Arterial endothelial methylome: Differential DNA methylation in athero-susceptible disturbed flow regions in vivo

BMC Genomics

Volumn 16, Issue 1, 2015, Pages

  Jiang, Yi Zhou ^a   Manduchi, Elisabetta ^a   Stoeckert, Christian J ^a   Davies, Peter F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Atherosclerosis; Disturbed flow; DNA methylation; Endothelial gene transcription; Endothelium; Epigenetics; Hemodynamics; HOX genes

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; DNA; HOX PROTEIN; HOXA PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 10A; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; TRANSCRIPTOME;

5' UNTRANSLATED REGION; ADULT; ALGORITHM; ANIMAL EXPERIMENT; AORTA ARCH; ARTERY ENDOTHELIUM; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; CPG ISLAND; CYTOSKELETON; DISEASE PREDISPOSITION; DNA METHYLATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; EPIGENETICS; EUKARYOTIC FLAGELLUM; EXON; FEMALE; FUNCTIONAL GENOMICS; GENE; GENE EXPRESSION; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HEMODYNAMICS; HOX GENE; HOXA GENE; IMMUNOPRECIPITATION; IN VIVO STUDY; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PHENOTYPE; PIG; POLYMERASE CHAIN REACTION; PRINCIPAL COMPONENT ANALYSIS; PROMOTER REGION; SPATIOTEMPORAL ANALYSIS; THORACIC AORTA; TRANSCRIPTION REGULATION; ANIMAL; AORTA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROCEDURES; VASCULAR ENDOTHELIUM;

SUIDAE;

ANIMALS; AORTA; ATHEROSCLEROSIS; CPG ISLANDS; DNA METHYLATION; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MALE; PHENOTYPE; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; SPATIO-TEMPORAL ANALYSIS; SWINE; TRANSCRIPTOME;

EID: 84935416856     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1656-4     Document Type: Article

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