Covalent linkage mediates communication between ACP and TE domains in modular polyketide synthases

ChemBioChem

Volumn 9, Issue 6, 2008, Pages 905-915

  Tran, Lucky ^a   Tosin, Manuela ^a   Spencer, Jonathan B ^a   Leadlay, Peter F ^a   Weissman, Kira J ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

Acyl carrier proteins; Biosynthesis; Polyketides; Protein structures; Synthases; Thioesterases

Indexed keywords

ACYL CARRIER PROTEIN; POLYKETIDE SYNTHASE; THIOL ESTER HYDROLASE; BUTYRIC ACID DERIVATIVE;

ARTICLE; CONTROLLED STUDY; COVALENT BOND; ESCHERICHIA COLI; GENETIC ENGINEERING; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN PROTEIN INTERACTION; CALORIMETRY; CATALYSIS; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MASS SPECTROMETRY; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SURFACE PLASMON RESONANCE; TIME;

ACYL CARRIER PROTEIN; BUTYRATES; CALORIMETRY; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROLYSIS; MASS SPECTROMETRY; POLYKETIDE SYNTHASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SURFACE PLASMON RESONANCE; THIOLESTER HYDROLASES; TIME FACTORS;

EID: 44049097046     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200700738     Document Type: Article

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