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Volumn 12, Issue 11, 2013, Pages 3398-3408

Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CYSTATHIONINE BETA SYNTHASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 84886753395     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M112.024851     Document Type: Article
Times cited : (31)

References (49)
  • 2
    • 78149263985 scopus 로고    scopus 로고
    • Genome-wide association studies of plasma lipids: Have we reached the limit?
    • Hegele, R. A. (2010) Genome-wide association studies of plasma lipids: have we reached the limit? Arterioscler. Thromb. Vasc. Biol. 30, 2084-2086.
    • (2010) Arterioscler. Thromb. Vasc. Biol. , vol.30 , pp. 2084-2086
    • Hegele, R.A.1
  • 5
    • 77950339092 scopus 로고    scopus 로고
    • Integrating pathway analysis and genetics of gene expression for ge- nome-wide association studies
    • Zhong, H., Yang, X., Kaplan, L. M., Molony, C., and Schadt, E. E. (2010) Integrating pathway analysis and genetics of gene expression for ge- nome-wide association studies. Am. J. Hum. Genet. 86, 581-591.
    • (2010) Am. J. Hum. Genet. , vol.86 , pp. 581-591
    • Zhong, H.1    Yang, X.2    Kaplan, L.M.3    Molony, C.4    Schadt, E.E.5
  • 7
    • 79851502150 scopus 로고    scopus 로고
    • Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology
    • Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Cotsapas, C., and Daly, M. J. (2011) Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet. 7, e1001273.
    • (2011) PLoS Genet. , vol.7
    • Rossin, E.J.1    Lage, K.2    Raychaudhuri, S.3    Xavier, R.J.4    Tatar, D.5    Benita, Y.6    Cotsapas, C.7    Daly, M.J.8
  • 9
    • 58949097433 scopus 로고    scopus 로고
    • CANDID: A flexible method for prioritizing candidate genes for complex human traits
    • Hutz, J. E., Kraja, A. T., McLeod, H. L., and Province, M. A. (2008) CANDID: A flexible method for prioritizing candidate genes for complex human traits. Genet. Epidemiol. 32, 779-790.
    • (2008) Genet. Epidemiol , vol.32 , pp. 779-790
    • Hutz, J.E.1    Kraja, A.T.2    McLeod, H.L.3    Province, M.A.4
  • 13
    • 0000801240 scopus 로고    scopus 로고
    • Discovering regulatory and signalling circuits in molecular interaction networks
    • Ideker, T., Ozier, O., Schwikowski, B., and Siegel, A. F. (2002) Discovering regulatory and signalling circuits in molecular interaction networks. Bioinformatics 18, S233-S240. (Pubitemid 41185658)
    • (2002) Bioinformatics , vol.18 , Issue.SUPPL. 1
    • Ideker, T.1    Ozier, O.2    Schwikowski, B.3    Siegel, A.F.4
  • 17
    • 68949204302 scopus 로고    scopus 로고
    • Strategies and issues in the detection of pathway enrichment in genomewide association studies
    • Hong, M. G., Pawitan, Y., Magnusson, P. K., and Prince, J. A. (2009) Strategies and issues in the detection of pathway enrichment in genomewide association studies. Hum. Genet. 126, 289-301.
    • (2009) Hum. Genet. , vol.126 , pp. 289-301
    • Hong, M.G.1    Pawitan, Y.2    Magnusson, P.K.3    Prince, J.A.4
  • 25
    • 84857503816 scopus 로고    scopus 로고
    • Gen rev: Exploring functional relevance of genes in molecular networks
    • Zheng, S., and Zhao, Z. (2012) Gen Rev: Exploring functional relevance of genes in molecular networks. Genomics 99, 183-188.
    • (2012) Genomics , vol.99 , pp. 183-188
    • Zheng, S.1    Zhao, Z.2
  • 26
    • 79952457046 scopus 로고    scopus 로고
    • Prediction of human disease-related gene clusters by clustering analysis
    • Sun, P. G., Gao, L., and Han, S. (2011) Prediction of human disease-related gene clusters by clustering analysis. Int. J. Biol. Sci. 7, 61-73.
    • (2011) Int. J. Biol. Sci. , vol.7 , pp. 61-73
    • Sun, P.G.1    Gao, L.2    Han, S.3
  • 27
    • 77956497662 scopus 로고    scopus 로고
    • Improving disease gene prioritization using the semantic similarity of gene ontology terms
    • Schlicker, A., Lengauer, T., and Albrecht, M. (2010) Improving disease gene prioritization using the semantic similarity of Gene Ontology terms. Bioinformatics 26, i561-i567.
    • (2010) Bioinformatics , vol.26
    • Schlicker, A.1    Lengauer, T.2    Albrecht, M.3
  • 28
    • 41549139527 scopus 로고    scopus 로고
    • Walking the interactome for prioritization of candidate disease genes
    • Kö hler, S., Bauer, S., Horn, D., and Robinson, P. N. (2008) Walking the interactome for prioritization of candidate disease genes. Am. J. Hum. Genet. 82, 949-958.
    • (2008) Am. J. Hum. Genet. , vol.82 , pp. 949-958
    • Kö Hler, S.1    Bauer, S.2    Horn, D.3    Robinson, P.N.4
  • 31
    • 38549141226 scopus 로고    scopus 로고
    • Joint annotation of coding and non-coding single nucleotide polymorphisms and mutations in the SNPeffect and PupaSuite databases
    • DOI 10.1093/nar/gkm979
    • Reumers, J., Conde, L., Medina, I., Maurer-Stroh, S., Van Durme, J., Dopazo, J., Rousseau, F., and Schymkowitz, J. (2008) Joint annotation of coding and non-coding single nucleotide polymorphisms and mutations in the SNPeffect and PupaSuite databases. Nucleic Acids Res. 36, D825-D829. (Pubitemid 351149830)
    • (2008) Nucleic Acids Research , vol.36 , Issue.SUPPL. 1
    • Reumers, J.1    Conde, L.2    Medina, I.3    Maurer-Stroh, S.4    Van Durme, J.5    Dopazo, J.6    Rousseau, F.7    Schymkowitz, J.8
  • 33
    • 0026562564 scopus 로고
    • Stroke registry in malmo, sweden
    • Jerntorp, P., and Berglund, G. (1992) Stroke registry in Malmo, Sweden. Stroke 23, 357-361.
    • (1992) Stroke , vol.23 , pp. 357-361
    • Jerntorp, P.1    Berglund, G.2
  • 35
    • 24044440971 scopus 로고    scopus 로고
    • BiNGO: A Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks
    • DOI 10.1093/bioinformatics/bti551
    • Maere, S., Heymans, K., and Kuiper, M. (2005) BiNGO: A Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics 21, 3448-3449. (Pubitemid 41222459)
    • (2005) Bioinformatics , vol.21 , Issue.16 , pp. 3448-3449
    • Maere, S.1    Heymans, K.2    Kuiper, M.3
  • 36
    • 78650373804 scopus 로고    scopus 로고
    • Network medicine: A network-based approach to human disease
    • Barabá si, A. L., Gulbahce, N., and Loscalzo, J. (2011) Network medicine: A network-based approach to human disease. Nat. Rev. Genet. 12, 56-68.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 56-68
    • Barabási, A.L.1    Gulbahce, N.2    Loscalzo, J.3
  • 39
    • 77951952127 scopus 로고    scopus 로고
    • The power of protein interaction networks for associating genes with diseases
    • Navlakha, S., and Kingsford, C. (2010) The power of protein interaction networks for associating genes with diseases. Bioinformatics 26, 1057-1063.
    • (2010) Bioinformatics , vol.26 , pp. 1057-1063
    • Navlakha, S.1    Kingsford, C.2
  • 41
    • 11144230938 scopus 로고    scopus 로고
    • Abnormal lipid metabolism in cystathionine β-synthase-deficient mice, an animal model for hyperhomocysteinemia
    • DOI 10.1074/jbc.M406820200
    • Namekata, K., Enokido, Y., Ishii, I., Nagai, Y., Harada, T., and Kimura, H. (2004) Abnormal lipid metabolism in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia. J. Biol. Chem. 279, 52961-52969. (Pubitemid 40051794)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.51 , pp. 52961-52969
    • Namekata, K.1    Enokido, Y.2    Ishii, I.3    Nagai, Y.4    Harada, T.5    Kimura, H.6
  • 42
    • 76849085218 scopus 로고    scopus 로고
    • Deletion of the FHL2 gene attenuates the formation of atherosclerotic lesions after a cholesterol-enriched diet
    • Chu, P. H., Yeh, H. I., Wu, H. H., Hong, R. C., Shiu, T. F., and Yang, C. M. (2010) Deletion of the FHL2 gene attenuates the formation of atherosclerotic lesions after a cholesterol-enriched diet. Life Sci. 86, 365-371.
    • (2010) Life Sci. , vol.86 , pp. 365-371
    • Chu, P.H.1    Yeh, H.I.2    Wu, H.H.3    Hong, R.C.4    Shiu, T.F.5    Yang, C.M.6
  • 45
    • 60649099790 scopus 로고    scopus 로고
    • Drosophila HNF4 regulates lipid mobilization and beta-oxidation
    • Palanker, L., Tennessen, J. M., Lam, G., and Thummel, C. S. (2009) Drosophila HNF4 regulates lipid mobilization and beta-oxidation. Cell Metab. 9, 228-239.
    • (2009) Cell Metab. , vol.9 , pp. 228-239
    • Palanker, L.1    Tennessen, J.M.2    Lam, G.3    Thummel, C.S.4
  • 46
    • 0034353203 scopus 로고    scopus 로고
    • Influence of 699C T and 1080C T polymorphisms of the cystathionine β-synthase gene on plasma homocysteine levels
    • DOI 10.1034/j.1399-0004.2000.580605.x
    • Aras, O., Hanson, N. Q., Yang, F., and Tsai, M. Y. (2000) Influence of 699C-T and 1080C-T polymorphisms of the cystathionine betasynthase gene on plasma homocysteine levels. Clin. Genet. 58, 455-459. (Pubitemid 32000747)
    • (2000) Clinical Genetics , vol.58 , Issue.6 , pp. 455-459
    • Aras, O.1    Hanson, N.Q.2    Yang, F.3    Tsai, M.Y.4
  • 47
    • 33748756864 scopus 로고    scopus 로고
    • Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I protein synthesis and enhancing HDL cholesterol clearance
    • DOI 10.1161/01.RES.0000242559.42077.22, PII 0000301220060915000007
    • Liao, D., Tan, H., Hui, R., Li, Z., Jiang, X., Gaubatz, J., Yang, F., Durante, W., Chan, L., Schafer, A. I., Pownall, H. J., Yang, X., and Wang, H. (2006) Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance. Circ. Res. 99, 598-606. (Pubitemid 44401451)
    • (2006) Circulation Research , vol.99 , Issue.6 , pp. 598-606
    • Liao, D.1    Tan, H.2    Hui, R.3    Li, Z.4    Jiang, X.5    Gaubatz, J.6    Yang, F.7    Durante, W.8    Chan, L.9    Schafer, A.I.10    Pownall, H.J.11    Yang, X.12    Wang, H.13
  • 49
    • 79955556527 scopus 로고    scopus 로고
    • Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis
    • Erlich, Y., Edvardson, S., Hodges, E., Zenvirt, S., Thekkat, P., Shaag, A., Dor, T., Hannon, G. J., and Elpeleg, O. (2011) Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis. Genome Res. 21, 658-664.
    • (2011) Genome Res. , vol.21 , pp. 658-664
    • Erlich, Y.1    Edvardson, S.2    Hodges, E.3    Zenvirt, S.4    Thekkat, P.5    Shaag, A.6    Dor, T.7    Hannon, G.J.8    Elpeleg, O.9


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