MiR-16-1 Plays a Role in Reducing Migration and Invasion of Glioma Cells

Anatomical Record

Volumn 296, Issue 3, 2013, Pages 427-432

  Li, Xiangdong ^a   Ling, Nan ^a   Bai, Yanyan ^b   Dong, Wanli ^a   Hui, Guo Zhen ^a   Liu, Dinghua ^b   Zhao, Jun ^c,d   Hu, Jin ^e  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b Affiliated Jiangyin Hospital of Southest University   (China)

^c SOOCHOW UNIVERSITY   (China)

^d Suzhou Key Laboratory for Molecular Cancer Genetics   (China)

^e FUDAN UNIVERSITY   (China)

Author keywords

Glioma; Invasion; Migration; MiR 16 1; Zyxin

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; MICRORNA 16; MICRORNA 16-1; UNCLASSIFIED DRUG; ZYXIN;

APOPTOSIS; ARTICLE; ASSAY; CANCER CELL CULTURE; CANCER INVASION; CELL MOTILITY; CELL PROLIFERATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WOUND HEALING;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; MICRORNAS; NEOPLASM INVASIVENESS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA STABILITY; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; ZYXIN;

EID: 84873749921     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.22626     Document Type: Article

References (26)

1. Bonci D, Coppola V, Musumeci M, Addario A, Giuffrida R, Memeo L, D'Urso L, Pagliuca A, Biffoni M, Labbaye C, Bartucci M, Muto G, Peschle C, De Maria R. 2008.The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 14:1271-1277.
2. Bottoni A, Piccin D, Tagliati F, Luchin A, Zatelli MC, degli Uberti EC. 2005.MiR-15a and miR-16-1 down-regulation in pituitary adenomas. J Cell Physiol 204:280-285.
3. Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E, Aldler H, Rattan S, Keating M, Rai K, Rassenti L, Kipps T, Negrini M, Bullrich F, Croce CM. 2002.Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99:15524-15529.
4. Calin GA, Liu CG, Sevignani C, Ferracin M, Felli N, Dumitru CD, Shimizu M, Cimmino A, Zupo S, Dono M, Dell'Aquila ML, Alder H, Rassenti L, Kipps TJ, Bullrich F, Negrini M, Croce CM. 2004.MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA 101:11755-11760.
5. Chan JA, Krichevsky AM, Kosik KS. 2005.MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65:6029-6033.
6. Chao TF, Zhang Y, Yan XQ, Yin B, Gong YH, Yuan JG, Qiang BQ, Peng XZ. 2008.[MiR-9 regulates the expression of CBX7 in human glioma]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 30:268-274.
7. Ciafre SA, Galardi S, Mangiola A, Ferracin M, Liu CG, Sabatino G, Negrini M, Maira G, Croce CM, Farace MG. 2005.Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem Biophys Res Commun 334:1351-1358.
8. Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, Shimizu M, Wojcik SE, Aqeilan RI, Zupo S, Dono M, Rassenti L, Alder H, Volinia S, Liu CG, Kipps TJ, Negrini M, Croce CM. 2005.miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102:13944-13949.
9. Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K. 2007.MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res 67:8994-9000.
10. Dillhoff M, Liu J, Frankel W, Croce C, Bloomston M. 2008.MicroRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival. J Gastrointest Surg 12:2171-2176.
11. Gillies JK, Lorimer IA. 2007.Regulation of p27Kip1 by miRNA 221/222 in glioblastoma. Cell Cycle 6:2005-2009.
12. Gregory RI, Shiekhattar R. 2005.MicroRNA biogenesis and cancer. Cancer Res 65:3509-3512.
13. Kefas B, Godlewski J, Comeau L, Li Y, Abounader R, Hawkinson M, Lee J, Fine H, Chiocca EA, Lawler S, Purow B. 2008.microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res 68:3566-3572.
14. Linsley PS, Schelter J, Burchard J, Kibukawa M, Martin MM, Bartz SR, Johnson JM, Cummins JM, Raymond CK, Dai H, Chau N, Cleary M, Jackson AL, Carleton M, Lim L. 2007.Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression. Mol Cell Biol 27:2240-2252.
15. Liu T, Papagiannakopoulos T, Puskar K, Qi S, Santiago F, Clay W, Lao K, Lee Y, Nelson SF, Kornblum HI, Doyle F, Petzold L, Shraiman B, Kosik KS. 2007.Detection of a microRNA signal in an in vivo expression set of mRNAs. PLoS One 2:e804.
16. Ma L, Weinberg RA. 2008.Micromanagers of malignancy: role of microRNAs in regulating metastasis. Trends Genet 24:448-456.
17. Medina R, Zaidi SK, Liu CG, Stein JL, van Wijnen AJ, Croce CM, Stein GS. 2008.MicroRNAs 221 and 222 bypass quiescence and compromise cell survival. Cancer Res 68:2773-2780.
18. Miller CR, Perry A. 2007.Glioblastoma. Arch Pathol Lab Med 131:397-406.
19. Rivas MA, Venturutti L, Huang YW, Schillaci R, Huang TH, Elizalde PV. 2012.Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer development. Breast Cancer Res 14:R77.
20. Shi L, Cheng Z, Zhang J, Li R, Zhao P, Fu Z, You Y. 2008.hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells. Brain Res 1236:185-193.
21. Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H, Harano T, Yatabe Y, Nagino M, Nimura Y, Mitsudomi T, Takahashi T. 2004.Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 64:3753-3756.
22. Wang X, Ling C, Bai Y, Zhao J. 2011.MicroRNA-206 is associated with invasion and metastasis of lung cancer. Anat Rec (Hoboken) 294:88-92.
23. Wang X, Tang S, Le SY, Lu R, Rader JS, Meyers C, Zheng ZM. 2008.Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS One 3:e2557.
24. Wu H, Liu T, Wang R, Tian S, Liu M, Li X, Tang H. 2011.MicroRNA-16 targets zyxin and promotes cell motility in human laryngeal carcinoma cell line HEp-2. IUBMB Life 63:101-108.
25. Xia H, Qi Y, Ng SS, Chen X, Chen S, Fang M, Li D, Zhao Y, Ge R, Li G, Chen Y, He ML, Kung HF, Lai L, Lin MC. 2009.MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells. Biochem Biophys Res Commun 380:205-210.
26. Xia L, Zhang D, Du R, Pan Y, Zhao L, Sun S, Hong L, Liu J, Fan D. 2008.miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer 123:372-379.