The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication

Nature Communications

Volumn 6, Issue , 2015, Pages

  Macao, Bertil ^a   Uhler, Jay P ^a   Siibak, Triinu ^a   Zhu, Xuefeng ^a   Shi, Yonghong ^a   Sheng, Wenwen ^a   Olsson, Monica ^a   Stewart, James B ^b   Gustafsson, Claes M ^a   Falkenberg, Maria ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE GAMMA; EXONUCLEASE; DNA DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASE; MITOCHONDRIAL DNA; POLG PROTEIN, HUMAN; POLG PROTEIN, MOUSE;

ENZYME ACTIVITY; MITOCHONDRIAL DNA; MUTATION; PHENOTYPE; POLYMERIZATION; RODENT;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING; DNA REPLICATION; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; EXCISION REPAIR; FIBROBLAST; FOLLOW UP; GEL MOBILITY SHIFT ASSAY; GENE MUTATION; LIGATION; MITOCHONDRIAL DNA REPLICATION; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; ANIMAL; GENETICS; HUMAN; METABOLISM; POLYMERASE CHAIN REACTION; SF9 CELL LINE; SOUTHERN BLOTTING; SPODOPTERA;

MUS;

ANIMALS; BLOTTING, SOUTHERN; DNA REPLICATION; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASES; HUMANS; MICE; POLYMERASE CHAIN REACTION; SF9 CELLS; SPODOPTERA;

EID: 84935023031     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8303     Document Type: Article

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