Osthole suppresses the proliferation and accelerates the apoptosis of human glioma cells via the upregulation of microRNA-16 and downregulation of MMP-9

Molecular Medicine Reports

Volumn 12, Issue 3, 2015, Pages 4592-4597

  Lin, Kai ^a   Gao, Zhiyu ^a   Shang, Bin ^b   Sui, Shaohua ^a   Fu, Qiang ^a  

^a TAISHAN MEDICAL UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF NORTH SICHUAN MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; Glioma cells; Matrix metalloproteinase 9; microRNA 16; Osthole; Proliferation

Indexed keywords

CASPASE 3; GELATINASE B; MICRORNA 16; OSTHOLE; RNA PRECURSOR; ANTINEOPLASTIC AGENT; COUMARIN DERIVATIVE; MICRORNA; MIRN16 MICRORNA, HUMAN; PLANT EXTRACT;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GLIOMA CELL; GLIOMA CELL LINE; HUMAN; HUMAN CELL; MTT ASSAY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ZYMOGRAPHY; AGONISTS; APIACEAE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; GLIA; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APIACEAE; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MATRIX METALLOPROTEINASE 9; MICRORNAS; NEUROGLIA; PLANT EXTRACTS; SIGNAL TRANSDUCTION;

EID: 84935500702     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3929     Document Type: Article

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