Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin

Chemistry and Biology

Volumn 22, Issue 6, 2015, Pages 745-754

  Zhou, Yongjun ^a   Murphy, Annabel C ^a   Samborskyy, Markiyan ^a   Prediger, Patricia ^b   Dias, Luiz Carlos ^b   Leadlay, Peter F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CONGLOBATIN; DIMER; MONOMER; POLYKETIDE SYNTHASE; UNCLASSIFIED DRUG; OXAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG BINDING; DRUG MECHANISM; DRUG SYNTHESIS; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; STREPTOMYCES COELICOLOR; BACTERIAL GENE; CHEMISTRY; ESCHERICHIA COLI; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; METABOLISM; MULTIGENE FAMILY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STREPTOMYCES;

BACTERIA (MICROORGANISMS); STREPTOMYCES;

ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONING, MOLECULAR; ESCHERICHIA COLI; GENES, BACTERIAL; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MULTIGENE FAMILY; OXAZOLES; POLYKETIDE SYNTHASES; STREPTOMYCES;

EID: 84935021723     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2015.05.010     Document Type: Article

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