메뉴 건너뛰기




Volumn 12, Issue , 2014, Pages

Systems Medicine: From molecular features and models to the clinic in COPD

(18)  Gomez Cabrero, David a   Menche, Jörg b,c   Cano, Isaac d   Abugessaisa, Imad a   Huertas Migueláñ, Mercedes e   Tenyi, Akos f   de Mas, Igor Marin f   Kiani, Narsis A a   Marabita, Francesco a   Falciani, Francesco g   Burrowes, Kelly h   Maier, Dieter i   Wagner, Peter j   Selivanov, Vitaly f   Cascante, Marta f   Roca, Josep d   Barabási, Albert László b,c,k,l,m   Tegnér, Jesper a  


Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE; BIOLOGICAL MARKER; OXYGEN;

EID: 84934998269     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/1479-5876-12-S2-S4     Document Type: Article
Times cited : (23)

References (70)
  • 1
    • 79551664973 scopus 로고    scopus 로고
    • A passage through systems biology to systems medicine: adoption of middle-out rational approaches towards the understanding of therapeutic outcomes in cancer
    • Majumder D, Mukherjee A: A passage through systems biology to systems medicine: adoption of middle-out rational approaches towards the understanding of therapeutic outcomes in cancer. The Analyst 2011, 136(4):663-78.
    • (2011) The Analyst , vol.136 , Issue.4 , pp. 663-678
    • Majumder, D.1    Mukherjee, A.2
  • 2
    • 84935013083 scopus 로고    scopus 로고
    • Synergy-COPD: A systems Approach for understanding and managing Chronic Diseases
    • the Synergy-Copd consortium
    • Gomez-Cabrero, David, Lluch-Ariet, Magi, Tegner Jesper, Cascante Marta, Miralles Felip, Roca Josep, the Synergy-COPD consortium: Synergy-COPD: A systems Approach for understanding and managing Chronic Diseases. Journal of Translational Medicine 2014, 12(Suppl 2):S2.
    • (2014) Journal of Translational Medicine , vol.12 , pp. S2
    • Gomez-Cabrero, D.1    Lluch-Ariet, M.2    Jesper, T.3    Marta, C.4    Felip, M.5    Josep, R.6
  • 9
    • 84883185155 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cell gene expression in chronic obstructive pulmonary disease
    • Aug
    • Bahr TM, Hughes GJ, Armstrong M, Reisdorph R, et al: Peripheral blood mononuclear cell gene expression in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol 2013, 49(2):316-23, Aug.
    • (2013) Am J Respir Cell Mol Biol , vol.49 , Issue.2 , pp. 316-323
    • Bahr, T.M.1    Hughes, G.J.2    Armstrong, M.3    Reisdorph, R.4
  • 10
    • 79952674000 scopus 로고    scopus 로고
    • Interactome networks and human disease
    • Vidal M, Cusick ME, Barabási AL: Interactome networks and human disease. Cell 2011, 144(6):986-98.
    • (2011) Cell , vol.144 , Issue.6 , pp. 986-998
    • Vidal, M.1    Cusick, M.E.2    Barabási, A.L.3
  • 11
    • 70249134919 scopus 로고    scopus 로고
    • Molecular networks as sensors and drivers of common human diseases
    • Schadt EE: Molecular networks as sensors and drivers of common human diseases. Nature 2009, 461:218-223.
    • (2009) Nature , vol.461 , pp. 218-223
    • Schadt, E.E.1
  • 12
    • 78650373804 scopus 로고    scopus 로고
    • Network medicine: a network-based approach to human disease
    • Genetics
    • Barabási AL, Gulbahce N, Loscalzo J: Network medicine: a network-based approach to human disease. In Nature reviews. Volume 12. Genetics; 2011:(1):56-68.
    • (2011) Nature reviews , vol.12 , Issue.1 , pp. 56-68
    • Barabási, A.L.1    Gulbahce, N.2    Loscalzo, J.3
  • 13
    • 41549139527 scopus 로고    scopus 로고
    • Walking the interactome for pri- oritization of candidate disease genes
    • Köhler S, et al: Walking the interactome for pri- oritization of candidate disease genes. The American Journal of Human Genetics 2008, 82:949-958.
    • (2008) The American Journal of Human Genetics , vol.82 , pp. 949-958
    • Köhler, S.1
  • 15
    • 84866130570 scopus 로고    scopus 로고
    • A network-based approach for predicting missing pathway interactions
    • Navlakha S, Gitter A, Bar-Joseph Z: A network-based approach for predicting missing pathway interactions. PLoS computational biology 2012, 8:e1002640.
    • (2012) PLoS computational biology , vol.8 , pp. e1002640
    • Navlakha, S.1    Gitter, A.2    Bar-Joseph, Z.3
  • 17
    • 84934901042 scopus 로고    scopus 로고
    • Protein-Protein Interaction Network Analysis in Chronic Obstructive Pulmonary Disease
    • Bao H, Wang J, Zhou D, Han Z, Su L, Zhang Y, Li Q: Protein-Protein Interaction Network Analysis in Chronic Obstructive Pulmonary Disease. Lung (2800) 2013.
    • (2013) Lung , Issue.2800
    • Bao, H.1    Wang, J.2    Zhou, D.3    Han, Z.4    Su, L.5    Zhang, Y.6    Li, Q.7
  • 18
    • 84907371840 scopus 로고    scopus 로고
    • A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease
    • Menche J, Sharma A, Cho MH, Mayer RJ, Rennard SI, Celli B, Barabási AL: A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease. BMC Systems Biology 2014, 8(Suppl 2):S8.
    • (2014) BMC Systems Biology , vol.8 , pp. S8
    • Menche, J.1    Sharma, A.2    Cho, M.H.3    Mayer, R.J.4    Rennard, S.I.5    Celli, B.6    Barabási, A.L.7
  • 19
    • 0141993704 scopus 로고    scopus 로고
    • A gene-coexpression network for global discovery of conserved genetic modules
    • Stuart JM, Segal E, Koller D, Kim SK: A gene-coexpression network for global discovery of conserved genetic modules. Science 2003, 302:249-255.
    • (2003) Science , vol.302 , pp. 249-255
    • Stuart, J.M.1    Segal, E.2    Koller, D.3    Kim, S.K.4
  • 20
    • 27144434505 scopus 로고    scopus 로고
    • The synthetic genetic interaction spectrum of essential genes
    • Davierwala, Armaity P, et al: The synthetic genetic interaction spectrum of essential genes. Nature genetics 2005, 37(10):1147-1152.
    • (2005) Nature genetics , vol.37 , Issue.10 , pp. 1147-1152
    • Davierwala, A.P.1
  • 22
    • 80053440986 scopus 로고    scopus 로고
    • A Systems Biology Approach Identifies Molecular Networks Defining Skeletal Muscle Abnormalities in Chronic Obstructive Pulmonary Disease
    • Turan N, Kalko S, Stincone A, Clarke K, Sabah A, Howlett K, Falciani F: A Systems Biology Approach Identifies Molecular Networks Defining Skeletal Muscle Abnormalities in Chronic Obstructive Pulmonary Disease. In PLoS Computational Biology S. Miyano 2011, 7(9):e1002129.
    • (2011) In PLoS Computational Biology S. Miyano , vol.7 , Issue.9 , pp. e1002129
    • Turan, N.1    Kalko, S.2    Stincone, A.3    Clarke, K.4    Sabah, A.5    Howlett, K.6    Falciani, F.7
  • 24
    • 74549117769 scopus 로고    scopus 로고
    • Bistability of mitochondrial respiration underlies paradoxical reactive oxygen species generation induced by anoxia
    • Selivanov Va, Votyakova TV, Zeak Ja, Trucco M, Roca J, Cascante M: Bistability of mitochondrial respiration underlies paradoxical reactive oxygen species generation induced by anoxia. PLoS Computational Biology 2009, 5(12):e1000619.
    • (2009) PLoS Computational Biology , vol.5 , Issue.12 , pp. e1000619
    • Selivanov, Va1    Votyakova, T.V.2    Zeak, Ja3    Trucco, M.4    Roca, J.5    Cascante, M.6
  • 25
    • 84935000057 scopus 로고    scopus 로고
    • ChainRank, a chain search based method for prioritization and contextualisation of biological sub-networks
    • Submitted
    • Ákos Tényi, Pedro de Atauri, David Gomez-Cabrero, Isaac Cano Isaac, Francesco Falciani Francesco, Marta Cascante Marta, Josep Roca, Dieter Maier: ChainRank, a chain search based method for prioritization and contextualisation of biological sub-networks. 2014, Submitted.
    • (2014)
    • Tényi, A.1    de Atauri, P.2    Gomez-Cabrero, D.3    Isaac, I.C.4    Francesco, F.F.5    Marta, M.C.6    Roca, J.7    Maier, D.8
  • 27
    • 0030478786 scopus 로고    scopus 로고
    • A theoretical analysis of factors determining VO2max at sea level and altitude
    • Wagner PD: A theoretical analysis of factors determining VO2max at sea level and altitude. Resp Physiol 1996a, 106(3):329-43.
    • (1996) Resp Physiol , vol.106 , Issue.3 , pp. 329-343
    • Wagner, P.D.1
  • 28
    • 0029918029 scopus 로고    scopus 로고
    • Determinants of maximal oxygen transport and utilization
    • Wagner PD: Determinants of maximal oxygen transport and utilization. Annual Review of Physiology 1996b, 58:21-50.
    • (1996) Annual Review of Physiology , vol.58 , pp. 21-50
    • Wagner, P.D.1
  • 29
    • 84864189746 scopus 로고    scopus 로고
    • Blood flow redistribution and ventilation-perfusion mismatch during embolic pulmonary arterial occlusion
    • Burrowes KS, Clark aR, Tawhai MH: Blood flow redistribution and ventilation-perfusion mismatch during embolic pulmonary arterial occlusion. Pulmonary Circulation 2011, 1(3):365-76.
    • (2011) Pulmonary Circulation , vol.1 , Issue.3 , pp. 365-376
    • Burrowes, K.S.1    Clark, A.R.2    Tawhai, M.H.3
  • 31
    • 84880079298 scopus 로고    scopus 로고
    • Oxidative stress in COPD
    • Kirkham Pa, Barnes PJ: Oxidative stress in COPD. Chest 2013, 144(1):266-73.
    • (2013) Chest , vol.144 , Issue.1 , pp. 266-273
    • Kirkham, Pa1    Barnes, P.J.2
  • 32
    • 84893771777 scopus 로고    scopus 로고
    • Cellular and Molecular Mechanisms of Chronic Obstructive Pulmonary Disease
    • Barnes PJ: Cellular and Molecular Mechanisms of Chronic Obstructive Pulmonary Disease. Clinics in Chest Medicine 2014, 35(1):71-86.
    • (2014) Clinics in Chest Medicine , vol.35 , Issue.1 , pp. 71-86
    • Barnes, P.J.1
  • 36
    • 84862197985 scopus 로고    scopus 로고
    • Predictive networks: a flexible, open source, web application for integration and analysis of human gene networks
    • Haibe-Kains B, Olsen C, Djebbari A, Bontempi G, Correll M, Bouton C, Quackenbush J: Predictive networks: a flexible, open source, web application for integration and analysis of human gene networks. Nucleic Acids Research 2012, 40(Database):D866-75.
    • (2012) Nucleic Acids Research , vol.40 , Issue.DATABASE , pp. D866-D875
    • Haibe-Kains, B.1    Olsen, C.2    Djebbari, A.3    Bontempi, G.4    Correll, M.5    Bouton, C.6    Quackenbush, J.7
  • 38
    • 84878150850 scopus 로고    scopus 로고
    • Skeletal muscle mitochondrial dysfunction during chronic obstructive pulmonary disease: central actor and therapeutic target
    • Meyer A, Zoll J, Charles AL, Charloux A, de Blay F, Diemunsch P, Sibilia J, Piquard F, Geny B: Skeletal muscle mitochondrial dysfunction during chronic obstructive pulmonary disease: central actor and therapeutic target. Exp Physiol 2013, 98(6):1063-78.
    • (2013) Exp Physiol , vol.98 , Issue.6 , pp. 1063-1078
    • Meyer, A.1    Zoll, J.2    Charles, A.L.3    Charloux, A.4    de Blay, F.5    Diemunsch, P.6    Sibilia, J.7    Piquard, F.8    Geny, B.9
  • 39
    • 4344571581 scopus 로고    scopus 로고
    • Rank products: A simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments
    • Breitling R, Armengaud P, Amtmann A, Herzyk P: Rank products: A simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. {FEBS} Letters 2004, 573(1-3):83-92.
    • (2004) {FEBS} Letters , vol.573 , Issue.1-3 , pp. 83-92
    • Breitling, R.1    Armengaud, P.2    Amtmann, A.3    Herzyk, P.4
  • 40
    • 33846796225 scopus 로고    scopus 로고
    • Ontology annotation: mapping genomic regions to biological function
    • Thomas PD, Mi H, Lewis S: Ontology annotation: mapping genomic regions to biological function. Curr Opin Chem Biol 2007, 11(1):4-11.
    • (2007) Curr Opin Chem Biol , vol.11 , Issue.1 , pp. 4-11
    • Thomas, P.D.1    Mi, H.2    Lewis, S.3
  • 42
    • 78651343711 scopus 로고    scopus 로고
    • DroID 2011 a comprehensive, integrated resource for protein, transcription factor RNA and gene interactions for Drosophila
    • Murali T, Pacifico S, Yu J, Guest S, Roberts GG 3rd, Finley RL Jr: DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila. Nucleic Acids Res 2011, 39(Database):D736-43.
    • (2011) Nucleic Acids Res , vol.39 , Issue.DATABASE , pp. D736-D743
    • Murali, T.1    Pacifico, S.2    Yu, J.3    Guest, S.4    Roberts, G.G.5    Finley, R.L.6
  • 43
    • 84894571860 scopus 로고    scopus 로고
    • Causal analysis approaches in Ingenuity Pathway Analysis
    • Krämer A, Green J, Pollard J Jr, Tugendreich S: Causal analysis approaches in Ingenuity Pathway Analysis. Bioinformatics 15 2014, 30(4):523-30.
    • (2014) Bioinformatics 15 , vol.30 , Issue.4 , pp. 523-530
    • Krämer, A.1    Green, J.2    Pollard, J.3    Tugendreich, S.4
  • 45
    • 84875466646 scopus 로고    scopus 로고
    • Mechanistic links between COPD and lung cancer
    • Houghton M: Mechanistic links between COPD and lung cancer. Nature Reviews Cancer 2013, 13(4):233-45.
    • (2013) Nature Reviews Cancer , vol.13 , Issue.4 , pp. 233-245
    • Houghton, M.1
  • 46
    • 84885109944 scopus 로고    scopus 로고
    • Cardiovascular comorbidity in COPD: systematic literature review
    • Müllerova H, Agusti A, Erqou S, Mapel DW: Cardiovascular comorbidity in COPD: systematic literature review. Chest 2013, 144(4):1163-78.
    • (2013) Chest , vol.144 , Issue.4 , pp. 1163-1178
    • Müllerova, H.1    Agusti, A.2    Erqou, S.3    Mapel, D.W.4
  • 51
    • 84859424158 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease
    • Decramer M, Janssens W, Miravitlles M: Chronic obstructive pulmonary disease. Lancet 2012, 379(9823):1341-51.
    • (2012) Lancet , vol.379 , Issue.9823 , pp. 1341-1351
    • Decramer, M.1    Janssens, W.2    Miravitlles, M.3
  • 54
    • 84866610404 scopus 로고    scopus 로고
    • Potential risk factors for medication non-adherence in patients with chronic obstructive pulmonary disease (COPD)
    • Khdour MR, Hawwa AF, Kidney JC, Smyth BM, McElnay JC: Potential risk factors for medication non-adherence in patients with chronic obstructive pulmonary disease (COPD). European Journal of Clinical Pharmacology 2012, 68(10):1365-73.
    • (2012) European Journal of Clinical Pharmacology , vol.68 , Issue.10 , pp. 1365-1373
    • Khdour, M.R.1    Hawwa, A.F.2    Kidney, J.C.3    Smyth, B.M.4    McElnay, J.C.5
  • 55
    • 84874986674 scopus 로고    scopus 로고
    • Cardiovascular disease in COPD: mechanisms
    • Maclay JD, MacNee W: Cardiovascular disease in COPD: mechanisms. Chest 2013, 143(3):798-807.
    • (2013) Chest , vol.143 , Issue.3 , pp. 798-807
    • Maclay, J.D.1    MacNee, W.2
  • 57
    • 84934886494 scopus 로고    scopus 로고
    • Josep Roca, the Synergy-COPD consortium: Predictive Medicine: Outcomes, Challenges and Opportunities in the Synergy-COPD project
    • Felip Miralles, David Gomez-Cabrero, Magi Lluch-Ariet, Jesper Tegnér, Marta Cascante, Josep Roca, the Synergy-COPD consortium: Predictive Medicine: Outcomes, Challenges and Opportunities in the Synergy-COPD project. Journal of Translational Medicine 2014, 12(Suppl 2):S12.
    • (2014) Journal of Translational Medicine , vol.12 , pp. S12
    • Miralles, F.1    Gomez-Cabrero, D.2    Lluch-Ariet, M.3    Tegnér, J.4    Cascante, M.5
  • 70
    • 84857047339 scopus 로고    scopus 로고
    • Phosphositeplus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
    • Hornbeck PV, Kornhauser JM, Tkachev S, Zhang B, Skrzypek E, Murray B, Latham V, Sullivan M: Phosphositeplus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse. Nucleic acids research 2012, 40:D261-D270.
    • (2012) Nucleic acids research , vol.40 , pp. D261-D270
    • Hornbeck, P.V.1    Kornhauser, J.M.2    Tkachev, S.3    Zhang, B.4    Skrzypek, E.5    Murray, B.6    Latham, V.7    Sullivan, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.