Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight

Journal of Controlled Release

Volumn 211, Issue 1, 2015, Pages 1-9

  Ragelle, Héloïse ^a,c   Colombo, Stefano ^b   Pourcelle, Vincent ^a   Vanvarenberg, Kevin ^a   Vandermeulen, Gaëlle ^a   Bouzin, Caroline ^a   Marchand Brynaert, Jacqueline ^a   Feron, Olivier ^a   Foged, Camilla ^b   Préat, Véronique ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Chitosan; Nanoparticles; RGD peptidomimetic; siRNA; Stem loop RT qPCR; v 3 Integrin

Indexed keywords

AMINO ACIDS; CARRIER CONCENTRATION; CELL CULTURE; CELLS; CHITIN; CHITOSAN; CYTOLOGY; ETHYLENE; GENE THERAPY; GENES; LIGANDS; NITROGEN COMPOUNDS; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYMERASE CHAIN REACTION; PROTEINS; RNA; TRANSCRIPTION; TUMORS;

ENHANCED GREEN FLUORESCENT PROTEIN; INTEGRINS; NON-SMALL CELL LUNG CARCINOMATA; PEPTIDOMIMETICS; QUANTITATIVE POLYMERASE CHAIN REACTION; SIRNA; SMALL INTERFERING RNA (SIRNA); STEM-LOOP;

NANOPARTICLES;

ARGININE; ASPARTIC ACID; CHITOSAN; ENHANCED GREEN FLUORESCENT PROTEIN; GLYCINE; NANOCARRIER; PEPTIDOMIMETIC AGENT; POLYETHYLENEIMINE; SMALL INTERFERING RNA; VITRONECTIN RECEPTOR; GREEN FLUORESCENT PROTEIN; IMINE; INTEGRIN; MACROGOL DERIVATIVE; NANOPARTICLE; POLY(ETHYLENE IMINE); POLYETHYLENE DERIVATIVE;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; ENDOSOME; GENE SILENCING; HUMAN; HUMAN CELL; LUNG CANCER CELL LINE; LYSOSOME; NON SMALL CELL LUNG CANCER; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; BIOSYNTHESIS; DRUG EFFECTS; GENE TRANSFER; GENETICS; INTRACELLULAR FLUID; METABOLISM; TUMOR CELL LINE;

CELL LINE, TUMOR; CHITOSAN; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; HUMANS; IMINES; INTEGRINS; INTRACELLULAR FLUID; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYETHYLENES; RNA, SMALL INTERFERING;

EID: 84935015379     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.05.274     Document Type: Article

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