Demethylation of miR-9-3 and miR-193a genes suppresses proliferation and promotes apoptosis in non-small cell lung cancer cell lines

Cellular Physiology and Biochemistry

Volumn 32, Issue 6, 2013, Pages 1707-1719

  Wang, Jinliang ^a   Yang, Bo ^a   Han, Lu ^a   Li, Xiaoyan ^a   Tao, Haitao ^a   Zhang, Sujie ^a   Hu, Yi ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Apoptosis; Cancer; Demethylation; Gene expression; Methylation; miR 193a; miR 9 3; Non small cell lung carcinomas (NSCLCs); Proliferation; Signaling pathway

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CASPASE 3; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA 193A; MICRORNA 9 3; PROTEIN MCL 1; UNCLASSIFIED DRUG; MESSENGER RNA; MICRORNA 9;

APOPTOSIS; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; DEMETHYLATION; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA METHYLATION; UPREGULATION; WESTERN BLOTTING; CANCER GROWTH; CANCER INHIBITION; CARCINOGENESIS; CELL POPULATION; CELL SURVIVAL; DNA METHYLATION; EPIGENETICS; FLOW CYTOMETRY; LUNG CANCER CELL LINE; MTT ASSAY; NON SMALL CELL LUNG CANCER;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; AZACITIDINE; BASE SEQUENCE; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; DNA METHYLATION; DOWN-REGULATION; DOXORUBICIN; HUMANS; LUNG NEOPLASMS; MICRORNAS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; NF-KAPPA B; OLIGONUCLEOTIDES, ANTISENSE; PROMOTER REGIONS, GENETIC; SEQUENCE ALIGNMENT; UP-REGULATION;

EID: 84890540447     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000356605     Document Type: Article

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