메뉴 건너뛰기




Volumn 244, Issue 1, 2011, Pages 19-44

Chitosan and chitosan derivatives in drug delivery and tissue engineering

Author keywords

Chitosan; Chitosan derivatives; Drug delivery

Indexed keywords


EID: 80053525040     PISSN: 00653195     EISSN: None     Source Type: Book Series    
DOI: 10.1007/12_2011_137     Document Type: Review
Times cited : (310)

References (148)
  • 1
    • 75149147998 scopus 로고    scopus 로고
    • Targeted delivery of low molecular drugs using chitosan and its derivatives
    • Park JH, Saravanakumar G et al (2010) Targeted delivery of low molecular drugs using chitosan and its derivatives. Adv Drug Deliv Rev 62:28-41
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 28-41
    • Park, J.H.1    Saravanakumar, G.2
  • 2
    • 33747846583 scopus 로고    scopus 로고
    • Chitin and chitosan: Properties and applications
    • DOI 10.1016/j.progpolymsci.2006.06.001, PII S0079670006000530
    • Rinaudo M (2006) Chitin and chitosan: properties and applications. Prog Polym Sci 31:603-632 (Pubitemid 44287019)
    • (2006) Progress in Polymer Science (Oxford) , vol.31 , Issue.7 , pp. 603-632
    • Rinaudo, M.1
  • 3
    • 69749100783 scopus 로고    scopus 로고
    • An investigation on the short-term biodegradability of chitosan with various molecular weights and degrees of deacetylation
    • Bagheri-Khoulenjani S, Taghizadeh SM et al (2009) An investigation on the short-term biodegradability of chitosan with various molecular weights and degrees of deacetylation. Carbohydr Polym 78:773-778
    • (2009) Carbohydr Polym , vol.78 , pp. 773-778
    • Bagheri-Khoulenjani, S.1    Taghizadeh, S.M.2
  • 4
    • 0038670289 scopus 로고    scopus 로고
    • In vitro degradation rates of partially N-acetylated chitosans in human serum
    • DOI 10.1016/S0008-6215(96)00332-1, PII S0008621596003321
    • Varum KM, Myhr MM et al (1997) In vitro degradation rates of partially N-acetylated chitosans in human serum. Carbohydr Res 299:99-101 (Pubitemid 27138460)
    • (1997) Carbohydrate Research , vol.299 , Issue.1-2 , pp. 99-101
    • Varum, K.M.1    Myhr, M.M.2    Hjerde, R.J.N.3    Smidsrod, O.4
  • 6
    • 4444246205 scopus 로고    scopus 로고
    • Chemically modified chitin and chitosan as biomaterials
    • Sashiwa H, Aiba SI (2004) Chemically modified chitin and chitosan as biomaterials. Prog Polym Sci 29:887-908
    • (2004) Prog Polym Sci , vol.29 , pp. 887-908
    • Sashiwa, H.1    Aiba, S.I.2
  • 7
    • 0027269129 scopus 로고
    • Production of chitosan by funghi
    • Rane KD, Hoover DG (1993) Production of chitosan by funghi. Food Biotechnol 7:11-33
    • (1993) Food Biotechnol , vol.7 , pp. 11-33
    • Rane, K.D.1    Hoover, D.G.2
  • 8
    • 77949402052 scopus 로고    scopus 로고
    • Chitosan amphiphilic derivatives. Chemistry and applications
    • Aranaz I, Harris R et al (2010) Chitosan amphiphilic derivatives. Chemistry and applications. Curr Org Chem 14:308-330
    • (2010) Curr Org Chem , vol.14 , pp. 308-330
    • Aranaz, I.1    Harris, R.2
  • 9
    • 0031783879 scopus 로고    scopus 로고
    • Chitosan and its use as a pharmaceutical excipient
    • DOI 10.1023/A:1011929016601
    • Illum L (1998) Chitosan and its use as a pharmaceutical excipient. Pharm Res 15:1326-1331 (Pubitemid 28427917)
    • (1998) Pharmaceutical Research , vol.15 , Issue.9 , pp. 1326-1331
    • Illum, L.1
  • 11
    • 57349172741 scopus 로고    scopus 로고
    • New drug delivery systems based on chitosan
    • Paños I, Acosta N et al (2008) New drug delivery systems based on chitosan. Curr Drug Discov Technol 5:333-341
    • (2008) Curr Drug Discov Technol , vol.5 , pp. 333-341
    • Paños, I.1    Acosta, N.2
  • 12
    • 34248637901 scopus 로고    scopus 로고
    • The promise of chitosan microspheres in drug delivery systems
    • DOI 10.1517/17425247.4.3.263
    • Varshosaz J (2007) The promise of chitosan microspheres in drug delivery systems. Expert Opin Drug Deliv 4:263-273 (Pubitemid 46767627)
    • (2007) Expert Opinion on Drug Delivery , vol.4 , Issue.3 , pp. 263-273
    • Varshosaz, J.1
  • 13
    • 0033151411 scopus 로고    scopus 로고
    • Porous chitosan scaffolds for tissue engineering
    • DOI 10.1016/S0142-9612(99)00011-3, PII S0142961298000113
    • Madihally SV, Matthew HWT (1999) Porous chitosan scaffolds for tissue engineering. Biomaterials 20:1133-1142 (Pubitemid 29233382)
    • (1999) Biomaterials , vol.20 , Issue.12 , pp. 1133-1142
    • Madihally, S.V.1    Matthew, H.W.T.2
  • 14
    • 0026800237 scopus 로고
    • In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers
    • Lehr C-M, Bouwstra JA et al (1992) In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int J Pharm 78:43-48
    • (1992) Int J Pharm , vol.78 , pp. 43-48
    • Lehr, C.-M.1    Bouwstra, J.A.2
  • 15
    • 37549024638 scopus 로고    scopus 로고
    • Effect of chitosan molecular weight and deacetylation degree on hemostasis
    • Yang J, Tian F et al (2008) Effect of chitosan molecular weight and deacetylation degree on hemostasis. J Biomed Mater Res B Appl Biomater 84B:131-137
    • (2008) J Biomed Mater Res B Appl Biomater , vol.84 B , pp. 131-137
    • Yang, J.1    Tian, F.2
  • 16
    • 33846202184 scopus 로고    scopus 로고
    • Effects of molecular weight and deacetylation degree of chitin/chitosan on wound healing
    • DOI 10.1016/j.carbpol.2006.07.007, PII S0144861706003341
    • Minagawa T, Okamura Y et al (2007) Effects of molecular weight and deacetylation degree of chitin/chitosan on wound healing. Carbohydr Polym 67:640-644 (Pubitemid 46097095)
    • (2007) Carbohydrate Polymers , vol.67 , Issue.4 , pp. 640-644
    • Minagawa, T.1    Okamura, Y.2    Shigemasa, Y.3    Minami, S.4    Okamoto, Y.5
  • 18
    • 50349090460 scopus 로고    scopus 로고
    • Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties
    • Ong SY, Wu J et al (2008) Development of a chitosan-based wound dressing with improved hemostatic and antimicrobial properties. Biomaterials 29:4323-4332
    • (2008) Biomaterials , vol.29 , pp. 4323-4332
    • Ong, S.Y.1    Wu, J.2
  • 20
    • 34248227817 scopus 로고    scopus 로고
    • Chitosan and its derivatives for gene delivery
    • Lee KY (2007) Chitosan and its derivatives for gene delivery. Macromol Res 15:195-201
    • (2007) Macromol Res , vol.15 , pp. 195-201
    • Lee, K.Y.1
  • 22
    • 0031722107 scopus 로고    scopus 로고
    • Chitosan-based vector/DNA complexes for gene delivery: Biophysical characteristics and transfection ability
    • DOI 10.1023/A:1011981000671
    • Erbacher P, Zou SM et al (1998) Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability. Pharm Res 15:1332-1339 (Pubitemid 28427918)
    • (1998) Pharmaceutical Research , vol.15 , Issue.9 , pp. 1332-1339
    • Erbacher, P.1    Zou, S.2    Bettinger, T.3    Steffan, A.-M.4    Remy, J.-S.5
  • 23
    • 43049175030 scopus 로고    scopus 로고
    • Chitosan-modifications and applications: Opportunities galore
    • Mourya VK, Inamdar NN (2008) Chitosan-modifications and applications: opportunities galore. React Funct Polym 68:1013-1051
    • (2008) React Funct Polym , vol.68 , pp. 1013-1051
    • Mourya, V.K.1    Inamdar, N.N.2
  • 24
    • 28544437497 scopus 로고    scopus 로고
    • Enzymatic production and biological activities of chitosan oligosaccharides (COS): A review
    • DOI 10.1016/j.carbpol.2005.08.012, PII S0144861705003449
    • Kim S-K, Rajapakse N (2005) Enzymatic production and biological activities of chitosan oligosaccharides (COS): a review. Carbohydr Polym 62:357-368 (Pubitemid 41745217)
    • (2005) Carbohydrate Polymers , vol.62 , Issue.4 , pp. 357-368
    • Kim, S.-K.1    Rajapakse, N.2
  • 25
    • 34047253783 scopus 로고    scopus 로고
    • Kinetics of hydrolysis of chitin/chitosan oligomers in concentrated hydrochloric acid
    • DOI 10.1016/j.carres.2007.02.022, PII S0008621507001097
    • Einbu A, Grasdalen H et al (2007) Kinetics of hydrolysis of chitin/chitosan oligomers in concentrated hydrochloric acid. Carbohydr Res 342:1055-1062 (Pubitemid 46551994)
    • (2007) Carbohydrate Research , vol.342 , Issue.8 , pp. 1055-1062
    • Einbu, A.1    Grasdalen, H.2    Varum, K.M.3
  • 26
    • 75149147526 scopus 로고    scopus 로고
    • Biodegradation, biodistribution and toxicity of chitosan
    • Kean T, ThanouM(2010) Biodegradation, biodistribution and toxicity of chitosan. Adv Drug Deliv Rev 62:3-11
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 3-11
    • Kean, T.1    Thanou, M.2
  • 27
    • 36448934180 scopus 로고    scopus 로고
    • The controlling biodegradation of chitosan fibers by N-acetylation in vitro and in vivo
    • DOI 10.1007/s10856-007-3013-x, Special Issue: Selected Papers from the 1st Chinese-European Symposium on Biomaterials in Regenerative Medicine, Suzhou, China, April 2006. Guest Editors: Xingdong Zhang and C. James Kirkpatrick
    • Yang YM, Hu W et al (2007) The controlling biodegradation of chitosan fibers by N-acetylation in vitro and in vivo. J Mater Sci Mater Med 18:2117-2121 (Pubitemid 350167374)
    • (2007) Journal of Materials Science: Materials in Medicine , vol.18 , Issue.11 , pp. 2117-2121
    • Yang, Y.M.1    Hu, W.2    Wang, X.D.3    Gu, X.S.4
  • 28
    • 0033960143 scopus 로고    scopus 로고
    • Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers
    • DOI 10.1016/S0168-3659(99)00131-5, PII S0168365999001315
    • Thanou MM, Kotze AF et al (2000) Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal Caco-2 cell monolayers. J Control Release 64:15-25 (Pubitemid 30035304)
    • (2000) Journal of Controlled Release , vol.64 , Issue.1-3 , pp. 15-25
    • Thanou, M.M.1    Kotze, A.F.2    Scharringhausen, T.3    Luessen, H.L.4    De Boer, A.G.5    Verhoef, J.C.6    Junginger, H.E.7
  • 30
    • 46749090384 scopus 로고    scopus 로고
    • Synthesis, characterization and in vitro biological properties of O-methyl free N, N, N-trimethylated chitosan
    • Verheul RJ, Amidi M et al (2008) Synthesis, characterization and in vitro biological properties of O-methyl free N, N, N-trimethylated chitosan. Biomaterials 29:3642-3649
    • (2008) Biomaterials , vol.29 , pp. 3642-3649
    • Verheul, R.J.1    Amidi, M.2
  • 31
    • 0034955331 scopus 로고    scopus 로고
    • Water-soluble and low molecular weight chitosan-based plasmid DNA delivery
    • DOI 10.1023/A:1011037807261
    • Lee M, Nah JW et al (2001) Water-soluble and low molecular weight chitosan-based plasmid DNA delivery. Pharm Res 18:427-431 (Pubitemid 32592572)
    • (2001) Pharmaceutical Research , vol.18 , Issue.4 , pp. 427-431
    • Lee, M.1    Nah, J.-W.2    Kwon, Y.3    Koh, J.J.4    Ko, K.S.5    Kim, S.W.6
  • 32
    • 0034786764 scopus 로고    scopus 로고
    • Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo
    • DOI 10.1038/sj.gt.3301492
    • Koping-Hoggard M, Tubulekas I et al (2001) Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo. Gene Ther 8:1108-1121 (Pubitemid 32962708)
    • (2001) Gene Therapy , vol.8 , Issue.14 , pp. 1108-1121
    • Koping-Hoggard, M.1    Tubulekas, I.2    Guan, H.3    Edwards, K.4    Nilsson, M.5    Varum, K.M.6    Artursson, P.7
  • 34
    • 16344377289 scopus 로고    scopus 로고
    • Trimethylated chitosans as non-viral gene delivery vectors: Cytotoxicity and transfection efficiency
    • DOI 10.1016/j.jconrel.2005.01.001
    • Kean T, Roth S et al (2005) Trimethylated chitosans as non-viral gene delivery vectors: cytotoxicity and transfection efficiency. J Control Release 103:643-653 (Pubitemid 40471022)
    • (2005) Journal of Controlled Release , vol.103 , Issue.3 , pp. 643-653
    • Kean, T.1    Roth, S.2    Thanou, M.3
  • 35
    • 77955588647 scopus 로고    scopus 로고
    • Tailorable thiolated trimethyl chitosans for covalently stabilized nanoparticles
    • Verheul RJ, van der Wal S et al (2010) Tailorable thiolated trimethyl chitosans for covalently stabilized nanoparticles. Biomacromolecules 11:1965-1971
    • (2010) Biomacromolecules , vol.11 , pp. 1965-1971
    • Verheul, R.J.1    Van Der Wal, S.2
  • 36
    • 78650392120 scopus 로고    scopus 로고
    • Gene silencing activity of siRNA polyplexes based on thiolated N, N, N-trimethylated chitosan
    • Varkouhi AK, Verheul RJ et al (2010) Gene silencing activity of siRNA polyplexes based on thiolated N, N, N-trimethylated chitosan. Bioconjug Chem 21:2339-2346
    • (2010) Bioconjug Chem , vol.21 , pp. 2339-2346
    • Varkouhi, A.K.1    Verheul, R.J.2
  • 37
    • 68549122512 scopus 로고    scopus 로고
    • Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery
    • Yin LC, Ding JY et al (2009) Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery. Biomaterials 30:5691-5700
    • (2009) Biomaterials , vol.30 , pp. 5691-5700
    • Yin, L.C.1    Ding, J.Y.2
  • 38
    • 33644887463 scopus 로고    scopus 로고
    • Thiolated chitosans: Design and in vivo evaluation of a mucoadhesive buccal peptide drug delivery system
    • Langoth N, Kahlbacher H et al (2006) Thiolated chitosans: design and in vivo evaluation of a mucoadhesive buccal peptide drug delivery system. Pharm Res 23:573-579
    • (2006) Pharm Res , vol.23 , pp. 573-579
    • Langoth, N.1    Kahlbacher, H.2
  • 39
    • 79952740979 scopus 로고    scopus 로고
    • Succinated chitosan as a gene carrier for improved chitosan solubility and gene transfection
    • Toh EK-W, Chen H-Y et al (2011) Succinated chitosan as a gene carrier for improved chitosan solubility and gene transfection. Nanomedicine 7(2):174-183
    • (2011) Nanomedicine , vol.7 , Issue.2 , pp. 174-183
    • Ek-W, T.1    Chen, H.-Y.2
  • 40
    • 67349091776 scopus 로고    scopus 로고
    • Mannosylated chitosan-graft-polyethylenimine as a gene carrier for Raw 264.7 cell targeting
    • Jiang H-L, Kim Y-K et al (2009) Mannosylated chitosan-graft- polyethylenimine as a gene carrier for Raw 264.7 cell targeting. Int J Pharm 375:133-139
    • (2009) Int J Pharm , vol.375 , pp. 133-139
    • Jiang, H.-L.1    Kim, Y.-K.2
  • 42
    • 75149147065 scopus 로고    scopus 로고
    • Chitosan-graft-polyethylenimine with improved properties as a potential gene vector
    • Li Z-T, Guo J et al (2010) Chitosan-graft-polyethylenimine with improved properties as a potential gene vector. Carbohydr Polym 80:254-259
    • (2010) Carbohydr Polym , vol.80 , pp. 254-259
    • Li, Z.-T.1    Guo, J.2
  • 43
    • 67650608146 scopus 로고    scopus 로고
    • Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells
    • Jere D, Jiang H-L et al (2009) Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells. Int J Pharm 378:194-200
    • (2009) Int J Pharm , vol.378 , pp. 194-200
    • Jere, D.1    Jiang, H.-L.2
  • 44
    • 77649191250 scopus 로고    scopus 로고
    • Gene-carried chitosan-linked-PEI induced high gene transfection efficiency with low toxicity and significant tumor-suppressive activity
    • Gao J-Q, Zhao Q-Q et al (2010) Gene-carried chitosan-linked-PEI induced high gene transfection efficiency with low toxicity and significant tumor-suppressive activity. Int J Pharm 387:286-294
    • (2010) Int J Pharm , vol.387 , pp. 286-294
    • Gao, J.-Q.1    Zhao, Q.-Q.2
  • 45
    • 77953960004 scopus 로고    scopus 로고
    • Pegylated poly-l-arginine derivatives of chitosan for effective delivery of siRNA
    • Noh SM, Park MO et al (2010) Pegylated poly-l-arginine derivatives of chitosan for effective delivery of siRNA. J Control Release 145:159-164
    • (2010) J Control Release , vol.145 , pp. 159-164
    • Noh, S.M.1    Park, M.O.2
  • 46
    • 44249111011 scopus 로고    scopus 로고
    • Enhancing polysaccharide-mediated delivery of nucleic acids through functionalization with secondary and tertiary amines
    • DOI 10.2174/156802608783790947
    • Ghosn B, Kasturi SP et al (2008) Enhancing polysaccharide-mediated delivery of nucleic acids through functionalization with secondary and tertiary amines. Curr Top Med Chem 8:331-340 (Pubitemid 351791027)
    • (2008) Current Topics in Medicinal Chemistry , vol.8 , Issue.4 , pp. 331-340
    • Ghosn, B.1    Kasturi, S.P.2    Roy, K.3
  • 48
    • 77953728674 scopus 로고    scopus 로고
    • Synthesis and characterization of low-toxic amphiphilic chitosan derivatives and their application as micelle carrier for antitumor drug
    • Huo M, Zhang Y et al (2010) Synthesis and characterization of low-toxic amphiphilic chitosan derivatives and their application as micelle carrier for antitumor drug. Int J Pharm 394:162-173
    • (2010) Int J Pharm , vol.394 , pp. 162-173
    • Huo, M.1    Zhang, Y.2
  • 49
    • 33847032439 scopus 로고    scopus 로고
    • Polymeric micelle systems of hydroxycamptothecin based on amphiphilic N-alkyl-N-trimethyl chitosan derivatives
    • DOI 10.1016/j.colsurfb.2006.11.031, PII S0927776506004000
    • Zhang C, Ding Y et al (2007) Polymeric micelle systems of hydroxycamptothecin based on amphiphilic N-alkyl-N-trimethyl chitosan derivatives. Colloids Surf B 55:192-199 (Pubitemid 46274240)
    • (2007) Colloids and Surfaces B: Biointerfaces , vol.55 , Issue.2 , pp. 192-199
    • Zhang, C.1    Ding, Y.2    Yu, L.3    Ping, Q.4
  • 51
    • 25844475878 scopus 로고    scopus 로고
    • Specific interactions in modified chitosan systems
    • DOI 10.1021/bm0580025
    • Rinaudo M, Auzely R et al (2005) Specific interactions in modified chitosan systems. Biomacromolecules 6:2396-2407 (Pubitemid 41388249)
    • (2005) Biomacromolecules , vol.6 , Issue.5 , pp. 2396-2407
    • Rinaudo, M.1    Auzely, R.2    Vallin, C.3    Mullagaliev, I.4
  • 52
    • 46549086982 scopus 로고    scopus 로고
    • The aggregative behavior of hydrophobically modified chitosans with high substitution degree in aqueous solution
    • Ortona O, D'Errico G et al (2008) The aggregative behavior of hydrophobically modified chitosans with high substitution degree in aqueous solution. Carbohydr Polym 74:16-22
    • (2008) Carbohydr Polym , vol.74 , pp. 16-22
    • Ortona, O.1    D'Errico, G.2
  • 53
    • 8144225129 scopus 로고    scopus 로고
    • Self-assembly and characterization of paclitaxel-loaded N-octyl-O-sulfate chitosan micellar system
    • DOI 10.1016/j.colsurfb.2004.09.002, PII S0927776504002772
    • Zhang C, Qineng P et al (2004) Self-assembly and characterization of paclitaxel-loaded N-octyl-O-sulfate chitosan micellar system. Colloids Surf B 39:69-75 (Pubitemid 39473356)
    • (2004) Colloids and Surfaces B: Biointerfaces , vol.39 , Issue.1-2 , pp. 69-75
    • Zhang, C.1    Qineng, P.2    Zhang, H.3
  • 54
    • 0041860927 scopus 로고    scopus 로고
    • Preparation of N-alkyl-O-sulfate chitosan derivatives and micellar solubilization of taxol
    • Zhang C, Ping Q et al (2003) Preparation of N-alkyl-O-sulfate chitosan derivatives and micellar solubilization of taxol. Carbohydr Polym 54:137-141
    • (2003) Carbohydr Polym , vol.54 , pp. 137-141
    • Zhang, C.1    Ping, Q.2
  • 55
    • 33947172648 scopus 로고    scopus 로고
    • A series of novel chitosan derivatives: Synthesis, characterization and micellar solubilization of paclitaxel
    • DOI 10.1016/j.carbpol.2006.08.023, PII S0144861706004140
    • Yao Z, Zhang C et al (2007) A series of novel chitosan derivatives: synthesis, characterization and micellar solubilization of paclitaxel. Carbohydr Polym 68:781-792 (Pubitemid 46412476)
    • (2007) Carbohydrate Polymers , vol.68 , Issue.4 , pp. 781-792
    • Yao, Z.1    Zhang, C.2    Ping, Q.3    Yu, L.4
  • 56
    • 62649086512 scopus 로고    scopus 로고
    • PEG conjugated N-octyl-O-sulfate chitosan micelles for delivery of paclitaxel: In vitro characterization and in vivo evaluation
    • Qu G, Yao Z et al (2009) PEG conjugated N-octyl-O-sulfate chitosan micelles for delivery of paclitaxel: in vitro characterization and in vivo evaluation. Eur J Pharm Sci 37:98-105
    • (2009) Eur J Pharm Sci , vol.37 , pp. 98-105
    • Qu, G.1    Yao, Z.2
  • 57
    • 33847058001 scopus 로고    scopus 로고
    • Preparation and characterization of N-succinyl-N′-octyl chitosan micelles as doxorubicin carriers for effective anti-tumor activity
    • DOI 10.1016/j.colsurfb.2006.12.006, PII S0927776506004176
    • Xiangyang X, Ling L et al (2007) Preparation and characterization of N-succinyl-N'-octyl chitosan micelles as doxorubicin carriers for effective anti-tumor activity. Colloids Surf B 55:222-228 (Pubitemid 46274249)
    • (2007) Colloids and Surfaces B: Biointerfaces , vol.55 , Issue.2 , pp. 222-228
    • Xiangyang, X.1    Ling, L.2    Jianping, Z.3    Shiyue, L.4    Jie, Y.5    Xiaojin, Y.6    Jinsheng, R.7
  • 58
    • 60349086689 scopus 로고    scopus 로고
    • Synthesis of novel pH-sensitive chitosan graft copolymers and micellar solubilization of paclitaxel
    • Li H, Liu J et al (2009) Synthesis of novel pH-sensitive chitosan graft copolymers and micellar solubilization of paclitaxel. Int J Biol Macromol 44:249-256
    • (2009) Int J Biol Macromol , vol.44 , pp. 249-256
    • Li, H.1    Liu, J.2
  • 59
    • 77955416813 scopus 로고    scopus 로고
    • Novel pH-sensitive chitosan-derived micelles loaded with paclitaxel
    • Liu J, Li H et al (2010) Novel pH-sensitive chitosan-derived micelles loaded with paclitaxel. Carbohydr Polym 82:432-439
    • (2010) Carbohydr Polym , vol.82 , pp. 432-439
    • Liu, J.1    Li, H.2
  • 60
    • 77956475151 scopus 로고    scopus 로고
    • Novel amphiphilic chitosan derivatives: Synthesis, characterization and micellar solubilization of rotenone
    • Lao S-B, Zhang Z-X et al (2010) Novel amphiphilic chitosan derivatives: synthesis, characterization and micellar solubilization of rotenone. Carbohydr Polym 82:1136-1142
    • (2010) Carbohydr Polym , vol.82 , pp. 1136-1142
    • Lao, S.-B.1    Zhang, Z.-X.2
  • 61
    • 77953916580 scopus 로고    scopus 로고
    • Synthesis of cross-linked N-(2-carboxybenzyl) chitosan pH sensitive polyelectrolyte and its use for drug controlled delivery
    • Koutroumanis KP, Avgoustakis K et al (2010) Synthesis of cross-linked N-(2-carboxybenzyl) chitosan pH sensitive polyelectrolyte and its use for drug controlled delivery. Carbohydr Polym 82:181-188
    • (2010) Carbohydr Polym , vol.82 , pp. 181-188
    • Koutroumanis, K.P.1    Avgoustakis, K.2
  • 64
    • 33750445973 scopus 로고    scopus 로고
    • Preparation of polymeric micelles based on chitosan bearing a small amount of highly hydrophobic groups
    • DOI 10.1016/j.carbpol.2006.04.008, PII S0144861706002074
    • Jiang G-B, Quan D et al (2006) Preparation of polymeric micelles based on chitosan bearing a small amount of highly hydrophobic groups. Carbohydr Polym 66:514-520 (Pubitemid 44648321)
    • (2006) Carbohydrate Polymers , vol.66 , Issue.4 , pp. 514-520
    • Jiang, G.-B.1    Quan, D.2    Liao, K.3    Wang, H.4
  • 65
    • 77952888302 scopus 로고    scopus 로고
    • Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: Factors affecting the complexation
    • Du Y-Z, Lu P et al (2010) Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: factors affecting the complexation. Int J Pharm 391:260-266
    • (2010) Int J Pharm , vol.391 , pp. 260-266
    • Du, Y.-Z.1    Lu, P.2
  • 66
    • 78650250435 scopus 로고    scopus 로고
    • Linoleic acid-grafted chitosan oligosaccharide micelles for intracellular drug delivery and reverse drug resistance of tumor cells
    • Du Y-Z, Wang L et al (2011) Linoleic acid-grafted chitosan oligosaccharide micelles for intracellular drug delivery and reverse drug resistance of tumor cells. Int J Biol Macromol 48(1):215-222
    • (2011) Int J Biol Macromol , vol.48 , Issue.1 , pp. 215-222
    • Du, Y.-Z.1    Wang, L.2
  • 67
    • 60449087425 scopus 로고    scopus 로고
    • Preparation and characteristics of linoleic acid-grafted chitosan oligosaccharide micelles as a carrier for doxorubicin
    • Du Y-Z, Wang L et al (2009) Preparation and characteristics of linoleic acid-grafted chitosan oligosaccharide micelles as a carrier for doxorubicin. Colloids Surf B 69:257-263
    • (2009) Colloids Surf B , vol.69 , pp. 257-263
    • Du, Y.-Z.1    Wang, L.2
  • 68
    • 39549108475 scopus 로고    scopus 로고
    • Core-modified chitosan-based polymeric micelles for controlled release of doxorubicin
    • Ye Y-Q, Yang F-L et al (2008) Core-modified chitosan-based polymeric micelles for controlled release of doxorubicin. Int J Pharm 352:294-301
    • (2008) Int J Pharm , vol.352 , pp. 294-301
    • Ye, Y.-Q.1    Yang, F.-L.2
  • 69
    • 77957279491 scopus 로고    scopus 로고
    • Synthesis of Lamivudine stearate and antiviral activity of stearic acid-g-chitosan oligosaccharide polymeric micelles delivery system
    • Li Q, Du Y-Z et al (2010) Synthesis of Lamivudine stearate and antiviral activity of stearic acid-g-chitosan oligosaccharide polymeric micelles delivery system. Eur J Pharm Sci 41:498-507
    • (2010) Eur J Pharm Sci , vol.41 , pp. 498-507
    • Li, Q.1    Du, Y.-Z.2
  • 70
    • 41549087356 scopus 로고    scopus 로고
    • Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin
    • DOI 10.1016/j.ejpb.2007.09.018, PII S0939641107003414
    • Hu F-Q, X-l Wu et al (2008) Cellular uptake and cytotoxicity of shell crosslinked stearic acidgrafted chitosan oligosaccharide micelles encapsulating doxorubicin. Eur J Pharm Biopharm 69:117-125 (Pubitemid 351467161)
    • (2008) European Journal of Pharmaceutics and Biopharmaceutics , vol.69 , Issue.1 , pp. 117-125
    • Hu, F.-Q.1    Wu, X.-l.2    Du, Y.-Z.3    You, J.4    Yuan, H.5
  • 71
    • 77950858414 scopus 로고    scopus 로고
    • Effect of molecular weight on the oleoyl-chitosan nanoparticles as carriers for doxorubicin
    • Zhang J, Chen XG et al (2010) Effect of molecular weight on the oleoyl-chitosan nanoparticles as carriers for doxorubicin. Colloids Surf B 77:125-130
    • (2010) Colloids Surf B , vol.77 , pp. 125-130
    • Zhang, J.1    Chen, X.G.2
  • 72
    • 34548623990 scopus 로고    scopus 로고
    • Effect of polymer molecular weight on the tumor targeting characteristics of self-assembled glycol chitosan nanoparticles
    • DOI 10.1016/j.jconrel.2007.04.009, PII S0168365907001836, Proceedings of the Thirtheenth International Symposium on Recent Advances in Drug Delivery Systems
    • Park K, Kim JH et al (2007) Effect of polymer molecular weight on the tumor targeting characteristics of self-assembled glycol chitosan nanoparticles. J Control Release 122:305-314 (Pubitemid 47404663)
    • (2007) Journal of Controlled Release , vol.122 , Issue.3 , pp. 305-314
    • Park, K.1    Kim, J.-H.2    Nam, Y.S.3    Lee, S.4    Nam, H.Y.5    Kim, K.6    Park, J.H.7    Kim, I.-S.8    Choi, K.9    Kim, S.Y.10    Kwon, I.C.11
  • 73
    • 40649100957 scopus 로고    scopus 로고
    • Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice
    • Kim JH, Kim YS et al (2008) Antitumor efficacy of cisplatin-loaded glycol chitosan nanoparticles in tumor-bearing mice. J Control Release 127:41-49
    • (2008) J Control Release , vol.127 , pp. 41-49
    • Kim, J.H.1    Kim, Y.S.2
  • 74
    • 42749096481 scopus 로고    scopus 로고
    • Tumor targetability and antitumor effect of docetaxel-loaded hydrophobically modified glycol chitosan nanoparticles
    • Hwang HY, Kim IS et al (2008) Tumor targetability and antitumor effect of docetaxel-loaded hydrophobically modified glycol chitosan nanoparticles. J Control Release 128:23-31
    • (2008) J Control Release , vol.128 , pp. 23-31
    • Hwang, H.Y.1    Kim, I.S.2
  • 75
    • 44649196487 scopus 로고    scopus 로고
    • A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides
    • Park Y, Hong HY et al (2008) A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides. J Control Release 128:217-223
    • (2008) J Control Release , vol.128 , pp. 217-223
    • Park, Y.1    Hong, H.Y.2
  • 76
    • 39749160936 scopus 로고    scopus 로고
    • Self-aggregated nanoparticles of cholesterol-modified glycol chitosan conjugate: Preparation, characterization, and preliminary assessment as a new drug delivery carrier
    • Yu JM, Li YH et al (2008) Self-aggregated nanoparticles of cholesterol-modified glycol chitosan conjugate: Preparation, characterization, and preliminary assessment as a new drug delivery carrier. Eur Polym J 44:555-565
    • (2008) Eur Polym J , vol.44 , pp. 555-565
    • Yu, J.M.1    Li, Y.H.2
  • 77
    • 1242337376 scopus 로고    scopus 로고
    • Synthesis and characterization of a brush-like copolymer of polylactide grafted onto chitosan
    • DOI 10.1016/j.carres.2003.09.013
    • Liu Y, Tian F et al (2004) Synthesis and characterization of a brush-like copolymer of polylactide grafted onto chitosan. Carbohydr Res 339:845-851 (Pubitemid 38230892)
    • (2004) Carbohydrate Research , vol.339 , Issue.4 , pp. 845-851
    • Liu, Y.1    Tian, F.2    Hu, K.A.3
  • 78
    • 7544245647 scopus 로고    scopus 로고
    • Synthesis and characterization of chitosan-graft-polycaprolactone copolymers
    • Liu L, Li Y et al (2004) Synthesis and characterization of chitosan-graft-polycaprolactone copolymers. Eur Polym J 40:2739-2744
    • (2004) Eur Polym J , vol.40 , pp. 2739-2744
    • Liu, L.1    Li, Y.2
  • 79
    • 78649447564 scopus 로고    scopus 로고
    • Chitosan-polycaprolactone copolymer microspheres for transforming growth factor-[beta]1 delivery
    • Wu H, Wang S et al (2011) Chitosan-polycaprolactone copolymer microspheres for transforming growth factor-[beta]1 delivery. Colloids Surf B 82:602-608
    • (2011) Colloids Surf B , vol.82 , pp. 602-608
    • Wu, H.1    Wang, S.2
  • 80
    • 75749154748 scopus 로고    scopus 로고
    • Fabrication of cationic nanomicelle from chitosan-graftpolycaprolactone as the carrier of 7-ethyl-10-hydroxy-camptothecin
    • Duan K, Zhang X et al (2010) Fabrication of cationic nanomicelle from chitosan-graftpolycaprolactone as the carrier of 7-ethyl-10-hydroxy- camptothecin. Colloids Surf B 76:475-482
    • (2010) Colloids Surf B , vol.76 , pp. 475-482
    • Duan, K.1    Zhang, X.2
  • 82
    • 19944375811 scopus 로고    scopus 로고
    • Advances in chitin and chitosan modification through graft copolymerization: A comprehensive review
    • Zohuriaan-Mehr MJ (2005) Advances in chitin and chitosan modification through graft copolymerization: a comprehensive review. Iran Polym J 14:235-265 (Pubitemid 40750459)
    • (2005) Iranian Polymer Journal (English Edition) , vol.14 , Issue.3 , pp. 235-265
    • Zohuriaan-Mehr, M.J.1
  • 83
    • 33845901550 scopus 로고    scopus 로고
    • Self-catalysis of phthaloylchitosan for graft copolymerization of ε-caprolactone with chitosan
    • DOI 10.1002/marc.200600508
    • Liu L, Chen LX et al (2006) Self-catalysis of phthaloylchitosan for graft copolymerization of epsilon-caprolactone with chitosan. Macromol Rapid Commun 27:1988-1994 (Pubitemid 46025934)
    • (2006) Macromolecular Rapid Communications , vol.27 , Issue.23 , pp. 1988-1994
    • Liu, L.1    Chen, L.2    Fang, Y.3
  • 84
    • 23044432051 scopus 로고    scopus 로고
    • Preparation of chitosan-g-polycaprolactone copolymers through ring-opening polymerization of ε-caprolactone onto phthaloyl-protected chitosan
    • DOI 10.1002/bip.20261
    • Liu L, Wang YS et al (2005) Preparation of chitosan-g-polycaprolactone copolymers through ring-opening polymerization of epsilon-caprolactone onto phthaloyl-protected chitosan. Biopolymers 78:163-170 (Pubitemid 41140770)
    • (2005) Biopolymers , vol.78 , Issue.4 , pp. 163-170
    • Liu, L.1    Wang, Y.2    Shen, X.3    Fang, Y.4
  • 85
    • 78650342690 scopus 로고    scopus 로고
    • Effect of PEGylation on the toxicity and permeability enhancement of chitosan
    • Casettari L, Vllasaliu D et al (2010) Effect of PEGylation on the toxicity and permeability enhancement of chitosan. Biomacromolecules 11:2854-2865
    • (2010) Biomacromolecules , vol.11 , pp. 2854-2865
    • Casettari, L.1    Vllasaliu, D.2
  • 86
    • 65149090527 scopus 로고    scopus 로고
    • A facile route for regioselective conjugation of organo-soluble polymers onto chitosan
    • Cai G, Jiang H et al (2009) A facile route for regioselective conjugation of organo-soluble polymers onto chitosan. Macromol Biosci 9:256-261
    • (2009) Macromol Biosci , vol.9 , pp. 256-261
    • Cai, G.1    Jiang, H.2
  • 87
    • 0037931475 scopus 로고    scopus 로고
    • Controlled hydrophobic/hydrophilicity of chitosan for spheres without specific processing technique
    • DOI 10.1002/bip.10400
    • Yoksan R, Akashi M et al (2003) Controlled hydrophobic/hydrophilicity of chitosan for spheres without specific processing technique. Biopolymers 69:386-390 (Pubitemid 36841401)
    • (2003) Biopolymers , vol.69 , Issue.3 , pp. 386-390
    • Yoksan, R.1    Akashi, M.2    Hiwatari, K.-I.3    Chirachanchai, S.4
  • 88
    • 1642381422 scopus 로고    scopus 로고
    • Synthesis and study of water-soluble chitosan-O-poly (ethylene glycol) graft copolymers
    • Gorochovceva N, Makuska R (2004) Synthesis and study of water-soluble chitosan-O-poly (ethylene glycol) graft copolymers. Eur Polym J 40:685-691
    • (2004) Eur Polym J , vol.40 , pp. 685-691
    • Gorochovceva, N.1    Makuska, R.2
  • 90
    • 0031516194 scopus 로고    scopus 로고
    • Graft copolymers of poly(ethylene glycol) (PEG) and chitosan
    • Saito H, Wu XD et al (1997) Graft copolymers of poly(ethylene glycol) (PEG) and chitosan. Macromol Rapid Commun 18:547-550
    • (1997) Macromol Rapid Commun , vol.18 , pp. 547-550
    • Saito, H.1    Wu, X.D.2
  • 91
    • 0032188404 scopus 로고    scopus 로고
    • Aggregation phenomenon of PEG-grafted chitosan in aqueous solution
    • PII S0032386197100209
    • Ouchi T, Nishizawa H et al (1998) Aggregation phenomenon of PEG-grafted chitosan in aqueous solution. Polymer 39:5171-5175 (Pubitemid 128369402)
    • (1998) Polymer , vol.39 , Issue.21 , pp. 5171-5175
    • Ouchi, T.1    Nishizawa, H.2    Ohya, Y.3
  • 92
    • 57349185627 scopus 로고    scopus 로고
    • Synthesis and self-assembly of chitosan-based copolymer with a pair of hydrophobic/hydrophilic grafts of polycaprolactone and poly(ethylene glycol)
    • Liu L, Xu X et al (2009) Synthesis and self-assembly of chitosan-based copolymer with a pair of hydrophobic/hydrophilic grafts of polycaprolactone and poly(ethylene glycol). Carbohydr Polym 75:401-407
    • (2009) Carbohydr Polym , vol.75 , pp. 401-407
    • Liu, L.1    Xu, X.2
  • 94
    • 67349272304 scopus 로고    scopus 로고
    • Wet chemical synthesis of chitosan hydrogelhydroxyapatite composite membranes for tissue engineering applications
    • Madhumathi K, Shalumon KT et al (2009) Wet chemical synthesis of chitosan hydrogelhydroxyapatite composite membranes for tissue engineering applications. Int J Biol Macromol 45:12-15
    • (2009) Int J Biol Macromol , vol.45 , pp. 12-15
    • Madhumathi, K.1    Shalumon, K.T.2
  • 95
    • 16344387352 scopus 로고    scopus 로고
    • PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release
    • DOI 10.1016/j.jconrel.2004.12.019
    • Bhattarai N, Ramay HR et al (2005) PEG-grafted chitosan as an injectable thermosensitive hydrogel for sustained protein release. J Control Release 103:609-624 (Pubitemid 40471019)
    • (2005) Journal of Controlled Release , vol.103 , Issue.3 , pp. 609-624
    • Bhattarai, N.1    Ramay, H.R.2    Gunn, J.3    Matsen, F.A.4    Zhang, M.5
  • 96
    • 36048968185 scopus 로고    scopus 로고
    • Synthesis and characterization of in situ chitosan-based hydrogel via grafting of carboxyethyl acrylate
    • Kim MS, Choi YJ et al (2007) Synthesis and characterization of in situ chitosan-based hydrogel via grafting of carboxyethyl acrylate. J Biomed Mater Res A 83A:674-682
    • (2007) J Biomed Mater Res A , vol.83 A , pp. 674-682
    • Kim, M.S.1    Choi, Y.J.2
  • 97
    • 77956642368 scopus 로고    scopus 로고
    • Hydrogels based on dual curable chitosan-graft-polyethylene glycol-graft-methacrylate: Application to layer-by-layer cell encapsulation
    • Poon YF, Cao Y et al (2010) Hydrogels based on dual curable chitosan-graft-polyethylene glycol-graft-methacrylate: application to layer-by-layer cell encapsulation. ACS Appl Mater Interfaces 2:2012-2025
    • (2010) ACS Appl Mater Interfaces , vol.2 , pp. 2012-2025
    • Poon, Y.F.1    Cao, Y.2
  • 98
    • 79251547046 scopus 로고    scopus 로고
    • Characterization of ph-and thermosensitive hydrogel as a vehicle for controlled protein delivery
    • Shi W, Ji Y et al (2010) Characterization of ph-and thermosensitive hydrogel as a vehicle for controlled protein delivery. J Pharm Sci 100(3):886-895
    • (2010) J Pharm Sci , vol.100 , Issue.3 , pp. 886-895
    • Shi, W.1    Ji, Y.2
  • 99
    • 67349148917 scopus 로고    scopus 로고
    • Unconfined compression properties of a porous poly(vinyl alcohol)-chitosan-based hydrogel after hydration
    • Lee SY, Pereira BP et al (2009) Unconfined compression properties of a porous poly(vinyl alcohol)-chitosan-based hydrogel after hydration. Acta Biomater 5:1919-1925
    • (2009) Acta Biomater , vol.5 , pp. 1919-1925
    • Lee, S.Y.1    Pereira, B.P.2
  • 100
    • 77957670564 scopus 로고    scopus 로고
    • An in situ formed biodegradable hydrogel for reconstruction of the corneal endothelium
    • Liang Y, Liu WS et al (2011) An in situ formed biodegradable hydrogel for reconstruction of the corneal endothelium. Colloids Surf B 82:1-7
    • (2011) Colloids Surf B , vol.82 , pp. 1-7
    • Liang, Y.1    Liu, W.S.2
  • 101
    • 60849104777 scopus 로고    scopus 로고
    • Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering
    • Tan HP, Chu CR et al (2009) Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering. Biomaterials 30:2499-2506
    • (2009) Biomaterials , vol.30 , pp. 2499-2506
    • Tan, H.P.1    Chu, C.R.2
  • 102
    • 67349280144 scopus 로고    scopus 로고
    • Thermosensitive chitosan-pluronic hydrogel as an injectable cell delivery carrier for cartilage regeneration
    • Park KM, Lee SY et al (2009) Thermosensitive chitosan-pluronic hydrogel as an injectable cell delivery carrier for cartilage regeneration. Acta Biomater 5:1956-1965
    • (2009) Acta Biomater , vol.5 , pp. 1956-1965
    • Park, K.M.1    Lee, S.Y.2
  • 103
    • 59449106806 scopus 로고    scopus 로고
    • Cell adhesion and accelerated detachment on the surface of temperature-sensitive chitosan and poly(N-isopropylacrylamide) hydrogels
    • Wang JY, Chen L et al (2009) Cell adhesion and accelerated detachment on the surface of temperature-sensitive chitosan and poly(N-isopropylacrylamide) hydrogels. J Mater Sci Mater Med 20:583-590
    • (2009) J Mater Sci Mater Med , vol.20 , pp. 583-590
    • Wang, J.Y.1    Chen, L.2
  • 104
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy-promises, problems and prospects
    • Verma IM, Somia N (1997) Gene therapy-promises, problems and prospects. Nature 389:239-242
    • (1997) Nature , vol.389 , pp. 239-242
    • Verma, I.M.1    Somia, N.2
  • 105
    • 0031918779 scopus 로고    scopus 로고
    • Non-viral gene delivery systems-preface
    • Rolland A, Felgner PL (1998) Non-viral gene delivery systems-preface. Adv Drug Deliv Rev 30:1-3
    • (1998) Adv Drug Deliv Rev , vol.30 , pp. 1-3
    • Rolland, A.1    Felgner, P.L.2
  • 106
    • 75149133614 scopus 로고    scopus 로고
    • Chitosan-based formulations for delivery of DNA and siRNA
    • Mao SR, Sun W et al (2010) Chitosan-based formulations for delivery of DNA and siRNA. Adv Drug Deliv Rev 62:12-27
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 12-27
    • Mao, S.R.1    Sun, W.2
  • 107
    • 77955113615 scopus 로고    scopus 로고
    • Targeted gene silencing using RGD-labeled chitosan nanoparticles
    • Han HD, Mangala LS et al (2010) Targeted gene silencing using RGD-labeled chitosan nanoparticles. Clin Cancer Res 16:3910-3922
    • (2010) Clin Cancer Res , vol.16 , pp. 3910-3922
    • Han, H.D.1    Mangala, L.S.2
  • 109
    • 33749844509 scopus 로고    scopus 로고
    • Development and characterisation of chitosan nanoparticles for siRNA delivery
    • DOI 10.1016/j.jconrel.2006.07.021, PII S0168365906003683
    • Katas H, Alpar HO (2006) Development and characterisation of chitosan nanoparticles for siRNA delivery. J Control Release 115:216-225 (Pubitemid 44559708)
    • (2006) Journal of Controlled Release , vol.115 , Issue.2 , pp. 216-225
    • Katas, H.1    Alpar, H.O.2
  • 110
    • 70350208807 scopus 로고    scopus 로고
    • Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery
    • Csaba N, Koping-Hoggard M et al (2009) Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery. Int J Pharm 382:205-214
    • (2009) Int J Pharm , vol.382 , pp. 205-214
    • Csaba, N.1    Koping-Hoggard, M.2
  • 111
    • 77957569447 scopus 로고    scopus 로고
    • Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes
    • Thibault M, Nimesh S et al (2010) Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes. Mol Ther 18:1787-1795
    • (2010) Mol Ther , vol.18 , pp. 1787-1795
    • Thibault, M.1    Nimesh, S.2
  • 113
    • 33646133667 scopus 로고    scopus 로고
    • Transfection of primary chondrocytes using chitosan-pEGFP nanoparticles
    • Zhao X, Yu SB et al (2006) Transfection of primary chondrocytes using chitosan-pEGFP nanoparticles. J Control Release 112:223-228
    • (2006) J Control Release , vol.112 , pp. 223-228
    • Zhao, X.1    Yu, S.B.2
  • 114
    • 61349123258 scopus 로고    scopus 로고
    • Nucleic acid delivery with chitosan and its derivatives
    • Lai WF, Lin MCM (2009) Nucleic acid delivery with chitosan and its derivatives. J Control Release 134:158-168
    • (2009) J Control Release , vol.134 , pp. 158-168
    • Lai, W.F.1    Lin, M.C.M.2
  • 115
    • 70349162856 scopus 로고    scopus 로고
    • Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone
    • Moreira C, Oliveira H et al (2009) Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone. Acta Biomater 5:2995-3006
    • (2009) Acta Biomater , vol.5 , pp. 2995-3006
    • Moreira, C.1    Oliveira, H.2
  • 116
    • 35848961651 scopus 로고    scopus 로고
    • Nanocarriers
    • DOI 10.1007/s11095-007-9463-5
    • Torchilin VP (2007) Nanocarriers. Pharmaceut Res 24:2333-2334 (Pubitemid 350060725)
    • (2007) Pharmaceutical Research , vol.24 , Issue.12 , pp. 2333-2334
    • Torchilin, V.P.1
  • 117
    • 36849001337 scopus 로고    scopus 로고
    • Thiolated chitosans: Development and in vitro evaluation of an oral tobramycin sulphate delivery system
    • DOI 10.1016/j.ejps.2007.09.001, PII S0928098707003569
    • Hombach J, Hoyer H et al (2008) Thiolated chitosans: development and in vitro evaluation of an oral tobramycin sulphate delivery system. Eur J Pharm Sci 33:1-8 (Pubitemid 350235186)
    • (2008) European Journal of Pharmaceutical Sciences , vol.33 , Issue.1 , pp. 1-8
    • Hombach, J.1    Hoyer, H.2    Bernkop-Schnurch, A.3
  • 118
    • 70449705990 scopus 로고    scopus 로고
    • Hydrotropic oligomer-conjugated glycol chitosan as a carrier of paclitaxel: Synthesis, characterization, and in vivo biodistribution
    • Saravanakumar G, Min KH et al (2009) Hydrotropic oligomer-conjugated glycol chitosan as a carrier of paclitaxel: Synthesis, characterization, and in vivo biodistribution. J Control Release 140:210-217
    • (2009) J Control Release , vol.140 , pp. 210-217
    • Saravanakumar, G.1    Min, K.H.2
  • 119
    • 62849083225 scopus 로고    scopus 로고
    • Synthesis and evaluation of lauryl succinyl chitosan particles towards oral insulin delivery and absorption
    • Rekha MR, Sharma CP (2009) Synthesis and evaluation of lauryl succinyl chitosan particles towards oral insulin delivery and absorption. J Control Release 135:144-151
    • (2009) J Control Release , vol.135 , pp. 144-151
    • Rekha, M.R.1    Sharma, C.P.2
  • 121
    • 70349276692 scopus 로고    scopus 로고
    • Incorporation methods for cholic acid chitosan-g-mPEG self-assembly micellar system containing camptothecin
    • Ngawhirunpat T, Wonglertnirant N et al (2009) Incorporation methods for cholic acid chitosan-g-mPEG self-assembly micellar system containing camptothecin. Colloids Surf B 74:253-259
    • (2009) Colloids Surf B , vol.74 , pp. 253-259
    • Ngawhirunpat, T.1    Wonglertnirant, N.2
  • 122
    • 77952692576 scopus 로고    scopus 로고
    • Cholesterol succinyl chitosan anchored liposomes: Preparation, characterization, physical stability, and drug release behavior
    • Wang Y, Tu S et al (2010) Cholesterol succinyl chitosan anchored liposomes: preparation, characterization, physical stability, and drug release behavior. Nanomed Nanotechnol Biol Med 6:471-477
    • (2010) Nanomed Nanotechnol Biol Med , vol.6 , pp. 471-477
    • Wang, Y.1    Tu, S.2
  • 123
    • 77953476310 scopus 로고    scopus 로고
    • Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin
    • Zhou Y-Y, Du Y-Z et al (2010) Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin. Int J Pharm 393:144-152
    • (2010) Int J Pharm , vol.393 , pp. 144-152
    • Zhou, Y.-Y.1    Du, Y.-Z.2
  • 124
    • 54949141087 scopus 로고    scopus 로고
    • PEGylated chitosan-based polymer micelle as an intracellular delivery carrier for anti-tumor targeting therapy
    • Hu F-Q, Meng P et al (2008) PEGylated chitosan-based polymer micelle as an intracellular delivery carrier for anti-tumor targeting therapy. Eur J Pharm Biopharm 70:749-757
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 749-757
    • Hu, F.-Q.1    Meng, P.2
  • 125
    • 62749114279 scopus 로고    scopus 로고
    • Self-assembled micelles of N-phthaloylchitosan-g-polyvinylpyrrolidone for drug delivery
    • Bian F, Jia L et al (2009) Self-assembled micelles of N-phthaloylchitosan-g-polyvinylpyrrolidone for drug delivery. Carbohydr Polym 76:454-459
    • (2009) Carbohydr Polym , vol.76 , pp. 454-459
    • Bian, F.1    Jia, L.2
  • 126
    • 78649577466 scopus 로고    scopus 로고
    • Chitosan-poly(epsilon-caprolactone)-poly(ethylene glycol) graft copolymers: Synthesis, self-assembly, and drug release behavior
    • Chen C, Cai GQ et al (2011) Chitosan-poly(epsilon-caprolactone)- poly(ethylene glycol) graft copolymers: synthesis, self-assembly, and drug release behavior. J Biomed Mater Res A 96A:116-124
    • (2011) J Biomed Mater Res A , vol.96 A , pp. 116-124
    • Chen, C.1    Cai, G.Q.2
  • 127
    • 65149098527 scopus 로고    scopus 로고
    • Synthesis, characterization and self-assemble behavior of chitosan-O-poly([epsilon]-caprolactone)
    • Cai G, Jiang H et al (2009) Synthesis, characterization and self-assemble behavior of chitosan-O-poly([epsilon]-caprolactone). Eur Polym J 45:1674-1680
    • (2009) Eur Polym J , vol.45 , pp. 1674-1680
    • Cai, G.1    Jiang, H.2
  • 128
    • 34547823037 scopus 로고    scopus 로고
    • Novel amphiphilic ternary polysaccharide derivates chitosan-g-PCL-b-MPEG: Synthesis, characterization, and aggregation in aqueous solution
    • DOI 10.1002/bip.20743
    • Lu Y, Liu L et al (2007) Novel amphiphilic ternary polysaccharide derivates chitosan-g-PCL-b-MPEG: synthesis, characterization, and aggregation in aqueous solution. Biopolymers 86:403-408 (Pubitemid 47237807)
    • (2007) Biopolymers , vol.86 , Issue.5-6 , pp. 403-408
    • Lu, Y.1    Liu, L.2    Guo, S.3
  • 129
    • 77949888510 scopus 로고    scopus 로고
    • Biocompatibility evaluation of chitosan-based injectable hydrogels for the culturing mice mesenchymal stem cells in vitro
    • Yan JH, Yang L et al (2010) Biocompatibility evaluation of chitosan-based injectable hydrogels for the culturing mice mesenchymal stem cells in vitro. J Biomater Appl 24:625-637
    • (2010) J Biomater Appl , vol.24 , pp. 625-637
    • Yan, J.H.1    Yang, L.2
  • 130
    • 77149176921 scopus 로고    scopus 로고
    • The preparation and cytocompatibility of injectable thermosensitive chitosan/poly(vinyl alcohol) hydrogel
    • Qi B, Yu A et al (2010) The preparation and cytocompatibility of injectable thermosensitive chitosan/poly(vinyl alcohol) hydrogel. J Huazhong Univ Sci Technolog Med Sci 30:89-93
    • (2010) J Huazhong Univ Sci Technolog Med Sci , vol.30 , pp. 89-93
    • Qi, B.1    Yu, A.2
  • 134
    • 77649275722 scopus 로고    scopus 로고
    • A chitosan/beta-glycerophosphate thermo-sensitive gel for the delivery of ellagic acid for the treatment of brain cancer
    • Kim S, Nishimoto SK et al (2010) A chitosan/beta-glycerophosphate thermo-sensitive gel for the delivery of ellagic acid for the treatment of brain cancer. Biomaterials 31:4157-66
    • (2010) Biomaterials , vol.31 , pp. 4157-66
    • Kim, S.1    Nishimoto, S.K.2
  • 136
    • 78349308986 scopus 로고    scopus 로고
    • Preparation, fabrication and biocompatibility of novel injectable temperature-sensitive chitosan/glycerophosphate/collagen hydrogels
    • Song K, QiaoMet al (2010) Preparation, fabrication and biocompatibility of novel injectable temperature-sensitive chitosan/glycerophosphate/collagen hydrogels. J Mater Sci Mater Med 21:2835-42
    • (2010) J Mater Sci Mater Med , vol.21 , pp. 2835-42
    • Song, K.1    Qiao, M.2
  • 139
    • 77951950071 scopus 로고    scopus 로고
    • Evaluation of the chitosan/glycerol-beta-phosphate disodium salt hydrogel application in peripheral nerve regeneration
    • Zheng L, Ao Q et al (2010) Evaluation of the chitosan/glycerol-beta- phosphate disodium salt hydrogel application in peripheral nerve regeneration. Biomed Mater 5:35003
    • (2010) Biomed Mater , vol.5 , pp. 35003
    • Zheng, L.1    Ao, Q.2
  • 140
    • 77950809834 scopus 로고    scopus 로고
    • Both the transplantation of somatic cell nuclear transfer-and fertilization-derived mouse embryonic stem cells with temperature-responsive chitosan hydrogel improve myocardial performance in infarcted rat hearts
    • Lu S, Wang H et al (2010) Both the transplantation of somatic cell nuclear transfer-and fertilization-derived mouse embryonic stem cells with temperature-responsive chitosan hydrogel improve myocardial performance in infarcted rat hearts. Tissue Eng A 16:1303-15
    • (2010) Tissue Eng A , vol.16 , pp. 1303-1315
    • Lu, S.1    Wang, H.2
  • 141
    • 77955709587 scopus 로고    scopus 로고
    • Improved myocardial performance in infarcted rat heart by co-injection of basic fibroblast growth factor with temperature-responsive chitosan hydrogel
    • Wang H, Zhang X et al (2010) Improved myocardial performance in infarcted rat heart by co-injection of basic fibroblast growth factor with temperature-responsive chitosan hydrogel. J Heart Lung Transplant 29:881-7
    • (2010) J Heart Lung Transplant , vol.29 , pp. 881-887
    • Wang, H.1    Zhang, X.2
  • 142
    • 79952193036 scopus 로고    scopus 로고
    • Fabrication and characterization of tunable polysaccharide hydrogel blends for neural repair
    • Zuidema JM, Pap MM et al (2010) Fabrication and characterization of tunable polysaccharide hydrogel blends for neural repair. Acta Biomater 7(4):1634-1643
    • (2010) Acta Biomater , vol.7 , Issue.4 , pp. 1634-1643
    • Zuidema, J.M.1    Pap, M.M.2
  • 143
    • 77952889058 scopus 로고    scopus 로고
    • Potential of an injectable chitosan/starch/beta-glycerol phosphate hydrogel for sustaining normal chondrocyte function
    • Ngoenkam J, Faikrua A et al (2010) Potential of an injectable chitosan/starch/beta-glycerol phosphate hydrogel for sustaining normal chondrocyte function. Int J Pharm 391:115-24
    • (2010) Int J Pharm , vol.391 , pp. 115-124
    • Ngoenkam, J.1    Faikrua, A.2
  • 144
    • 77952743791 scopus 로고    scopus 로고
    • Gel characterisation and in vivo evaluation of minocyclineloaded wound dressing with enhanced wound healing using polyvinyl alcohol and chitosan
    • Sung JH, Hwang MR et al (2010) Gel characterisation and in vivo evaluation of minocyclineloaded wound dressing with enhanced wound healing using polyvinyl alcohol and chitosan. Int J Pharm 392:232-40
    • (2010) Int J Pharm , vol.392 , pp. 232-240
    • Sung, J.H.1    Hwang, M.R.2
  • 145
    • 70450198618 scopus 로고    scopus 로고
    • A thermosensitive chitosan/poly(vinyl alcohol) hydrogel containing hydroxyapatite for protein delivery
    • Tang Y, Du Y et al (2009) A thermosensitive chitosan/poly(vinyl alcohol) hydrogel containing hydroxyapatite for protein delivery. J Biomed Mater Res A 91:953-63
    • (2009) J Biomed Mater Res A , vol.91 , pp. 953-963
    • Tang, Y.1    Du, Y.2
  • 146
    • 36248989188 scopus 로고    scopus 로고
    • Chitosan and its derivatives for tissue engineering applications
    • Kim IY, Seo SJ et al (2008) Chitosan and its derivatives for tissue engineering applications. Biotechnol Adv 26:1-21
    • (2008) Biotechnol Adv , vol.26 , pp. 1-21
    • Kim, I.Y.1    Seo, S.J.2
  • 147
    • 67349126483 scopus 로고    scopus 로고
    • Disulfide-crosslinked chitosan hydrogel for cell viability and controlled protein release
    • Wu ZM, Zhang XG et al (2009) Disulfide-crosslinked chitosan hydrogel for cell viability and controlled protein release. Eur J Pharm Sci 37:198-206
    • (2009) Eur J Pharm Sci , vol.37 , pp. 198-206
    • Wu, Z.M.1    Zhang, X.G.2
  • 148
    • 77957670564 scopus 로고    scopus 로고
    • An in situ formed biodegradable hydrogel for reconstruction of the corneal endothelium
    • Liang Y, Liu W et al (2011) An in situ formed biodegradable hydrogel for reconstruction of the corneal endothelium. Colloids Surf B Biointerfaces 82:1-7
    • (2011) Colloids Surf B Biointerfaces , vol.82 , pp. 1-7
    • Liang, Y.1    Liu, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.