-
1
-
-
84867896903
-
Transcriptional control of effector and memory CD8+ T cell differentiation
-
Kaech SM, Cui W. Transcriptional control of effector and memory CD8+ T cell differentiation. Nat Rev Immunol (2012) 12(11):749-61. doi: 10.1038/nri3307
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.11
, pp. 749-761
-
-
Kaech, S.M.1
Cui, W.2
-
2
-
-
34548683483
-
Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection
-
Kaech SM, Wherry EJ. Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. Immunity (2007) 27(3):393-405. doi:10.1016/j.immuni.2007.08.007
-
(2007)
Immunity
, vol.27
, Issue.3
, pp. 393-405
-
-
Kaech, S.M.1
Wherry, E.J.2
-
3
-
-
84911201387
-
Molecular regulation of effector and memory T cell differentiation
-
Chang JT, Wherry EJ, Goldrath AW. Molecular regulation of effector and memory T cell differentiation. Nat Immunol (2014) 15(12):1104-15. doi:10.1038/ni.3031
-
(2014)
Nat Immunol
, vol.15
, Issue.12
, pp. 1104-1115
-
-
Chang, J.T.1
Wherry, E.J.2
Goldrath, A.W.3
-
4
-
-
77649220954
-
Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells
-
O'Shea JJ, Paul WE. Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells. Science (2010) 327(5969):1098-102. doi:10.1126/science.1178334
-
(2010)
Science
, vol.327
, Issue.5969
, pp. 1098-1102
-
-
O'Shea, J.J.1
Paul, W.E.2
-
5
-
-
79959473134
-
T-bet in disease
-
Lazarevic V, Glimcher LH. T-bet in disease. Nat Immunol (2011) 12(7):597-606. doi:10.1038/ni.2059
-
(2011)
Nat Immunol
, vol.12
, Issue.7
, pp. 597-606
-
-
Lazarevic, V.1
Glimcher, L.H.2
-
6
-
-
80053063773
-
The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system
-
Beaulieu AM, Sant'Angelo DB. The BTB-ZF family of transcription factors: key regulators of lineage commitment and effector function development in the immune system. J Immunol (2011) 187(6):2841-7. doi:10.4049/jimmunol.1004006
-
(2011)
J Immunol
, vol.187
, Issue.6
, pp. 2841-2847
-
-
Beaulieu, A.M.1
Sant'Angelo, D.B.2
-
7
-
-
84906243997
-
The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function
-
Hogquist KA, Jameson SC. The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function. Nat Immunol (2014) 15(9):815-23. doi:10.1038/ni.2938
-
(2014)
Nat Immunol
, vol.15
, Issue.9
, pp. 815-823
-
-
Hogquist, K.A.1
Jameson, S.C.2
-
8
-
-
77953541634
-
Inflammatory cytokines as a third signal for T cell activation
-
Curtsinger JM, Mescher MF. Inflammatory cytokines as a third signal for T cell activation. Curr Opin Immunol (2010) 22(3):333-40. doi:10.1016/j.coi.2010.02.013
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.3
, pp. 333-340
-
-
Curtsinger, J.M.1
Mescher, M.F.2
-
9
-
-
79954459308
-
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family
-
Bour-Jordan H, Esensten JH, Martinez-Llordella M, Penaranda C, Stumpf M, Bluestone JA. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family. Immunol Rev (2011) 241(1):180-205. doi:10.1111/j.1600-065X.2011.01011.x
-
(2011)
Immunol Rev
, vol.241
, Issue.1
, pp. 180-205
-
-
Bour-Jordan, H.1
Esensten, J.H.2
Martinez-Llordella, M.3
Penaranda, C.4
Stumpf, M.5
Bluestone, J.A.6
-
10
-
-
85027948869
-
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells
-
Guy CS, Vignali KM, Temirov J, Bettini ML, Overacre AE, Smeltzer M, et al. Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nat Immunol (2013) 14(3):262-70. doi:10.1038/ni.2538
-
(2013)
Nat Immunol
, vol.14
, Issue.3
, pp. 262-270
-
-
Guy, C.S.1
Vignali, K.M.2
Temirov, J.3
Bettini, M.L.4
Overacre, A.E.5
Smeltzer, M.6
-
11
-
-
84886720433
-
The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells
-
Man K, Miasari M, Shi W, Xin A, Henstridge DC, Preston S, et al. The transcription factor IRF4 is essential for TCR affinity-mediated metabolic programming and clonal expansion of T cells. Nat Immunol (2013) 14(11):1155-65. doi:10.1038/ni.2710
-
(2013)
Nat Immunol
, vol.14
, Issue.11
, pp. 1155-1165
-
-
Man, K.1
Miasari, M.2
Shi, W.3
Xin, A.4
Henstridge, D.C.5
Preston, S.6
-
12
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang R, Dillon CP, Shi LZ, Milasta S, Carter R, Finkelstein D, et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity (2011) 35(6):871-82. doi:10.1016/j.immuni.2011.09.021
-
(2011)
Immunity
, vol.35
, Issue.6
, pp. 871-882
-
-
Wang, R.1
Dillon, C.P.2
Shi, L.Z.3
Milasta, S.4
Carter, R.5
Finkelstein, D.6
-
13
-
-
84876684375
-
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity
-
Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, et al. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat Immunol (2013) 14(5):489-99. doi:10.1038/ni.2570
-
(2013)
Nat Immunol
, vol.14
, Issue.5
, pp. 489-499
-
-
Kidani, Y.1
Elsaesser, H.2
Hock, M.B.3
Vergnes, L.4
Williams, K.J.5
Argus, J.P.6
-
14
-
-
84877710866
-
Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection
-
Tubo NJ, Pagan AJ, Taylor JJ, Nelson RW, Linehan JL, Ertelt JM, et al. Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection. Cell (2013) 153(4):785-96. doi:10.1016/j.cell.2013.04.007
-
(2013)
Cell
, vol.153
, Issue.4
, pp. 785-796
-
-
Tubo, N.J.1
Pagan, A.J.2
Taylor, J.J.3
Nelson, R.W.4
Linehan, J.L.5
Ertelt, J.M.6
-
15
-
-
84915766942
-
TCR signal quantity and quality in CD4 T cell differentiation
-
Tubo NJ, Jenkins MK. TCR signal quantity and quality in CD4 T cell differentiation. Trends Immunol (2014) 35(12):591-6. doi:10.1016/j.it.2014.09.008
-
(2014)
Trends Immunol
, vol.35
, Issue.12
, pp. 591-596
-
-
Tubo, N.J.1
Jenkins, M.K.2
-
16
-
-
79960446668
-
The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants
-
van Gisbergen KP, Klarenbeek PL, Kragten NA, Unger PP, Nieuwenhuis MB, Wensveen FM, et al. The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants. Immunity (2011) 35(1):97-108. doi:10.1016/j.immuni.2011.04.020
-
(2011)
Immunity
, vol.35
, Issue.1
, pp. 97-108
-
-
van Gisbergen, K.P.1
Klarenbeek, P.L.2
Kragten, N.A.3
Unger, P.P.4
Nieuwenhuis, M.B.5
Wensveen, F.M.6
-
17
-
-
33646181088
-
How TCRs bind MHCs, peptides, and coreceptors.
-
Rudolph MG, Stanfield RL, Wilson IA. How TCRs bind MHCs, peptides, and coreceptors. Annu Rev Immunol (2006) 24:419-66. doi:10.1146/annurev.immunol.23.021704.115658
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 419-466
-
-
Rudolph, M.G.1
Stanfield, R.L.2
Wilson, I.A.3
-
18
-
-
84866562625
-
Metabolic checkpoints in activated T cells
-
Wang R, Green DR. Metabolic checkpoints in activated T cells. Nat Immunol (2012) 13(10):907-15. doi:10.1038/ni.2386
-
(2012)
Nat Immunol
, vol.13
, Issue.10
, pp. 907-915
-
-
Wang, R.1
Green, D.R.2
-
19
-
-
77953534607
-
Metabolism in T cell activation and differentiation
-
Pearce EL. Metabolism in T cell activation and differentiation. Curr Opin Immunol (2010) 22(3):314-20. doi:10.1016/j.coi.2010.01.018
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.3
, pp. 314-320
-
-
Pearce, E.L.1
-
20
-
-
84871861969
-
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells
-
Finlay DK, Rosenzweig E, Sinclair LV, Feijoo-Carnero C, Hukelmann JL, Rolf J, et al. PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells. J Exp Med (2012) 209(13):2441-53. doi:10.1084/jem.20112607
-
(2012)
J Exp Med
, vol.209
, Issue.13
, pp. 2441-2453
-
-
Finlay, D.K.1
Rosenzweig, E.2
Sinclair, L.V.3
Feijoo-Carnero, C.4
Hukelmann, J.L.5
Rolf, J.6
-
21
-
-
67650096912
-
Enhancing CD8 T-cell memory by modulating fatty acid metabolism
-
Pearce EL, Walsh MC, Cejas PJ, Harms GM, Shen H, Wang LS, et al. Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature (2009) 460(7251):103-7. doi:10.1038/nature08097
-
(2009)
Nature
, vol.460
, Issue.7251
, pp. 103-107
-
-
Pearce, E.L.1
Walsh, M.C.2
Cejas, P.J.3
Harms, G.M.4
Shen, H.5
Wang, L.S.6
-
22
-
-
84906274052
-
c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells
-
Chou C, Pinto AK, Curtis JD, Persaud SP, Cella M, Lin CC, et al. c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells. Nat Immunol (2014) 15(9):884-93. doi:10.1038/ni.2943
-
(2014)
Nat Immunol
, vol.15
, Issue.9
, pp. 884-893
-
-
Chou, C.1
Pinto, A.K.2
Curtis, J.D.3
Persaud, S.P.4
Cella, M.5
Lin, C.C.6
-
23
-
-
84867363219
-
TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation
-
Nayar R, Enos M, Prince A, Shin H, Hemmers S, Jiang JK, et al. TCR signaling via Tec kinase ITK and interferon regulatory factor 4 (IRF4) regulates CD8+ T-cell differentiation. Proc Natl Acad Sci U S A (2012) 109(41):E2794-802. doi:10.1073/pnas.1205742109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.41
, pp. E2794-E2802
-
-
Nayar, R.1
Enos, M.2
Prince, A.3
Shin, H.4
Hemmers, S.5
Jiang, J.K.6
-
24
-
-
84886672916
-
Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen
-
Doedens AL, Phan AT, Stradner MH, Fujimoto JK, Nguyen JV, Yang E, et al. Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen. Nat Immunol (2013) 14(11):1173-82. doi:10.1038/ni.2714
-
(2013)
Nat Immunol
, vol.14
, Issue.11
, pp. 1173-1182
-
-
Doedens, A.L.1
Phan, A.T.2
Stradner, M.H.3
Fujimoto, J.K.4
Nguyen, J.V.5
Yang, E.6
-
25
-
-
84887507709
-
Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation
-
Yao S, Buzo BF, Pham D, Jiang L, Taparowsky EJ, Kaplan MH, et al. Interferon regulatory factor 4 sustains CD8(+) T cell expansion and effector differentiation. Immunity (2013) 39(5):833-45. doi:10.1016/j.immuni.2013.10.007
-
(2013)
Immunity
, vol.39
, Issue.5
, pp. 833-845
-
-
Yao, S.1
Buzo, B.F.2
Pham, D.3
Jiang, L.4
Taparowsky, E.J.5
Kaplan, M.H.6
-
26
-
-
84902169111
-
Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection
-
Nayar R, Schutten E, Bautista B, Daniels K, Prince AL, Enos M, et al. Graded levels of IRF4 regulate CD8+ T cell differentiation and expansion, but not attrition, in response to acute virus infection. J Immunol (2014) 192(12):5881-93. doi:10.4049/jimmunol.1303187
-
(2014)
J Immunol
, vol.192
, Issue.12
, pp. 5881-5893
-
-
Nayar, R.1
Schutten, E.2
Bautista, B.3
Daniels, K.4
Prince, A.L.5
Enos, M.6
-
27
-
-
84876758617
-
Metabolic pathways in immune cell activation and quiescence
-
Pearce EL, Pearce EJ. Metabolic pathways in immune cell activation and quiescence. Immunity (2013) 38(4):633-43. doi:10.1016/j.immuni.2013.04.005
-
(2013)
Immunity
, vol.38
, Issue.4
, pp. 633-643
-
-
Pearce, E.L.1
Pearce, E.J.2
-
28
-
-
84911132031
-
Bcl-6 directly represses the gene program of the glycolysis pathway
-
Oestreich KJ, Read KA, Gilbertson SE, Hough KP, McDonald PW, Krishnamoorthy V, et al. Bcl-6 directly represses the gene program of the glycolysis pathway. Nat Immunol (2014) 15(10):957-64. doi:10.1038/ni.2985
-
(2014)
Nat Immunol
, vol.15
, Issue.10
, pp. 957-964
-
-
Oestreich, K.J.1
Read, K.A.2
Gilbertson, S.E.3
Hough, K.P.4
McDonald, P.W.5
Krishnamoorthy, V.6
-
29
-
-
84922069504
-
Bcl-6 gets T cells off the sugar
-
Man K, Kallies A. Bcl-6 gets T cells off the sugar. Nat Immunol (2014) 15(10):904-5. doi:10.1038/ni.2993
-
(2014)
Nat Immunol
, vol.15
, Issue.10
, pp. 904-905
-
-
Man, K.1
Kallies, A.2
-
30
-
-
65549115862
-
Plasticity of CD4+ T cell lineage differentiation
-
Zhou L, Chong MM, Littman DR. Plasticity of CD4+ T cell lineage differentiation. Immunity (2009) 30(5):646-55. doi:10.1016/j.immuni.2009.05.001
-
(2009)
Immunity
, vol.30
, Issue.5
, pp. 646-655
-
-
Zhou, L.1
Chong, M.M.2
Littman, D.R.3
-
31
-
-
84867894231
-
Master regulators or lineage-specifying? Changing views on CD4(+) T cell transcription factors
-
Oestreich KJ, Weinmann AS. Master regulators or lineage-specifying? Changing views on CD4(+) T cell transcription factors. Nat Rev Immunol (2012) 12(11):799-804. doi:10.1038/nri3321
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.11
, pp. 799-804
-
-
Oestreich, K.J.1
Weinmann, A.S.2
-
32
-
-
74549216531
-
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
-
Pipkin ME, Sacks JA, Cruz-Guilloty F, Lichtenheld MG, Bevan MJ, Rao A. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity (2010) 32(1):79-90. doi:10.1016/j.immuni.2009.11.012
-
(2010)
Immunity
, vol.32
, Issue.1
, pp. 79-90
-
-
Pipkin, M.E.1
Sacks, J.A.2
Cruz-Guilloty, F.3
Lichtenheld, M.G.4
Bevan, M.J.5
Rao, A.6
-
33
-
-
84858706847
-
Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
-
Oestreich KJ, Mohn SE, Weinmann AS. Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile. Nat Immunol (2012) 13(4):405-11. doi:10.1038/ni.2242
-
(2012)
Nat Immunol
, vol.13
, Issue.4
, pp. 405-411
-
-
Oestreich, K.J.1
Mohn, S.E.2
Weinmann, A.S.3
-
34
-
-
84867581744
-
A validated regulatory network for Th17 cell specification
-
Ciofani M, Madar A, Galan C, Sellars M, Mace K, Pauli F, et al. A validated regulatory network for Th17 cell specification. Cell (2012) 151(2):289-303. doi:10.1016/j.cell.2012.09.016
-
(2012)
Cell
, vol.151
, Issue.2
, pp. 289-303
-
-
Ciofani, M.1
Madar, A.2
Galan, C.3
Sellars, M.4
Mace, K.5
Pauli, F.6
-
35
-
-
84867861268
-
BATF-JUN is critical for IRF4-mediated transcription in T cells
-
Li P, Spolski R, Liao W, Wang L, Murphy TL, Murphy KM, et al. BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature (2012) 490(7421):543-6. doi:10.1038/nature11530
-
(2012)
Nature
, vol.490
, Issue.7421
, pp. 543-546
-
-
Li, P.1
Spolski, R.2
Liao, W.3
Wang, L.4
Murphy, T.L.5
Murphy, K.M.6
-
36
-
-
79960369458
-
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi LZ, Wang R, Huang G, Vogel P, Neale G, Green DR, et al. HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. J Exp Med (2011) 208(7):1367-76. doi:10.1084/jem.20110278
-
(2011)
J Exp Med
, vol.208
, Issue.7
, pp. 1367-1376
-
-
Shi, L.Z.1
Wang, R.2
Huang, G.3
Vogel, P.4
Neale, G.5
Green, D.R.6
-
37
-
-
82055177182
-
How T cells earn the follicular rite of passage
-
Vinuesa CG, Cyster JG. How T cells earn the follicular rite of passage. Immunity (2011) 35(5):671-80. doi:10.1016/j.immuni.2011.11.001
-
(2011)
Immunity
, vol.35
, Issue.5
, pp. 671-680
-
-
Vinuesa, C.G.1
Cyster, J.G.2
-
38
-
-
84886790466
-
T-bet: a bridge between innate and adaptive immunity
-
Lazarevic V, Glimcher LH, Lord GM. T-bet: a bridge between innate and adaptive immunity. Nat Rev Immunol (2013) 13(11):777-89. doi:10.1038/nri3536
-
(2013)
Nat Rev Immunol
, vol.13
, Issue.11
, pp. 777-789
-
-
Lazarevic, V.1
Glimcher, L.H.2
Lord, G.M.3
-
39
-
-
75649136214
-
Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
-
Crotty S, Johnston RJ, Schoenberger SP. Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat Immunol (2010) 11(2):114-20. doi:10.1038/ni.1837
-
(2010)
Nat Immunol
, vol.11
, Issue.2
, pp. 114-120
-
-
Crotty, S.1
Johnston, R.J.2
Schoenberger, S.P.3
-
40
-
-
82555190936
-
The genetic network controlling plasma cell differentiation
-
Nutt SL, Taubenheim N, Hasbold J, Corcoran LM, Hodgkin PD. The genetic network controlling plasma cell differentiation. Semin Immunol (2011) 23(5):341-9. doi:10.1016/j.smim.2011.08.010
-
(2011)
Semin Immunol
, vol.23
, Issue.5
, pp. 341-349
-
-
Nutt, S.L.1
Taubenheim, N.2
Hasbold, J.3
Corcoran, L.M.4
Hodgkin, P.D.5
-
41
-
-
84925969707
-
Metabolic pathways promoting cancer cell survival and growth
-
Boroughs LK, DeBerardinis RJ. Metabolic pathways promoting cancer cell survival and growth. Nat Cell Biol (2015) 17(4):351-9. doi:10.1038/ncb3124
-
(2015)
Nat Cell Biol
, vol.17
, Issue.4
, pp. 351-359
-
-
Boroughs, L.K.1
DeBerardinis, R.J.2
-
42
-
-
84906857361
-
ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis
-
Liu XS, Haines JE, Mehanna EK, Genet MD, Ben-Sahra I, Asara JM, et al. ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis. Genes Dev (2014) 28(17):1917-28. doi:10.1101/gad.245910.114
-
(2014)
Genes Dev
, vol.28
, Issue.17
, pp. 1917-1928
-
-
Liu, X.S.1
Haines, J.E.2
Mehanna, E.K.3
Genet, M.D.4
Ben-Sahra, I.5
Asara, J.M.6
|