Application of GC/MS-based metabonomic profiling in studying the lipid-regulating effects of Ginkgo biloba extract on diet-induced hyperlipidemia in rats

Acta Pharmacologica Sinica

Volumn 30, Issue 12, 2009, Pages 1674-1687

  Zhang, Qi ^a,b   Wang, Guang Ji ^a   A, Ji Ye ^a   Wu, Di ^c   Zhu, Ling Ling ^b   Ma, Bo ^b   Du, Yu ^b  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NANJING TECH UNIVERSITY   (China)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

GC MS; Ginkgo biloba extract; Hyperlipidemia; Lipid regulating effect; Metabonomics

Indexed keywords

ACETIC ACID; ADIPIC ACID; ARACHIDONIC ACID; ASPARTIC ACID; BILE ACID; BUTYRIC ACID; CHOLESTEROL; CITRIC ACID; CREATININE; CYSTEINE; GALACTOSE; GINKGO BILOBA EXTRACT; GLUCOSE; GLUTAMINE; GLYCINE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LINOLEIC ACID; LIPOPROTEIN LIPASE; LIVER TRIACYLGLYCEROL LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ORNITHINE; PALMITIC ACID; PROLINE; SERINE; SORBITOL; THREONINE; TYROSINE; UNINDEXED DRUG; UREA; VALINE;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE FLOW; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; FATTY ACID BLOOD LEVEL; GENE EXPRESSION PROFILING; GINKGO BILOBA; GLUCOSE BLOOD LEVEL; HYPERLIPIDEMIA; LIPID ANALYSIS; LIPID DIET; LIPID METABOLISM; MALE; MASS FRAGMENTOGRAPHY; METABOLITE; NONHUMAN; PLANT LEAF; PRINCIPAL COMPONENT ANALYSIS; RAT; SCORING SYSTEM; STEROL EXCRETION; TRIACYLGLYCEROL BLOOD LEVEL;

ACYL COENZYME A; ANIMALS; BILE ACIDS AND SALTS; CHOLESTEROL, HDL; CHOLESTEROL, LDL; DIETARY FATS; FATTY ACIDS, UNSATURATED; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GINKGO BILOBA; HYPERLIPIDEMIAS; LIPASE; LIPID METABOLISM; LIPOPROTEIN LIPASE; MALE; METABOLOME; METABOLOMICS; PHYTOTHERAPY; PLANT EXTRACTS; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, WISTAR;

EID: 74949095844     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2009.173     Document Type: Article

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