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Volumn 22, Issue 8, 2015, Pages 1353-1362

TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFβ signaling activation

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NUCLEAR FACTOR; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR REST; TRANSFORMING GROWTH FACTOR BETA; TSPYL2 PROTEIN; TYROSINE KINASE RECEPTOR; TYROSINE KINASE RECEPTOR C; UNCLASSIFIED DRUG; NUCLEAR PROTEIN; RE1-SILENCING TRANSCRIPTION FACTOR; REPRESSOR PROTEIN; TSPYL2 PROTEIN, HUMAN;

EID: 84935687993     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.226     Document Type: Article
Times cited : (33)

References (40)
  • 1
    • 0028934541 scopus 로고
    • REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
    • Chong JA, Tapia-Ramirez J, Kim S, Toledo-Aral JJ, Zheng Y, Boutros MC et al. REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 1995; 80: 949-957.
    • (1995) Cell , vol.80 , pp. 949-957
    • Chong, J.A.1    Tapia-Ramirez, J.2    Kim, S.3    Toledo-Aral, J.J.4    Zheng, Y.5    Boutros, M.C.6
  • 2
    • 0028968802 scopus 로고
    • The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes
    • Schoenherr CJ, Anderson DJ. The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science 1995; 267: 1360-1363.
    • (1995) Science , vol.267 , pp. 1360-1363
    • Schoenherr, C.J.1    Anderson, D.J.2
  • 3
    • 19344378337 scopus 로고    scopus 로고
    • REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
    • Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 2005; 121: 645-657.
    • (2005) Cell , vol.121 , pp. 645-657
    • Ballas, N.1    Grunseich, C.2    Lu, D.D.3    Speh, J.C.4    Mandel, G.5
  • 4
    • 25844518743 scopus 로고    scopus 로고
    • The many faces of REST oversee epigenetic programming of neuronal genes
    • Ballas N, Mandel G. The many faces of REST oversee epigenetic programming of neuronal genes. Curr Opin Neurobiol 2005; 15: 500-506.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 500-506
    • Ballas, N.1    Mandel, G.2
  • 5
    • 33748921564 scopus 로고    scopus 로고
    • REST in good times and bad: Roles in tumor suppressor and oncogenic activities
    • Majumder S. REST in good times and bad: roles in tumor suppressor and oncogenic activities. Cell Cycle 2006; 5: 1929-1935.
    • (2006) Cell Cycle , vol.5 , pp. 1929-1935
    • Majumder, S.1
  • 7
    • 78049344289 scopus 로고    scopus 로고
    • Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer
    • Kreisler A, Strissel PL, Strick R, Neumann SB, Schumacher U, Becker CM. Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer. Oncogene 2010; 29: 5828-5838.
    • (2010) Oncogene , vol.29 , pp. 5828-5838
    • Kreisler, A.1    Strissel, P.L.2    Strick, R.3    Neumann, S.B.4    Schumacher, U.5    Becker, C.M.6
  • 10
    • 46949091848 scopus 로고    scopus 로고
    • Differentially expressed nucleolar transforming growth factor-beta1 target (DENTT) exhibits an inhibitory role on tumorigenesis
    • Kandalaft LE, Zudaire E, Portal-Nunez S, Cuttitta F, Jakowlew SB. Differentially expressed nucleolar transforming growth factor-beta1 target (DENTT) exhibits an inhibitory role on tumorigenesis. Carcinogenesis 2008; 29: 1282-1289.
    • (2008) Carcinogenesis , vol.29 , pp. 1282-1289
    • Kandalaft, L.E.1    Zudaire, E.2    Portal-Nunez, S.3    Cuttitta, F.4    Jakowlew, S.B.5
  • 11
    • 0035823486 scopus 로고    scopus 로고
    • SET-related cell division autoantigen-1 (CDA1) arrests cell growth
    • Chai Z, Sarcevic B, Mawson A, Toh BH. SET-related cell division autoantigen-1 (CDA1) arrests cell growth. J Biol Chem2001; 276: 33665-33674.
    • (2001) J Biol Chem , vol.276 , pp. 33665-33674
    • Chai, Z.1    Sarcevic, B.2    Mawson, A.3    Toh, B.H.4
  • 12
    • 34249694142 scopus 로고    scopus 로고
    • Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways
    • Tu Y, Wu W, Wu T, Cao Z, Wilkins R, Toh BH et al. Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways. J Biol Chem2007; 282: 11722-11731.
    • (2007) J Biol Chem , vol.282 , pp. 11722-11731
    • Tu, Y.1    Wu, W.2    Wu, T.3    Cao, Z.4    Wilkins, R.5    Toh, B.H.6
  • 13
    • 72449184034 scopus 로고    scopus 로고
    • Cell division autoantigen 1 plays a profibrotic role by modulating downstream signalling of TGF-beta in a murine diabetic model of atherosclerosis
    • Pham Y, Tu Y, Wu T, Allen TJ, Calkin AC, Watson AM et al. Cell division autoantigen 1 plays a profibrotic role by modulating downstream signalling of TGF-beta in a murine diabetic model of atherosclerosis. Diabetologia 2010; 53: 170-179.
    • (2010) Diabetologia , vol.53 , pp. 170-179
    • Pham, Y.1    Tu, Y.2    Wu, T.3    Allen, T.J.4    Calkin, A.C.5    Watson, A.M.6
  • 14
    • 78650881844 scopus 로고    scopus 로고
    • Cell division autoantigen 1 enhances signaling and the profibrotic effects of transforming growth factor-beta in diabetic nephropathy
    • Tu Y, Wu T, Dai A, Pham Y, Chew P, de Haan JB et al. Cell division autoantigen 1 enhances signaling and the profibrotic effects of transforming growth factor-beta in diabetic nephropathy. Kidney Int 2011; 79: 199-209.
    • (2011) Kidney Int , vol.79 , pp. 199-209
    • Tu, Y.1    Wu, T.2    Dai, A.3    Pham, Y.4    Chew, P.5    De Haan, J.B.6
  • 15
    • 18044387226 scopus 로고    scopus 로고
    • Differentially expressed nucleolar TGF-beta1 target (DENTT) shows tissue-specific nuclear and cytoplasmic localization and increases TGFbeta1-responsive transcription in primates
    • Ozbun LL, Martinez A, Jakowlew SB. Differentially expressed nucleolar TGF-beta1 target (DENTT) shows tissue-specific nuclear and cytoplasmic localization and increases TGFbeta1-responsive transcription in primates. Biochim Biophys Acta 2005; 1728: 163-180.
    • (2005) Biochim Biophys Acta , vol.1728 , pp. 163-180
    • Ozbun, L.L.1    Martinez, A.2    Jakowlew, S.B.3
  • 16
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
    • Siegel PM, Massague J. Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer 2003; 3: 807-821.
    • (2003) Nat Rev Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massague, J.2
  • 17
    • 0034785348 scopus 로고    scopus 로고
    • TGF-beta signaling in tumor suppression and cancer progression
    • Derynck R, Akhurst RJ, Balmain A. TGF-beta signaling in tumor suppression and cancer progression. Nat Genet 2001; 29: 117-129.
    • (2001) Nat Genet , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 18
  • 21
    • 77950865743 scopus 로고    scopus 로고
    • Xenopus RCOR2 (REST corepressor 2 interacts with ZMYND8, which is involved in neural differentiation
    • Zeng W, Kong Q, Li C, Mao B. Xenopus RCOR2 (REST corepressor 2) interacts with ZMYND8, which is involved in neural differentiation. Biochem Biophys Res Commun 2010; 394: 1024-1029.
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 1024-1029
    • Zeng, W.1    Kong, Q.2    Li, C.3    Mao, B.4
  • 22
    • 0035852637 scopus 로고    scopus 로고
    • CoREST is an integral component of the CoREST-human histone deacetylase complex
    • You A, Tong JK, Grozinger CM, Schreiber SL. CoREST is an integral component of the CoREST-human histone deacetylase complex. Proc Natl Acad Sci USA 2001; 98: 1454-1458.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1454-1458
    • You, A.1    Tong, J.K.2    Grozinger, C.M.3    Schreiber, S.L.4
  • 24
    • 0034001908 scopus 로고    scopus 로고
    • Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex
    • Roopra A, Sharling L, Wood IC, Briggs T, Bachfischer U, Paquette AJ et al. Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex. Mol Cell Biol 2000; 20: 2147-2157.
    • (2000) Mol Cell Biol , vol.20 , pp. 2147-2157
    • Roopra, A.1    Sharling, L.2    Wood, I.C.3    Briggs, T.4    Bachfischer, U.5    Paquette, A.J.6
  • 25
    • 0033598827 scopus 로고    scopus 로고
    • Neural restrictive silencer factor recruits mSin3 and histone deacetylase complex to repress neuron-specific target genes
    • Naruse Y, Aoki T, Kojima T, Mori N. Neural restrictive silencer factor recruits mSin3 and histone deacetylase complex to repress neuron-specific target genes. Proc Natl Acad Sci USA 1999; 96: 13691-13696.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13691-13696
    • Naruse, Y.1    Aoki, T.2    Kojima, T.3    Mori, N.4
  • 26
    • 0033306577 scopus 로고    scopus 로고
    • Transcriptional repression by REST: Recruitment of Sin3A and histone deacetylase to neuronal genes
    • Huang Y, Myers SJ, Dingledine R. Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes. Nat Neurosci 1999; 2: 867-872.
    • (1999) Nat Neurosci , vol.2 , pp. 867-872
    • Huang, Y.1    Myers, S.J.2    Dingledine, R.3
  • 27
    • 54049158139 scopus 로고    scopus 로고
    • Transforming growth factor-beta requires its target plasminogen activator inhibitor-1 for cytostatic activity
    • Kortlever RM, Nijwening JH, Bernards R. Transforming growth factor-beta requires its target plasminogen activator inhibitor-1 for cytostatic activity. J Biol Chem2008; 283: 24308-24313.
    • (2008) J Biol Chem , vol.283 , pp. 24308-24313
    • Kortlever, R.M.1    Nijwening, J.H.2    Bernards, R.3
  • 28
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J 1998; 17: 3091-3100.
    • (1998) EMBO J , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 29
    • 57049167675 scopus 로고    scopus 로고
    • CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation
    • Mulligan P, Westbrook TF, Ottinger M, Pavlova N, Chang B, Macia E et al. CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation. Mol Cell 2008; 32: 718-726.
    • (2008) Mol Cell , vol.32 , pp. 718-726
    • Mulligan, P.1    Westbrook, T.F.2    Ottinger, M.3    Pavlova, N.4    Chang, B.5    MacIa, E.6
  • 31
    • 36649021126 scopus 로고    scopus 로고
    • ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex
    • Li Z, Tognon CE, Godinho FJ, Yasaitis L, Hock H, Herschkowitz JI et al. ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex. Cancer Cell 2007; 12: 542-558.
    • (2007) Cancer Cell , vol.12 , pp. 542-558
    • Li, Z.1    Tognon, C.E.2    Godinho, F.J.3    Yasaitis, L.4    Hock, H.5    Herschkowitz, J.I.6
  • 32
    • 19044391610 scopus 로고    scopus 로고
    • Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma
    • Tognon C, Knezevich SR, Huntsman D, Roskelley CD, Melnyk N, Mathers JA et al. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell 2002; 2: 367-376.
    • (2002) Cancer Cell , vol.2 , pp. 367-376
    • Tognon, C.1    Knezevich, S.R.2    Huntsman, D.3    Roskelley, C.D.4    Melnyk, N.5    Mathers, J.A.6
  • 34
    • 0033557864 scopus 로고    scopus 로고
    • Fusion of ETV6 to neurotrophin-3 receptor TRKC in acute myeloid leukemia with t(12;15)( p13;q25)
    • Eguchi M, Eguchi-Ishimae M, Tojo A, Morishita K, Suzuki K, Sato Y et al. Fusion of ETV6 to neurotrophin-3 receptor TRKC in acute myeloid leukemia with t(12;15)(p13;q25). Blood 1999; 93: 1355-1363.
    • (1999) Blood , vol.93 , pp. 1355-1363
    • Eguchi, M.1    Eguchi-Ishimae, M.2    Tojo, A.3    Morishita, K.4    Suzuki, K.5    Sato, Y.6
  • 35
    • 36849008767 scopus 로고    scopus 로고
    • TrkC binds to the type II TGF-beta receptor to suppress TGF-beta signaling
    • Jin W, Yun C, Kwak MK, Kim TA, Kim SJ. TrkC binds to the type II TGF-beta receptor to suppress TGF-beta signaling. Oncogene 2007; 26: 7684-7691.
    • (2007) Oncogene , vol.26 , pp. 7684-7691
    • Jin, W.1    Yun, C.2    Kwak, M.K.3    Kim, T.A.4    Kim, S.J.5
  • 36
    • 28044451534 scopus 로고    scopus 로고
    • The ETV6-NTRK3 chimeric tyrosine kinase suppresses TGF-beta signaling by inactivating the TGF-beta type II receptor
    • Jin W, Kim BC, Tognon C, Lee HJ, Patel S, Lannon CL et al. The ETV6-NTRK3 chimeric tyrosine kinase suppresses TGF-beta signaling by inactivating the TGF-beta type II receptor. Proc Natl Acad Sci USA 2005; 102: 16239-16244.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 16239-16244
    • Jin, W.1    Kim, B.C.2    Tognon, C.3    Lee, H.J.4    Patel, S.5    Lannon, C.L.6
  • 37
    • 0035499364 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 enhances expression of brain-derived neurotrophic factor and its receptor, TrkB, in neurons cultured from rat cerebral cortex
    • Sometani A, Kataoka H, Nitta A, Fukumitsu H, Nomoto H, Furukawa S. Transforming growth factor-beta1 enhances expression of brain-derived neurotrophic factor and its receptor, TrkB, in neurons cultured from rat cerebral cortex. J Neurosci Res2001; 66: 369-376.
    • (2001) J Neurosci Res , vol.66 , pp. 369-376
    • Sometani, A.1    Kataoka, H.2    Nitta, A.3    Fukumitsu, H.4    Nomoto, H.5    Furukawa, S.6
  • 38
    • 0027136742 scopus 로고
    • Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1
    • Pierce DF Jr., Johnson MD, Matsui Y, Robinson SD, Gold LI, Purchio AF et al. Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1. Genes Dev1993; 7: 2308-2317.
    • (1993) Genes Dev , vol.7 , pp. 2308-2317
    • Pierce, D.F.1    Johnson, M.D.2    Matsui, Y.3    Robinson, S.D.4    Gold, L.I.5    Purchio, A.F.6
  • 40
    • 78149274357 scopus 로고    scopus 로고
    • TrkC plays an essential role in breast tumor growth and metastasis
    • Jin W, Kim GM, Kim MS, Lim MH, Yun C, Jeong J et al. TrkC plays an essential role in breast tumor growth and metastasis. Carcinogenesis 2010; 31: 1939-1947.
    • (2010) Carcinogenesis , vol.31 , pp. 1939-1947
    • Jin, W.1    Kim, G.M.2    Kim, M.S.3    Lim, M.H.4    Yun, C.5    Jeong, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.