메뉴 건너뛰기




Volumn 24, Issue , 2015, Pages 7-11

The global challenge of new classes of antibacterial agents: An industry perspective

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; CEPHALOSPORIN DERIVATIVE; GENERIC DRUG; PENICILLIN DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TELITHROMYCIN; TETRACYCLINE DERIVATIVE; TROVAFLOXACIN; ANTIINFECTIVE AGENT;

EID: 84935002928     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2015.06.003     Document Type: Review
Times cited : (37)

References (49)
  • 3
    • 40549129995 scopus 로고    scopus 로고
    • Clinical and economic impact of common multidrug-resistant gram-negative bacilli
    • C.G. Giske, D.L. Monnet, O. Cars, and Y. Carmeli Clinical and economic impact of common multidrug-resistant gram-negative bacilli Antimicrob Agents Chemother 52 2008 813 821
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 813-821
    • Giske, C.G.1    Monnet, D.L.2    Cars, O.3    Carmeli, Y.4
  • 5
    • 84908577353 scopus 로고    scopus 로고
    • Antibiotic resistance-problems, progress, and prospects
    • C. Nathan, and O. Cars Antibiotic resistance-problems, progress, and prospects N Engl J Med 371 2014 1761 1763
    • (2014) N Engl J Med , vol.371 , pp. 1761-1763
    • Nathan, C.1    Cars, O.2
  • 10
    • 84901594817 scopus 로고    scopus 로고
    • A three-step plan for antibiotics
    • A three-step plan for antibiotics Nature 509 2014 533
    • (2014) Nature , vol.509 , pp. 533
  • 11
    • 84934909416 scopus 로고    scopus 로고
    • Federal officials, congress seek ways to stimulate antibiotic development
    • J.L. Fox Federal officials, congress seek ways to stimulate antibiotic development Microbe 10 2015 13 16
    • (2015) Microbe , vol.10 , pp. 13-16
    • Fox, J.L.1
  • 12
    • 84903766667 scopus 로고    scopus 로고
    • Policy: An intergovernmental panel on antimicrobial resistance
    • M. Woolhouse, and J. Farrar Policy: an intergovernmental panel on antimicrobial resistance Nature 509 2014 555 557
    • (2014) Nature , vol.509 , pp. 555-557
    • Woolhouse, M.1    Farrar, J.2
  • 14
    • 84934963503 scopus 로고    scopus 로고
    • New drugs way to avoid an antibiotic apocalypse
    • New drugs way to avoid an antibiotic apocalypse Financial Times 2015
    • (2015) Financial Times
  • 17
    • 79951634603 scopus 로고    scopus 로고
    • Control of lipopolysaccharide biosynthesis by FtsH-mediated proteolysis of LpxC is conserved in enterobacteria but not in all gram-negative bacteria
    • S. Langklotz, M. Schakermann, and F. Narberhaus Control of lipopolysaccharide biosynthesis by FtsH-mediated proteolysis of LpxC is conserved in enterobacteria but not in all gram-negative bacteria J Bacteriol 193 2011 1090 1097
    • (2011) J Bacteriol , vol.193 , pp. 1090-1097
    • Langklotz, S.1    Schakermann, M.2    Narberhaus, F.3
  • 18
    • 84255201077 scopus 로고    scopus 로고
    • Antibiotics in development targeting protein synthesis
    • J.A. Sutcliffe Antibiotics in development targeting protein synthesis Ann N Y Acad Sci 1241 2011 122 152
    • (2011) Ann N y Acad Sci , vol.1241 , pp. 122-152
    • Sutcliffe, J.A.1
  • 19
    • 72249086358 scopus 로고    scopus 로고
    • Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections
    • T.V. Magee, S.L. Ripp, B. Li, R.A. Buzon, L. Chupak, T.J. Dougherty, S.M. Finegan, D. Girard, A.E. Hagen, M.J. Falcone, and et al. Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections J Med Chem 52 2009 7446 7457
    • (2009) J Med Chem , vol.52 , pp. 7446-7457
    • Magee, T.V.1    Ripp, S.L.2    Li, B.3    Buzon, R.A.4    Chupak, L.5    Dougherty, T.J.6    Finegan, S.M.7    Girard, D.8    Hagen, A.E.9    Falcone, M.J.10
  • 20
    • 84878278251 scopus 로고    scopus 로고
    • 10 x '20 Progress - Development of new drugs active against gram-negative bacilli: An update from the Infectious Diseases Society of America
    • H.W. Boucher, G.H. Talbot, D.K. Benjamin Jr., J. Bradley, R.J. Guidos, R.N. Jones, B.E. Murray, R.A. Bonomo, and D. Gilbert 10 x '20 Progress - development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America Clin Infect Dis 56 2013 1685 1694
    • (2013) Clin Infect Dis , vol.56 , pp. 1685-1694
    • Boucher, H.W.1    Talbot, G.H.2    Benjamin, D.K.3    Bradley, J.4    Guidos, R.J.5    Jones, R.N.6    Murray, B.E.7    Bonomo, R.A.8    Gilbert, D.9
  • 21
    • 77955351648 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides
    • D. Pavlovic, and S. Mutak Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides J Med Chem 53 2010 5868 5880
    • (2010) J Med Chem , vol.53 , pp. 5868-5880
    • Pavlovic, D.1    Mutak, S.2
  • 22
    • 84884276513 scopus 로고    scopus 로고
    • Improvement of the pharmacokinetics and in vivo antibacterial efficacy of a novel type IIa topoisomerase inhibitor by formulation in liposomes
    • A.B. Shapiro, J. Newman, K. Goteti, M.E. Beaudoin, R. Harrison, S. Hopkins, N. Agrawal, and O. Rivin Improvement of the pharmacokinetics and in vivo antibacterial efficacy of a novel type IIa topoisomerase inhibitor by formulation in liposomes Antimicrob Agents Chemother 57 2013 4816 4824
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 4816-4824
    • Shapiro, A.B.1    Newman, J.2    Goteti, K.3    Beaudoin, M.E.4    Harrison, R.5    Hopkins, S.6    Agrawal, N.7    Rivin, O.8
  • 23
    • 39749190058 scopus 로고    scopus 로고
    • Ceftobiprole: A new option for treatment of skin and soft-tissue infections due to methicillin-resistant Staphylococcus aureus
    • A.F. Widmer Ceftobiprole: a new option for treatment of skin and soft-tissue infections due to methicillin-resistant Staphylococcus aureus Clin Infect Dis 46 2008 656 658
    • (2008) Clin Infect Dis , vol.46 , pp. 656-658
    • Widmer, A.F.1
  • 24
    • 84934963984 scopus 로고    scopus 로고
    • Drug makers tiptoe back into antibiotic R&D
    • H. Plumridge Drug makers tiptoe back into antibiotic R&D Wall Street J 2014
    • (2014) Wall Street J
    • Plumridge, H.1
  • 25
    • 33845719937 scopus 로고    scopus 로고
    • Antibacterial discovery and development - The failure of success?
    • P. Fernandes Antibacterial discovery and development - the failure of success? Nat Biotechnol 24 2006 1497 1503
    • (2006) Nat Biotechnol , vol.24 , pp. 1497-1503
    • Fernandes, P.1
  • 29
    • 84910670192 scopus 로고    scopus 로고
    • Attributable healthcare utilization and cost of pneumonia due to drug-resistant streptococcus pneumonia: A cost analysis
    • C.A. Reynolds, J.A. Finkelstein, G.T. Ray, M.R. Moore, and S.S. Huang Attributable healthcare utilization and cost of pneumonia due to drug-resistant streptococcus pneumonia: a cost analysis Antimicrob Resist Infect Control 3 2014 16
    • (2014) Antimicrob Resist Infect Control , vol.3 , pp. 16
    • Reynolds, C.A.1    Finkelstein, J.A.2    Ray, G.T.3    Moore, M.R.4    Huang, S.S.5
  • 31
    • 79958139104 scopus 로고    scopus 로고
    • Synthesis and antibacterial activity of pentacyclines: A novel class of tetracycline analogs
    • C. Sun, D.K. Hunt, R.B. Clark, D. Lofland, W.J. O'Brien, L. Plamondon, and X.Y. Xiao Synthesis and antibacterial activity of pentacyclines: a novel class of tetracycline analogs J Med Chem 54 2011 3704 3731
    • (2011) J Med Chem , vol.54 , pp. 3704-3731
    • Sun, C.1    Hunt, D.K.2    Clark, R.B.3    Lofland, D.4    O'Brien, W.J.5    Plamondon, L.6    Xiao, X.Y.7
  • 33
    • 84905994821 scopus 로고    scopus 로고
    • The evolving role of chemical synthesis in antibacterial drug discovery
    • P.M. Wright, I.B. Seiple, and A.G. Myers The evolving role of chemical synthesis in antibacterial drug discovery Angew Chem Int Ed Engl 53 2014 8840 8869
    • (2014) Angew Chem Int Ed Engl , vol.53 , pp. 8840-8869
    • Wright, P.M.1    Seiple, I.B.2    Myers, A.G.3
  • 35
    • 84876223355 scopus 로고    scopus 로고
    • Single-dose safety, tolerability, and pharmacokinetics of the antibiotic GSK1322322, a novel peptide deformylase inhibitor
    • O.J. Naderer, E. Dumont, J. Zhu, M. Kurtinecz, and L.S. Jones Single-dose safety, tolerability, and pharmacokinetics of the antibiotic GSK1322322, a novel peptide deformylase inhibitor Antimicrob Agents Chemother 57 2013 2005 2009
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 2005-2009
    • Naderer, O.J.1    Dumont, E.2    Zhu, J.3    Kurtinecz, M.4    Jones, L.S.5
  • 38
    • 79957789430 scopus 로고    scopus 로고
    • Pharmaceutical technologies for enhancing oral bioavailability of poorly soluble drugs
    • Y.S. Krishnaiah Pharmaceutical technologies for enhancing oral bioavailability of poorly soluble drugs J Bioequiv Availab 2 2010 28 36
    • (2010) J Bioequiv Availab , vol.2 , pp. 28-36
    • Krishnaiah, Y.S.1
  • 39
    • 77955957827 scopus 로고    scopus 로고
    • Integrated analysis of CANVAS 1 and 2: Phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection
    • G.R. Corey, M. Wilcox, G.H. Talbot, H.D. Friedland, T. Baculik, G.W. Witherell, I. Critchley, A.F. Das, and D. Thye Integrated analysis of CANVAS 1 and 2: phase 3, multicenter, randomized, double-blind studies to evaluate the safety and efficacy of ceftaroline versus vancomycin plus aztreonam in complicated skin and skin-structure infection Clin Infect Dis 51 2010 641 650
    • (2010) Clin Infect Dis , vol.51 , pp. 641-650
    • Corey, G.R.1    Wilcox, M.2    Talbot, G.H.3    Friedland, H.D.4    Baculik, T.5    Witherell, G.W.6    Critchley, I.7    Das, A.F.8    Thye, D.9
  • 40
    • 84901948706 scopus 로고    scopus 로고
    • Phage therapy gets revitalized
    • S. Reardon Phage therapy gets revitalized Nature 510 2014 15 16
    • (2014) Nature , vol.510 , pp. 15-16
    • Reardon, S.1
  • 41
    • 84865690747 scopus 로고    scopus 로고
    • Anti-bacterial monoclonal antibodies: Back to the future?
    • M.B. Oleksiewicz, G. Nagy, and E. Nagy Anti-bacterial monoclonal antibodies: back to the future? Arch Biochem Biophys 526 2012 124 131
    • (2012) Arch Biochem Biophys , vol.526 , pp. 124-131
    • Oleksiewicz, M.B.1    Nagy, G.2    Nagy, E.3
  • 42
    • 84858381864 scopus 로고    scopus 로고
    • Modulating immunity as a therapy for bacterial infections
    • R.E. Hancock, A. Nijnik, and D.J. Philpott Modulating immunity as a therapy for bacterial infections Nat Rev Microbiol 10 2012 243 254
    • (2012) Nat Rev Microbiol , vol.10 , pp. 243-254
    • Hancock, R.E.1    Nijnik, A.2    Philpott, D.J.3
  • 43
    • 84928212486 scopus 로고    scopus 로고
    • Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: An observational cohort study
    • P.A. Waight, N.J. Andrews, S.N. Ladhani, C.L. Sheppard, M.P.E. Slack, and E. Miller Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study Lancet Infect Dis 15 2015 535 543
    • (2015) Lancet Infect Dis , vol.15 , pp. 535-543
    • Waight, P.A.1    Andrews, N.J.2    Ladhani, S.N.3    Sheppard, C.L.4    Slack, M.P.E.5    Miller, E.6
  • 44
    • 29244437540 scopus 로고    scopus 로고
    • Vancomycin: A history
    • D.P. Levine Vancomycin: a history Clin Infect Dis 42 Suppl 1 2006 S5 S12
    • (2006) Clin Infect Dis , vol.42 , pp. S5-S12
    • Levine, D.P.1
  • 45
    • 34247192001 scopus 로고    scopus 로고
    • The FDA and the case of Ketek
    • D.B. Ross The FDA and the case of Ketek N Engl J Med 356 2007 1601 1604
    • (2007) N Engl J Med , vol.356 , pp. 1601-1604
    • Ross, D.B.1
  • 46
    • 78649638491 scopus 로고    scopus 로고
    • Molecular characterization of off-target activities of telithromycin: A potential role for nicotinic acetylcholine receptors
    • D. Bertrand, S. Bertrand, E. Neveu, and P. Fernandes Molecular characterization of off-target activities of telithromycin: a potential role for nicotinic acetylcholine receptors Antimicrob Agents Chemother 54 2010 5399 5402
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 5399-5402
    • Bertrand, D.1    Bertrand, S.2    Neveu, E.3    Fernandes, P.4
  • 47
    • 84882620294 scopus 로고    scopus 로고
    • Decreased susceptibility to cephalosporins among gonococci: Data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in England and Wales, 2007-2011
    • C.A. Ison, K. Town, C. Obi, S. Chisholm, G. Hughes, D.M. Livermore, and C.M. Lowndes Decreased susceptibility to cephalosporins among gonococci: data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in England and Wales, 2007-2011 Lancet Infect Dis 13 2013 762 768
    • (2013) Lancet Infect Dis , vol.13 , pp. 762-768
    • Ison, C.A.1    Town, K.2    Obi, C.3    Chisholm, S.4    Hughes, G.5    Livermore, D.M.6    Lowndes, C.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.