-
1
-
-
57049114832
-
The genetics of the p53 pathway, apoptosis and cancer therapy
-
Vazquez, A., Bond, E. E., Levine, A. J. & Bond, G. L. The genetics of the p53 pathway, apoptosis and cancer therapy. Nat. Rev. Drug Discov. 7, 979-987 (2008).
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 979-987
-
-
Vazquez, A.1
Bond, E.E.2
Levine, A.J.3
Bond, G.L.4
-
2
-
-
0034703742
-
P53: Death star
-
Vousden, K. H. p53: death star. Cell 103, 691-694 (2000).
-
(2000)
Cell
, vol.103
, pp. 691-694
-
-
Vousden, K.H.1
-
3
-
-
4944255743
-
Post-translational modification of p53 in tumorigenesis
-
Bode, A. M. & Dong, Z. Post-translational modification of p53 in tumorigenesis. Nat. Rev. Cancer 4, 793-805 (2004).
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
4
-
-
65549120715
-
Modes of p53 regulation
-
Kruse, J. P. & Gu, W. Modes of p53 regulation. Cell 137, 609-622 (2009).
-
(2009)
Cell
, vol.137
, pp. 609-622
-
-
Kruse, J.P.1
Gu, W.2
-
5
-
-
0027325132
-
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
-
Oliner, J. D. et al. Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53. Nature 362, 857-860 (1993).
-
(1993)
Nature
, vol.362
, pp. 857-860
-
-
Oliner, J.D.1
-
6
-
-
0037112901
-
MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation
-
Ito, A. et al. MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation. EMBO J. 21, 6236-6245 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 6236-6245
-
-
Ito, A.1
-
7
-
-
77952744948
-
Suppression of histone deacetylase 3 (HDAC3) enhances apoptosis induced by paclitaxel in human maxillary cancer cells in vitro and in vivo
-
Narita, N. et al. Suppression of histone deacetylase 3 (HDAC3) enhances apoptosis induced by paclitaxel in human maxillary cancer cells in vitro and in vivo. Biochem. Biophys. Res. Commun. 396, 310-316 (2010).
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.396
, pp. 310-316
-
-
Narita, N.1
-
8
-
-
33749027242
-
HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells
-
Zeng, L. et al. HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells. J. Cell Biol. 174, 1059-1069 (2006).
-
(2006)
J. Cell Biol.
, vol.174
, pp. 1059-1069
-
-
Zeng, L.1
-
9
-
-
33746610114
-
MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents
-
Monte, M. et al. MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. Proc. Natl Acad. Sci. USA 103, 11160-11165 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 11160-11165
-
-
Monte, M.1
-
10
-
-
84907495054
-
MiR-326-Histone deacetylase-3 feedback loop regulates the invasion and tumorigenic and angiogenic response to anti-cancer drugs
-
Kim, Y. et al. miR-326-Histone deacetylase-3 feedback loop regulates the invasion and tumorigenic and angiogenic response to anti-cancer drugs. J. Biol. Chem. 289, 28019-28039 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 28019-28039
-
-
Kim, Y.1
-
11
-
-
33846202517
-
C-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis
-
Xia, Y. et al. c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis. Mol. Cell 25, 219-232 (2007).
-
(2007)
Mol. Cell
, vol.25
, pp. 219-232
-
-
Xia, Y.1
-
12
-
-
33846159473
-
Cleavage and cytoplasmic relocalization of histone deacetylase 3 are important for apoptosis progression
-
Escaffit, F. et al. Cleavage and cytoplasmic relocalization of histone deacetylase 3 are important for apoptosis progression. Mol. Cell. Biol. 27, 554-567 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 554-567
-
-
Escaffit, F.1
-
13
-
-
11144280578
-
Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data
-
Pilarsky, C., Wenzig, M., Specht, T., Saeger, H. D. & Grutzmann, R. Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia 6, 744-750 (2004).
-
(2004)
Neoplasia
, vol.6
, pp. 744-750
-
-
Pilarsky, C.1
Wenzig, M.2
Specht, T.3
Saeger, H.D.4
Grutzmann, R.5
-
14
-
-
0033534776
-
TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal
-
Liu, H. et al. TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal. Biochem. Biophys. Res. Commun. 254, 203-210 (1999).
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.254
, pp. 203-210
-
-
Liu, H.1
-
15
-
-
3543056889
-
The unique transcriptome through day 3 of human preimplantation development
-
Dobson, A. T. et al. The unique transcriptome through day 3 of human preimplantation development. Hum. Mol. Genet. 13, 1461-1470 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1461-1470
-
-
Dobson, A.T.1
-
16
-
-
54549113137
-
Reduced expression of PDCD5 is associated with high-grade astrocytic gliomas
-
Li, H. et al. Reduced expression of PDCD5 is associated with high-grade astrocytic gliomas. Oncol. Rep. 20, 573-579 (2008).
-
(2008)
Oncol. Rep.
, vol.20
, pp. 573-579
-
-
Li, H.1
-
17
-
-
33645801183
-
Association of the PDCD5 locus with lung cancer risk and prognosis in smokers
-
Spinola, M. et al. Association of the PDCD5 locus with lung cancer risk and prognosis in smokers. J. Clin. Oncol. 24, 1672-1678 (2006).
-
(2006)
J. Clin. Oncol.
, vol.24
, pp. 1672-1678
-
-
Spinola, M.1
-
18
-
-
33745018898
-
Expression of programmed cell death 5 gene involves in regulation of apoptosis in gastric tumor cells
-
Yang, Y. H. et al. Expression of programmed cell death 5 gene involves in regulation of apoptosis in gastric tumor cells. Apoptosis 11, 993-1001 (2006).
-
(2006)
Apoptosis
, vol.11
, pp. 993-1001
-
-
Yang, Y.H.1
-
19
-
-
84864289667
-
Transfection of PDCD5 effect on the biological behavior of tumor cells and sensitized gastric cancer cells to cisplatin-induced apoptosis
-
Xu, H. Y. et al. Transfection of PDCD5 effect on the biological behavior of tumor cells and sensitized gastric cancer cells to cisplatin-induced apoptosis. Dig. Dis. Sci. 57, 1847-1856 (2012).
-
(2012)
Dig. Dis. Sci.
, vol.57
, pp. 1847-1856
-
-
Xu, H.Y.1
-
20
-
-
78049288176
-
Transfection of PDCD5 sensitizes colorectal cancer cells to cisplatin-induced apoptosis in vitro and in vivo
-
Yin, A., Jiang, Y., Zhang, X., Zhao, J. & Luo, H. Transfection of PDCD5 sensitizes colorectal cancer cells to cisplatin-induced apoptosis in vitro and in vivo. Eur. J. Pharmacol. 649, 120-126 (2010).
-
(2010)
Eur. J. Pharmacol.
, vol.649
, pp. 120-126
-
-
Yin, A.1
Jiang, Y.2
Zhang, X.3
Zhao, J.4
Luo, H.5
-
21
-
-
65549141207
-
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis
-
Xu, L. et al. PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosis. Neoplasia 11, 345-354 (2009).
-
(2009)
Neoplasia
, vol.11
, pp. 345-354
-
-
Xu, L.1
-
22
-
-
2142848181
-
An alternative form of paraptosis-like cell death, triggered by TAJ/TROY and enhanced by PDCD5 overexpression
-
Wang, Y. et al. An alternative form of paraptosis-like cell death, triggered by TAJ/TROY and enhanced by PDCD5 overexpression. J. Cell Sci. 117, 1525-1532 (2004).
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1525-1532
-
-
Wang, Y.1
-
23
-
-
0037199869
-
Transfer of anti-TFAR19 monoclonal antibody into HeLa cells by in situ electroporation can inhibit the apoptosis
-
Rui, M., Chen, Y., Zhang, Y. & Ma, D. Transfer of anti-TFAR19 monoclonal antibody into HeLa cells by in situ electroporation can inhibit the apoptosis. Life Sci. 71, 1771-1778 (2002).
-
(2002)
Life Sci.
, vol.71
, pp. 1771-1778
-
-
Rui, M.1
Chen, Y.2
Zhang, Y.3
Ma, D.4
-
24
-
-
84868089289
-
PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway
-
Xu, L. et al. PDCD5 interacts with p53 and functions as a positive regulator in the p53 pathway. Apoptosis 17, 1235-1245 (2012).
-
(2012)
Apoptosis
, vol.17
, pp. 1235-1245
-
-
Xu, L.1
-
25
-
-
79960444448
-
Reversible SUMOylation of TBL1-TBLR1 regulates betacatenin-mediated Wnt signaling
-
Choi, H. K. et al. Reversible SUMOylation of TBL1-TBLR1 regulates betacatenin-mediated Wnt signaling. Mol. Cell 43, 203-216 (2011).
-
(2011)
Mol. Cell
, vol.43
, pp. 203-216
-
-
Choi, H.K.1
-
26
-
-
0034663815
-
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3
-
Li, J. et al. Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO J. 19, 4342-4350 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 4342-4350
-
-
Li, J.1
-
27
-
-
43049163953
-
Acetylation is indispensable for p53 activation
-
Tang, Y., Zhao, W., Chen, Y., Zhao, Y. & Gu, W. Acetylation is indispensable for p53 activation. Cell 133, 612-626 (2008).
-
(2008)
Cell
, vol.133
, pp. 612-626
-
-
Tang, Y.1
Zhao, W.2
Chen, Y.3
Zhao, Y.4
Gu, W.5
-
28
-
-
84927170688
-
The von Hippel-Lindau tumor suppressor regulates programmed cell death 5-mediated degradation of Mdm2
-
Essers, P. B. et al. The von Hippel-Lindau tumor suppressor regulates programmed cell death 5-mediated degradation of Mdm2. Oncogene 34, 771-779 (2014).
-
(2014)
Oncogene
, vol.34
, pp. 771-779
-
-
Essers, P.B.1
-
29
-
-
68249101883
-
Programmed cell death protein 5 (PDCD5) is phosphorylated by CK2 in vitro and in 293T cells
-
Salvi, M. et al. Programmed cell death protein 5 (PDCD5) is phosphorylated by CK2 in vitro and in 293T cells. Biochem. Biophys. Res. Commun. 387, 606-610 (2009).
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.387
, pp. 606-610
-
-
Salvi, M.1
-
30
-
-
78650333751
-
Phosphorylation meets nuclear import: A review
-
Nardozzi, J. D., Lott, K. & Cingolani, G. Phosphorylation meets nuclear import: a review. Cell Commun. Signal. 8, 32 (2010).
-
(2010)
Cell Commun. Signal.
, vol.8
, pp. 32
-
-
Nardozzi, J.D.1
Lott, K.2
Cingolani, G.3
-
31
-
-
84875445608
-
CDD: Conserved domains and protein threedimensional structure
-
Marchler-Bauer, A. et al. CDD: conserved domains and protein threedimensional structure. Nucleic Acids Res. 41, D348-D352 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D348-D352
-
-
Marchler-Bauer, A.1
-
32
-
-
78651377064
-
Clinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas
-
Zhang, X. et al. Clinical and prognostic significance of lost or decreased PDCD5 expression in human epithelial ovarian carcinomas. Oncol. Rep. 25, 353-358 (2011).
-
(2011)
Oncol. Rep.
, vol.25
, pp. 353-358
-
-
Zhang, X.1
-
33
-
-
79951571473
-
Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis
-
Zhang, F., Shi, Y., Wang, L. & Sriram, S. Role of HDAC3 on p53 expression and apoptosis in T cells of patients with multiple sclerosis. PLoS ONE 6, e16795 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e16795
-
-
Zhang, F.1
Shi, Y.2
Wang, L.3
Sriram, S.4
-
34
-
-
38949106130
-
Phosphorylation by casein kinase 2 regulates Nap1 localization and function
-
Calvert, M. E. et al. Phosphorylation by casein kinase 2 regulates Nap1 localization and function. Mol. Cell. Biol. 28, 1313-1325 (2008).
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 1313-1325
-
-
Calvert, M.E.1
-
35
-
-
68749103450
-
CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3
-
Mueller, T. et al. CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3. Hum. Mol. Genet. 18, 3334-3343 (2009).
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3334-3343
-
-
Mueller, T.1
-
36
-
-
70349320107
-
Protein kinase CK2 in health and disease: CK2: A key player in cancer biology
-
Trembley, J. H., Wang, G., Unger, G., Slaton, J. & Ahmed, K. Protein kinase CK2 in health and disease: CK2: a key player in cancer biology. Cell. Mol. life Sci. 66, 1858-1867 (2009).
-
(2009)
Cell. Mol. Life Sci.
, vol.66
, pp. 1858-1867
-
-
Trembley, J.H.1
Wang, G.2
Unger, G.3
Slaton, J.4
Ahmed, K.5
-
37
-
-
51349139607
-
Executioner caspase-3 and caspase-7 are functionally distinct proteases
-
Walsh, J. G. et al. Executioner caspase-3 and caspase-7 are functionally distinct proteases. Proc. Natl Acad. Sci. USA 105, 12815-12819 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 12815-12819
-
-
Walsh, J.G.1
-
38
-
-
79952773321
-
Phase II study of vorinostat for treatment of relapsed or refractory indolent non-Hodgkin's lymphoma and mantle cell lymphoma
-
Kirschbaum, M. et al. Phase II study of vorinostat for treatment of relapsed or refractory indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J. Clin. Oncol. 29, 1198-1203 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 1198-1203
-
-
Kirschbaum, M.1
-
39
-
-
84895815366
-
Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma
-
Minami, J. et al. Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma. Leukemia 28, 680-689 (2013).
-
(2013)
Leukemia
, vol.28
, pp. 680-689
-
-
Minami, J.1
-
40
-
-
84880715554
-
Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly
-
Suzuki, T. et al. Identification of highly selective and potent histone deacetylase 3 inhibitors using click chemistry-based combinatorial fragment assembly. PLoS ONE 8, e68669 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e68669
-
-
Suzuki, T.1
-
41
-
-
79952306399
-
COMPASS: A suite of pre- and post-search proteomics software tools for OMSSA
-
Wenger, C. D., Phanstiel, D. H., Lee, M. V., Bailey, D. J. & Coon, J. J. COMPASS: a suite of pre- and post-search proteomics software tools for OMSSA. Proteomics 11, 1064-1074 (2011).
-
(2011)
Proteomics
, vol.11
, pp. 1064-1074
-
-
Wenger, C.D.1
Phanstiel, D.H.2
Lee, M.V.3
Bailey, D.J.4
Coon, J.J.5
-
42
-
-
0037316303
-
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
-
Bolstad, B. M., Irizarry, R. A., Astrand, M. & Speed, T. P. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19, 185-193 (2003).
-
(2003)
Bioinformatics
, vol.19
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
Speed, T.P.4
-
43
-
-
84865304883
-
Nuclear receptor PPARgamma-regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis
-
Lee, Y. J. et al. Nuclear receptor PPARgamma-regulated monoacylglycerol O-acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis. Proc. Natl Acad. Sci. USA 109, 13656-13661 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 13656-13661
-
-
Lee, Y.J.1
-
44
-
-
34250378403
-
A protocol for rapid generation of recombinant adenoviruses using the AdEasy system
-
Luo, J. et al. A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat. Protoc. 2, 1236-1247 (2007).
-
(2007)
Nat. Protoc.
, vol.2
, pp. 1236-1247
-
-
Luo, J.1
|