Transforming growth factor-β requires its target plasminogen activator inhibitor-1 for cytostatic activity

Journal of Biological Chemistry

Volumn 283, Issue 36, 2008, Pages 24308-24313

  Kortlever, Roderik M ^a,b   Nijwening, Jeroen H ^a   Bernards, René ^a,c  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NONE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; CELL CULTURE; CHEMICAL ACTIVATION; ENZYME INHIBITION; FIBROBLASTS; GENE ENCODING; GENES; GROWTH (MATERIALS); NUCLEIC ACIDS; PEPTIDES; RNA; TARGETS;

ANTIPROLIFERATIVE ACTIVITIES; BONA FIDE; CYTOKINE; CYTOSTATIC ACTIVITIES; ECTOPIC EXPRESSIONS; GROWTH ARRESTS; HUMAN KERATINOCYTES; KNOCK OUTS; MOUSE EMBRYO FIBROBLASTS; ONCOGENESIS; PLASMINOGEN ACTIVATOR INHIBITORS; PROTEIN KINASES; RNA INTERFERENCES; SUSTAINED ACTIVATIONS; TARGET GENES; TRANSFORMING GROWTH FACTORS; TRANSFORMING GROWTHS; TUMOR PROGRESSIONS;

MOS CAPACITORS;

PHOSPHATIDYLINOSITOL 3 KINASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE B; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; SERINE PROTEINASE INHIBITOR; SERPINE1 PROTEIN, HUMAN; SERPINE2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSTASIS; ENZYME ACTIVITY; ENZYME REPRESSION; FIBROBLAST; GROWTH DISORDER; HUMAN; HUMAN CELL; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL LINE; CYTOLOGY; DRUG EFFECT; EMBRYO (ANATOMY); ENZYME ACTIVATION; METABOLISM; MOUSE MUTANT; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CELL LINE; CELL PROLIFERATION; EMBRYO, MAMMALIAN; ENZYME ACTIVATION; FIBROBLASTS; HUMANS; KERATINOCYTES; MICE; MICE, KNOCKOUT; PHOSPHORYLATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SERPINS; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 54049158139     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803341200     Document Type: Article

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