 1:CAS:528:DyaK2MXms1GrsLw%3D 167550 7618890
    • Klijn N, Weerkamp AH, de Vos WM. Genetic marking of Lactococcus lactis shows its survival in the human gastrointestinal tract. Appl Environ Microbiol. 1995;61(7):2771-4.
    • (1995) Appl Environ Microbiol , vol.61 , Issue.7 , pp. 2771-2774
    • Klijn, N.1    Weerkamp, A.H.2    De Vos, W.M.3
  • 38
    • 33645031482 scopus 로고    scopus 로고
    • Oral delivery of beta-lactamase by Lactococcus lactis subsp. Lactis transformed with Plasmid ss80
    • 1:CAS:528:DC%2BD28XisFeqtbs%3D 16451824
    • Kaushal G, Shao J. Oral delivery of beta-lactamase by Lactococcus lactis subsp. lactis transformed with Plasmid ss80. Int J Pharm. 2006;312(1-2):90-5.
    • (2006) Int J Pharm , vol.312 , Issue.1-2 , pp. 90-95
    • Kaushal, G.1    Shao, J.2
  • 39
    • 14844307064 scopus 로고    scopus 로고
    • Differential binding specificities of oral streptococcal antigen I/II family adhesins for human or bacterial ligands
    • 1:CAS:528:DC%2BD2MXitl2ru7k%3D 15720563
    • Jakubovics NS, Stromberg N, van Dolleweerd CJ, Kelly CG, Jenkinson HF. Differential binding specificities of oral streptococcal antigen I/II family adhesins for human or bacterial ligands. Mol Microbiol. 2005;55(5):1591-605.
    • (2005) Mol Microbiol , vol.55 , Issue.5 , pp. 1591-1605
    • Jakubovics, N.S.1    Stromberg, N.2    Van Dolleweerd, C.J.3    Kelly, C.G.4    Jenkinson, H.F.5
  • 40
    • 0027230871 scopus 로고
    • Improved cloning vectors and transformation procedure for Lactococcus lactis
    • 1:CAS:528:DyaK3sXmtFylsrw%3D 8349525
    • Wells JM, Wilson PW, Le Page RW. Improved cloning vectors and transformation procedure for Lactococcus lactis. J Appl Bacteriol. 1993;74(6):629-36.
    • (1993) J Appl Bacteriol , vol.74 , Issue.6 , pp. 629-636
    • Wells, J.M.1    Wilson, P.W.2    Le Page, R.W.3
  • 41
    • 1442324848 scopus 로고    scopus 로고
    • Transepithelial electrical resistance is not a reliable measurement of the Caco-2 monolayer integrity in Transwell
    • 1:CAS:528:DC%2BD2cXis1Knu7Y%3D 15168786
    • Mukherjee T, Squillantea E, Gillespieb M, Shao J. Transepithelial electrical resistance is not a reliable measurement of the Caco-2 monolayer integrity in Transwell. Drug Deliv. 2004;11(1):11-8.
    • (2004) Drug Deliv , vol.11 , Issue.1 , pp. 11-18
    • Mukherjee, T.1    Squillantea, E.2    Gillespieb, M.3    Shao, J.4
  • 42
    • 0025732815 scopus 로고
    • A model of human small intestinal absorptive cells. 1. Transport barrier
    • 1:CAS:528:DyaK3MXhtF2isLs%3D 2023869
    • Cogburn JN, Donovan MG, Schasteen CS. A model of human small intestinal absorptive cells. 1. Transport barrier. Pharm Res. 1991;8(2):210-6.
    • (1991) Pharm Res , vol.8 , Issue.2 , pp. 210-216
    • Cogburn, J.N.1    Donovan, M.G.2    Schasteen, C.S.3
  • 43
    • 42349105761 scopus 로고    scopus 로고
    • Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria
    • 1:CAS:528:DC%2BD1cXkvVSms7o%3D 18345021
    • Wells JM, Mercenier A. Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria. Nat Rev Microbiol. 2008;6(5):349-62.
    • (2008) Nat Rev Microbiol , vol.6 , Issue.5 , pp. 349-362
    • Wells, J.M.1    Mercenier, A.2
  • 44
    • 0032949615 scopus 로고    scopus 로고
    • MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening
    • 1:CAS:528:DyaK1cXns1ylurk%3D 9874698
    • Irvine JD, Takahashi L, Lockhart K, Cheong J, Tolan JW, Selick HE, et al. MDCK (Madin-Darby canine kidney) cells: a tool for membrane permeability screening. J Pharm Sci. 1999;88(1):28-33.
    • (1999) J Pharm Sci , vol.88 , Issue.1 , pp. 28-33
    • Irvine, J.D.1    Takahashi, L.2    Lockhart, K.3    Cheong, J.4    Tolan, J.W.5    Selick, H.E.6
  • 45
    • 27144541896 scopus 로고    scopus 로고
    • The potential of chitosan for the oral administration of peptides
    • 1:CAS:528:DC%2BD2MXpvFOrtbs%3D 16296782
    • Prego C, Torres D, Alonso MJ. The potential of chitosan for the oral administration of peptides. Expert Opin Drug Deliv. 2005;2(5):843-54.
    • (2005) Expert Opin Drug Deliv , vol.2 , Issue.5 , pp. 843-854
    • Prego, C.1    Torres, D.2    Alonso, M.J.3
  • 46
    • 0035287318 scopus 로고    scopus 로고
    • Delivery systems for penetration enhancement of peptide and protein drugs: Design considerations
    • 1:CAS:528:DC%2BD3MXitVOhsLg%3D 11259842
    • Kompella UB, Lee VH. Delivery systems for penetration enhancement of peptide and protein drugs: design considerations. Adv Drug Deliv Rev. 2001;46(1-3):211-45.
    • (2001) Adv Drug Deliv Rev , vol.46 , Issue.1-3 , pp. 211-245
    • Kompella, U.B.1    Lee, V.H.2
  • 47
    • 28044461993 scopus 로고    scopus 로고
    • Strategies to improve oral drug bioavailability
    • 1:CAS:528:DC%2BD2MXlsFShsb4%3D 16296764
    • Gomez-Orellana I. Strategies to improve oral drug bioavailability. Expert Opin Drug Deliv. 2005;2(3):419-33.
    • (2005) Expert Opin Drug Deliv , vol.2 , Issue.3 , pp. 419-433
    • Gomez-Orellana, I.1


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