메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

miR-193a-3p regulates the multi-drug resistance of bladder cancer by targeting the LOXL4 gene and the Oxidative Stress pathway

Author keywords

Bladder cancer; Chemoresistance; LOXL4; miR 193a 3p; Oxidative stress pathway

Indexed keywords

CISPLATIN; DOXORUBICIN; EPIRUBICIN; MICRORNA; MICRORNA 193A 3P; PACLITAXEL; PIRARUBICIN; UNCLASSIFIED DRUG; LOXL4 PROTEIN, HUMAN; MESSENGER RNA; MIRN193 MICRORNA, HUMAN; NUCLEAR PROTEIN; OXIDOREDUCTASE; RIBONUCLEOPROTEIN; SMALL INTERFERING RNA; SRSF2 PROTEIN, HUMAN;

EID: 84935016143     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-234     Document Type: Article
Times cited : (80)

References (52)
  • 2
    • 23044501890 scopus 로고    scopus 로고
    • Long-term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer
    • von der Maase H, Sengelov L, Roberts JT, Ricci S, Dogliotti L, Oliver T, Moore MJ, Zimmermann A, Arning M: Long-term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer. J Clin Oncol 1, 23:4602-4608. 10.1200/JCO.2005.07.757
    • (2005) J Clin Oncol , vol.23 , pp. 4602-4608
    • von der Maase, H.1    Sengelov, L.2    Roberts, J.T.3    Ricci, S.4    Dogliotti, L.5    Oliver, T.6    Moore, M.J.7    Zimmermann, A.8    Arning, M.9
  • 3
    • 84858226599 scopus 로고    scopus 로고
    • Progress in personalizing chemotherapy for bladder cancer
    • Chang JS, Lara PN, Pan C-X: Progress in personalizing chemotherapy for bladder cancer. Adv Urol 2012, 2012:364919.
    • (2012) Adv Urol , vol.2012 , pp. 364919
    • Chang, J.S.1    Lara, P.N.2    Pan, C.-X.3
  • 4
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel DP: MicroRNAs: target recognition and regulatory functions. Cell 1, 136:215-233. 10.1016/j.cell.2009.01.002
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 6
    • 84862182826 scopus 로고    scopus 로고
    • The duality of oncomiR addiction in the maintenance and treatment of cancer
    • Cheng CJ, Slack FJ: The duality of oncomiR addiction in the maintenance and treatment of cancer. Cancer J (Sudbury, Mass) 1, 18:232. 10.1097/PPO.0b013e318258b75b
    • (2012) Cancer J (Sudbury, Mass) , vol.18 , pp. 232
    • Cheng, C.J.1    Slack, F.J.2
  • 8
    • 84887101163 scopus 로고    scopus 로고
    • MicroRNAs and other non-coding RNAs as targets for anticancer drug development
    • Ling H, Fabbri M, Calin GA: MicroRNAs and other non-coding RNAs as targets for anticancer drug development. Nat Rev Drug Discov 1, 12:847-865. 10.1038/nrd4140
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 847-865
    • Ling, H.1    Fabbri, M.2    Calin, G.A.3
  • 9
    • 84880712727 scopus 로고    scopus 로고
    • Clinical advances in molecular biomarkers for cancer diagnosis and therapy
    • Sethi S, Ali S, Philip PA, Sarkar FH: Clinical advances in molecular biomarkers for cancer diagnosis and therapy. Int J Mol Sci 1, 14:14771-14784. 10.3390/ijms140714771
    • (2013) Int J Mol Sci , vol.14 , pp. 14771-14784
    • Sethi, S.1    Ali, S.2    Philip, P.A.3    Sarkar, F.H.4
  • 10
    • 84865471981 scopus 로고    scopus 로고
    • miRNAs as mediators of drug resistance
    • Haenisch S, Cascorbi I: miRNAs as mediators of drug resistance. Epigenomics 1, 4:369-381. 10.2217/epi.12.39
    • (2012) Epigenomics , vol.4 , pp. 369-381
    • Haenisch, S.1    Cascorbi, I.2
  • 11
    • 84884908851 scopus 로고    scopus 로고
    • miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer
    • Su S, Chang Y, Andreu-Vieyra C, Fang J, Yang Z, Han B, Lee A, Liang G: miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer. Oncogene 2013,32(39):4694-4701. 10.1038/onc.2012.483
    • (2013) Oncogene , vol.32 , Issue.39 , pp. 4694-4701
    • Su, S.1    Chang, Y.2    Andreu-Vieyra, C.3    Fang, J.4    Yang, Z.5    Han, B.6    Lee, A.7    Liang, G.8
  • 12
    • 42049104107 scopus 로고    scopus 로고
    • Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer
    • K-i K, Imoto I, Mogi S, Omura K, Inazawa J: Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. Cancer Res 1, 68:2094-2105. 10.1158/0008-5472.CAN-07-5194
    • (2008) Cancer Res , vol.68 , pp. 2094-2105
    • K-i, K.1    Imoto, I.2    Mogi, S.3    Omura, K.4    Inazawa, J.5
  • 14
    • 84877673227 scopus 로고    scopus 로고
    • Therapeutic potential of an anti-diabetic drug, metformin: alteration of miRNA expression in prostate cancer cells
    • Avci CB, Harman E, Dodurga Y, Susluer SY, Gunduz C: Therapeutic potential of an anti-diabetic drug, metformin: alteration of miRNA expression in prostate cancer cells. Asian Pac J Cancer Prev 1, 14:765-768. 10.7314/APJCP.2013.14.2.765
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 765-768
    • Avci, C.B.1    Harman, E.2    Dodurga, Y.3    Susluer, S.Y.4    Gunduz, C.5
  • 17
    • 84878630434 scopus 로고    scopus 로고
    • Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer
    • Yong FL, Law CW, Wang CW: Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer. BMC Cancer 1, 13:280. 10.1186/1471-2407-13-280
    • (2013) BMC Cancer , vol.13 , pp. 280
    • Yong, F.L.1    Law, C.W.2    Wang, C.W.3
  • 18
    • 79961171626 scopus 로고    scopus 로고
    • MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia
    • Gao X, Lin J, Li Y, Gao L, Wang X, Wang W, Kang H, Yan G, Wang L, Yu L: MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia. Oncogene 1, 30:3416-3428. 10.1038/onc.2011.62
    • (2011) Oncogene , vol.30 , pp. 3416-3428
    • Gao, X.1    Lin, J.2    Li, Y.3    Gao, L.4    Wang, X.5    Wang, W.6    Kang, H.7    Yan, G.8    Wang, L.9    Yu, L.10
  • 19
    • 84872454123 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t (8; 21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway
    • Li Y, Gao L, Luo X, Wang L, Gao X, Wang W, Sun J, Dou L, Li J, Xu C: Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t (8; 21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway. Blood 1, 121:499-509. 10.1182/blood-2012-07-444729
    • (2013) Blood , vol.121 , pp. 499-509
    • Li, Y.1    Gao, L.2    Luo, X.3    Wang, L.4    Gao, X.5    Wang, W.6    Sun, J.7    Dou, L.8    Li, J.9    Xu, C.10
  • 20
    • 79960970390 scopus 로고    scopus 로고
    • Inhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation
    • Iliopoulos D, Rotem A, Struhl K: Inhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation. Cancer Res 1, 71:5144-5153. 10.1158/0008-5472.CAN-11-0425
    • (2011) Cancer Res , vol.71 , pp. 5144-5153
    • Iliopoulos, D.1    Rotem, A.2    Struhl, K.3
  • 21
    • 79960069397 scopus 로고    scopus 로고
    • Impaired microRNA processing facilitates breast cancer cell invasion by upregulating urokinase-type plasminogen activator expression
    • Noh H, Hong S, Dong Z, Pan ZK, Jing Q, Huang S: Impaired microRNA processing facilitates breast cancer cell invasion by upregulating urokinase-type plasminogen activator expression. Genes Cancer 1, 2:140-150. 10.1177/1947601911408888
    • (2011) Genes Cancer , vol.2 , pp. 140-150
    • Noh, H.1    Hong, S.2    Dong, Z.3    Pan, Z.K.4    Jing, Q.5    Huang, S.6
  • 23
    • 84876524222 scopus 로고    scopus 로고
    • Gain-of-function microRNA screens identify miR-193a regulating proliferation and apoptosis in epithelial ovarian cancer cells
    • Nakano H, Yamada Y, Miyazawa T, Yoshida T: Gain-of-function microRNA screens identify miR-193a regulating proliferation and apoptosis in epithelial ovarian cancer cells. Int J Oncol 2013, 42:1875-1882.
    • (2013) Int J Oncol , vol.42 , pp. 1875-1882
    • Nakano, H.1    Yamada, Y.2    Miyazawa, T.3    Yoshida, T.4
  • 25
    • 84890540447 scopus 로고    scopus 로고
    • Demethylation of miR-9-3 and miR-193a genes suppresses proliferation and promotes apoptosis in non-small cell lung cancer cell lines
    • Wang J, Yang B, Han L, Li X, Tao H, Zhang S, Hu Y: Demethylation of miR-9-3 and miR-193a genes suppresses proliferation and promotes apoptosis in non-small cell lung cancer cell lines. Cell Physiol Biochem 1, 32:1707-1719. 10.1159/000356605
    • (2013) Cell Physiol Biochem , vol.32 , pp. 1707-1719
    • Wang, J.1    Yang, B.2    Han, L.3    Li, X.4    Tao, H.5    Zhang, S.6    Hu, Y.7
  • 26
    • 84878685848 scopus 로고    scopus 로고
    • Ionizing radiation-inducible microRNA miR-193a-3p induces apoptosis by directly targeting Mcl-1
    • Kwon JE, Kim BY, Kwak SY, Bae IH, Han YH: Ionizing radiation-inducible microRNA miR-193a-3p induces apoptosis by directly targeting Mcl-1. Apoptosis 1, 18:896-909. 10.1007/s10495-013-0841-7
    • (2013) Apoptosis , vol.18 , pp. 896-909
    • Kwon, J.E.1    Kim, B.Y.2    Kwak, S.Y.3    Bae, I.H.4    Han, Y.H.5
  • 27
    • 85027949778 scopus 로고    scopus 로고
    • MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway
    • Yu T, Li J, Yan M, Liu L, Lin H, Zhao F, Sun L, Zhang Y, Cui Y, Zhang F, Li J, He X, Yao M: MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway. Oncogene 2014. doi:10.1038/onc.2013.574
    • (2014) Oncogene
    • Yu, T.1    Li, J.2    Yan, M.3    Liu, L.4    Lin, H.5    Zhao, F.6    Sun, L.7    Zhang, Y.8    Cui, Y.9    Zhang, F.10    Li, J.11    He, X.12    Yao, M.13
  • 29
    • 84863142634 scopus 로고    scopus 로고
    • DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression
    • Ma K, He Y, Zhang H, Fei Q, Niu D, Wang D, Ding X, Xu H, Chen X, Zhu J: DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression. J Biol Chem 1, 287:5639-5649. 10.1074/jbc.M111.291229
    • (2012) J Biol Chem , vol.287 , pp. 5639-5649
    • Ma, K.1    He, Y.2    Zhang, H.3    Fei, Q.4    Niu, D.5    Wang, D.6    Ding, X.7    Xu, H.8    Chen, X.9    Zhu, J.10
  • 31
  • 32
    • 0242666198 scopus 로고    scopus 로고
    • Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD (P) H: quinone oxidoreductase-1 gene expression
    • Bloom DA, Jaiswal AK: Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf1, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD (P) H: quinone oxidoreductase-1 gene expression. J Biol Chem 2003, 278:44675-44682. 10.1074/jbc.M307633200
    • (2003) J Biol Chem , vol.278 , pp. 44675-44682
    • Bloom, D.A.1    Jaiswal, A.K.2
  • 33
    • 84870245054 scopus 로고    scopus 로고
    • Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo
    • Sarkar S, Dutta D, Samanta SK, Bhattacharya K, Pal BC, Li J, Datta K, Mandal C, Mandal C: Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo. Int J Cancer 1, 132:695-706. 10.1002/ijc.27687
    • (2013) Int J Cancer , vol.132 , pp. 695-706
    • Sarkar, S.1    Dutta, D.2    Samanta, S.K.3    Bhattacharya, K.4    Pal, B.C.5    Li, J.6    Datta, K.7    Mandal, C.8    Mandal, C.9
  • 35
    • 78650239327 scopus 로고    scopus 로고
    • LOXL4 as a selective molecular marker in primary and metastatic head/neck carcinoma
    • Scola N, Goeroegh T: LOXL4 as a selective molecular marker in primary and metastatic head/neck carcinoma. Anticancer Res 2010, 30:4567-4571.
    • (2010) Anticancer Res , vol.30 , pp. 4567-4571
    • Scola, N.1    Goeroegh, T.2
  • 37
    • 84872682606 scopus 로고    scopus 로고
    • Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer
    • Sebban S, Golan-Gerstl R, Karni R, Vaksman O, Davidson B, Reich R: Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer. Clin Exp Metastasis 1, 30:103-117. 10.1007/s10585-012-9514-0
    • (2013) Clin Exp Metastasis , vol.30 , pp. 103-117
    • Sebban, S.1    Golan-Gerstl, R.2    Karni, R.3    Vaksman, O.4    Davidson, B.5    Reich, R.6
  • 41
    • 70350356608 scopus 로고    scopus 로고
    • Differential expression of the LOX family genes in human colorectal adenocarcinomas
    • Kim Y, Roh S, Park J-Y, Kim Y, Cho DH, Kim JC: Differential expression of the LOX family genes in human colorectal adenocarcinomas. Oncol Rep 2009, 22:799-804.
    • (2009) Oncol Rep , vol.22 , pp. 799-804
    • Kim, Y.1    Roh, S.2    Park, J.-Y.3    Kim, Y.4    Cho, D.H.5    Kim, J.C.6
  • 42
    • 34249293694 scopus 로고    scopus 로고
    • LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer
    • Wu G, Guo Z, Chang X, Kim MS, Nagpal JK, Liu J, Maki JM, Kivirikko KI, Ethier SP, Trink B: LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer. Cancer Res 1, 67:4123-4129. 10.1158/0008-5472.CAN-07-0012
    • (2007) Cancer Res , vol.67 , pp. 4123-4129
    • Wu, G.1    Guo, Z.2    Chang, X.3    Kim, M.S.4    Nagpal, J.K.5    Liu, J.6    Maki, J.M.7    Kivirikko, K.I.8    Ethier, S.P.9    Trink, B.10
  • 43
    • 84885944468 scopus 로고    scopus 로고
    • The emerging role of the Nrf2-Keap1 signaling pathway in cancer
    • Jaramillo MC, Zhang DD: The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes Dev 1, 27:2179-2191. 10.1101/gad.225680.113
    • (2013) Genes Dev , vol.27 , pp. 2179-2191
    • Jaramillo, M.C.1    Zhang, D.D.2
  • 44
    • 84862323532 scopus 로고    scopus 로고
    • Towards Alzheimer's root cause: ECSIT as an integrating hub between oxidative stress, inflammation and mitochondrial dysfunction
    • Soler-López M, Badiola N, Zanzoni A, Aloy P: Towards Alzheimer's root cause: ECSIT as an integrating hub between oxidative stress, inflammation and mitochondrial dysfunction. Bioessays 1, 34:532-541. 10.1002/bies.201100193
    • (2012) Bioessays , vol.34 , pp. 532-541
    • Soler-López, M.1    Badiola, N.2    Zanzoni, A.3    Aloy, P.4
  • 48
    • 0347125328 scopus 로고    scopus 로고
    • JASPAR: an open-access database for eukaryotic transcription factor binding profiles
    • Sandelin A, Alkema W, Engström P, Wasserman WW, Lenhard B: JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res 1, 32:D91-D94. 10.1093/nar/gkh012
    • (2004) Nucleic Acids Res , vol.32 , pp. D91-D94
    • Sandelin, A.1    Alkema, W.2    Engström, P.3    Wasserman, W.W.4    Lenhard, B.5
  • 50
    • 84866134107 scopus 로고    scopus 로고
    • Exploration of the correlations between interferon-gamma in patient serum and HEPACAM in bladder transitional cell carcinoma, and the interferon-gamma mechanism Inhibiting BIU-87 proliferation
    • Xu B, He Y, Wu X, Luo C, Liu A, Zhang J: Exploration of the correlations between interferon-gamma in patient serum and HEPACAM in bladder transitional cell carcinoma, and the interferon-gamma mechanism Inhibiting BIU-87 proliferation. J Urol 1, 188:1346-1353. 10.1016/j.juro.2012.06.005
    • (2012) J Urol , vol.188 , pp. 1346-1353
    • Xu, B.1    He, Y.2    Wu, X.3    Luo, C.4    Liu, A.5    Zhang, J.6
  • 51
    • 0035810343 scopus 로고    scopus 로고
    • Determination of inhibitors' potency (IC50) by a direct high-performance liquid chromatographic method on an immobilised acetylcholinesterase column
    • Andrisano V, Bartolini M, Gotti R, Cavrini V, Felix G: Determination of inhibitors' potency (IC50) by a direct high-performance liquid chromatographic method on an immobilised acetylcholinesterase column. J Chromatogr B Biomed Sci Appl 1, 753:375-383. 10.1016/S0378-4347(00)00571-5
    • (2001) J Chromatogr B Biomed Sci Appl , vol.753 , pp. 375-383
    • Andrisano, V.1    Bartolini, M.2    Gotti, R.3    Cavrini, V.4    Felix, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.