Overactivation of NR2B-containing NMDA receptors through entorhinal-hippocampal connection initiates accumulation of hyperphosphorylated tau in rat hippocampus after transient middle cerebral artery occlusion

Journal of Neurochemistry

Volumn 134, Issue 3, 2015, Pages 566-577

  Xu, Cheng Shi ^a   Liu, An Chun ^b   Chen, Juan ^b   Pan, Zhi Yong ^a   Wan, Qi ^b   Li, Zhi Qiang ^a   Wang, Ze Fen ^b  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

Author keywords

hippocampus; ischemia; NMDA receptor; tau

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; IFENPRODIL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PROTEIN KINASE B; TAU PROTEIN; MAPT PROTEIN, RAT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR2B NMDA RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DEAFFERENTATION; ENTORHINAL CORTEX; ENZYME ACTIVITY; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; IMMUNOBLOTTING; LEARNING DISORDER; MALE; MEMORY DISORDER; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN HYPERPHOSPHORYLATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; RAT; SPATIAL LEARNING; SPATIAL MEMORY; TAUOPATHY; WESTERN BLOTTING; ANIMAL; CEREBRAL ARTERY DISEASE; HEMISPHERIC DOMINANCE; METABOLISM; NERVE TRACT; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; BLOTTING, WESTERN; ENTORHINAL CORTEX; FUNCTIONAL LATERALITY; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEURAL PATHWAYS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; TAU PROTEINS;

EID: 84935414475     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13134     Document Type: Article

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