Antitumor activity of tatariside F isolated from roots of Fagopyrum tataricum (L.) Gaertn against H22 hepatocellular carcinoma via up-regulation of p53

Phytomedicine

Volumn 22, Issue 7-8, 2015, Pages 730-736

  Peng, Wei ^a,b   Hu, Changling ^a,c   Shu, Zhiheng ^a   Han, Ting ^a   Qin, Luping ^a   Zheng, Chengjian ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

Apoptosis; Fagopyrum tataricum (L.) Gaertn; H22 cell line; Hepatocellular carcinoma; p53; Tatariside F

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; GLUTATHIONE; MALONALDEHYDE; NATURAL PRODUCT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MDM2; PROTEIN P53; SUPEROXIDE DISMUTASE; TATARISIDE F; UNCLASSIFIED DRUG; BAX PROTEIN, HUMAN; BCL2 PROTEIN, HUMAN; FLAVONOID; TP53 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENTIATION; FAGOPYRUM; FAGOPYRUM TATARICUM; FLUORESCENCE POLARIZATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; LIVER INJURY; LIVER PROTECTION; MOUSE; NONHUMAN; PLANT ROOT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING; ANIMAL; APOPTOSIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; LIVER; LIVER TUMOR; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

FAGOPYRUM TATARICUM; MUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; FAGOPYRUM; FLAVONOIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER; LIVER NEOPLASMS; MICE; MICE, INBRED ICR; MOLECULAR STRUCTURE; PLANT ROOTS; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84935905806     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2015.05.003     Document Type: Article

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